4kl6 - Revision history

OCA at 16:00, 20 September 2023

2023-09-20T16:00:59Z

←Older revision		Revision as of 16:00, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_punctiforme_PCC_73102 Nostoc punctiforme PCC 73102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_punctiforme_PCC_73102 Nostoc punctiforme PCC 73102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [https://pdbe.org/4kl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [https://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.2Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [https://pdbe.org/4kl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [https://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	</div>		</div>
	<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:57, 7 December 2022

2022-12-07T08:57:25Z

←Older revision		Revision as of 08:57, 7 December 2022
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	<StructureSection load='4kl6' size='340' side='right'caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4kl6' size='340' side='right'caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_punctiforme_PCC_73102 Nostoc punctiforme PCC 73102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [https://pdbe.org/4kl6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [https://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [~~http~~://pdbe.org/4kl6 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B2J821_NOSP7 B2J821_NOSP7]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Aranko, A S~~]]	+	[[Category: Nostoc punctiforme PCC 73102]]
-	[[Category: ~~Iwai, H~~]]	+	[[Category: Aranko AS]]
-	[[Category: ~~Kajander, T~~]]	+	[[Category: Iwai H]]
-	[[Category: ~~Oeemig, J S~~]]	+	[[Category: Kajander T]]
-	[[Category: ~~Domain swapped]]~~	+	[[Category: Oeemig JS]]
-	~~[[Category: Hint]]~~	+
-	~~[[Category: Intein]]~~	+
-	~~[[Category: Npudnae inten]]~~	+
-	~~[[Category: Unknown function~~]]	+

OCA at 04:57, 13 February 2020

2020-02-13T04:57:52Z

←Older revision		Revision as of 04:57, 13 February 2020
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	==Crystal structure of dimeric form of NpuDnaE intein==		==Crystal structure of dimeric form of NpuDnaE intein==
-	<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4kl6' size='340' side='right'caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[DNA polymerase 3D structures\|DNA polymerase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Aranko, A S]]		[[Category: Aranko, A S]]
	[[Category: Iwai, H]]		[[Category: Iwai, H]]

OCA at 12:03, 16 November 2017

2017-11-16T12:03:34Z

←Older revision		Revision as of 12:03, 16 November 2017
Line 16:		Line 16:
	</div>		</div>
	<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[DNA polymerase\|DNA polymerase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 08:06, 3 August 2017

2017-08-03T08:06:24Z

←Older revision		Revision as of 08:06, 3 August 2017
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	<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure ~~with sequence from [http://en.wikipedia.org/wiki/Nosp7 Nosp7]~~. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [http://pdbe.org/4kl6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [http://pdbe.org/4kl6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Nosp7]]
	[[Category: Aranko, A S]]		[[Category: Aranko, A S]]
	[[Category: Iwai, H]]		[[Category: Iwai, H]]

OCA at 19:05, 4 August 2016

2016-08-04T19:05:46Z

←Older revision		Revision as of 19:05, 4 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of dimeric form of NpuDnaE intein==		==Crystal structure of dimeric form of NpuDnaE intein==
	<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/~~Nostoc_punctiforme_pcc_73102 Nostoc punctiforme pcc 73102~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Nosp7 Nosp7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4kl6 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [http://pdbe.org/4kl6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4kl6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4kl6 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4kl6" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Nostoc punctiforme pcc 73102~~]]	+	[[Category: Nosp7]]
	[[Category: Aranko, A S]]		[[Category: Aranko, A S]]
	[[Category: Iwai, H]]		[[Category: Iwai, H]]

OCA at 12:14, 25 December 2014

2014-12-25T12:14:09Z

←Older revision		Revision as of 12:14, 25 December 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4kl6\| PDB=4kl6 \| SCENE= }}~~	+	==Crystal structure of dimeric form of NpuDnaE intein==
-	===Crystal structure of dimeric form of NpuDnaE intein===	+	<StructureSection load='4kl6' size='340' side='right' caption='[[4kl6]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~{{ABSTRACT_PUBMED_23974115}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4kl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Nostoc_punctiforme_pcc_73102 Nostoc punctiforme pcc 73102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4KL6 FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2keq\|2keq]], [[4kl5\|4kl5]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4kl6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4kl6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4kl6 RCSB], [http://www.ebi.ac.uk/pdbsum/4kl6 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Protein sequences are diversified on the DNA level by recombination and mutation and can be further increased on the RNA level by alternative RNA splicing, involving introns that have important roles in many biological processes. The protein version of introns (inteins), which catalyze protein splicing, were first reported in the 1990s. The biological roles of protein splicing still remain elusive because inteins neither provide any clear benefits nor have an essential role in their host organisms. We now report protein alternative splicing, in which new protein sequences can be produced by protein recombination by intermolecular domain swapping of inteins, as elucidated by NMR spectroscopy and crystal structures. We demonstrate that intein-mediated protein alternative splicing could be a new strategy to increase protein diversity (that is, functions) without any modification in genetic backgrounds. We also exploited it as a post-translational protein conformation-driven switch of protein functions (for example, as highly specific protein interference).

-	~~==About this Structure==~~	+	Intermolecular domain swapping induces intein-mediated protein alternative splicing.,Aranko AS, Oeemig JS, Kajander T, Iwai H Nat Chem Biol. 2013 Aug 25. doi: 10.1038/nchembio.1320. PMID:23974115<ref>PMID:23974115</ref>
-	~~[[4kl6]] is a 4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Nostoc_punctiforme_pcc_73102 Nostoc punctiforme pcc 73102]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann~~.~~ac.il~~/~~oca-bin/ocashort?id=4KL6 OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group~~=~~"xtra">PMID:023974115</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
		+
		+	==See Also==
		+	*[[DNA polymerase\|DNA polymerase]]
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Nostoc punctiforme pcc 73102]]		[[Category: Nostoc punctiforme pcc 73102]]
-	[[Category: Aranko, A S.]]	+	[[Category: Aranko, A S]]
-	[[Category: Iwai, H.]]	+	[[Category: Iwai, H]]
-	[[Category: Kajander, T.]]	+	[[Category: Kajander, T]]
-	[[Category: Oeemig, J S.]]	+	[[Category: Oeemig, J S]]
	[[Category: Domain swapped]]		[[Category: Domain swapped]]
	[[Category: Hint]]		[[Category: Hint]]

OCA at 10:42, 4 September 2013

2013-09-04T10:42:59Z

←Older revision		Revision as of 10:42, 4 September 2013
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4kl6\| PDB=4kl6 \| SCENE= }}
		+	===Crystal structure of dimeric form of NpuDnaE intein===
		+	{{ABSTRACT_PUBMED_23974115}}

-	~~The entry~~ 4kl6 is ~~ON HOLD~~	+	==About this Structure==
		+	[[4kl6]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Nostoc_punctiforme_pcc_73102 Nostoc punctiforme pcc 73102]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KL6 OCA].

-	~~Authors~~: Aranko, A.S., ~~Oeemig, J~~.~~S.,~~ Kajander, T., ~~Iwai, H~~.	+	==Reference==
-		+	<ref group="xtra">PMID:023974115</ref><references group="xtra"/><references/>
-	~~Description~~: ~~Crystal structure of dimeric form of NpuDnaE intein~~	+	[[Category: Nostoc punctiforme pcc 73102]]
		+	[[Category: Aranko, A S.]]
		+	[[Category: Iwai, H.]]
		+	[[Category: Kajander, T.]]
		+	[[Category: Oeemig, J S.]]
		+	[[Category: Domain swapped]]
		+	[[Category: Hint]]
		+	[[Category: Intein]]
		+	[[Category: Npudnae inten]]
		+	[[Category: Unknown function]]

OCA at 11:42, 19 June 2013

2013-06-19T11:42:44Z

←Older revision		Revision as of 11:42, 19 June 2013
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4kl6 is ON HOLD ~~until sometime in the future~~	+	The entry 4kl6 is ON HOLD

	Authors: Aranko, A.S., Oeemig, J.S., Kajander, T., Iwai, H.		Authors: Aranko, A.S., Oeemig, J.S., Kajander, T., Iwai, H.

	Description: Crystal structure of dimeric form of NpuDnaE intein		Description: Crystal structure of dimeric form of NpuDnaE intein

OCA: Protected "4kl6" [edit=sysop:move=sysop]

2013-05-16T06:58:36Z

Protected "4kl6" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:58, 16 May 2013