4r8v - Revision history

OCA at 15:13, 8 November 2023

2023-11-08T15:13:05Z

←Older revision		Revision as of 15:13, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R8V FirstGlance]. <br>		<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R8V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.197Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [https://pdbe.org/4r8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [https://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [https://pdbe.org/4r8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [https://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:45, 2 March 2023

2023-03-02T06:45:18Z

←Older revision		Revision as of 06:45, 2 March 2023
Line 3:		Line 3:
	<StructureSection load='4r8v' size='340' side='right'caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4r8v' size='340' side='right'caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Brachidanio_rerio Brachidanio~~ rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4R8V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Danio_rerio Danio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4R8V FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [https://pdbe.org/4r8v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [https://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aldh1l1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [~~http~~://pdbe.org/4r8v PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/E3NZ06_DANRE E3NZ06_DANRE]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Brachidanio~~ rerio]]	+	[[Category: Danio rerio]]
-	~~[[Category: Formyltetrahydrofolate dehydrogenase~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Chang~~, W N~~]]	+	[[Category: Chang WN]]
-	[[Category: Chen~~, C J~~]]	+	[[Category: Chen CJ]]
-	[[Category: Chuankhayan, P]]	+	[[Category: Chuankhayan P]]
-	[[Category: Fu~~, T F~~]]	+	[[Category: Fu TF]]
-	[[Category: Kao~~, T T~~]]	+	[[Category: Kao TT]]
-	[[Category: Lin~~, C C]]~~	+	[[Category: Lin CC]]
-	~~[[Category: 10-formyltetrahydrofolate dehydrogenase]]~~	+
-	~~[[Category: Catalysis]]~~	+
-	~~[[Category: Hydrolase domain]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 08:23, 18 December 2019

2019-12-18T08:23:33Z

←Older revision		Revision as of 08:23, 18 December 2019
Line 10:		Line 10:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://pdbe.org/4r8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://pdbe.org/4r8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	10-Formyltetrahydrofolate dehydrogenase (FDH), which is composed of a small N-terminal domain (Nt-FDH) and a large C-terminal domain, is an abundant folate enzyme in the liver and converts 10-formyltetrahydrofolate (10-FTHF) to tetrahydrofolate (THF) and CO2. Nt-FDH alone possesses a hydrolase activity, which converts 10-FTHF to THF and formate in the presence of beta-mercaptoethanol. To elucidate the catalytic mechanism of Nt-FDH, crystal structures of apo-form zNt-FDH from zebrafish and its complexes with the substrate analogue 10-formyl-5,8-dideazafolate (10-FDDF) and with the products THF and formate have been determined. The structures reveal that the conformations of three loops (residues 86-90, 135-143 and 200-203) are altered upon ligand (10-FDDF or THF) binding in the active site. The orientations and geometries of key residues, including Phe89, His106, Arg114, Asp142 and Tyr200, are adjusted for substrate binding and product release during catalysis. Among them, Tyr200 is especially crucial for product release. An additional potential THF binding site is identified in the cavity between two zNt-FDH molecules, which might contribute to the properties of product inhibition and THF storage reported for FDH. Together with mutagenesis studies and activity assays, the structures of zNt-FDH and its complexes provide a coherent picture of the active site and a potential THF binding site of zNt-FDH along with the substrate and product specificity, lending new insights into the molecular mechanism underlying the enzymatic properties of Nt-FDH.
		+
		+	Structures of the hydrolase domain of zebrafish 10-formyltetrahydrofolate dehydrogenase and its complexes reveal a complete set of key residues for hydrolysis and product inhibition.,Lin CC, Chuankhayan P, Chang WN, Kao TT, Guan HH, Fun HK, Nakagawa A, Fu TF, Chen CJ Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):1006-21. doi:, 10.1107/S1399004715002928. Epub 2015 Mar 27. PMID:25849409<ref>PMID:25849409</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 4r8v" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:39, 1 May 2019

2019-05-01T09:39:15Z

←Older revision		Revision as of 09:39, 1 May 2019
Line 1:		Line 1:

	==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate==		==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate==
-	<StructureSection load='4r8v' size='340' side='right' caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>	+	<StructureSection load='4r8v' size='340' side='right'caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R8V FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Brachidanio_rerio Brachidanio rerio]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R8V FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">aldh1l1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7955 Brachidanio rerio])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://pdbe.org/4r8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://pdbe.org/4r8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>
Line 11:		Line 12:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Brachidanio rerio]]
	[[Category: Formyltetrahydrofolate dehydrogenase]]		[[Category: Formyltetrahydrofolate dehydrogenase]]
		+	[[Category: Large Structures]]
	[[Category: Chang, W N]]		[[Category: Chang, W N]]
	[[Category: Chen, C J]]		[[Category: Chen, C J]]

OCA at 17:19, 18 January 2017

2017-01-18T17:19:04Z

←Older revision		Revision as of 17:19, 18 January 2017
Line 1:		Line 1:
		+
	==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate==		==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate==
	<StructureSection load='4r8v' size='340' side='right' caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>		<StructureSection load='4r8v' size='340' side='right' caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://pdbe.org/4r8v PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4r8v ProSAT]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 12:59, 15 April 2015

2015-04-15T12:59:49Z

←Older revision		Revision as of 12:59, 15 April 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate==
-		+	<StructureSection load='4r8v' size='340' side='right' caption='[[4r8v]], [[Resolution\|resolution]] 2.20Å' scene=''>
-	~~The entry~~ 4r8v is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4r8v]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4R8V OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4R8V FirstGlance]. <br>
-	~~Authors~~: ~~Lin, C~~.C.~~, Chen, C~~.J.~~, Fu, T~~.F.~~, Chuankhayan, P~~.~~, Kao, T~~.~~T., Chang, W.N~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BTB:2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>BTB</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ts4\|4ts4]], [[4tt8\|4tt8]], [[4qpd\|4qpd]], [[4qpc\|4qpc]], [[4tts\|4tts]]</td></tr>
-	~~Description~~: ~~Crystal structure of the hydrolase domain of 10~~-~~formyltetrahydrofolate dehydrogenase~~ (~~wild~~-~~type~~) ~~complex with formate~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Formyltetrahydrofolate_dehydrogenase Formyltetrahydrofolate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.5.1.6 1.5.1.6] </span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4r8v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4r8v OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4r8v RCSB], [http://www.ebi.ac.uk/pdbsum/4r8v PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Chang~~, W.N]]	+	</table>
-	[[~~Category~~: Fu, T.F]]	+	__TOC__
-	[[Category: ~~Lin, C.C~~]]	+	</StructureSection>
-	[[Category: ~~Kao~~, ~~T.T~~]]	+	[[Category: Formyltetrahydrofolate dehydrogenase]]
-	[[Category: Chen, C.J]]	+	[[Category: Chang, W N]]
		+	[[Category: Chen, C J]]
	[[Category: Chuankhayan, P]]		[[Category: Chuankhayan, P]]
		+	[[Category: Fu, T F]]
		+	[[Category: Kao, T T]]
		+	[[Category: Lin, C C]]
		+	[[Category: 10-formyltetrahydrofolate dehydrogenase]]
		+	[[Category: Catalysis]]
		+	[[Category: Hydrolase domain]]
		+	[[Category: Oxidoreductase]]

OCA at 16:37, 24 December 2014

2014-12-24T16:37:56Z

←Older revision		Revision as of 16:37, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate		Description: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate
		+	[[Category: Unreleased Structures]]
		+	[[Category: Chang, W.N]]
		+	[[Category: Fu, T.F]]
		+	[[Category: Lin, C.C]]
		+	[[Category: Kao, T.T]]
		+	[[Category: Chen, C.J]]
		+	[[Category: Chuankhayan, P]]

OCA at 08:25, 24 September 2014

2014-09-24T08:25:56Z

←Older revision		Revision as of 08:25, 24 September 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4r8v is ON HOLD	+	The entry 4r8v is ON HOLD until Paper Publication

	Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N.		Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N.

	Description: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate		Description: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate

OCA: Protected "4r8v" [edit=sysop:move=sysop]

2014-09-10T08:26:47Z

Protected "4r8v" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:26, 10 September 2014

OCA: New page: '''Unreleased structure''' The entry 4r8v is ON HOLD Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N. Description: Crystal structure of the hydrolase d...

2014-09-10T08:26:45Z

New page: '''Unreleased structure''' The entry 4r8v is ON HOLD Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N. Description: Crystal structure of the hydrolase d...

New page

'''Unreleased structure'''

The entry 4r8v is ON HOLD

Authors: Lin, C.C., Chen, C.J., Fu, T.F., Chuankhayan, P., Kao, T.T., Chang, W.N.

Description: Crystal structure of the hydrolase domain of 10-formyltetrahydrofolate dehydrogenase (wild-type) complex with formate