4nnl - Revision history

OCA at 17:00, 20 September 2023

2023-09-20T17:00:28Z

←Older revision		Revision as of 17:00, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [https://pdbe.org/4nnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [https://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [https://pdbe.org/4nnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [https://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 08:36, 11 January 2023

2023-01-11T08:36:25Z

←Older revision		Revision as of 08:36, 11 January 2023
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	<StructureSection load='4nnl' size='340' side='right'caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='4nnl' size='340' side='right'caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4NNL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [https://pdbe.org/4nnl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [https://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TAX1BP3, TIP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [~~http~~://pdbe.org/4nnl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN]] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>	+	[https://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Amacher~~, J F~~]]	+	[[Category: Amacher JF]]
-	[[Category: Madden~~, D R]]~~	+	[[Category: Madden DR]]
-	~~[[Category: Pdz]]~~	+
-	~~[[Category: Pdz-peptide]]~~	+
-	~~[[Category: Protein binding]]~~	+
-	~~[[Category: Tax-interacting protein-1]]~~	+
-	~~[[Category: Tip-1~~]]	+

OCA at 08:54, 10 April 2019

2019-04-10T08:54:22Z

←Older revision		Revision as of 08:54, 10 April 2019
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	==Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide==		==Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide==
-	<StructureSection load='4nnl' size='340' side='right' caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='4nnl' size='340' side='right'caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TAX1BP3, TIP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://pdbe.org/4nnl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://pdbe.org/4nnl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
	</table>		</table>
Line 13:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Amacher, J F]]		[[Category: Amacher, J F]]
	[[Category: Madden, D R]]		[[Category: Madden, D R]]

OCA at 07:54, 11 August 2016

2016-08-11T07:54:26Z

←Older revision		Revision as of 07:54, 11 August 2016
Line 1:		Line 1:
		+
	==Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide==		==Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide==
	<StructureSection load='4nnl' size='340' side='right' caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>		<StructureSection load='4nnl' size='340' side='right' caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://pdbe.org/4nnl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nnl ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 16:56, 21 January 2015

2015-01-21T16:56:42Z

←Older revision		Revision as of 16:56, 21 January 2015
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	==Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide==
-		+	<StructureSection load='4nnl' size='340' side='right' caption='[[4nnl]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~The entry 4nnl is ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4nnl]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NNL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NNL FirstGlance]. <br>
-	~~Authors: Amacher, J.F., Madden, D.R.~~	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3sfj\|3sfj]], [[4nnm\|4nnm]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nnl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nnl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nnl RCSB], [http://www.ebi.ac.uk/pdbsum/4nnl PDBsum]</span></td></tr>
-	~~Description:~~ Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide	+	</table>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	== Function ==
-	[[Category: Amacher, J.F]]	+	[[http://www.uniprot.org/uniprot/TX1B3_HUMAN TX1B3_HUMAN]] May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6.<ref>PMID:10940294</ref> <ref>PMID:16855024</ref> <ref>PMID:21139582</ref>
-	[[Category: Madden, D.R]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Amacher, J F]]
		+	[[Category: Madden, D R]]
		+	[[Category: Pdz]]
		+	[[Category: Pdz-peptide]]
		+	[[Category: Protein binding]]
		+	[[Category: Tax-interacting protein-1]]
		+	[[Category: Tip-1]]

OCA at 14:13, 24 December 2014

2014-12-24T14:13:17Z

←Older revision		Revision as of 14:13, 24 December 2014
Line 6:		Line 6:

	Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide		Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide
		+	[[Category: Unreleased Structures]]
		+	[[Category: Amacher, J.F]]
		+	[[Category: Madden, D.R]]

OCA at 07:00, 29 January 2014

2014-01-29T07:00:33Z

←Older revision		Revision as of 07:00, 29 January 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4nnl is ON HOLD	+	The entry 4nnl is ON HOLD until Paper Publication

	Authors: Amacher, J.F., Madden, D.R.		Authors: Amacher, J.F., Madden, D.R.

	Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide		Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide

OCA: Protected "4nnl" [edit=sysop:move=sysop]

2013-11-27T09:52:28Z

Protected "4nnl" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:52, 27 November 2013

OCA: New page: '''Unreleased structure''' The entry 4nnl is ON HOLD Authors: Amacher, J.F., Madden, D.R. Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) pepti...

2013-11-27T09:52:27Z

New page: '''Unreleased structure''' The entry 4nnl is ON HOLD Authors: Amacher, J.F., Madden, D.R. Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) pepti...

New page

'''Unreleased structure'''

The entry 4nnl is ON HOLD

Authors: Amacher, J.F., Madden, D.R.

Description: Tax-Interacting Protein-1 (TIP-1) PDZ domain bound to F-iCAL36 (ANSRFPTSII) peptide