4mvq - Revision history

OCA at 12:29, 1 March 2024

2024-03-01T12:29:45Z

←Older revision		Revision as of 12:29, 1 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliarcobacter_butzleri_RM4018 Aliarcobacter butzleri RM4018]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliarcobacter_butzleri_RM4018 Aliarcobacter butzleri RM4018]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [https://pdbe.org/4mvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [https://www.ebi.ac.uk/pdbsum/4mvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvq ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [https://pdbe.org/4mvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [https://www.ebi.ac.uk/pdbsum/4mvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/A8EVM5_ALIB4 A8EVM5_ALIB4]		[https://www.uniprot.org/uniprot/A8EVM5_ALIB4 A8EVM5_ALIB4]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. How CaV channels solve this fundamental biophysical problem remains unclear. Here we report physiological and crystallographic analyses of a calcium selectivity filter constructed in the homotetrameric bacterial NaV channel NaVAb. Our results reveal interactions of hydrated Ca2+ with two high-affinity Ca2+-binding sites followed by a third lower-affinity site that would coordinate Ca2+ as it moves inward. At the selectivity filter entry, Site 1 is formed by four carboxyl side chains, which have a critical role in determining Ca2+ selectivity. Four carboxyls plus four backbone carbonyls form Site 2, which is targeted by the blocking cations Cd2+ and Mn2+, with single occupancy. The lower-affinity Site 3 is formed by four backbone carbonyls alone, which mediate exit into the central cavity. This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca2+ ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwise-binding process. The multi-ion selectivity filter of our CaVAb model establishes a structural framework for understanding the mechanisms of ion selectivity and conductance by vertebrate CaV channels.
-
-	Structural basis for Ca selectivity of a voltage-gated calcium channel.,Tang L, Gamal El-Din TM, Payandeh J, Martinez GQ, Heard TM, Scheuer T, Zheng N, Catterall WA Nature. 2013 Nov 24. doi: 10.1038/nature12775. PMID:24270805<ref>PMID:24270805</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 4mvq" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 10:12, 28 December 2022

2022-12-28T10:12:56Z

←Older revision		Revision as of 10:12, 28 December 2022
Line 1:		Line 1:

	==Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel==		==Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel==
-	<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='4mvq' size='340' side='right'caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Arcb4 Arcb4~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliarcobacter_butzleri_RM4018 Aliarcobacter butzleri RM4018]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [https://pdbe.org/4mvq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [https://www.ebi.ac.uk/pdbsum/4mvq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvq ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Abu_1752 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367737 ARCB4])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [~~http~~://pdbe.org/4mvq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4mvq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvq ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A8EVM5_ALIB4 A8EVM5_ALIB4]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Arcb4~~]]	+	[[Category: Aliarcobacter butzleri RM4018]]
-	[[Category: Catterall~~, W A~~]]	+	[[Category: Large Structures]]
-	[[Category: El-Din~~, T M.Gamal~~]]	+	[[Category: Catterall WA]]
-	[[Category: Gilbert~~, Q M~~]]	+	[[Category: Gamal El-Din TM]]
-	[[Category: Heard~~, T M~~]]	+	[[Category: Gilbert QM]]
-	[[Category: Payandeh, J]]	+	[[Category: Heard TM]]
-	[[Category: Scheuer, T]]	+	[[Category: Payandeh J]]
-	[[Category: Tang, L]]	+	[[Category: Scheuer T]]
-	[[Category: Zheng, N]]	+	[[Category: Tang L]]
-	~~[[Category: Calcium selective]]~~	+	[[Category: Zheng N]]
-	~~[[Category: Membrane]]~~	+
-	~~[[Category: Metal transport]]~~	+
-	~~[[Category: Tetrameric]]~~	+
-	~~[[Category: Transport protein]]~~	+
-	~~[[Category: Voltage-gated calcium channel]]~~	+
-	~~[[Category: Voltage-gated ion channel~~]]	+

OCA at 16:44, 11 August 2016

2016-08-11T16:44:28Z

←Older revision		Revision as of 16:44, 11 August 2016
Line 1:		Line 1:
		+
	==Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel==		==Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel==
	<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Abu_1752 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367737 ARCB4])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Abu_1752 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367737 ARCB4])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [http://www.ebi.ac.uk/pdbsum/4mvq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [http://pdbe.org/4mvq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [http://www.ebi.ac.uk/pdbsum/4mvq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4mvq ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4mvq" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:47, 25 January 2015

2015-01-25T10:47:34Z

←Older revision		Revision as of 10:47, 25 January 2015
Line 2:		Line 2:
	<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcb4 Arcb4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Abu_1752 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=367737 ARCB4])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [http://www.ebi.ac.uk/pdbsum/4mvq PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [http://www.ebi.ac.uk/pdbsum/4mvq PDBsum]</span></td></tr>
	</table>		</table>
Line 19:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Arcb4]]
	[[Category: Catterall, W A]]		[[Category: Catterall, W A]]
	[[Category: El-Din, T M.Gamal]]		[[Category: El-Din, T M.Gamal]]

OCA at 07:40, 12 November 2014

2014-11-12T07:40:35Z

←Older revision		Revision as of 07:40, 12 November 2014
Line 1:		Line 1:
-	~~{{STRUCTURE_4mvq\| PDB=4mvq \| SCENE= }}~~	+	==Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel==
-	===Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel===	+	<StructureSection load='4mvq' size='340' side='right' caption='[[4mvq]], [[Resolution\|resolution]] 3.40Å' scene=''>
-	~~{{ABSTRACT_PUBMED_24270805}}~~	+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4mvq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4MVQ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=PX4:1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHOCHOLINE'>PX4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ms2\|4ms2]], [[4mtf\|4mtf]], [[4mtg\|4mtg]], [[4mto\|4mto]], [[4mvm\|4mvm]], [[4mvo\|4mvo]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4mvq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4mvq OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4mvq RCSB], [http://www.ebi.ac.uk/pdbsum/4mvq PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Voltage-gated calcium (CaV) channels catalyse rapid, highly selective influx of Ca2+ into cells despite a 70-fold higher extracellular concentration of Na+. How CaV channels solve this fundamental biophysical problem remains unclear. Here we report physiological and crystallographic analyses of a calcium selectivity filter constructed in the homotetrameric bacterial NaV channel NaVAb. Our results reveal interactions of hydrated Ca2+ with two high-affinity Ca2+-binding sites followed by a third lower-affinity site that would coordinate Ca2+ as it moves inward. At the selectivity filter entry, Site 1 is formed by four carboxyl side chains, which have a critical role in determining Ca2+ selectivity. Four carboxyls plus four backbone carbonyls form Site 2, which is targeted by the blocking cations Cd2+ and Mn2+, with single occupancy. The lower-affinity Site 3 is formed by four backbone carbonyls alone, which mediate exit into the central cavity. This pore architecture suggests a conduction pathway involving transitions between two main states with one or two hydrated Ca2+ ions bound in the selectivity filter and supports a 'knock-off' mechanism of ion permeation through a stepwise-binding process. The multi-ion selectivity filter of our CaVAb model establishes a structural framework for understanding the mechanisms of ion selectivity and conductance by vertebrate CaV channels.

-	~~==About this Structure==~~	+	Structural basis for Ca selectivity of a voltage-gated calcium channel.,Tang L, Gamal El-Din TM, Payandeh J, Martinez GQ, Heard TM, Scheuer T, Zheng N, Catterall WA Nature. 2013 Nov 24. doi: 10.1038/nature12775. PMID:24270805<ref>PMID:24270805</ref>
-	~~[[4mvq]] is~~ a ~~4 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arcb4 Arcb4]~~. ~~Full crystallographic information is available from [http~~:/~~/oca~~.~~weizmann.ac.il~~/~~oca-bin/ocashort?id=4MVQ OCA].~~	+

-	==~~Reference~~==	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~<ref group="xtra">PMID:024270805</ref>~~<references ~~group="xtra"~~/><~~references~~/>	+	</div>
-	~~[[Category: Arcb4]]~~	+	== References ==
-	[[Category: Catterall, W A.]]	+	<references/>
-	[[Category: El-Din, T M.Gamal.]]	+	__TOC__
-	[[Category: Gilbert, Q M.]]	+	</StructureSection>
		+	[[Category: Catterall, W A]]
		+	[[Category: El-Din, T M.Gamal]]
		+	[[Category: Gilbert, Q M]]
	[[Category: Heard, T M]]		[[Category: Heard, T M]]
-	[[Category: Payandeh, J.]]	+	[[Category: Payandeh, J]]
-	[[Category: Scheuer, T.]]	+	[[Category: Scheuer, T]]
-	[[Category: Tang, L.]]	+	[[Category: Tang, L]]
-	[[Category: Zheng, N.]]	+	[[Category: Zheng, N]]
	[[Category: Calcium selective]]		[[Category: Calcium selective]]
	[[Category: Membrane]]		[[Category: Membrane]]

OCA at 08:30, 18 December 2013

2013-12-18T08:30:54Z

←Older revision		Revision as of 08:30, 18 December 2013
Line 1:		Line 1:
	{{STRUCTURE_4mvq\| PDB=4mvq \| SCENE= }}		{{STRUCTURE_4mvq\| PDB=4mvq \| SCENE= }}
	===Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel===		===Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel===
		+	{{ABSTRACT_PUBMED_24270805}}

	==About this Structure==		==About this Structure==
-	[[4mvq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA].	+	[[4mvq]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Arcb4 Arcb4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA].
		+
		+	==Reference==
		+	<ref group="xtra">PMID:024270805</ref><references group="xtra"/><references/>
		+	[[Category: Arcb4]]
	[[Category: Catterall, W A.]]		[[Category: Catterall, W A.]]
	[[Category: El-Din, T M.Gamal.]]		[[Category: El-Din, T M.Gamal.]]

OCA at 10:35, 27 November 2013

2013-11-27T10:35:57Z

←Older revision		Revision as of 10:35, 27 November 2013
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	{{STRUCTURE_4mvq\| PDB=4mvq \| SCENE= }}
		+	===Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel===

-	~~The entry~~ 4mvq is ~~ON HOLD~~	+	==About this Structure==
-		+	[[4mvq]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4MVQ OCA].
-	~~Authors~~: ~~Tang~~, L.~~, Gamal~~ El-Din, T.M.~~, Payandeh, J~~., Gilbert, Q.M., Heard, T.M, Scheuer, T., ~~Ning, Z~~., ~~William, A.C~~.	+	[[Category: Catterall, W A.]]
-		+	[[Category: El-Din, T M.Gamal.]]
-	~~Description~~: ~~Structural Basis for Ca2+ Selectivity of a~~ Voltage-gated ~~Calcium Channel~~	+	[[Category: Gilbert, Q M.]]
		+	[[Category: Heard, T M]]
		+	[[Category: Payandeh, J.]]
		+	[[Category: Scheuer, T.]]
		+	[[Category: Tang, L.]]
		+	[[Category: Zheng, N.]]
		+	[[Category: Calcium selective]]
		+	[[Category: Membrane]]
		+	[[Category: Metal transport]]
		+	[[Category: Tetrameric]]
		+	[[Category: Transport protein]]
		+	[[Category: Voltage-gated calcium channel]]
		+	[[Category: Voltage-gated ion channel]]

OCA: Protected "4mvq" [edit=sysop:move=sysop]

2013-10-02T06:56:21Z

Protected "4mvq" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:56, 2 October 2013

OCA: New page: '''Unreleased structure''' The entry 4mvq is ON HOLD Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Gilbert, Q.M., Heard, T.M, Scheuer, T., Ning, Z., William, A.C. Description: S...

2013-10-02T06:56:20Z

New page: '''Unreleased structure''' The entry 4mvq is ON HOLD Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Gilbert, Q.M., Heard, T.M, Scheuer, T., Ning, Z., William, A.C. Description: S...

New page

'''Unreleased structure'''

The entry 4mvq is ON HOLD

Authors: Tang, L., Gamal El-Din, T.M., Payandeh, J., Gilbert, Q.M., Heard, T.M, Scheuer, T., Ning, Z., William, A.C.

Description: Structural Basis for Ca2+ Selectivity of a Voltage-gated Calcium Channel