4qh3 - Revision history

OCA at 11:29, 15 February 2023

2023-02-15T11:29:44Z

←Older revision		Revision as of 11:29, 15 February 2023
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	<StructureSection load='4qh3' size='340' side='right'caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4qh3' size='340' side='right'caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I83:BIS(CHLORANYL)-(DIMETHYLAMINO)-(METHYLAMINO)PLATINUM'>I83</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I83:BIS(CHLORANYL)-(DIMETHYLAMINO)-(METHYLAMINO)PLATINUM'>I83</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [https://pdbe.org/4qh3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [https://www.ebi.ac.uk/pdbsum/4qh3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4qh3 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [~~http~~://pdbe.org/4qh3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4qh3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4qh3 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>	+	[https://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	==See Also==		==See Also==
-	*[[Ribonuclease\|Ribonuclease]]	+	*[[Ribonuclease 3D structures\|Ribonuclease 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 29:		Line 27:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pancreatic ribonuclease~~]]	+	[[Category: Merlino A]]
-	[[Category: Krauss, I ~~Russo]]~~	+	[[Category: Russo Krauss I]]
-	~~[[Category: Merlino, A]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Rna binding~~]]	+

OCA at 09:45, 24 April 2019

2019-04-24T09:45:19Z

←Older revision		Revision as of 09:45, 24 April 2019
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	==X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)==		==X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)==
-	<StructureSection load='4qh3' size='340' side='right' caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4qh3' size='340' side='right'caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Pancreatic ribonuclease]]		[[Category: Pancreatic ribonuclease]]
	[[Category: Krauss, I Russo]]		[[Category: Krauss, I Russo]]

OCA at 13:16, 4 August 2016

2016-08-04T13:16:55Z

←Older revision		Revision as of 13:16, 4 August 2016
Line 1:		Line 1:
		+
	==X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)==		==X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)==
	<StructureSection load='4qh3' size='340' side='right' caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4qh3' size='340' side='right' caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [http://pdbe.org/4qh3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4qh3 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4qh3" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribonuclease\|Ribonuclease]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:39, 25 December 2014

2014-12-25T09:39:01Z

←Older revision		Revision as of 09:39, 25 December 2014
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I83:BIS(CHLORANYL)-(DIMETHYLAMINO)-(METHYLAMINO)PLATINUM'>I83</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I83:BIS(CHLORANYL)-(DIMETHYLAMINO)-(METHYLAMINO)PLATINUM'>I83</scene></td></tr>
-	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>
-	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh3 PDBsum]</span></td></tr>
-	<table>	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RNAS1_BOVIN RNAS1_BOVIN]] Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA.<ref>PMID:7479688</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Pancreatic ribonuclease]]		[[Category: Pancreatic ribonuclease]]
-	[[Category: Krauss, I Russo.]]	+	[[Category: Krauss, I Russo]]
-	[[Category: Merlino, A.]]	+	[[Category: Merlino, A]]
	[[Category: Hydrolase]]		[[Category: Hydrolase]]
	[[Category: Rna binding]]		[[Category: Rna binding]]

OCA at 07:43, 30 July 2014

2014-07-30T07:43:16Z

←Older revision		Revision as of 07:43, 30 July 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)==
		+	<StructureSection load='4qh3' size='340' side='right' caption='[[4qh3]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4qh3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4QH3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4QH3 FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=I83:BIS(CHLORANYL)-(DIMETHYLAMINO)-(METHYLAMINO)PLATINUM'>I83</scene><br>
		+	<tr><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4qgz\|4qgz]]</td></tr>
		+	<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_ribonuclease Pancreatic ribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.27.5 3.1.27.5] </span></td></tr>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4qh3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4qh3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4qh3 RCSB], [http://www.ebi.ac.uk/pdbsum/4qh3 PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The adducts formed between trans-(dimethylamino)(methylamino)dichloridoplatinum(II), [t-PtCl2(dma)(ma)], and two model proteins, i.e., hen egg white lysozyme and bovine pancreatic ribonuclease, were independently characterized by X-ray crystallography and electrospray ionization mass spectrometry. In these adducts, the PtII center, upon chloride release, coordinates either to histidine or aspartic acid residues while both alkylamino ligands remain bound to the metal. Comparison with the cisplatin derivatives of the same proteins highlights for [t-PtCl2(dma)(ma)] a kind of biomolecular metalation remarkably different from that of cisplatin.

-	~~The entry 4qh3 is ON HOLD until Paper Publication~~	+	Interactions between Anticancer trans-Platinum Compounds and Proteins: Crystal Structures and ESI-MS Spectra of Two Protein Adducts of trans-(Dimethylamino)(methylamino)dichloridoplatinum(II).,Messori L, Marzo T, Michelucci E, Russo Krauss I, Navarro-Ranninger C, Quiroga AG, Merlino A Inorg Chem. 2014 Jul 15. PMID:25025479<ref>PMID:25025479</ref>

-	~~Authors~~: ~~Russo~~ Krauss, I., Merlino, A.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bos taurus]]
		+	[[Category: Pancreatic ribonuclease]]
		+	[[Category: Krauss, I Russo.]]
		+	[[Category: Merlino, A.]]
		+	[[Category: Hydrolase]]
		+	[[Category: Rna binding]]

OCA at 05:54, 25 June 2014

2014-06-25T05:54:07Z

←Older revision		Revision as of 05:54, 25 June 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4qh3 is ON HOLD	+	The entry 4qh3 is ON HOLD until Paper Publication

	Authors: Russo Krauss, I., Merlino, A.		Authors: Russo Krauss, I., Merlino, A.

	Description: X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)		Description: X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)

OCA: Protected "4qh3" [edit=sysop:move=sysop]

2014-06-04T04:58:45Z

Protected "4qh3" [edit=sysop:move=sysop]

←Older revision

Revision as of 04:58, 4 June 2014

OCA: New page: '''Unreleased structure''' The entry 4qh3 is ON HOLD Authors: Russo Krauss, I., Merlino, A. Description: X-ray structure of the adduct formed between bovine pancreatic ribonuclease and...

2014-06-04T04:58:44Z

New page: '''Unreleased structure''' The entry 4qh3 is ON HOLD Authors: Russo Krauss, I., Merlino, A. Description: X-ray structure of the adduct formed between bovine pancreatic ribonuclease and...

New page

'''Unreleased structure'''

The entry 4qh3 is ON HOLD

Authors: Russo Krauss, I., Merlino, A.

Description: X-ray structure of the adduct formed between bovine pancreatic ribonuclease and trans-dimethylamine methylamine dichlorido platinum(II)