4oft - Revision history

OCA at 17:12, 20 September 2023

2023-09-20T17:12:34Z

←Older revision		Revision as of 17:12, 20 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Necator_americanus Necator americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OFT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Necator_americanus Necator americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OFT FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [https://pdbe.org/4oft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [https://www.ebi.ac.uk/pdbsum/4oft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [https://pdbe.org/4oft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [https://www.ebi.ac.uk/pdbsum/4oft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:22, 25 January 2023

2023-01-25T07:22:40Z

←Older revision		Revision as of 07:22, 25 January 2023
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	==C- Orthorombic NaGST1==		==C- Orthorombic NaGST1==
-	<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='4oft' size='340' side='right'caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human_hookworm Human hookworm~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4OFT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Necator_americanus Necator americanus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4OFT FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [https://pdbe.org/4oft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [https://www.ebi.ac.uk/pdbsum/4oft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gst-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=51031 Human hookworm])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [~~http~~://pdbe.org/4oft PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4oft PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D3U1A5_NECAM D3U1A5_NECAM]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 4oft" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4oft" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutathione S-transferase 3D structures\|Glutathione S-transferase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human hookworm~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Asojo, O A~~]]	+	[[Category: Necator americanus]]
-	[[Category: ~~Gst]]~~	+	[[Category: Asojo OA]]
-	~~[[Category: Transferase~~]]	+

OCA at 08:25, 22 November 2017

2017-11-22T08:25:18Z

←Older revision		Revision as of 08:25, 22 November 2017
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	<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human_hookworm Human hookworm]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">gst-1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=51031 Human hookworm])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [http://pdbe.org/4oft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [http://www.ebi.ac.uk/pdbsum/4oft PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [http://pdbe.org/4oft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [http://www.ebi.ac.uk/pdbsum/4oft PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 4oft" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4oft" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Glutathione S-transferase\|Glutathione S-transferase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human hookworm]]
	[[Category: Asojo, O A]]		[[Category: Asojo, O A]]
	[[Category: Gst]]		[[Category: Gst]]
	[[Category: Transferase]]		[[Category: Transferase]]

OCA at 17:00, 2 January 2017

2017-01-02T17:00:03Z

←Older revision		Revision as of 17:00, 2 January 2017
Line 1:		Line 1:
		+
	==C- Orthorombic NaGST1==		==C- Orthorombic NaGST1==
	<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFT FirstGlance]. <br>		<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFT FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [http://www.ebi.ac.uk/pdbsum/4oft PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [http://pdbe.org/4oft PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [http://www.ebi.ac.uk/pdbsum/4oft PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4oft ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4oft" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Glutathione S-transferase\|Glutathione S-transferase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:20, 3 December 2014

2014-12-03T09:20:30Z

←Older revision		Revision as of 09:20, 3 December 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==C- Orthorombic NaGST1==
		+	<StructureSection load='4oft' size='340' side='right' caption='[[4oft]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4oft]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4OFT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4OFT FirstGlance]. <br>
		+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2on7\|2on7]], [[4ofn\|4ofn]], [[4ofm\|4ofm]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4oft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4oft OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4oft RCSB], [http://www.ebi.ac.uk/pdbsum/4oft PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glutathione S-transferase 1 from Necator americanus (Na-GST-1) is a vaccine candidate for hookworm infection that has a high affinity for heme and metal porphyrins. As part of attempts to clarify the mechanism of heme detoxification by hookworm GSTs, co-crystallization and soaking studies of Na-GST-1 with the heme-like molecules protoporphyrin IX disodium salt, hematin and zinc protoporphyrin were undertaken. While these studies did not yield the structure of the complex of Na-GST-1 with any of these molecules, co-crystallization experiments resulted in the first structures of the complex of Na-GST-1 with the substrate glutathione. The structures of the complex of Na-GST-1 with glutathione were solved from pathological crystalline aggregates comprising more than one crystal form. These first structures of the complex of Na-GST-1 with the substrate glutathione were solved by molecular replacement from data collected with a sealed-tube home source using the previously reported apo structure as the search model.

-	~~The entry 4oft is ON HOLD until Paper Publication~~	+	Structure of glutathione S-transferase 1 from the major human hookworm parasite Necator americanus (Na-GST-1) in complex with glutathione.,Asojo OA, Ceccarelli C Acta Crystallogr F Struct Biol Commun. 2014 Sep;70(Pt 9):1162-6. doi:, 10.1107/S2053230X1401646X. Epub 2014 Aug 29. PMID:25195885<ref>PMID:25195885</ref>

-	~~Authors~~: Asojo, O.A.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~C-Orthorombic NaGST1~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Asojo, O A]]
		+	[[Category: Gst]]
		+	[[Category: Transferase]]

OCA at 12:14, 12 March 2014

2014-03-12T12:14:56Z

←Older revision		Revision as of 12:14, 12 March 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4oft is ON HOLD	+	The entry 4oft is ON HOLD until Paper Publication

	Authors: Asojo, O.A.		Authors: Asojo, O.A.

	Description: C-Orthorombic NaGST1		Description: C-Orthorombic NaGST1

OCA at 10:28, 5 February 2014

2014-02-05T10:28:19Z

←Older revision		Revision as of 10:28, 5 February 2014
Line 3:		Line 3:
	The entry 4oft is ON HOLD		The entry 4oft is ON HOLD

-	Authors: Asojo, O. A.	+	Authors: Asojo, O.A.

	Description: C-Orthorombic NaGST1		Description: C-Orthorombic NaGST1

OCA: Protected "4oft" [edit=sysop:move=sysop]

2014-01-22T06:48:38Z

Protected "4oft" [edit=sysop:move=sysop]

←Older revision

Revision as of 06:48, 22 January 2014

OCA: New page: '''Unreleased structure''' The entry 4oft is ON HOLD Authors: Asojo, O. A. Description: C-Orthorombic NaGST1

2014-01-22T06:48:37Z

New page: '''Unreleased structure''' The entry 4oft is ON HOLD Authors: Asojo, O. A. Description: C-Orthorombic NaGST1

New page

'''Unreleased structure'''

The entry 4oft is ON HOLD

Authors: Asojo, O. A.

Description: C-Orthorombic NaGST1