4nt4 - Revision history

OCA at 14:49, 8 November 2023

2023-11-08T14:49:50Z

←Older revision		Revision as of 14:49, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4nt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NT4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4nt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NT4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.86Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [https://pdbe.org/4nt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [https://www.ebi.ac.uk/pdbsum/4nt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nt4 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [https://pdbe.org/4nt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [https://www.ebi.ac.uk/pdbsum/4nt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nt4 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:38, 18 January 2023

2023-01-18T08:38:34Z

←Older revision		Revision as of 08:38, 18 January 2023
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	==Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster==		==Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster==
-	<StructureSection load='4nt4' size='340' side='right' caption='[[4nt4]], [[Resolution\|resolution]] 2.86Å' scene=''>	+	<StructureSection load='4nt4' size='340' side='right'caption='[[4nt4]], [[Resolution\|resolution]] 2.86Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4nt4]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Drome Drome~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4NT4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4nt4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4NT4 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG6963, Dmel_CG6963, gish ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [https://pdbe.org/4nt4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [https://www.ebi.ac.uk/pdbsum/4nt4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4nt4 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [~~http~~://pdbe.org/4nt4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4nt4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4nt4 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q86NK8_DROME Q86NK8_DROME]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Drome~~]]	+	[[Category: Drosophila melanogaster]]
-	[[Category: ~~Chen, C C~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Shi, Z B~~]]	+	[[Category: Chen CC]]
-	[[Category: ~~Zhou, Z C~~]]	+	[[Category: Shi ZB]]
-	[[Category: ~~Serine/threonine protein kinase]]~~	+	[[Category: Zhou ZC]]
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Wnt signaling pathway~~]]	+

OCA at 16:57, 2 January 2017

2017-01-02T16:57:32Z

←Older revision		Revision as of 16:57, 2 January 2017
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		+
	==Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster==		==Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster==
	<StructureSection load='4nt4' size='340' side='right' caption='[[4nt4]], [[Resolution\|resolution]] 2.86Å' scene=''>		<StructureSection load='4nt4' size='340' side='right' caption='[[4nt4]], [[Resolution\|resolution]] 2.86Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG6963, Dmel_CG6963, gish ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>		<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG6963, Dmel_CG6963, gish ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nt4 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [http://pdbe.org/4nt4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nt4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4nt4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4nt4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 05:57, 11 March 2015

2015-03-11T05:57:52Z

←Older revision		Revision as of 05:57, 11 March 2015
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nt4 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nt4 PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The CK1 family kinases regulate multiple cellular aspects and play important roles in Wnt/Wingless and Hedgehog signalling. The kinase domain of Drosophila Gilgamesh isoform I (Gilgamesh-I), a homologue of human CK1-gamma, was purified and crystallized. Crystals of methylated Gilgamesh-I kinase domain with a D210A mutation diffracted to 2.85 A resolution and belonged to space group P43212, with unit-cell parameters a = b = 52.025, c = 291.727 A. The structure of Gilgamesh-I kinase domain, which was determined by molecular replacement, has conserved catalytic elements and an active conformation. Structural comparison indicates that an extended loop between the alpha1 helix and the beta4 strand exists in the Gilgamesh-I kinase domain. This extended loop may regulate the activity and function of Gilgamesh-I.
		+
		+	Structure of the kinase domain of Gilgamesh from Drosophila melanogaster.,Han N, Chen C, Shi Z, Cheng D Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):438-43. doi:, 10.1107/S2053230X14004774. Epub 2014 Mar 25. PMID:24699734<ref>PMID:24699734</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:41, 5 January 2015

2015-01-05T09:41:31Z

←Older revision		Revision as of 09:41, 5 January 2015
Line 1:		Line 1:
-	~~{{STRUCTURE_4nt4\| PDB=4nt4 \| SCENE= }}~~	+	==Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster==
-	===Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster===	+	<StructureSection load='4nt4' size='340' side='right' caption='[[4nt4]], [[Resolution\|resolution]] 2.86Å' scene=''>
-		+	== Structural highlights ==
-	==~~About this Structure~~==	+	<table><tr><td colspan='2'>[[4nt4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4NT4 FirstGlance]. <br>
-	[[4nt4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA].	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: Chen, C C.]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">CG6963, Dmel_CG6963, gish ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
-	[[Category: Shi, Z B.]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4nt4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4nt4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4nt4 RCSB], [http://www.ebi.ac.uk/pdbsum/4nt4 PDBsum]</span></td></tr>
-	[[Category: Zhou, Z C.]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Drome]]
		+	[[Category: Chen, C C]]
		+	[[Category: Shi, Z B]]
		+	[[Category: Zhou, Z C]]
	[[Category: Serine/threonine protein kinase]]		[[Category: Serine/threonine protein kinase]]
	[[Category: Transferase]]		[[Category: Transferase]]
	[[Category: Wnt signaling pathway]]		[[Category: Wnt signaling pathway]]

OCA at 06:45, 9 April 2014

2014-04-09T06:45:24Z

←Older revision		Revision as of 06:45, 9 April 2014
Line 1:		Line 1:
-	~~'''Unreleased~~ structure~~'''~~	+	{{STRUCTURE_4nt4\| PDB=4nt4 \| SCENE= }}
		+	===Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster===

-	~~The entry~~ 4nt4 is ~~ON HOLD until Paper Publication~~	+	==About this Structure==
-		+	[[4nt4]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4NT4 OCA].
-	~~Authors~~: Chen, C.C., Shi, Z.B., Zhou, Z.C.	+	[[Category: Chen, C C.]]
-		+	[[Category: Shi, Z B.]]
-	~~Description~~: ~~Crystal structure of the~~ kinase ~~domain of Gilgamesh isoform I from Drosophila melanogaster~~	+	[[Category: Zhou, Z C.]]
		+	[[Category: Serine/threonine protein kinase]]
		+	[[Category: Transferase]]
		+	[[Category: Wnt signaling pathway]]

OCA: Protected "4nt4" [edit=sysop:move=sysop]

2013-12-11T13:07:19Z

Protected "4nt4" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:07, 11 December 2013

OCA: New page: '''Unreleased structure''' The entry 4nt4 is ON HOLD until Paper Publication Authors: Chen, C.C., Shi, Z.B., Zhou, Z.C. Description: Crystal structure of the kinase domain of Gilgamesh...

2013-12-11T13:07:19Z

New page: '''Unreleased structure''' The entry 4nt4 is ON HOLD until Paper Publication Authors: Chen, C.C., Shi, Z.B., Zhou, Z.C. Description: Crystal structure of the kinase domain of Gilgamesh...

New page

'''Unreleased structure'''

The entry 4nt4 is ON HOLD until Paper Publication

Authors: Chen, C.C., Shi, Z.B., Zhou, Z.C.

Description: Crystal structure of the kinase domain of Gilgamesh isoform I from Drosophila melanogaster