4lug - Revision history

OCA at 14:38, 8 November 2023

2023-11-08T14:38:11Z

←Older revision		Revision as of 14:38, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.93Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [https://pdbe.org/4lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [https://www.ebi.ac.uk/pdbsum/4lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [https://pdbe.org/4lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [https://www.ebi.ac.uk/pdbsum/4lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>
	</table>		</table>

OCA at 10:32, 21 December 2022

2022-12-21T10:32:37Z

←Older revision		Revision as of 10:32, 21 December 2022
Line 3:		Line 3:
	<StructureSection load='4lug' size='340' side='right'caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='4lug' size='340' side='right'caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arath Arath~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4LUG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LUG FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [https://pdbe.org/4lug PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [https://www.ebi.ac.uk/pdbsum/4lug PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PPa1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [~~http~~://pdbe.org/4lug PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4lug PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>	+
	</table>		</table>
-	~~<div style~~=~~"background-color:#fffaf0;">~~	+	== Function ==
-	=~~= Publication Abstract from PubMed~~ ==	+	[https://www.uniprot.org/uniprot/IPYR1_ARATH IPYR1_ARATH] Catalyzes the irreversible hydrolysis of pyrophosphate (PPi) to phosphate. The MgPPi(2-) complex binds to the enzyme only after a free Mg(2+) ion has bound (Ref.9). No activity with glycerol-3-phosphate, glucose-6-phosphate, p-nitrophenylphosphate, ADP, NADP(+), NAD(+),NADH, NADPH or phosphoribosyl pyrophosphate as substrates (Ref.9). Controls the equilibrium of gluconeogenic reactions in the heterotrophic growth phase of early seedling establishment. Determinates the rate of cytosolic glycolysis, providing carbon for seed storage lipid accumulation (PubMed:22566496).<ref>PMID:22566496</ref> [REFERENCE:9]
-	~~An Arabidopsis cDNA coding for a previously uncharacterized isoform~~ of ~~inorganic pyrophosphatase was isolated~~. ~~It was used~~ to ~~complement an E. coli mutant, demonstrating that it coded for an active~~ enzyme~~. MgCl~~(2) ~~was necessary for the protein's~~ activity, ~~whilst NaF inhibited it. The K~~(m) ~~for~~ pyrophosphate ~~and~~ the ~~pH optimum~~ of the ~~protein was determined~~. ~~The gene coding for this protein was expressed in all tissues, and its expression in rosette leaves was induced by incubation on metabolizable sugars. In vitro import experiments demonstrated that~~ the ~~protein could be imported into chloroplasts and localized to the stromal compartment.~~	+
-		+
-	~~Identification~~ of ~~an Arabidopsis inorganic pyrophosphatase capable of being imported into chloroplasts.~~,~~Schulze S, Mant A, Kossmann J, Lloyd JR FEBS Lett. 2004 May 7;565~~(~~1-3~~)~~:101-5~~. ~~PMID:15135060~~<ref>PMID:~~15135060~~</ref>	+
-		+
-	~~From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>~~	+
-	~~</div>~~	+
-	~~<div class="pdbe-citations 4lug" style="background-color~~:~~#fffaf0;"></div>~~	+

	==See Also==		==See Also==
-	*[[Inorganic pyrophosphatase\|Inorganic pyrophosphatase]]	+	*[[Inorganic pyrophosphatase 3D structures\|Inorganic pyrophosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arath]]~~	+	[[Category: Arabidopsis thaliana]]
-	~~[[Category: Inorganic diphosphatase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Grzechowiak, M]]	+	[[Category: Grzechowiak M]]
-	[[Category: Jaskolski, M]]	+	[[Category: Jaskolski M]]
-	[[Category: Ruszkowski, M]]	+	[[Category: Ruszkowski M]]
-	[[Category: Sikorski, M]]	+	[[Category: Sikorski M]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolysis of pyrophosphate]]~~	+
-	~~[[Category: Magnesium ion binding]]~~	+
-	~~[[Category: Metal binding~~]]	+

OCA at 08:51, 3 April 2019

2019-04-03T08:51:11Z

←Older revision		Revision as of 08:51, 3 April 2019
Line 1:		Line 1:

	==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana==		==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana==
-	<StructureSection load='4lug' size='340' side='right' caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>	+	<StructureSection load='4lug' size='340' side='right'caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LUG FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Arath Arath]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LUG FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PPa1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3702 ARATH])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://pdbe.org/4lug PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://pdbe.org/4lug PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>
Line 25:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arath]]
	[[Category: Inorganic diphosphatase]]		[[Category: Inorganic diphosphatase]]
		+	[[Category: Large Structures]]
	[[Category: Grzechowiak, M]]		[[Category: Grzechowiak, M]]
	[[Category: Jaskolski, M]]		[[Category: Jaskolski, M]]

OCA at 09:10, 11 August 2016

2016-08-11T09:10:57Z

←Older revision		Revision as of 09:10, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana==		==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana==
	<StructureSection load='4lug' size='340' side='right' caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>		<StructureSection load='4lug' size='340' side='right' caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://pdbe.org/4lug PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4lug ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4lug" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Inorganic pyrophosphatase\|Inorganic pyrophosphatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:36, 5 January 2015

2015-01-05T12:36:24Z

←Older revision		Revision as of 12:36, 5 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LUG FirstGlance]. <br>		<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LUG FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	</StructureSection>		</StructureSection>
	[[Category: Inorganic diphosphatase]]		[[Category: Inorganic diphosphatase]]
-	[[Category: Grzechowiak, M.]]	+	[[Category: Grzechowiak, M]]
-	[[Category: Jaskolski, M.]]	+	[[Category: Jaskolski, M]]
-	[[Category: Ruszkowski, M.]]	+	[[Category: Ruszkowski, M]]
-	[[Category: Sikorski, M.]]	+	[[Category: Sikorski, M]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Hydrolysis of pyrophosphate]]		[[Category: Hydrolysis of pyrophosphate]]
	[[Category: Magnesium ion binding]]		[[Category: Magnesium ion binding]]
	[[Category: Metal binding]]		[[Category: Metal binding]]

OCA at 07:32, 30 July 2014

2014-07-30T07:32:33Z

←Older revision		Revision as of 07:32, 30 July 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana==
		+	<StructureSection load='4lug' size='340' side='right' caption='[[4lug]], [[Resolution\|resolution]] 1.93Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4lug]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LUG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LUG FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3emj\|3emj]], [[3tr4\|3tr4]], [[3i4q\|3i4q]], [[1ygz\|1ygz]], [[3fq3\|3fq3]], [[1twl\|1twl]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Inorganic_diphosphatase Inorganic diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.1 3.6.1.1] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lug FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lug OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lug RCSB], [http://www.ebi.ac.uk/pdbsum/4lug PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	An Arabidopsis cDNA coding for a previously uncharacterized isoform of inorganic pyrophosphatase was isolated. It was used to complement an E. coli mutant, demonstrating that it coded for an active enzyme. MgCl(2) was necessary for the protein's activity, whilst NaF inhibited it. The K(m) for pyrophosphate and the pH optimum of the protein was determined. The gene coding for this protein was expressed in all tissues, and its expression in rosette leaves was induced by incubation on metabolizable sugars. In vitro import experiments demonstrated that the protein could be imported into chloroplasts and localized to the stromal compartment.

-	~~The entry 4lug is ON HOLD until Paper Publication~~	+	Identification of an Arabidopsis inorganic pyrophosphatase capable of being imported into chloroplasts.,Schulze S, Mant A, Kossmann J, Lloyd JR FEBS Lett. 2004 May 7;565(1-3):101-5. PMID:15135060<ref>PMID:15135060</ref>

-	~~Authors~~: Grzechowiak, M., Ruszkowski, M., Sikorski, M.~~, Jaskolski, M.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure~~ of ~~Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Inorganic diphosphatase]]
		+	[[Category: Grzechowiak, M.]]
		+	[[Category: Jaskolski, M.]]
		+	[[Category: Ruszkowski, M.]]
		+	[[Category: Sikorski, M.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolysis of pyrophosphate]]
		+	[[Category: Magnesium ion binding]]
		+	[[Category: Metal binding]]

OCA at 07:19, 14 August 2013

2013-08-14T07:19:42Z

←Older revision		Revision as of 07:19, 14 August 2013
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4lug is ON HOLD	+	The entry 4lug is ON HOLD until Paper Publication

	Authors: Grzechowiak, M., Ruszkowski, M., Sikorski, M., Jaskolski, M.		Authors: Grzechowiak, M., Ruszkowski, M., Sikorski, M., Jaskolski, M.

	Description: Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana		Description: Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana

OCA: Protected "4lug" [edit=sysop:move=sysop]

2013-08-01T04:25:07Z

Protected "4lug" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:25, 1 August 2013

OCA: New page: '''Unreleased structure''' The entry 4lug is ON HOLD Authors: Grzechowiak, M., Ruszkowski, M., Sikorski, M., Jaskolski, M. Description: Crystal structure of Inorganic Pyrophosphatase P...

2013-08-01T04:25:05Z

New page: '''Unreleased structure''' The entry 4lug is ON HOLD Authors: Grzechowiak, M., Ruszkowski, M., Sikorski, M., Jaskolski, M. Description: Crystal structure of Inorganic Pyrophosphatase P...

New page

'''Unreleased structure'''

The entry 4lug is ON HOLD

Authors: Grzechowiak, M., Ruszkowski, M., Sikorski, M., Jaskolski, M.

Description: Crystal structure of Inorganic Pyrophosphatase PPA1 from Arabidopsis thaliana