4jus - Revision history

OCA at 19:23, 29 May 2024

2024-05-29T19:23:48Z

←Older revision		Revision as of 19:23, 29 May 2024
Line 1:		Line 1:

	==Crystal structure of a fragment of Human HSPB6==		==Crystal structure of a fragment of Human HSPB6==
-	<StructureSection load='4jus' size='340' side='right'caption='[[4jus]]' scene=''>	+	<StructureSection load='4jus' size='340' side='right'caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4jus]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUS FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [https://pdbe.org/4jus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [https://www.ebi.ac.uk/pdbsum/4jus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [https://pdbe.org/4jus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [https://www.ebi.ac.uk/pdbsum/4jus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HSPB6_HUMAN HSPB6_HUMAN]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ATP-independent small heat-shock proteins (sHSPs) are an essential component of the cellular chaperoning machinery. Under both normal and stress conditions, sHSPs bind partially unfolded proteins and prevent their irreversible aggregation. Canonical vertebrate sHSPs, such as the alpha-crystallins, form large polydisperse oligomers from which smaller, functionally active subspecies dissociate. Here we focus on human HSPB6 which, despite having considerable homology to the alpha-crystallins in both the N-terminal region and the signature alpha-crystallin domain (ACD), only forms dimers in solution that represent the basic chaperoning subspecies. We addressed the three-dimensional structure and functional properties of HSPB6 in a hybrid study employing X-ray crystallography, solution small-angle X-ray scattering (SAXS), mutagenesis, size-exclusion chromatography and chaperoning assays. The crystal structure of a proteolytically stable fragment reveals typical ACD dimers which further form tetrameric assemblies as a result of extensive inter-dimer patching of the beta4/beta8 grooves. The patching is surprisingly mediated by tripeptide motifs, found in the N-terminal domain directly adjacent to the ACD, that are resembling but distinct from the canonical IxI sequence commonly binding this groove. By combining the crystal structure with SAXS data for the full-length protein, we derive a molecular model of the latter. In solution, HSPB6 shows a strong attractive self-interaction, a property that correlates with its chaperoning activity. Both properties are dictated by the unstructured yet compact N-terminal domain, specifically a region highly conserved across vertebrate sHSPs.
		+
		+	Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6.,Weeks SD, Baranova EV, Heirbaut M, Beelen S, Shkumatov AV, Gusev NB, Strelkov SV J Struct Biol. 2013 Dec 29. pii: S1047-8477(13)00336-5. doi:, 10.1016/j.jsb.2013.12.009. PMID:24382496<ref>PMID:24382496</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4jus" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
	[[Category: Baranova EV]]		[[Category: Baranova EV]]

OCA at 10:45, 31 August 2022

2022-08-31T10:45:19Z

←Older revision		Revision as of 10:45, 31 August 2022
Line 1:		Line 1:

	==Crystal structure of a fragment of Human HSPB6==		==Crystal structure of a fragment of Human HSPB6==
-	<StructureSection load='4jus' size='340' side='right'caption='[[4jus]]~~, [[Resolution\|resolution]] 2.50Å~~' scene=''>	+	<StructureSection load='4jus' size='340' side='right'caption='[[4jus]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>~~[[4jus]] is a 8 chain structure.~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUS FirstGlance]. <br>	+	<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUS FirstGlance]. <br>
-	</td></tr>~~<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [https://pdbe.org/4jus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [https://www.ebi.ac.uk/pdbsum/4jus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4jut\|4jut]]</div></td></tr>~~	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [https://pdbe.org/4jus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [https://www.ebi.ac.uk/pdbsum/4jus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>	+
	</table>		</table>
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	ATP-independent small heat-shock proteins (sHSPs) are an essential component of the cellular chaperoning machinery. Under both normal and stress conditions, sHSPs bind partially unfolded proteins and prevent their irreversible aggregation. Canonical vertebrate sHSPs, such as the alpha-crystallins, form large polydisperse oligomers from which smaller, functionally active subspecies dissociate. Here we focus on human HSPB6 which, despite having considerable homology to the alpha-crystallins in both the N-terminal region and the signature alpha-crystallin domain (ACD), only forms dimers in solution that represent the basic chaperoning subspecies. We addressed the three-dimensional structure and functional properties of HSPB6 in a hybrid study employing X-ray crystallography, solution small-angle X-ray scattering (SAXS), mutagenesis, size-exclusion chromatography and chaperoning assays. The crystal structure of a proteolytically stable fragment reveals typical ACD dimers which further form tetrameric assemblies as a result of extensive inter-dimer patching of the beta4/beta8 grooves. The patching is surprisingly mediated by tripeptide motifs, found in the N-terminal domain directly adjacent to the ACD, that are resembling but distinct from the canonical IxI sequence commonly binding this groove. By combining the crystal structure with SAXS data for the full-length protein, we derive a molecular model of the latter. In solution, HSPB6 shows a strong attractive self-interaction, a property that correlates with its chaperoning activity. Both properties are dictated by the unstructured yet compact N-terminal domain, specifically a region highly conserved across vertebrate sHSPs.
-
-	Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6.,Weeks SD, Baranova EV, Heirbaut M, Beelen S, Shkumatov AV, Gusev NB, Strelkov SV J Struct Biol. 2013 Dec 29. pii: S1047-8477(13)00336-5. doi:, 10.1016/j.jsb.2013.12.009. PMID:24382496<ref>PMID:24382496</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4jus" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]		*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Baranova~~, E V~~]]	+	[[Category: Baranova EV]]
-	[[Category: Beelen, S]]	+	[[Category: Beelen S]]
-	[[Category: Gusev~~, N B~~]]	+	[[Category: Gusev NB]]
-	[[Category: Heirbaut, M]]	+	[[Category: Heirbaut M]]
-	[[Category: Strelkov~~, S V~~]]	+	[[Category: Strelkov SV]]
-	[[Category: Weeks~~, S D]]~~	+	[[Category: Weeks SD]]
-	~~[[Category: Alpha-crystallin domain]]~~	+
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Small heat shock protein~~]]	+

OCA at 05:02, 25 August 2022

2022-08-25T05:02:56Z

←Older revision		Revision as of 05:02, 25 August 2022
Line 1:		Line 1:

	==Crystal structure of a fragment of Human HSPB6==		==Crystal structure of a fragment of Human HSPB6==
-	<StructureSection load='4jus' size='340' side='right' caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='4jus' size='340' side='right'caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4jus]] is a 8 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Human Human]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4JUS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4jus]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4JUS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">~~[[4jut\|4jut]]~~<~~/td></tr>~~	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4jut\|4jut]]</div></td></tr>
-	~~<tr id~~='~~gene~~'~~><td class="sblockLbl"><b~~>[[~~Gene~~\|~~Gene:~~]]</b>~~</td><td class="sblockDat">HSPB6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [https://pdbe.org/4jus PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [https://www.ebi.ac.uk/pdbsum/4jus PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [~~http~~://pdbe.org/4jus PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4jus PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 18:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 4jus" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4jus" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Large Structures]]
	[[Category: Baranova, E V]]		[[Category: Baranova, E V]]
	[[Category: Beelen, S]]		[[Category: Beelen, S]]

OCA at 09:23, 4 August 2016

2016-08-04T09:23:00Z

←Older revision		Revision as of 09:23, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of a fragment of Human HSPB6==		==Crystal structure of a fragment of Human HSPB6==
	<StructureSection load='4jus' size='340' side='right' caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='4jus' size='340' side='right' caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jut\|4jut]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jut\|4jut]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSPB6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSPB6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [http://www.ebi.ac.uk/pdbsum/4jus PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [http://pdbe.org/4jus PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [http://www.ebi.ac.uk/pdbsum/4jus PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4jus ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4jus" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 18:39, 21 December 2014

2014-12-21T18:39:55Z

←Older revision		Revision as of 18:39, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4jus\| PDB~~=4jus \| ~~SCENE~~= }}	+	==Crystal structure of a fragment of Human HSPB6==
-	===~~Crystal structure of~~ a ~~fragment of~~ Human HSPB6===	+	<StructureSection load='4jus' size='340' side='right' caption='[[4jus]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24382496}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4jus]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JUS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4jut\|4jut]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSPB6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jus FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jus OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jus RCSB], [http://www.ebi.ac.uk/pdbsum/4jus PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	ATP-independent small heat-shock proteins (sHSPs) are an essential component of the cellular chaperoning machinery. Under both normal and stress conditions, sHSPs bind partially unfolded proteins and prevent their irreversible aggregation. Canonical vertebrate sHSPs, such as the alpha-crystallins, form large polydisperse oligomers from which smaller, functionally active subspecies dissociate. Here we focus on human HSPB6 which, despite having considerable homology to the alpha-crystallins in both the N-terminal region and the signature alpha-crystallin domain (ACD), only forms dimers in solution that represent the basic chaperoning subspecies. We addressed the three-dimensional structure and functional properties of HSPB6 in a hybrid study employing X-ray crystallography, solution small-angle X-ray scattering (SAXS), mutagenesis, size-exclusion chromatography and chaperoning assays. The crystal structure of a proteolytically stable fragment reveals typical ACD dimers which further form tetrameric assemblies as a result of extensive inter-dimer patching of the beta4/beta8 grooves. The patching is surprisingly mediated by tripeptide motifs, found in the N-terminal domain directly adjacent to the ACD, that are resembling but distinct from the canonical IxI sequence commonly binding this groove. By combining the crystal structure with SAXS data for the full-length protein, we derive a molecular model of the latter. In solution, HSPB6 shows a strong attractive self-interaction, a property that correlates with its chaperoning activity. Both properties are dictated by the unstructured yet compact N-terminal domain, specifically a region highly conserved across vertebrate sHSPs.

-	~~==About this Structure==~~	+	Molecular structure and dynamics of the dimeric human small heat shock protein HSPB6.,Weeks SD, Baranova EV, Heirbaut M, Beelen S, Shkumatov AV, Gusev NB, Strelkov SV J Struct Biol. 2013 Dec 29. pii: S1047-8477(13)00336-5. doi:, 10.1016/j.jsb.2013.12.009. PMID:24382496<ref>PMID:24382496</ref>
-	~~[[4jus]] is a 8 chain~~ structure. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.ac.~~il/oca-bin/ocashort?id=4JUS OCA]~~.	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024382496</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	[[Category: Baranova, E V.]]	+	== References ==
-	[[Category: Beelen, S.]]	+	<references/>
-	[[Category: Gusev, N B.]]	+	__TOC__
-	[[Category: Heirbaut, M.]]	+	</StructureSection>
-	[[Category: Strelkov, S V.]]	+	[[Category: Human]]
-	[[Category: Weeks, S D.]]	+	[[Category: Baranova, E V]]
		+	[[Category: Beelen, S]]
		+	[[Category: Gusev, N B]]
		+	[[Category: Heirbaut, M]]
		+	[[Category: Strelkov, S V]]
		+	[[Category: Weeks, S D]]
	[[Category: Alpha-crystallin domain]]		[[Category: Alpha-crystallin domain]]
	[[Category: Chaperone]]		[[Category: Chaperone]]
	[[Category: Small heat shock protein]]		[[Category: Small heat shock protein]]

OCA at 11:14, 5 February 2014

2014-02-05T11:14:06Z

←Older revision		Revision as of 11:14, 5 February 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4jus\| PDB=4jus \| SCENE= }}
		+	===Crystal structure of a fragment of Human HSPB6===
		+	{{ABSTRACT_PUBMED_24382496}}

-	~~The entry~~ 4jus is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
		+	[[4jus]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUS OCA].

-	~~Authors~~: ~~Weeks, S.D.,~~ Baranova, E.V., Beelen, S.~~, Heirbaut, M.,~~ Gusev, N.B., Strelkov, S.V.	+	==Reference==
-		+	<ref group="xtra">PMID:024382496</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Crystal structure of a fragment of Human HSPB6~~	+	[[Category: Baranova, E V.]]
		+	[[Category: Beelen, S.]]
		+	[[Category: Gusev, N B.]]
		+	[[Category: Heirbaut, M.]]
		+	[[Category: Strelkov, S V.]]
		+	[[Category: Weeks, S D.]]
		+	[[Category: Alpha-crystallin domain]]
		+	[[Category: Chaperone]]
		+	[[Category: Small heat shock protein]]

OCA at 03:24, 20 September 2013

2013-09-20T03:24:38Z

←Older revision		Revision as of 03:24, 20 September 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4jus is ON HOLD	+	The entry 4jus is ON HOLD until Paper Publication

	Authors: Weeks, S.D., Baranova, E.V., Beelen, S., Heirbaut, M., Gusev, N.B., Strelkov, S.V.		Authors: Weeks, S.D., Baranova, E.V., Beelen, S., Heirbaut, M., Gusev, N.B., Strelkov, S.V.

	Description: Crystal structure of a fragment of Human HSPB6		Description: Crystal structure of a fragment of Human HSPB6

OCA: Protected "4jus" [edit=sysop:move=sysop]

2013-04-04T01:03:36Z

Protected "4jus" [edit=sysop:move=sysop]

←Older revision

Revision as of 01:03, 4 April 2013

OCA: New page: '''Unreleased structure''' The entry 4jus is ON HOLD Authors: Weeks, S.D., Baranova, E.V., Beelen, S., Heirbaut, M., Gusev, N.B., Strelkov, S.V. Description: Crystal structure of a fra...

2013-04-04T01:03:35Z

New page: '''Unreleased structure''' The entry 4jus is ON HOLD Authors: Weeks, S.D., Baranova, E.V., Beelen, S., Heirbaut, M., Gusev, N.B., Strelkov, S.V. Description: Crystal structure of a fra...

New page

'''Unreleased structure'''

The entry 4jus is ON HOLD

Authors: Weeks, S.D., Baranova, E.V., Beelen, S., Heirbaut, M., Gusev, N.B., Strelkov, S.V.

Description: Crystal structure of a fragment of Human HSPB6