4uez - Revision history

OCA at 12:29, 20 December 2023

2023-12-20T12:29:23Z

←Older revision		Revision as of 12:29, 20 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.29Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [https://pdbe.org/4uez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [https://www.ebi.ac.uk/pdbsum/4uez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uez ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [https://pdbe.org/4uez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [https://www.ebi.ac.uk/pdbsum/4uez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uez ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:21, 22 March 2023

2023-03-22T08:21:06Z

←Older revision		Revision as of 08:21, 22 March 2023
Line 3:		Line 3:
	<StructureSection load='4uez' size='340' side='right'caption='[[4uez]], [[Resolution\|resolution]] 2.29Å' scene=''>		<StructureSection load='4uez' size='340' side='right'caption='[[4uez]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uee\|4uee]], [[4uef\|4uef]], [[4uf4\|4uf4]], [[5aek\|5aek]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [https://pdbe.org/4uez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [https://www.ebi.ac.uk/pdbsum/4uez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uez ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [~~http~~://pdbe.org/4uez PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4uez PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4uez ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>	+	[https://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>

	==See Also==		==See Also==
Line 18:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Carboxypeptidase A]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aviles~~, F X~~]]	+	[[Category: Aviles FX]]
-	[[Category: Costenaro, L]]	+	[[Category: Costenaro L]]
-	[[Category: Covaleda, G]]	+	[[Category: Covaleda G]]
-	[[Category: Devel, L]]	+	[[Category: Devel L]]
-	[[Category: Dive, V]]	+	[[Category: Dive V]]
-	[[Category: Gallego, P]]	+	[[Category: Gallego P]]
-	[[Category: Reverter, D]]	+	[[Category: Reverter D]]
-	~~[[Category: Carboxypeptidase]]~~	+
-	~~[[Category: Cpa1]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Phosphinic inhibitor~~]]	+

OCA at 09:04, 21 May 2019

2019-05-21T09:04:11Z

←Older revision		Revision as of 09:04, 21 May 2019
Line 1:		Line 1:
		+
	==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH==		==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH==
-	<StructureSection load='4uez' size='340' side='right' caption='[[4uez]], [[Resolution\|resolution]] 2.29Å' scene=''>	+	<StructureSection load='4uez' size='340' side='right'caption='[[4uez]], [[Resolution\|resolution]] 2.29Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uee\|4uee]], [[4uef\|4uef]], [[4uf4\|4uf4]], [[5aek\|5aek]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uee\|4uee]], [[4uef\|4uef]], [[4uf4\|4uf4]], [[5aek\|5aek]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [http://pdbe.org/4uez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [http://www.ebi.ac.uk/pdbsum/4uez PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [http://pdbe.org/4uez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [http://www.ebi.ac.uk/pdbsum/4uez PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uez ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>		[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
		+
		+	==See Also==
		+	*[[Carboxypeptidase 3D structures\|Carboxypeptidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 15:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Carboxypeptidase A]]		[[Category: Carboxypeptidase A]]
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Aviles, F X]]		[[Category: Aviles, F X]]
	[[Category: Costenaro, L]]		[[Category: Costenaro, L]]

OCA at 17:10, 20 January 2016

2016-01-20T17:10:42Z

←Older revision		Revision as of 17:10, 20 January 2016
Line 1:		Line 1:
-	~~'''Unreleased structure'''~~	+	==Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH==
-		+	<StructureSection load='4uez' size='340' side='right' caption='[[4uez]], [[Resolution\|resolution]] 2.29Å' scene=''>
-	~~The entry 4uez is ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4uez]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UEZ FirstGlance]. <br>
-	~~Authors: Gallego, P., Covaleda, G., Costenaro, L., Devel, L., Dive, V., Aviles, F.X., Reverter, D.~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=LFF:(2S)-3-[(R)-{(1R)-1-[(N-ACETYL-L-LEUCYL)AMINO]-2-PHENYLETHYL}(HYDROXY)PHOSPHORYL]-2-BENZYLPROPANOIC+ACID'>LFF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4uee\|4uee]], [[4uef\|4uef]], [[4uf4\|4uf4]], [[5aek\|5aek]]</td></tr>
-	~~Description:~~ Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Carboxypeptidase_A Carboxypeptidase A], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.17.1 3.4.17.1] </span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uez OCA], [http://pdbe.org/4uez PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uez RCSB], [http://www.ebi.ac.uk/pdbsum/4uez PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Dive~~, V]]	+	</table>
-	[[~~Category~~: ~~Gallego~~, P]]	+	== Function ==
-	[[~~Category~~: ~~Aviles~~, F.X]]	+	[[http://www.uniprot.org/uniprot/CBPA1_HUMAN CBPA1_HUMAN]] Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro.<ref>PMID:8806703</ref>
-	[[Category: ~~Reverter~~, D]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Carboxypeptidase A]]
		+	[[Category: Aviles, F X]]
	[[Category: Costenaro, L]]		[[Category: Costenaro, L]]
	[[Category: Covaleda, G]]		[[Category: Covaleda, G]]
	[[Category: Devel, L]]		[[Category: Devel, L]]
		+	[[Category: Dive, V]]
		+	[[Category: Gallego, P]]
		+	[[Category: Reverter, D]]
		+	[[Category: Carboxypeptidase]]
		+	[[Category: Cpa1]]
		+	[[Category: Hydrolase]]
		+	[[Category: Phosphinic inhibitor]]

OCA at 22:56, 30 November 2015

2015-11-30T22:56:47Z

←Older revision		Revision as of 22:56, 30 November 2015
Line 7:		Line 7:
	Description: Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH		Description: Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Gallego, P]]
-	[[Category: Reverter, D]]
	[[Category: Dive, V]]		[[Category: Dive, V]]
		+	[[Category: Gallego, P]]
	[[Category: Aviles, F.X]]		[[Category: Aviles, F.X]]
		+	[[Category: Reverter, D]]
	[[Category: Costenaro, L]]		[[Category: Costenaro, L]]
	[[Category: Covaleda, G]]		[[Category: Covaleda, G]]
	[[Category: Devel, L]]		[[Category: Devel, L]]

OCA: Protected "4uez" [edit=sysop:move=sysop]

2014-12-31T12:45:44Z

Protected "4uez" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:45, 31 December 2014

OCA: New page: '''Unreleased structure''' The entry 4uez is ON HOLD until Paper Publication Authors: Gallego, P., Covaleda, G., Costenaro, L., Devel, L., Dive, V., Aviles, F.X., Reverter, D. Descript...

2014-12-31T12:45:43Z

New page: '''Unreleased structure''' The entry 4uez is ON HOLD until Paper Publication Authors: Gallego, P., Covaleda, G., Costenaro, L., Devel, L., Dive, V., Aviles, F.X., Reverter, D. Descript...

New page

'''Unreleased structure'''

The entry 4uez is ON HOLD until Paper Publication

Authors: Gallego, P., Covaleda, G., Costenaro, L., Devel, L., Dive, V., Aviles, F.X., Reverter, D.

Description: Crystal structure of the human CARBOXYPEPTIDASE A1 in complex with the PHOSPHINIC INHIBITOR Acetyl-Leu-Phe-Y(PO2CH2)-Phe-OH
[[Category: Unreleased Structures]]
[[Category: Gallego, P]]
[[Category: Reverter, D]]
[[Category: Dive, V]]
[[Category: Aviles, F.X]]
[[Category: Costenaro, L]]
[[Category: Covaleda, G]]
[[Category: Devel, L]]