4kbd - Revision history

OCA at 12:56, 20 December 2023

2023-12-20T12:56:48Z

←Older revision		Revision as of 12:56, 20 December 2023
Line 1:		Line 1:

	==DNA STRUCTURE OF A MUTATED KB SITE==		==DNA STRUCTURE OF A MUTATED KB SITE==
-	<StructureSection load='4kbd' size='340' side='right'caption='[[4kbd~~]], [[NMR_Ensembles_of_Models \| 3 NMR models~~]]' scene=''>	+	<StructureSection load='4kbd' size='340' side='right'caption='[[4kbd]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [https://pdbe.org/4kbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [https://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbd ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [https://pdbe.org/4kbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [https://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 20:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Delepierre, M]]	+	[[Category: Delepierre M]]
-	[[Category: Hartmann, B]]	+	[[Category: Hartmann B]]
-	[[Category: Tisne, C]]	+	[[Category: Tisne C]]
-	~~[[Category: Deoxyribonucleic acid]]~~	+
-	~~[[Category: Dna]]~~	+
-	~~[[Category: Dna structure]]~~	+
-	~~[[Category: Modelling~~]]	+

OCA at 07:05, 16 March 2022

2022-03-16T07:05:14Z

←Older revision		Revision as of 07:05, 16 March 2022
Line 3:		Line 3:
	<StructureSection load='4kbd' size='340' side='right'caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>		<StructureSection load='4kbd' size='340' side='right'caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KBD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [~~http~~://pdbe.org/4kbd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbd ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [https://pdbe.org/4kbd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [https://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 08:48, 3 April 2019

2019-04-03T08:48:10Z

←Older revision		Revision as of 08:48, 3 April 2019
Line 1:		Line 1:

	==DNA STRUCTURE OF A MUTATED KB SITE==		==DNA STRUCTURE OF A MUTATED KB SITE==
-	<StructureSection load='4kbd' size='340' side='right' caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>	+	<StructureSection load='4kbd' size='340' side='right'caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Delepierre, M]]		[[Category: Delepierre, M]]
	[[Category: Hartmann, B]]		[[Category: Hartmann, B]]

OCA at 14:20, 11 August 2016

2016-08-11T14:20:31Z

←Older revision		Revision as of 14:20, 11 August 2016
Line 1:		Line 1:
		+
	==DNA STRUCTURE OF A MUTATED KB SITE==		==DNA STRUCTURE OF A MUTATED KB SITE==
	<StructureSection load='4kbd' size='340' side='right' caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>		<StructureSection load='4kbd' size='340' side='right' caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://pdbe.org/4kbd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kbd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 13:		Line 14:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4kbd" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:31, 4 January 2015

2015-01-04T12:31:19Z

←Older revision		Revision as of 12:31, 4 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 17:		Line 17:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Delepierre, M.]]	+	[[Category: Delepierre, M]]
-	[[Category: Hartmann, B.]]	+	[[Category: Hartmann, B]]
-	[[Category: Tisne, C.]]	+	[[Category: Tisne, C]]
	[[Category: Deoxyribonucleic acid]]		[[Category: Deoxyribonucleic acid]]
	[[Category: Dna]]		[[Category: Dna]]
	[[Category: Dna structure]]		[[Category: Dna structure]]
	[[Category: Modelling]]		[[Category: Modelling]]

OCA at 10:29, 16 June 2014

2014-06-16T10:29:32Z

←Older revision		Revision as of 10:29, 16 June 2014
Line 1:		Line 1:
-	[[~~Image~~:4kbd.~~png\|left\|200px~~]]	+	==DNA STRUCTURE OF A MUTATED KB SITE==
		+	<StructureSection load='4kbd' size='340' side='right' caption='[[4kbd]], [[NMR_Ensembles_of_Models \| 3 NMR models]]' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KBD FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	We present the solution structure of the nonpalindromic 16 bp DNA 5'd(CTGCTCACTTTCCAGG)3'. 5'd(CCTGGAAAGTGAGCAG)3' containing a mutated kappaB site for which the mutation of a highly conserved GGG tract of the native kappaB HIV-1 site to CTC abolishes NF-kappaB binding. 1H and 31P NMR spectroscopies have been used together with molecular modeling to determine the fine structure of the duplex. NMR data show evidence for a BI-BII equilibrium of the CpA.TpG steps at the 3'-end of the oligomer. Models for the extreme conformations reached by the mutated duplex (denoted 16M) are proposed in agreement with the NMR data. Since the distribution of BII sites is changed in the mutated duplex compared to that of the native duplex (denoted 16N), large differences are induced in the intrinsic structural properties of both duplexes. In particular, in BII structures, 16M shows a kink located at the 3'-end of the duplex, and in contrast, 16N exhibits an intrinsic global curvature toward the major groove. Whereas 16N can reach a conformation very favorable for the interaction with NF-kappaB, 16M cannot mimic such a conformation and, moreover, its deeper and narrower major groove could hinder the DNA-protein interactions.

-	~~{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}~~	+	NF-kappa B binding mechanism: a nuclear magnetic resonance and modeling study of a GGG --> CTC mutation.,Tisne C, Hartmann B, Delepierre M Biochemistry. 1999 Mar 30;38(13):3883-94. PMID:10194299<ref>PMID:10194299</ref>

-	~~===DNA STRUCTURE OF A MUTATED KB SITE===~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~{{ABSTRACT_PUBMED_10194299}}~~	+	== References ==
-		+	<references/>
-	~~==About this Structure==~~	+	__TOC__
-	~~[[4kbd]] is~~ a ~~2 chain structure~~. ~~Full experimental information is available from [http://oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4KBD OCA].~~	+	</StructureSection>
-		+
-	==~~Reference~~==	+
-	<~~ref group="xtra">PMID:010194299<~~/~~ref~~><~~references group="xtra"~~/>	+
	[[Category: Delepierre, M.]]		[[Category: Delepierre, M.]]
	[[Category: Hartmann, B.]]		[[Category: Hartmann, B.]]

OCA: Protected "4kbd" [edit=sysop:move=sysop]

2012-08-14T15:04:20Z

Protected "4kbd" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:04, 14 August 2012

OCA at 15:04, 14 August 2012

2012-08-14T15:04:18Z

←Older revision		Revision as of 15:04, 14 August 2012
Line 1:		Line 1:
-	{{Seed}}
	[[Image:4kbd.png\|left\|200px]]		[[Image:4kbd.png\|left\|200px]]

-	<!--
-	The line below this paragraph, containing "STRUCTURE_4kbd", creates the "Structure Box" on the page.
-	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	or leave the SCENE parameter empty for the default display.
-	-->
	{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}		{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}

	===DNA STRUCTURE OF A MUTATED KB SITE===		===DNA STRUCTURE OF A MUTATED KB SITE===

-
-	<!--
-	The line below this paragraph, {{ABSTRACT_PUBMED_10194299}}, adds the Publication Abstract to the page
-	(as it appears on PubMed at http://www.pubmed.gov), where 10194299 is the PubMed ID number.
-	-->
	{{ABSTRACT_PUBMED_10194299}}		{{ABSTRACT_PUBMED_10194299}}

	==About this Structure==		==About this Structure==
-	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].	+	[[4kbd]] is a 2 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].

	==Reference==		==Reference==
-	~~NF-kappa B binding mechanism: a nuclear magnetic resonance and modeling study of a GGG --> CTC mutation., Tisne C, Hartmann B, Delepierre M, Biochemistry. 1999 Mar 30;38(13):3883-94.~~ PMID:~~[http://www.ncbi.nlm.nih.gov~~/~~pubmed~~/~~10194299 10194299]~~	+	<ref group="xtra">PMID:010194299</ref><references group="xtra"/>
	[[Category: Delepierre, M.]]		[[Category: Delepierre, M.]]
	[[Category: Hartmann, B.]]		[[Category: Hartmann, B.]]
	[[Category: Tisne, C.]]		[[Category: Tisne, C.]]
	[[Category: Deoxyribonucleic acid]]		[[Category: Deoxyribonucleic acid]]
		+	[[Category: Dna]]
	[[Category: Dna structure]]		[[Category: Dna structure]]
	[[Category: Modelling]]		[[Category: Modelling]]
-	[[Category: Nmr]]
-
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:42:16 2008''

OCA at 10:42, 3 July 2008

2008-07-03T10:42:17Z

←Older revision		Revision as of 10:42, 3 July 2008
Line 1:		Line 1:
-	[[Image:4kbd.~~gif~~\|left\|200px]]	+	{{Seed}}
		+	[[Image:4kbd.png\|left\|200px]]

	<!--		<!--
Line 9:		Line 10:
	{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}		{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}

-	~~'''~~DNA STRUCTURE OF A MUTATED KB SITE~~'''~~	+	===DNA STRUCTURE OF A MUTATED KB SITE===


-	~~==Overview==~~	+	<!--
-	~~We present~~ the ~~solution structure of~~ the ~~nonpalindromic 16 bp DNA 5'd~~(CTGCTCACTTTCCAGG)3'. 5'd(CCTGGAAAGTGAGCAG)3' containing a mutated kappaB site for which the mutation of a highly conserved GGG tract of the native kappaB HIV-1 site to CTC abolishes NF-kappaB binding. 1H and 31P NMR spectroscopies have been used together with molecular modeling to determine the fine structure of the duplex. NMR data show evidence for a BI-BII equilibrium of the CpA.TpG steps at ~~the 3'-end of the oligomer~~. ~~Models for the extreme conformations reached by the mutated duplex (denoted 16M) are proposed in agreement with the NMR data~~. ~~Since the distribution of BII sites is changed in the mutated duplex compared to that of the native duplex (denoted 16N~~), ~~large differences are induced in~~ the ~~intrinsic structural properties of both duplexes~~. ~~In particular, in BII structures, 16M shows a kink located at the 3'~~-~~end of the duplex, and in contrast, 16N exhibits an intrinsic global curvature toward the major groove. Whereas 16N can reach a conformation very favorable for the interaction with NF~~-~~kappaB, 16M cannot mimic such a conformation and, moreover, its deeper and narrower major groove could hinder the DNA-protein interactions.~~	+	The line below this paragraph, {{ABSTRACT_PUBMED_10194299}}, adds the Publication Abstract to the page
		+	(as it appears on PubMed at http://www.pubmed.gov), where 10194299 is the PubMed ID number.
		+	-->
		+	{{ABSTRACT_PUBMED_10194299}}

	==About this Structure==		==About this Structure==
-	Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].	+	Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].

	==Reference==		==Reference==
Line 27:		Line 31:
	[[Category: Modelling]]		[[Category: Modelling]]
	[[Category: Nmr]]		[[Category: Nmr]]
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Sun May~~ ~~4 22~~:25:49 2008''	+
		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jul 3 13:42:16 2008''

OCA at 19:25, 4 May 2008

2008-05-04T19:25:50Z

←Older revision		Revision as of 19:25, 4 May 2008
Line 1:		Line 1:
	[[Image:4kbd.gif\|left\|200px]]		[[Image:4kbd.gif\|left\|200px]]

-	~~{{Structure~~	+	<!--
-	~~\|PDB= 4kbd \|SIZE=350\|CAPTION=~~ <~~scene name='initialview01'>4kbd</scene>~~	+	The line below this paragraph, containing "STRUCTURE_4kbd", creates the "Structure Box" on the page.
-	~~\|SITE=~~	+	You may change the PDB parameter (which sets the PDB file loaded into the applet)
-	~~\|LIGAND= <scene name='pdbligand=DA:2'~~-~~DEOXYADENOSINE~~-~~5'-MONOPHOSPHATE'>DA</scene>~~, ~~<scene name='pdbligand=DC:2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE'>DC</scene>~~, <scene ~~name='pdbligand=DG:2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE'>DG</scene>~~, ~~<scene name='pdbligand=DT:THYMIDINE~~-~~5'~~-~~MONOPHOSPHATE'>DT</scene~~>	+	or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-	\|~~ACTIVITY~~=	+	or leave the SCENE parameter empty for the default display.
-	\|~~GENE~~=	+	-->
-	~~\|DOMAIN=~~	+	{{STRUCTURE_4kbd\| PDB=4kbd \| SCENE= }}
-	~~\|RELATEDENTRY=~~	+
-	\|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kbd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kbd OCA], [http://www.ebi.ac.uk/pdbsum/4kbd PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=4kbd RCSB]</span>	+
-	}}	+

	'''DNA STRUCTURE OF A MUTATED KB SITE'''		'''DNA STRUCTURE OF A MUTATED KB SITE'''
Line 19:		Line 16:

	==About this Structure==		==About this Structure==
-	~~4KBD is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ].~~ Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].	+	Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBD OCA].

	==Reference==		==Reference==
	NF-kappa B binding mechanism: a nuclear magnetic resonance and modeling study of a GGG --> CTC mutation., Tisne C, Hartmann B, Delepierre M, Biochemistry. 1999 Mar 30;38(13):3883-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10194299 10194299]		NF-kappa B binding mechanism: a nuclear magnetic resonance and modeling study of a GGG --> CTC mutation., Tisne C, Hartmann B, Delepierre M, Biochemistry. 1999 Mar 30;38(13):3883-94. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10194299 10194299]
-	[[Category: Protein complex]]
	[[Category: Delepierre, M.]]		[[Category: Delepierre, M.]]
	[[Category: Hartmann, B.]]		[[Category: Hartmann, B.]]
	[[Category: Tisne, C.]]		[[Category: Tisne, C.]]
-	[[Category: ~~deoxyribonucleic~~ acid]]	+	[[Category: Deoxyribonucleic acid]]
-	[[Category: ~~dna~~ structure]]	+	[[Category: Dna structure]]
-	[[Category: ~~modelling~~]]	+	[[Category: Modelling]]
-	[[Category: ~~nmr~~]]	+	[[Category: Nmr]]
-		+	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:25:49 2008''
-	''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Mon Mar 31 05~~:39:13 2008''	+