4k6v - Revision history

OCA at 06:49, 3 April 2024

2024-04-03T06:49:36Z

←Older revision		Revision as of 06:49, 3 April 2024
Line 10:		Line 10:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/Q64823_9ADEN Q64823_9ADEN]		[https://www.uniprot.org/uniprot/Q64823_9ADEN Q64823_9ADEN]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Adenovirus type 37 (Ad37) is one of the principal agents responsible for epidemic keratoconjunctivitis (EKC), a severe ocular infection that remains without any available treatment. Recently, a trivalent sialic acid derivative (, Angew. Chem. Int. Ed., 2011, , 6519) was shown to function as a highly potent inhibitor of Ad37, efficiently preventing the attachment of the virion to the host cells and subsequent infection. Here, new trivalent sialic acid derivatives were designed, synthesized and their inhibitory properties against Ad37 infection of the human corneal epithelial cells were investigated. In comparison to , the best compound () was found to be over three orders of magnitude more potent in a cell-attachment assay (IC50 = 1.4 nM) and about 140 times more potent in a cell-infection assay (IC50 = 2.9 nM). X-ray crystallographic analysis demonstrated a trivalent binding mode of all compounds to the Ad37 fiber knob. For the most potent compound ophthalmic toxicity in rabbits was investigated and it was concluded that repeated eye administration did not cause any adverse effects.
-
-	Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.,Caraballo R, Saleeb M, Bauer J, Liaci AM, Chandra N, Storm RJ, Frangsmyr L, Qian W, Stehle T, Arnberg N, Elofsson M Org Biomol Chem. 2015 Jul 16. PMID:26177934<ref>PMID:26177934</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4k6v" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:27, 29 November 2023

2023-11-29T14:27:39Z

←Older revision		Revision as of 14:27, 29 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D37 Human adenovirus D37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6V FirstGlance]. <br>		<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D37 Human adenovirus D37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [https://pdbe.org/4k6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [https://www.ebi.ac.uk/pdbsum/4k6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [https://pdbe.org/4k6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [https://www.ebi.ac.uk/pdbsum/4k6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6v ProSAT]</span></td></tr>
	</table>		</table>

OCA at 11:42, 30 November 2022

2022-11-30T11:42:31Z

←Older revision		Revision as of 11:42, 30 November 2022
Line 1:		Line 1:

	==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407==		==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407==
-	<StructureSection load='4k6v' size='340' side='right' caption='[[4k6v]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='4k6v' size='340' side='right'caption='[[4k6v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Adenovirus_type_37 Adenovirus type 37~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4K6V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_adenovirus_D37 Human adenovirus D37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4K6V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4k6t\|4k6t]], [[4k6u\|4k6u]], [[4k6w\|4k6w]], [[3n0i\|3n0i]], [[1uxe\|1uxe]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [https://pdbe.org/4k6v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [https://www.ebi.ac.uk/pdbsum/4k6v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6v ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=52275 Adenovirus type 37])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [~~http~~://pdbe.org/4k6v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4k6v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6v ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q64823_9ADEN Q64823_9ADEN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Adenovirus type 37~~]]	+	[[Category: Human adenovirus D37]]
-	[[Category: ~~Bauer, J~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Stehle, T~~]]	+	[[Category: Bauer J]]
-	[[Category: ~~Adenovirus]]~~	+	[[Category: Stehle T]]
-	~~[[Category: Carbohydrate mimic]]~~	+
-	~~[[Category: Fiber knob]]~~	+
-	~~[[Category: Multivalent ligand]]~~	+
-	~~[[Category: Protein carbohydrate interaction]]~~	+
-	~~[[Category: Viral protein~~]]	+

OCA at 09:18, 15 November 2017

2017-11-15T09:18:52Z

←Older revision		Revision as of 09:18, 15 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407==		==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407==
	<StructureSection load='4k6v' size='340' side='right' caption='[[4k6v]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='4k6v' size='340' side='right' caption='[[4k6v]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Adenovirus_type_37 Adenovirus type 37]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4k6t\|4k6t]], [[4k6u\|4k6u]], [[4k6w\|4k6w]], [[3n0i\|3n0i]], [[1uxe\|1uxe]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4k6t\|4k6t]], [[4k6u\|4k6u]], [[4k6w\|4k6w]], [[3n0i\|3n0i]], [[1uxe\|1uxe]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [http://www.ebi.ac.uk/pdbsum/4k6v PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">L5 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=52275 Adenovirus type 37])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [http://pdbe.org/4k6v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [http://www.ebi.ac.uk/pdbsum/4k6v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4k6v ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 15:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4k6v" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Adenovirus type 37]]
	[[Category: Bauer, J]]		[[Category: Bauer, J]]
	[[Category: Stehle, T]]		[[Category: Stehle, T]]

OCA at 08:39, 29 July 2015

2015-07-29T08:39:26Z

←Older revision		Revision as of 08:39, 29 July 2015
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [http://www.ebi.ac.uk/pdbsum/4k6v PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [http://www.ebi.ac.uk/pdbsum/4k6v PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Adenovirus type 37 (Ad37) is one of the principal agents responsible for epidemic keratoconjunctivitis (EKC), a severe ocular infection that remains without any available treatment. Recently, a trivalent sialic acid derivative (, Angew. Chem. Int. Ed., 2011, , 6519) was shown to function as a highly potent inhibitor of Ad37, efficiently preventing the attachment of the virion to the host cells and subsequent infection. Here, new trivalent sialic acid derivatives were designed, synthesized and their inhibitory properties against Ad37 infection of the human corneal epithelial cells were investigated. In comparison to , the best compound () was found to be over three orders of magnitude more potent in a cell-attachment assay (IC50 = 1.4 nM) and about 140 times more potent in a cell-infection assay (IC50 = 2.9 nM). X-ray crystallographic analysis demonstrated a trivalent binding mode of all compounds to the Ad37 fiber knob. For the most potent compound ophthalmic toxicity in rabbits was investigated and it was concluded that repeated eye administration did not cause any adverse effects.
		+
		+	Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells.,Caraballo R, Saleeb M, Bauer J, Liaci AM, Chandra N, Storm RJ, Frangsmyr L, Qian W, Stehle T, Arnberg N, Elofsson M Org Biomol Chem. 2015 Jul 16. PMID:26177934<ref>PMID:26177934</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 08:08, 25 January 2015

2015-01-25T08:08:45Z

←Older revision		Revision as of 08:08, 25 January 2015
Line 9:		Line 9:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Bauer, J.]]	+	[[Category: Bauer, J]]
-	[[Category: Stehle, T.]]	+	[[Category: Stehle, T]]
	[[Category: Adenovirus]]		[[Category: Adenovirus]]
	[[Category: Carbohydrate mimic]]		[[Category: Carbohydrate mimic]]

OCA at 11:37, 22 October 2014

2014-10-22T11:37:09Z

←Older revision		Revision as of 11:37, 22 October 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of Ad37 fiber knob in complex with trivalent sialic acid inhibitor ME0407==
-		+	<StructureSection load='4k6v' size='340' side='right' caption='[[4k6v]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~The entry~~ 4k6v is ~~ON HOLD until Oct 22 2015~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4k6v]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4K6V FirstGlance]. <br>
-	~~Authors~~: ~~Stehle~~, T., Bauer, J.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=18D:3,5-DIDEOXY-5-(PROPANOYLAMINO)-D-GLYCERO-ALPHA-D-GALACTO-NON-2-ULOPYRANOSONIC+ACID'>18D</scene>, <scene name='pdbligand=1P4:3,3,3-[NITRILOTRIS(METHANEDIYL-1H-1,2,3-TRIAZOLE-4,1-DIYL)]TRIPROPAN-1-OL'>1P4</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4k6t\|4k6t]], [[4k6u\|4k6u]], [[4k6w\|4k6w]], [[3n0i\|3n0i]], [[1uxe\|1uxe]]</td></tr>
-	~~Description~~:	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4k6v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4k6v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4k6v RCSB], [http://www.ebi.ac.uk/pdbsum/4k6v PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bauer, J.]]
		+	[[Category: Stehle, T.]]
		+	[[Category: Adenovirus]]
		+	[[Category: Carbohydrate mimic]]
		+	[[Category: Fiber knob]]
		+	[[Category: Multivalent ligand]]
		+	[[Category: Protein carbohydrate interaction]]
		+	[[Category: Viral protein]]

OCA at 09:06, 20 October 2014

2014-10-20T09:06:01Z

←Older revision		Revision as of 09:06, 20 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4k6v is ON HOLD until Oct 15 2015	+	The entry 4k6v is ON HOLD until Oct 22 2015

	Authors: Stehle, T., Bauer, J.		Authors: Stehle, T., Bauer, J.

	Description:		Description:

OCA at 09:32, 16 July 2014

2014-07-16T09:32:49Z

←Older revision		Revision as of 09:32, 16 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4k6v is ON HOLD until ~~Jul 16~~ 2015	+	The entry 4k6v is ON HOLD until Oct 15 2015

	Authors: Stehle, T., Bauer, J.		Authors: Stehle, T., Bauer, J.

	Description:		Description:

OCA at 16:21, 3 March 2014

2014-03-03T16:21:27Z

←Older revision		Revision as of 16:21, 3 March 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4k6v is ON HOLD until ~~Paper Publication~~	+	The entry 4k6v is ON HOLD until Jul 16 2015

	Authors: Stehle, T., Bauer, J.		Authors: Stehle, T., Bauer, J.

	Description:		Description: