4um3 - Revision history

OCA at 10:30, 10 January 2024

2024-01-10T10:30:21Z

←Older revision		Revision as of 10:30, 10 January 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.703Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [https://pdbe.org/4um3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [https://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [https://pdbe.org/4um3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [https://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 08:28, 22 March 2023

2023-03-22T08:28:46Z

←Older revision		Revision as of 08:28, 22 March 2023
Line 3:		Line 3:
	<StructureSection load='4um3' size='340' side='right'caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='4um3' size='340' side='right'caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Great_pond_snail Great pond snail~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [https://en.wikipedia.org/wiki/Lymnaea_stagnalis Lymnaea stagnalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4um1\|4um1]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [https://pdbe.org/4um3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [https://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [~~http~~://pdbe.org/4um3 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.	+	[https://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST] Binds to acetylcholine. Modulates neuronal synaptic transmission.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Great pond snail]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Balle, T]]	+	[[Category: Lymnaea stagnalis]]
-	[[Category: Gajhede, M]]	+	[[Category: Balle T]]
-	[[Category: Kastrup~~, J S~~]]	+	[[Category: Gajhede M]]
-	[[Category: Shahsavar, A]]	+	[[Category: Kastrup JS]]
-	~~[[Category: Cys-loop receptor]]~~	+	[[Category: Shahsavar A]]
-	~~[[Category: Ion channel]]~~	+
-	~~[[Category: Nicotinic acetylcholine receptor]]~~	+
-	~~[[Category: Receptor stoichiometry]]~~	+
-	~~[[Category: Signaling protein~~]]	+

OCA at 10:59, 26 February 2020

2020-02-26T10:59:20Z

←Older revision		Revision as of 10:59, 26 February 2020
Line 1:		Line 1:
-	~~{{Large structure}}~~	+
	==Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920==		==Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920==
-	<StructureSection load='4um3' size='340' side='right' caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>	+	<StructureSection load='4um3' size='340' side='right'caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [http://en.wikipedia.org/wiki/Great_pond_snail Great pond snail]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [http://en.wikipedia.org/wiki/Great_pond_snail Great pond snail]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://pdbe.org/4um3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://pdbe.org/4um3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>
	</table>		</table>
-	{{Large structure}}
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.		[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.
Line 25:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Great pond snail]]		[[Category: Great pond snail]]
		+	[[Category: Large Structures]]
	[[Category: Balle, T]]		[[Category: Balle, T]]
	[[Category: Gajhede, M]]		[[Category: Gajhede, M]]

OCA at 10:07, 15 November 2017

2017-11-15T10:07:03Z

←Older revision		Revision as of 10:07, 15 November 2017
Line 1:		Line 1:
-	==Engineered Ls-AChBP with alpha4-alpha4 ~~interface~~ in complex with NS3920==	+	{{Large structure}}
		+	==Engineered Ls-AChBP with alpha4-alpha4 binding pocket in complex with NS3920==
	<StructureSection load='4um3' size='340' side='right' caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>		<StructureSection load='4um3' size='340' side='right' caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure with sequence from [http://en.wikipedia.org/wiki/Great_pond_snail Great pond snail]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4um1\|4um1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4um1\|4um1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://pdbe.org/4um3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4um3 ProSAT]</span></td></tr>
	</table>		</table>
	{{Large structure}}		{{Large structure}}
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4um3" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Great pond snail]]
	[[Category: Balle, T]]		[[Category: Balle, T]]
	[[Category: Gajhede, M]]		[[Category: Gajhede, M]]

OCA at 06:42, 2 September 2015

2015-09-02T06:42:10Z

←Older revision		Revision as of 06:42, 2 September 2015
Line 7:		Line 7:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum]</span></td></tr>
	</table>		</table>
		+	{{Large structure}}
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.		[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.

OCA at 08:37, 29 July 2015

2015-07-29T08:37:58Z

←Older revision		Revision as of 08:37, 29 July 2015
Line 9:		Line 9:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.		[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Neuronal alpha4beta2 nicotinic acetylcholine receptors are attractive drug targets for psychiatric and neurodegenerative disorders and smoking cessation aids. Recently, a third agonist binding site between two alpha4 subunits in the (alpha4)3(beta2)2 receptor sub-population was discovered. In particular, three residues, H142, Q150, and T152, were demonstrated to be involved in the distinct pharmacology of the alpha4-alpha4 vs. alpha4-beta2 binding sites. To obtain insight into the 3-dimensional structure of the alpha4-alpha4 binding site, a surrogate protein reproducing alpha4-alpha4 binding characteristics was constructed by introduction of three point mutations, R104H, L112Q, and M114T, into the binding pocket of Lymnaea stagnalis acetylcholine binding protein (Ls-AChBP). Co-crystallization with two agonists possessing distinct pharmacological profiles, NS3920 and NS3573, highlights the roles of the three residues in determining binding affinities and functional properties of ligands at the alpha4-alpha4 interface. Confirmed by mutational studies, our structures suggest a unique ligand-specific role of residue H142 on the alpha4 subunit. In the co-crystal structure of the mutated Ls-AChBP with the high efficacy ligand NS3920, the corresponding histidine forms an inter-subunit bridge that reinforces the ligand-mediated interactions between subunits. The structures further reveal that the binding site residues gain different and ligand-dependent interactions that could not be predicted based on wild-type Ls-AChBP structures in complex with the same agonists. The results show that an unprecedented correlation between binding in engineered AChBPs and functional receptors can be obtained and provide new opportunities for structure-based design of drugs targeting specific nAChR interfaces.
		+
		+	AChBP Engineered to Mimic the alpha4-beta4 Binding Pocket in alpha4beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity.,Shahsavar A, Ahring PK, Olsen JA, Krintel C, Kastrup JS, Balle T, Gajhede M Mol Pharmacol. 2015 Jul 15. pii: mol.115.098061. PMID:26180047<ref>PMID:26180047</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:16, 22 July 2015

2015-07-22T14:16:03Z

←Older revision		Revision as of 14:16, 22 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920==
-		+	<StructureSection load='4um3' size='340' side='right' caption='[[4um3]], [[Resolution\|resolution]] 2.70Å' scene=''>
-	~~The entry~~ 4um3 is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4um3]] is a 40 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UM3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UM3 FirstGlance]. <br>
-	~~Authors~~: ~~Shahsavar, A~~.~~, Kastrup, J~~.S.~~, Balle, T~~.~~, Gajhede, M~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=09R:1-(6-BROMOPYRIDIN-3-YL)-1,4-DIAZEPANE'>09R</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4um1\|4um1]]</td></tr>
-	~~Description~~: ~~Engineered Ls~~-~~AChBP with alpha4~~-~~alpha4 interface in complex with NS3920~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4um3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4um3 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4um3 RCSB], [http://www.ebi.ac.uk/pdbsum/4um3 PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Kastrup~~, J.S]]	+	== Function ==
-	[[~~Category~~: ~~Shahsavar, A~~]]	+	[[http://www.uniprot.org/uniprot/ACHP_LYMST ACHP_LYMST]] Binds to acetylcholine. Modulates neuronal synaptic transmission.
		+	__TOC__
		+	</StructureSection>
	[[Category: Balle, T]]		[[Category: Balle, T]]
	[[Category: Gajhede, M]]		[[Category: Gajhede, M]]
		+	[[Category: Kastrup, J S]]
		+	[[Category: Shahsavar, A]]
		+	[[Category: Cys-loop receptor]]
		+	[[Category: Ion channel]]
		+	[[Category: Nicotinic acetylcholine receptor]]
		+	[[Category: Receptor stoichiometry]]
		+	[[Category: Signaling protein]]

OCA at 18:31, 24 December 2014

2014-12-24T18:31:18Z

←Older revision		Revision as of 18:31, 24 December 2014
Line 6:		Line 6:

	Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920		Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920
		+	[[Category: Unreleased Structures]]
		+	[[Category: Kastrup, J.S]]
		+	[[Category: Shahsavar, A]]
		+	[[Category: Balle, T]]
		+	[[Category: Gajhede, M]]

OCA at 11:42, 19 November 2014

2014-11-19T11:42:18Z

←Older revision		Revision as of 11:42, 19 November 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4um3 is ON HOLD	+	The entry 4um3 is ON HOLD until Paper Publication

-	Authors: Shahsavar, A~~., Ahring, P.K., Olsen, J.A., Krintel, C~~., Kastrup, J.S., Balle, T., Gajhede, M.	+	Authors: Shahsavar, A., Kastrup, J.S., Balle, T., Gajhede, M.

	Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920		Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920

OCA at 08:35, 28 May 2014

2014-05-28T08:35:54Z

←Older revision		Revision as of 08:35, 28 May 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4um3 is ON HOLD ~~until sometime in the future~~	+	The entry 4um3 is ON HOLD

	Authors: Shahsavar, A., Ahring, P.K., Olsen, J.A., Krintel, C., Kastrup, J.S., Balle, T., Gajhede, M.		Authors: Shahsavar, A., Ahring, P.K., Olsen, J.A., Krintel, C., Kastrup, J.S., Balle, T., Gajhede, M.

	Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920		Description: Engineered Ls-AChBP with alpha4-alpha4 interface in complex with NS3920