4uqu - Revision history

OCA at 11:22, 9 May 2024

2024-05-09T11:22:20Z

←Older revision		Revision as of 11:22, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UQU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UQU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.595Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [https://pdbe.org/4uqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [https://www.ebi.ac.uk/pdbsum/4uqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqu ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [https://pdbe.org/4uqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [https://www.ebi.ac.uk/pdbsum/4uqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqu ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:33, 29 March 2023

2023-03-29T07:33:01Z

←Older revision		Revision as of 07:33, 29 March 2023
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	==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==		==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==
-	<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>	+	<StructureSection load='4uqu' size='340' side='right'caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4UQU FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4UQU FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ur0\|4ur0]], [[4ur1\|4ur1]], [[4ur2\|4ur2]], [[4ur3\|4ur3]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [https://pdbe.org/4uqu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [https://www.ebi.ac.uk/pdbsum/4uqu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqu ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tetrachloroethene_reductive_dehalogenase Tetrachloroethene reductive dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.8 1.97.1.8] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [~~http~~://pdbe.org/4uqu PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4uqu PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqu ProSAT]</span></td></tr>	+
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	==See Also==		==See Also==
-	*[[Dehalogenase\|Dehalogenase]]	+	*[[Dehalogenase 3D structures\|Dehalogenase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Sulfurospirillum multivorans]]		[[Category: Sulfurospirillum multivorans]]
-	~~[[Category: Tetrachloroethene reductive dehalogenase]]~~	+	[[Category: Bommer M]]
-	[[Category: Bommer, M]]	+	[[Category: Diekert G]]
-	[[Category: Diekert, G]]	+	[[Category: Dobbek H]]
-	[[Category: Dobbek, H]]	+	[[Category: Fesseler J]]
-	[[Category: Fesseler, J]]	+	[[Category: Kunze C]]
-	[[Category: Kunze, C]]	+	[[Category: Schubert T]]
-	[[Category: Schubert, T]]	+
-	~~[[Category: Organohalide respiration]]~~	+
-	~~[[Category: Oxidoreductase~~]]	+

OCA at 08:11, 6 March 2019

2019-03-06T08:11:04Z

←Older revision		Revision as of 08:11, 6 March 2019
Line 1:		Line 1:

	==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==		==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==
-	<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>	+	<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UQU FirstGlance]. <br>		<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UQU FirstGlance]. <br>

OCA at 08:56, 11 August 2016

2016-08-11T08:56:46Z

←Older revision		Revision as of 08:56, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==		==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==
	<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>		<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ur0\|4ur0]], [[4ur1\|4ur1]], [[4ur2\|4ur2]], [[4ur3\|4ur3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ur0\|4ur0]], [[4ur1\|4ur1]], [[4ur2\|4ur2]], [[4ur3\|4ur3]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tetrachloroethene_reductive_dehalogenase Tetrachloroethene reductive dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.8 1.97.1.8] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tetrachloroethene_reductive_dehalogenase Tetrachloroethene reductive dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.8 1.97.1.8] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [http://www.ebi.ac.uk/pdbsum/4uqu PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [http://pdbe.org/4uqu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [http://www.ebi.ac.uk/pdbsum/4uqu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4uqu ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4uqu" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Dehalogenase\|Dehalogenase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:09, 25 January 2015

2015-01-25T10:09:07Z

←Older revision		Revision as of 10:09, 25 January 2015
Line 22:		Line 22:
	[[Category: Sulfurospirillum multivorans]]		[[Category: Sulfurospirillum multivorans]]
	[[Category: Tetrachloroethene reductive dehalogenase]]		[[Category: Tetrachloroethene reductive dehalogenase]]
-	[[Category: Bommer, M.]]	+	[[Category: Bommer, M]]
-	[[Category: Diekert, G.]]	+	[[Category: Diekert, G]]
-	[[Category: Dobbek, H.]]	+	[[Category: Dobbek, H]]
-	[[Category: Fesseler, J.]]	+	[[Category: Fesseler, J]]
-	[[Category: Kunze, C.]]	+	[[Category: Kunze, C]]
-	[[Category: Schubert, T.]]	+	[[Category: Schubert, T]]
	[[Category: Organohalide respiration]]		[[Category: Organohalide respiration]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 10:47, 20 October 2014

2014-10-20T10:47:04Z

←Older revision		Revision as of 10:47, 20 October 2014
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans==
		+	<StructureSection load='4uqu' size='340' side='right' caption='[[4uqu]], [[Resolution\|resolution]] 1.59Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4uqu]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Sulfurospirillum_multivorans Sulfurospirillum multivorans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UQU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UQU FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BEN:BENZAMIDINE'>BEN</scene>, <scene name='pdbligand=BVQ:NORPSEUDO-B12'>BVQ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ur0\|4ur0]], [[4ur1\|4ur1]], [[4ur2\|4ur2]], [[4ur3\|4ur3]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Tetrachloroethene_reductive_dehalogenase Tetrachloroethene reductive dehalogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.97.1.8 1.97.1.8] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4uqu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4uqu OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4uqu RCSB], [http://www.ebi.ac.uk/pdbsum/4uqu PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Organohalide-respiring microorganisms can use a variety of persistent pollutants including trichloroethene (TCE) as terminal electron acceptors. The final two-electron transfer step in organohalide respiration is catalyzed by reductive dehalogenases. Here we report the x-ray crystal structure of PceA, an archetypal dehalogenase from Sulfurospirillum multivorans, as well as structures of PceA in complex with TCE and product analogs. The active site harbors a deeply buried norpseudo-B12 cofactor within a nitroreductase fold, also found in a mammalian B12 chaperone. The structures of PceA reveal how a cobalamin supports a reductive haloelimination exploiting a conserved B12-binding scaffold capped by a highly variable substrate-capturing region.

-	~~The entry 4uqu is ON HOLD until Paper Publication~~	+	Structural basis for organohalide respiration.,Bommer M, Kunze C, Fesseler J, Schubert T, Diekert G, Dobbek H Science. 2014 Oct 2. pii: 1258118. PMID:25278505<ref>PMID:25278505</ref>

-	~~Authors~~: Bommer, M., ~~Kunze, C~~., Fesseler, J., Schubert, T.~~, Diekert, G., Dobbek, H.~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans~~	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Sulfurospirillum multivorans]]
		+	[[Category: Tetrachloroethene reductive dehalogenase]]
		+	[[Category: Bommer, M.]]
		+	[[Category: Diekert, G.]]
		+	[[Category: Dobbek, H.]]
		+	[[Category: Fesseler, J.]]
		+	[[Category: Kunze, C.]]
		+	[[Category: Schubert, T.]]
		+	[[Category: Organohalide respiration]]
		+	[[Category: Oxidoreductase]]

OCA at 10:00, 16 July 2014

2014-07-16T10:00:00Z

←Older revision		Revision as of 10:00, 16 July 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4uqu is ON HOLD	+	The entry 4uqu is ON HOLD until Paper Publication

	Authors: Bommer, M., Kunze, C., Fesseler, J., Schubert, T., Diekert, G., Dobbek, H.		Authors: Bommer, M., Kunze, C., Fesseler, J., Schubert, T., Diekert, G., Dobbek, H.

	Description: Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans		Description: Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans

OCA: Protected "4uqu" [edit=sysop:move=sysop]

2014-07-02T07:38:15Z

Protected "4uqu" [edit=sysop:move=sysop]

←Older revision

Revision as of 07:38, 2 July 2014

OCA: New page: '''Unreleased structure''' The entry 4uqu is ON HOLD Authors: Bommer, M., Kunze, C., Fesseler, J., Schubert, T., Diekert, G., Dobbek, H. Description: Crystal structure of the tetrachlo...

2014-07-02T07:38:14Z

New page: '''Unreleased structure''' The entry 4uqu is ON HOLD Authors: Bommer, M., Kunze, C., Fesseler, J., Schubert, T., Diekert, G., Dobbek, H. Description: Crystal structure of the tetrachlo...

New page

'''Unreleased structure'''

The entry 4uqu is ON HOLD

Authors: Bommer, M., Kunze, C., Fesseler, J., Schubert, T., Diekert, G., Dobbek, H.

Description: Crystal structure of the tetrachloroethene reductive dehalogenase from Sulfurospirillum multivorans