4rvr - Revision history

OCA at 17:57, 20 September 2023

2023-09-20T17:57:06Z

←Older revision		Revision as of 17:57, 20 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVR FirstGlance]. <br>		<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.98Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [https://pdbe.org/4rvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [https://www.ebi.ac.uk/pdbsum/4rvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvr ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [https://pdbe.org/4rvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [https://www.ebi.ac.uk/pdbsum/4rvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvr ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:30, 8 March 2023

2023-03-08T08:30:20Z

←Older revision		Revision as of 08:30, 8 March 2023
Line 3:		Line 3:
	<StructureSection load='4rvr' size='340' side='right'caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4rvr' size='340' side='right'caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4RVR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4RVR FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ir3\|4ir3]], [[4ir4\|4ir4]], [[4ir5\|4ir5]], [[4ir6\|4ir6]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [https://pdbe.org/4rvr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [https://www.ebi.ac.uk/pdbsum/4rvr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvr ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [~~http~~://pdbe.org/4rvr PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4rvr PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvr ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.	+	[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arrowsmith~~, C H~~]]	+	[[Category: Arrowsmith CH]]
-	[[Category: Bountra, C]]	+	[[Category: Bountra C]]
-	[[Category: Chaikuad, A]]	+	[[Category: Chaikuad A]]
-	[[Category: Chen, P]]	+	[[Category: Chen P]]
-	[[Category: Chung~~, C W]]~~	+	[[Category: Chung CW]]
-	~~[[Category: Delft, F von~~]]	+	[[Category: Drewry D]]
-	[[Category: Drewry, D]]	+	[[Category: Edwards AM]]
-	[[Category: Edwards~~, A M~~]]	+	[[Category: Fedorov O]]
-	[[Category: Fedorov, O]]	+	[[Category: Felletar I]]
-	[[Category: Felletar, I]]	+	[[Category: Filippakopoulos P]]
-	[[Category: Filippakopoulos, P]]	+	[[Category: Knapp S]]
-	[[Category: Knapp, S]]	+	[[Category: Von Delft F]]
-	[[Category: ~~Structural genomic]]~~	+
-	~~[[Category: Acetylated lysine binding protein]]~~	+
-	~~[[Category: Chemical probe]]~~	+
-	~~[[Category: Kiaa1476]]~~	+
-	~~[[Category: Sgc]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Walp4~~]]	+

OCA at 10:36, 1 May 2019

2019-05-01T10:36:22Z

←Older revision		Revision as of 10:36, 1 May 2019
Line 1:		Line 1:

	==Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801==		==Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801==
-	<StructureSection load='4rvr' size='340' side='right' caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>	+	<StructureSection load='4rvr' size='340' side='right'caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVR FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVR FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ir3\|4ir3]], [[4ir4\|4ir4]], [[4ir5\|4ir5]], [[4ir6\|4ir6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ir3\|4ir3]], [[4ir4\|4ir4]], [[4ir5\|4ir5]], [[4ir6\|4ir6]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://pdbe.org/4rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BAZ2B, KIAA1476 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://pdbe.org/4rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4rvr ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 4rvr" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4rvr" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Bromodomain adjacent to zinc finger 3D structures\|Bromodomain adjacent to zinc finger 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Arrowsmith, C H]]		[[Category: Arrowsmith, C H]]
	[[Category: Bountra, C]]		[[Category: Bountra, C]]

OCA at 17:30, 10 May 2016

2016-05-10T17:30:53Z

←Older revision		Revision as of 17:30, 10 May 2016
Line 1:		Line 1:
		+
	==Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801==		==Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801==
	<StructureSection load='4rvr' size='340' side='right' caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>		<StructureSection load='4rvr' size='340' side='right' caption='[[4rvr]], [[Resolution\|resolution]] 1.98Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ir3\|4ir3]], [[4ir4\|4ir4]], [[4ir5\|4ir5]], [[4ir6\|4ir6]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ir3\|4ir3]], [[4ir4\|4ir4]], [[4ir5\|4ir5]], [[4ir6\|4ir6]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://pdbe.org/4rvr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4rvr" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 07:02, 15 April 2015

2015-04-15T07:02:24Z

←Older revision		Revision as of 07:02, 15 April 2015
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.		[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Bromodomains are acetyl-lysine specific protein interaction domains that have recently emerged as a new target class for the development of inhibitors that modulate gene transcription. The two closely related bromodomain containing proteins BAZ2A and BAZ2B constitute the central scaffolding protein of the nucleolar remodeling complex (NoRC) that regulates the expression of noncoding RNAs. However, BAZ2 bromodomains have low predicted druggability and so far no selective inhibitors have been published. Here we report the development of GSK2801, a potent, selective and cell active acetyl-lysine competitive inhibitor of BAZ2A and BAZ2B bromodomains as well as the inactive control compound GSK8573. GSK2801 binds to BAZ2 bromodomains with dissociation constants (KD) of 136 and 257 nM for BAZ2B and BAZ2A, respectively. Crystal structures demonstrated a canonical acetyl-lysine competitive binding mode. Cellular activity was demonstrated using fluorescent recovery after photobleaching (FRAP) monitoring displacement of GFP-BAZ2A from acetylated chromatin. A pharmacokinetic study in mice showed that GSK2801 had reasonable in vivo exposure after oral dosing, with modest clearance and reasonable plasma stability. Thus, GSK2801 represents a versatile tool compound for cellular and in vivo studies to understand the role of BAZ2 bromodomains in chromatin biology.
		+
		+	Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B.,Chen P, Chaikuad A, Bamborough P, Bantscheff M, Bountra C, Chung CW, Fedorov O, Grandi P, Jung D, Lesniak R, Lindon M, Muller S, Philpott M, Prinjha R, Rogers C, Selenski C, Tallant C, Werner T, Willson TM, Knapp S, Drewry DH J Med Chem. 2015 Apr 6. PMID:25799074<ref>PMID:25799074</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 21:18, 25 December 2014

2014-12-25T21:18:09Z

←Older revision		Revision as of 21:18, 25 December 2014
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA: Protected "4rvr" [edit=sysop:move=sysop]

2014-12-10T16:27:24Z

Protected "4rvr" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:27, 10 December 2014

OCA: New page: ==Crystal Structure of the bromodomain of human BAZ2B in complex WITH GSK2801== == Structural highlights ==
<table><tr><td colspan='2'>[[4rvr]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4RVR OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4RVR FirstGlance]. 
</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=3WQ:1-{1-[2-(METHYLSULFONYL)PHENYL]-7-PROPOXYINDOLIZIN-3-YL}ETHANONE'>3WQ</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
<tr id='related'><td class="sblockLbl">[[Related_structure|Related:]]</td><td class="sblockDat">[[4ir3|4ir3]], [[4ir4|4ir4]], [[4ir5|4ir5]], [[4ir6|4ir6]]</td></tr>
<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4rvr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4rvr OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4rvr RCSB], [http://www.ebi.ac.uk/pdbsum/4rvr PDBsum]</td></tr>
</table>
TOC
</StructureSection>
[[Category: Arrowsmith, C H]]
[[Category: Bountra, C]]
[[Category: Chaikuad, A]]
[[Category: Chen, P]]
[[Category: Chung, C W]]
[[Category: Delft, F von]]
[[Category: Drewry, D]]
[[Category: Edwards, A M]]
[[Category: Fedorov, O]]
[[Category: Felletar, I]]
[[Category: Filippakopoulos, P]]
[[Category: Knapp, S]]
[[Category: Structural genomic]]
[[Category: Acetylated lysine binding protein]]
[[Category: Chemical probe]]
[[Category: Kiaa1476]]
[[Category: Sgc]]
[[Category: Transcription]]
[[Category: Walp4]]