4uoi - Revision history

OCA at 07:29, 29 March 2023

2023-03-29T07:29:40Z

←Older revision		Revision as of 07:29, 29 March 2023
Line 3:		Line 3:
	<StructureSection load='4uoi' size='340' side='right'caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>		<StructureSection load='4uoi' size='340' side='right'caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Hepatitis_c_virus_~~(~~isolate_h77~~) Hepatitis c virus (isolate ~~h77~~)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4UOI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Hepatitis_C_virus_(isolate_H77) Hepatitis C virus (isolate H77)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UOI FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [~~http~~://pdbe.org/4uoi PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4uoi PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4uoi ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [https://pdbe.org/4uoi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [https://www.ebi.ac.uk/pdbsum/4uoi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uoi ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/H9XGD6_9HEPC H9XGD6_9HEPC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Grimes~~, J M~~]]	+	[[Category: El Omari K]]
-	[[Category: Harlos, K]]	+	[[Category: Grimes JM]]
-	[[Category: Iourin, O]]	+	[[Category: Harlos K]]
-	[[Category: Kadlec, J]]	+	[[Category: Iourin O]]
-	~~[[Category: Omari, K El~~]]	+	[[Category: Kadlec J]]
-	[[Category: Stuart~~, D I]]~~	+	[[Category: Stuart DI]]
-	~~[[Category: Viral protein~~]]	+

OCA at 07:50, 3 April 2019

2019-04-03T07:50:35Z

←Older revision		Revision as of 07:50, 3 April 2019
Line 1:		Line 1:

	==Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1==		==Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1==
-	<StructureSection load='4uoi' size='340' side='right' caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>	+	<StructureSection load='4uoi' size='340' side='right'caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Hepatitis_c_virus_(isolate_h77) Hepatitis c virus (isolate h77)]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://pdbe.org/4uoi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uoi ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://pdbe.org/4uoi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uoi ProSAT]</span></td></tr>
Line 20:		Line 20:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Grimes, J M]]		[[Category: Grimes, J M]]
	[[Category: Harlos, K]]		[[Category: Harlos, K]]

OCA at 01:13, 19 January 2017

2017-01-19T01:13:13Z

←Older revision		Revision as of 01:13, 19 January 2017
Line 1:		Line 1:
		+
	==Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1==		==Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1==
	<StructureSection load='4uoi' size='340' side='right' caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>		<StructureSection load='4uoi' size='340' side='right' caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://pdbe.org/4uoi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uoi ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4uoi" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:40, 20 January 2015

2015-01-20T10:40:08Z

←Older revision		Revision as of 10:40, 20 January 2015
Line 3:		Line 3:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>
-	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum]</span></td></tr>
-	<table>	+	</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 18:		Line 18:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Grimes, J M.]]	+	[[Category: Grimes, J M]]
-	[[Category: Harlos, K.]]	+	[[Category: Harlos, K]]
-	[[Category: Iourin, O.]]	+	[[Category: Iourin, O]]
-	[[Category: Kadlec, J.]]	+	[[Category: Kadlec, J]]
-	[[Category: Omari, K El.]]	+	[[Category: Omari, K El]]
-	[[Category: Stuart, D I.]]	+	[[Category: Stuart, D I]]
	[[Category: Viral protein]]		[[Category: Viral protein]]

OCA at 16:22, 20 August 2014

2014-08-20T16:22:49Z

←Older revision		Revision as of 16:22, 20 August 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Unexpected structure for the N-terminal domain of Hepatitis C virus envelope glycoprotein E1==
		+	<StructureSection load='4uoi' size='340' side='right' caption='[[4uoi]], [[Resolution\|resolution]] 3.49Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4uoi]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UOI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UOI FirstGlance]. <br>
		+	</td></tr><tr><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene><br>
		+	<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uoi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uoi OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uoi RCSB], [http://www.ebi.ac.uk/pdbsum/4uoi PDBsum]</span></td></tr>
		+	<table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Single-wavelength anomalous dispersion of S atoms (S-SAD) is an elegant phasing method to determine crystal structures that does not require heavy-atom incorporation or selenomethionine derivatization. Nevertheless, this technique has been limited by the paucity of the signal at the usual X-ray wavelengths, requiring very accurate measurement of the anomalous differences. Here, the data collection and structure solution of the N-terminal domain of the ectodomain of HCV E1 from crystals that diffracted very weakly is reported. By combining the data from 32 crystals, it was possible to solve the sulfur substructure and calculate initial maps at 7 A resolution, and after density modication and phase extension using a higher resolution native data set to 3.5 A resolution model building was achievable.

-	~~The entry 4uoi is ON HOLD until Jun 04 2016~~	+	Pushing the limits of sulfur SAD phasing: de novo structure solution of the N-terminal domain of the ectodomain of HCV E1.,El Omari K, Iourin O, Kadlec J, Fearn R, Hall DR, Harlos K, Grimes JM, Stuart DI Acta Crystallogr D Biol Crystallogr. 2014 Aug 1;70(Pt 8):2197-203. doi:, 10.1107/S139900471401339X. Epub 2014 Jul 25. PMID:25084338<ref>PMID:25084338</ref>

-	~~Authors: El Omari~~, K.~~, Iourin, O~~.~~, Kadlec~~, J., Harlos, K., ~~Grimes~~, J.M., Stuart, D.I.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~:	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Grimes, J M.]]
		+	[[Category: Harlos, K.]]
		+	[[Category: Iourin, O.]]
		+	[[Category: Kadlec, J.]]
		+	[[Category: Omari, K El.]]
		+	[[Category: Stuart, D I.]]
		+	[[Category: Viral protein]]

OCA at 09:59, 16 July 2014

2014-07-16T09:59:30Z

←Older revision		Revision as of 09:59, 16 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4uoi is ON HOLD	+	The entry 4uoi is ON HOLD until Jun 04 2016

	Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.		Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.

	Description:		Description:

OCA at 07:01, 9 July 2014

2014-07-09T07:01:45Z

←Older revision		Revision as of 07:01, 9 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4uoi is ON HOLD ~~until sometime in the future~~	+	The entry 4uoi is ON HOLD

	Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.		Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.

	Description:		Description:

OCA at 07:36, 2 July 2014

2014-07-02T07:36:31Z

←Older revision		Revision as of 07:36, 2 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4uoi is ON HOLD	+	The entry 4uoi is ON HOLD until sometime in the future

	Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.		Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.

	Description:		Description:

OCA: Protected "4uoi" [edit=sysop:move=sysop]

2014-06-11T08:18:37Z

Protected "4uoi" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:18, 11 June 2014

OCA: New page: '''Unreleased structure''' The entry 4uoi is ON HOLD Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I. Description:

2014-06-11T08:18:35Z

New page: '''Unreleased structure''' The entry 4uoi is ON HOLD Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I. Description:

New page

'''Unreleased structure'''

The entry 4uoi is ON HOLD

Authors: El Omari, K., Iourin, O., Kadlec, J., Harlos, K., Grimes, J.M., Stuart, D.I.

Description: