4k0o - Revision history

OCA at 14:26, 8 November 2023

2023-11-08T14:26:52Z

←Older revision		Revision as of 14:26, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K0O FirstGlance]. <br>		<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K0O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.15Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [https://pdbe.org/4k0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [https://www.ebi.ac.uk/pdbsum/4k0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0o ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [https://pdbe.org/4k0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [https://www.ebi.ac.uk/pdbsum/4k0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0o ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:34, 30 November 2022

2022-11-30T11:34:50Z

←Older revision		Revision as of 11:34, 30 November 2022
Line 1:		Line 1:

	==F17b-G lectin domain with bound GlcNAc(beta1-3)Gal==		==F17b-G lectin domain with bound GlcNAc(beta1-3)Gal==
-	<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>	+	<StructureSection load='4k0o' size='340' side='right'caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacillus_coli"_migula_1895 "bacillus~~ coli~~" migula 1895~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4K0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K0O FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:~~NICKEL+~~(II)~~+ION~~'>~~NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4~~</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~ALY~~:N(6)~~-ACETYLLYSINE~~'>~~ALY~~</scene><~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [https://pdbe.org/4k0o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [https://www.ebi.ac.uk/pdbsum/4k0o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0o ProSAT]</span></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>~~	+
-	~~<tr id='gene~~'>~~<td class="sblockLbl"><b>[[Gene\|Gene:]]~~</b>~~</td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [~~http~~://pdbe.org/4k0o PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4k0o PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0o ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.	+	[https://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 20:

	==See Also==		==See Also==
-	*[[Adhesin\|Adhesin]]	+	*[[Adhesin 3D structures\|Adhesin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacillus~~ coli ~~migula 1895~~]]	+	[[Category: Escherichia coli]]
-	[[Category: Bouckaert, J]]	+	[[Category: Large Structures]]
-	[[Category: Buts, L]]	+	[[Category: Bouckaert J]]
-	[[Category: Loris, R]]	+	[[Category: Buts L]]
-	[[Category: Moonens, K]]	+	[[Category: Loris R]]
-	~~[[Category: Acetylation of lysine side chain]]~~	+	[[Category: Moonens K]]
-	~~[[Category: Carbohydrate receptor]]~~	+
-	~~[[Category: Cellular envelope]]~~	+
-	~~[[Category: Immunoglobulin-like fold]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 07:24, 23 December 2016

2016-12-23T07:24:58Z

←Older revision		Revision as of 07:24, 23 December 2016
Line 1:		Line 1:
		+
	==F17b-G lectin domain with bound GlcNAc(beta1-3)Gal==		==F17b-G lectin domain with bound GlcNAc(beta1-3)Gal==
	<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>
Line 7:		Line 8:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://pdbe.org/4k0o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k0o ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4k0o" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Adhesin\|Adhesin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:13, 25 February 2015

2015-02-25T08:13:13Z

←Older revision		Revision as of 08:13, 25 February 2015
Line 2:		Line 2:
	<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>		<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Escherichia_coli Escherichia~~ coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K0O FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K0O FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 ~~Escherichia~~ coli])</td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.		[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Fimbriae are long, proteinaceous adhesion organelles expressed on the bacterial envelope, evolutionarily adapted by Escherichia coli strains for the colonization of epithelial linings. Using glycan arrays of the Consortium for Functional Glycomics (CFG), the lectin domains were screened of the fimbrial adhesins F17G and FedF from enterotoxigenic E. coli (ETEC) and of the FimH adhesin from uropathogenic E. coli. This has led to the discovery of a more specific receptor for F17G, GlcNAcb1,3Gal. No significant differences emerged from the glycan binding profiles of the F17G lectin domains from five different E. coli strains. However, strain-dependent amino acid variations, predominantly towards the positively charged arginine, were indicated by sulfate binding in FedF and F17G crystal structures. For FedF, no significant binders could be observed on the CFG glycan array. Hence, a shotgun array was generated from microvilli scrapings of the distal jejunum of a 3-week old piglet about to be weaned. On this array, the blood group A type 1 hexasaccharide emerged as a receptor for the FedF lectin domain and remarkably also for F18-fimbriated E. coli. F17G was found to selectively recognize glycan species with a terminal GlcNAc, typifying intestinal mucins. In conclusion, F17G and FedF recognize long glycan sequences that could only be identified using the shotgun approach. Interestingly, ETEC strains display a large capacity to adapt their fimbrial adhesins to ecological niches via charge-driven interactions, congruent with binding to thick mucosal surfaces displaying an acidic gradient along the intestinal tract.
		+
		+	Structural Sampling of Glycan Interaction Profiles Reveals Mucosal Receptors for Fimbrial Adhesins of Enterotoxigenic Escherichia coli.,Lonardi E, Moonens K, Buts L, de Boer AR, Olsson JD, Weiss MS, Fabre E, Guerardel Y, Deelder AM, Oscarson S, Wuhrer M, Bouckaert J Biology (Basel). 2013 Jul 1;2(3):894-917. doi: 10.3390/biology2030894. PMID:24833052<ref>PMID:24833052</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Escherichia~~ coli]]	+	[[Category: Bacillus coli migula 1895]]
	[[Category: Bouckaert, J]]		[[Category: Bouckaert, J]]
	[[Category: Buts, L]]		[[Category: Buts, L]]

OCA at 07:51, 25 December 2014

2014-12-25T07:51:59Z

←Older revision		Revision as of 07:51, 25 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 15:33, 21 December 2014

2014-12-21T15:33:47Z

←Older revision		Revision as of 15:33, 21 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4k0o\| PDB=4k0o \| SCENE= }}~~	+	==F17b-G lectin domain with bound GlcNAc(beta1-3)Gal==
-	===F17b-G lectin domain with bound GlcNAc(beta1-3)Gal===	+	<StructureSection load='4k0o' size='340' side='right' caption='[[4k0o]], [[Resolution\|resolution]] 2.15Å' scene=''>
-		+	== Structural highlights ==
-	==~~Function~~==	+	<table><tr><td colspan='2'>[[4k0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K0O FirstGlance]. <br>
-	[[~~http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX~~]] ~~Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli~~, ~~leading to colonization of the intestinal tissue, and diarrhea or septicemia~~. ~~Also confers adhesiveness to laminin and basement membranes.~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=MBG:METHYL-BETA-GALACTOSE'>MBG</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene></td></tr>
-	==~~About this Structure~~==	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[1o9v\|1o9v]], [[2bs7\|2bs7]], [[2bs8\|2bs8]], [[3ffo\|3ffo]]</td></tr>
-	[[4k0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA].	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">f17bG, F17G ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k0o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k0o OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k0o RCSB], [http://www.ebi.ac.uk/pdbsum/4k0o PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Escherichia coli]]		[[Category: Escherichia coli]]
-	[[Category: Bouckaert, J.]]	+	[[Category: Bouckaert, J]]
-	[[Category: Buts, L.]]	+	[[Category: Buts, L]]
-	[[Category: Loris, R.]]	+	[[Category: Loris, R]]
-	[[Category: Moonens, K.]]	+	[[Category: Moonens, K]]
	[[Category: Acetylation of lysine side chain]]		[[Category: Acetylation of lysine side chain]]
	[[Category: Carbohydrate receptor]]		[[Category: Carbohydrate receptor]]

OCA: Protected "4k0o" [edit=sysop:move=sysop]

2013-04-17T20:38:48Z

Protected "4k0o" [edit=sysop:move=sysop]

←Older revision

Revision as of 20:38, 17 April 2013

OCA: New page: {{STRUCTURE_4k0o| PDB=4k0o | SCENE= }} ===F17b-G lectin domain with bound GlcNAc(beta1-3)Gal=== ==Function== http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX Essential fimb...

2013-04-17T20:38:44Z

New page: {{STRUCTURE_4k0o| PDB=4k0o | SCENE= }} ===F17b-G lectin domain with bound GlcNAc(beta1-3)Gal=== ==Function== http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX Essential fimb...

New page

{{STRUCTURE_4k0o| PDB=4k0o | SCENE= }}
===F17b-G lectin domain with bound GlcNAc(beta1-3)Gal===

==Function==
[[http://www.uniprot.org/uniprot/F17BG_ECOLX F17BG_ECOLX]] Essential fimbrial adhesion factor that mediates binding to N-acetylglucosamine-containing receptors in the host intestinal microvilli, leading to colonization of the intestinal tissue, and diarrhea or septicemia. Also confers adhesiveness to laminin and basement membranes.

==About this Structure==
[[4k0o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K0O OCA].
[[Category: Escherichia coli]]
[[Category: Bouckaert, J.]]
[[Category: Buts, L.]]
[[Category: Loris, R.]]
[[Category: Moonens, K.]]
[[Category: Acetylation of lysine side chain]]
[[Category: Carbohydrate receptor]]
[[Category: Cellular envelope]]
[[Category: Immunoglobulin-like fold]]
[[Category: Lectin]]
[[Category: Sugar binding protein]]