4tzo - Revision history

OCA at 07:24, 27 September 2023

2023-09-27T07:24:31Z

←Older revision		Revision as of 07:24, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TZO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [https://pdbe.org/4tzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [https://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [https://pdbe.org/4tzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [https://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 07:53, 22 March 2023

2023-03-22T07:53:25Z

←Older revision		Revision as of 07:53, 22 March 2023
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	<StructureSection load='4tzo' size='340' side='right'caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4tzo' size='340' side='right'caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Caeel Caeel~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4TZO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
-	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [https://pdbe.org/4tzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [https://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">htp-1, CELE_F41H10.10, F41H10.10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL]), him-3, CELE_ZK381.1, ZK381.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [~~http~~://pdbe.org/4tzo PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q20305_CAEEL Q20305_CAEEL]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Caeel~~]]	+	[[Category: Caenorhabditis elegans]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Corbett~~, K D~~]]	+	[[Category: Corbett KD]]
-	[[Category: Rosenberg~~, S C]]~~	+	[[Category: Rosenberg SC]]
-	~~[[Category: Chromosome axis]]~~	+
-	~~[[Category: Horma domain]]~~	+
-	~~[[Category: Meiosis]]~~	+
-	~~[[Category: Peptide binding protein~~]]	+

OCA at 10:21, 25 December 2019

2019-12-25T10:21:42Z

←Older revision		Revision as of 10:21, 25 December 2019
Line 1:		Line 1:

	==Structure of C. elegans HTP-1 bound to HIM-3 closure motif==		==Structure of C. elegans HTP-1 bound to HIM-3 closure motif==
-	<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='4tzo' size='340' side='right'caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
Line 22:		Line 22:
	</StructureSection>		</StructureSection>
	[[Category: Caeel]]		[[Category: Caeel]]
		+	[[Category: Large Structures]]
	[[Category: Corbett, K D]]		[[Category: Corbett, K D]]
	[[Category: Rosenberg, S C]]		[[Category: Rosenberg, S C]]

OCA at 15:02, 15 November 2017

2017-11-15T15:02:57Z

←Older revision		Revision as of 15:02, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Caeel Caeel]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">htp-1, CELE_F41H10.10, F41H10.10 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL]), him-3, CELE_ZK381.1, ZK381.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 CAEEL])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://pdbe.org/4tzo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://pdbe.org/4tzo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Caeel]]
	[[Category: Corbett, K D]]		[[Category: Corbett, K D]]
	[[Category: Rosenberg, S C]]		[[Category: Rosenberg, S C]]

OCA at 13:17, 5 August 2016

2016-08-05T13:17:27Z

←Older revision		Revision as of 13:17, 5 August 2016
Line 1:		Line 1:
		+
	==Structure of C. elegans HTP-1 bound to HIM-3 closure motif==		==Structure of C. elegans HTP-1 bound to HIM-3 closure motif==
	<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>		<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://pdbe.org/4tzo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4tzo ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4tzo" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:37, 17 December 2014

2014-12-17T09:37:04Z

←Older revision		Revision as of 09:37, 17 December 2014
Line 6:		Line 6:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Proteins of the HORMA domain family play central, but poorly understood, roles in chromosome organization and dynamics during meiosis. In Caenorhabditis elegans, four such proteins (HIM-3, HTP-1, HTP-2, and HTP-3) have distinct but overlapping functions. Through combined biochemical, structural, and in vivo analysis, we find that these proteins form hierarchical complexes through binding of their HORMA domains to cognate peptides within their partners' C-terminal tails, analogous to the "safety belt" binding mechanism of Mad2. These interactions are critical for recruitment of HIM-3, HTP-1, and HTP-2 to chromosome axes. HTP-3, in addition to recruiting the other HORMA domain proteins to the axis, plays an independent role in sister chromatid cohesion and double-strand break formation. Finally, we find that mammalian HORMAD1 binds a motif found both at its own C terminus and at that of HORMAD2, indicating that this mode of intermolecular association is a conserved feature of meiotic chromosome structure in eukaryotes.
		+
		+	The Chromosome Axis Controls Meiotic Events through a Hierarchical Assembly of HORMA Domain Proteins.,Kim Y, Rosenberg SC, Kugel CL, Kostow N, Rog O, Davydov V, Su TY, Dernburg AF, Corbett KD Dev Cell. 2014 Nov 24;31(4):487-502. doi: 10.1016/j.devcel.2014.09.013. Epub 2014, Nov 6. PMID:25446517<ref>PMID:25446517</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 12:58, 19 November 2014

2014-11-19T12:58:34Z

←Older revision		Revision as of 12:58, 19 November 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Structure of C. elegans HTP-1 bound to HIM-3 closure motif==
-		+	<StructureSection load='4tzo' size='340' side='right' caption='[[4tzo]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~The entry~~ 4tzo is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4tzo]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4TZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4TZO FirstGlance]. <br>
-	~~Authors~~: ~~Rosenberg~~, S.C., ~~Corbett~~, K.D.	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4tzj\|4tzj]], [[4tzl\|4tzl]], [[4tzm\|4tzm]], [[4tzn\|4tzn]], [[4tzq\|4tzq]], [[4tzs\|4tzs]], [[4trk\|4trk]]</td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4tzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4tzo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4tzo RCSB], [http://www.ebi.ac.uk/pdbsum/4tzo PDBsum]</span></td></tr>
-	~~Description~~: ~~Structure of~~ C~~. elegans HTP-1 bound to HIM-3 closure motif~~	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Corbett, K D]]
		+	[[Category: Rosenberg, S C]]
		+	[[Category: Chromosome axis]]
		+	[[Category: Horma domain]]
		+	[[Category: Meiosis]]
		+	[[Category: Peptide binding protein]]

OCA at 07:12, 30 July 2014

2014-07-30T07:12:44Z

←Older revision		Revision as of 07:12, 30 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4tzo is ON HOLD	+	The entry 4tzo is ON HOLD until Paper Publication

	Authors: Rosenberg, S.C., Corbett, K.D.		Authors: Rosenberg, S.C., Corbett, K.D.

	Description: Structure of C. elegans HTP-1 bound to HIM-3 closure motif		Description: Structure of C. elegans HTP-1 bound to HIM-3 closure motif

OCA: Protected "4tzo" [edit=sysop:move=sysop]

2014-07-16T09:58:40Z

Protected "4tzo" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:58, 16 July 2014

OCA: New page: '''Unreleased structure''' The entry 4tzo is ON HOLD Authors: Rosenberg, S.C., Corbett, K.D. Description: Structure of C. elegans HTP-1 bound to HIM-3 closure motif

2014-07-16T09:58:39Z

New page: '''Unreleased structure''' The entry 4tzo is ON HOLD Authors: Rosenberg, S.C., Corbett, K.D. Description: Structure of C. elegans HTP-1 bound to HIM-3 closure motif

New page

'''Unreleased structure'''

The entry 4tzo is ON HOLD

Authors: Rosenberg, S.C., Corbett, K.D.

Description: Structure of C. elegans HTP-1 bound to HIM-3 closure motif