4mkj - Revision history

OCA at 16:38, 20 September 2023

2023-09-20T16:38:44Z

←Older revision		Revision as of 16:38, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.849Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [https://pdbe.org/4mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [https://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [https://pdbe.org/4mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [https://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>
	</table>		</table>

OCA at 09:43, 28 December 2022

2022-12-28T09:43:43Z

←Older revision		Revision as of 09:43, 28 December 2022
Line 3:		Line 3:
	<StructureSection load='4mkj' size='340' side='right'caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='4mkj' size='340' side='right'caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"bacterium_freundii"_braak_1928 "bacterium~~ freundii~~" braak 1928~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Citrobacter_freundii Citrobacter freundii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, ~~<scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene><~~/td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [https://pdbe.org/4mkj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [https://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>
-	~~<tr id~~='~~related'><td class~~=~~"sblockLbl"><b>[[Related_structure\|Related~~:~~]]</b~~></td>~~<td class="sblockDat">[[2rfv\|2rfv]]~~, ~~[[4mkk\|4mkk]]~~<~~/td></tr>~~	+
-	~~<tr id~~='~~gene'><td class~~=~~"sblockLbl"><b>[[Gene\|Gene~~:~~]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>~~	+
-	~~<tr id='activity~~'>~~<td class="sblockLbl"><b>Activity:~~</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [~~http~~://pdbe.org/4mkj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q84AR1_CITFR Q84AR1_CITFR]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 20:

	==See Also==		==See Also==
-	*[[Methionine gamma-lyase\|Methionine gamma-lyase]]	+	*[[Methionine gamma-lyase 3D structures\|Methionine gamma-lyase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bacterium~~ freundii ~~braak 1928~~]]	+	[[Category: Citrobacter freundii]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Methionine gamma-lyase]]~~	+	[[Category: Demidkina TV]]
-	[[Category: Demidkina~~, T V~~]]	+	[[Category: Morozova EA]]
-	[[Category: Morozova~~, E A~~]]	+	[[Category: Nikulin AD]]
-	[[Category: Nikulin~~, A D~~]]	+	[[Category: Revtovich SV]]
-	[[Category: Revtovich~~, S V~~]]	+	[[Category: Zakomirdina LN]]
-	[[Category: Zakomirdina~~, L N]]~~	+
-	~~[[Category: Allicine]]~~	+
-	~~[[Category: Aminotransferase class-v]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Plp-dependent enzyme]]~~	+
-	~~[[Category: Pyridoxal-5'-phosphate~~]]	+

OCA at 08:37, 10 April 2019

2019-04-10T08:37:00Z

←Older revision		Revision as of 08:37, 10 April 2019
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	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine==		==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine==
-	<StructureSection load='4mkj' size='340' side='right' caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='4mkj' size='340' side='right'caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacterium_freundii"_braak_1928 "bacterium freundii" braak 1928]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[4mkk\|4mkk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[4mkk\|4mkk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">megL ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=546 "Bacterium freundii" Braak 1928])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://pdbe.org/4mkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://pdbe.org/4mkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>
Line 26:		Line 27:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bacterium freundii braak 1928]]
		+	[[Category: Large Structures]]
	[[Category: Methionine gamma-lyase]]		[[Category: Methionine gamma-lyase]]
	[[Category: Demidkina, T V]]		[[Category: Demidkina, T V]]

OCA at 05:53, 5 August 2016

2016-08-05T05:53:24Z

←Older revision		Revision as of 05:53, 5 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine==		==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine==
	<StructureSection load='4mkj' size='340' side='right' caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='4mkj' size='340' side='right' caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:2-~~LYSINE(~~3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-~~YLMETHANE)~~'>LLP</scene></td></tr>	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:(2S)-2-AMINO-6-[[3-HYDROXY-2-METHYL-5-(PHOSPHONOOXYMETHYL)PYRIDIN-4-YL]METHYLIDENEAMINO]HEXANOIC+ACID'>LLP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[4mkk\|4mkk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[4mkk\|4mkk]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://pdbe.org/4mkj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mkj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4mkj" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Methionine gamma-lyase\|Methionine gamma-lyase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:37, 31 December 2014

2014-12-31T09:37:38Z

←Older revision		Revision as of 09:37, 31 December 2014
Line 9:		Line 9:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The interaction of Citrobacter freundii methionine gamma-lyase (MGL) and the mutant form in which Cys115 is replaced by Ala (MGL C115A) with the nonprotein amino acid (2R)-2-amino-3-[(S)-prop-2-enylsulfinyl]propanoic acid (alliin) was investigated. It was found that MGL catalyzes the beta-elimination reaction of alliin to form 2-propenethiosulfinate (allicin), pyruvate and ammonia. The beta-elimination reaction of alliin is followed by the inactivation and modification of SH groups of the wild-type and mutant enzymes. Three-dimensional structures of inactivated wild-type MGL (iMGL wild type) and a C115A mutant form (iMGL C115A) were determined at 1.85 and 1.45 A resolution and allowed the identification of the SH groups that were oxidized by allicin. On this basis, the mechanism of the inactivation of MGL by alliin, a new suicide substrate of MGL, is proposed.
		+
		+	Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme.,Morozova EA, Revtovich SV, Anufrieva NV, Kulikova VV, Nikulin AD, Demidkina TV Acta Crystallogr D Biol Crystallogr. 2014 Nov;70(Pt 11):3034-42. doi:, 10.1107/S1399004714020938. Epub 2014 Oct 29. PMID:25372692<ref>PMID:25372692</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:51, 12 November 2014

2014-11-12T06:51:05Z

←Older revision		Revision as of 06:51, 12 November 2014
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-	'''~~Unreleased structure~~'''	+	==Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine==
-		+	<StructureSection load='4mkj' size='340' side='right' caption='[[4mkj]], [[Resolution\|resolution]] 1.85Å' scene=''>
-	~~The entry~~ 4mkj is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4mkj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MKJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MKJ FirstGlance]. <br>
-	~~Authors~~: ~~Revtovich~~, S.V., ~~Nikulin, A~~.D., ~~Morozova, E~~.A., ~~Zakomirdina, L~~.N., Demidkina, T.V.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=C1S:3-(PROP-2-EN-1-YLDISULFANYL)-L-ALANINE'>C1S</scene>, <scene name='pdbligand=LLP:2-LYSINE(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHANE)'>LLP</scene></td></tr>
-	~~Description~~: ~~Crystal structure of~~ L-~~methionine gamma~~-~~lyase from Citrobacter freundii modified by allicine~~	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2rfv\|2rfv]], [[4mkk\|4mkk]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_gamma-lyase Methionine gamma-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.4.1.11 4.4.1.11] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mkj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mkj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mkj RCSB], [http://www.ebi.ac.uk/pdbsum/4mkj PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Methionine gamma-lyase]]
		+	[[Category: Demidkina, T V]]
		+	[[Category: Morozova, E A]]
		+	[[Category: Nikulin, A D]]
		+	[[Category: Revtovich, S V]]
		+	[[Category: Zakomirdina, L N]]
		+	[[Category: Allicine]]
		+	[[Category: Aminotransferase class-v]]
		+	[[Category: Lyase]]
		+	[[Category: Plp-dependent enzyme]]
		+	[[Category: Pyridoxal-5'-phosphate]]

OCA at 07:44, 24 September 2014

2014-09-24T07:44:11Z

←Older revision		Revision as of 07:44, 24 September 2014
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4mkj is ON HOLD	+	The entry 4mkj is ON HOLD until Paper Publication

	Authors: Revtovich, S.V., Nikulin, A.D., Morozova, E.A., Zakomirdina, L.N., Demidkina, T.V.		Authors: Revtovich, S.V., Nikulin, A.D., Morozova, E.A., Zakomirdina, L.N., Demidkina, T.V.

	Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine		Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine

OCA: Protected "4mkj" [edit=sysop:move=sysop]

2013-09-12T04:54:42Z

Protected "4mkj" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:54, 12 September 2013

OCA: New page: '''Unreleased structure''' The entry 4mkj is ON HOLD Authors: Revtovich, S.V., Nikulin, A.D., Morozova, E.A., Zakomirdina, L.N., Demidkina, T.V. Description: Crystal structure of L-met...

2013-09-12T04:54:40Z

New page: '''Unreleased structure''' The entry 4mkj is ON HOLD Authors: Revtovich, S.V., Nikulin, A.D., Morozova, E.A., Zakomirdina, L.N., Demidkina, T.V. Description: Crystal structure of L-met...

New page

'''Unreleased structure'''

The entry 4mkj is ON HOLD

Authors: Revtovich, S.V., Nikulin, A.D., Morozova, E.A., Zakomirdina, L.N., Demidkina, T.V.

Description: Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine