4wd1 - Revision history

OCA at 07:29, 27 September 2023

2023-09-27T07:29:42Z

←Older revision		Revision as of 07:29, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lividans_TK24 Streptomyces lividans TK24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lividans_TK24 Streptomyces lividans TK24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.903Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [https://pdbe.org/4wd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [https://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [https://pdbe.org/4wd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [https://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:02, 7 April 2023

2023-04-07T07:02:53Z

←Older revision		Revision as of 07:02, 7 April 2023
Line 3:		Line 3:
	<StructureSection load='4wd1' size='340' side='right'caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4wd1' size='340' side='right'caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Streptomyces_lividans_tk24~~ Streptomyces lividans ~~tk24~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lividans_TK24 Streptomyces lividans TK24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSPG_06161 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=457428 Streptomyces lividans TK24])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [https://pdbe.org/4wd1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [https://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [~~http~~://pdbe.org/4wd1 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/D6EQU8_STRLI D6EQU8_STRLI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 22:		Line 23:
	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Streptomyces lividans ~~tk24~~]]	+	[[Category: Streptomyces lividans TK24]]
-	[[Category: Gulick~~, A M~~]]	+	[[Category: Gulick AM]]
-	[[Category: Mitchell~~, C A]]~~	+	[[Category: Mitchell CA]]
-	~~[[Category: Adenylate-forming enzyme]]~~	+
-	~~[[Category: Anl superfamily]]~~	+
-	~~[[Category: Ligase~~]]	+

OCA at 10:28, 25 December 2019

2019-12-25T10:28:59Z

←Older revision		Revision as of 10:28, 25 December 2019
Line 1:		Line 1:

	==Acetoacetyl-CoA Synthetase from Streptomyces lividans==		==Acetoacetyl-CoA Synthetase from Streptomyces lividans==
-	<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='4wd1' size='340' side='right'caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans_tk24 Streptomyces lividans tk24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans_tk24 Streptomyces lividans tk24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
Line 21:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Streptomyces lividans tk24]]		[[Category: Streptomyces lividans tk24]]
	[[Category: Gulick, A M]]		[[Category: Gulick, A M]]

OCA at 15:10, 15 November 2017

2017-11-15T15:10:15Z

←Older revision		Revision as of 15:10, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_lividans_tk24 Streptomyces lividans tk24]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">SSPG_06161 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=457428 Streptomyces lividans TK24])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [http://pdbe.org/4wd1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [http://pdbe.org/4wd1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Streptomyces lividans tk24]]
	[[Category: Gulick, A M]]		[[Category: Gulick, A M]]
	[[Category: Mitchell, C A]]		[[Category: Mitchell, C A]]
	[[Category: Adenylate-forming enzyme]]		[[Category: Adenylate-forming enzyme]]
	[[Category: Anl superfamily]]		[[Category: Anl superfamily]]
		+	[[Category: Ligase]]

OCA at 00:12, 26 January 2017

2017-01-26T00:12:13Z

←Older revision		Revision as of 00:12, 26 January 2017
Line 1:		Line 1:
		+
	==Acetoacetyl-CoA Synthetase from Streptomyces lividans==		==Acetoacetyl-CoA Synthetase from Streptomyces lividans==
	<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4wd1 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [http://pdbe.org/4wd1 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4wd1 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wd1 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 14:		Line 15:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wd1" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:36, 28 January 2015

2015-01-28T16:36:15Z

←Older revision		Revision as of 16:36, 28 January 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Acetoacetyl-CoA Synthetase from Streptomyces lividans==
		+	<StructureSection load='4wd1' size='340' side='right' caption='[[4wd1]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4wd1]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WD1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WD1 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wd1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wd1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wd1 RCSB], [http://www.ebi.ac.uk/pdbsum/4wd1 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The adenosine monoposphate-forming acyl-CoA synthetase enzymes catalyze a two-step reaction that involves the initial formation of an acyl adenylate that reacts in a second partial reaction to form a thioester between the acyl substrate and CoA. These enzymes utilize a Domain Alternation catalytic mechanism, whereby a approximately 110 residue C-terminal domain rotates by 140 degrees to form distinct catalytic conformations for the two partial reactions. The structure of an acetoacetyl-CoA synthetase (AacS) is presented that illustrates a novel aspect of this C-terminal domain. Specifically, several acetyl- and acetoacetyl-CoA synthetases contain a 30-residue extension on the C-terminus compared to other members of this family. Whereas residues from this extension are disordered in prior structures, the AacS structure shows that residues from this extension may interact with key catalytic residues from the N-terminal domain. Proteins 2014. (c) 2014 Wiley Periodicals, Inc.

-	The ~~entry 4wd1 is ON HOLD until Paper Publication~~	+	The structure of S. lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain.,Mitchell CA, Tucker AC, Escalante-Semerena JC, Gulick AM Proteins. 2014 Dec 9. doi: 10.1002/prot.24738. PMID:25488501<ref>PMID:25488501</ref>

-	~~Authors: Gulick~~, A.M.~~, Mitchell, C.A~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: Mitchell, C.A]]	+	__TOC__
-	[[Category: ~~Gulick, A.M~~]]	+	</StructureSection>
		+	[[Category: Gulick, A M]]
		+	[[Category: Mitchell, C A]]
		+	[[Category: Adenylate-forming enzyme]]
		+	[[Category: Anl superfamily]]

OCA at 19:20, 24 December 2014

2014-12-24T19:20:55Z

←Older revision		Revision as of 19:20, 24 December 2014
Line 6:		Line 6:

	Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans		Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans
		+	[[Category: Unreleased Structures]]
		+	[[Category: Mitchell, C.A]]
		+	[[Category: Gulick, A.M]]

OCA at 06:52, 8 October 2014

2014-10-08T06:52:39Z

←Older revision		Revision as of 06:52, 8 October 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4wd1 is ON HOLD	+	The entry 4wd1 is ON HOLD until Paper Publication

	Authors: Gulick, A.M., Mitchell, C.A.		Authors: Gulick, A.M., Mitchell, C.A.

	Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans		Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans

OCA: Protected "4wd1" [edit=sysop:move=sysop]

2014-09-24T09:09:00Z

Protected "4wd1" [edit=sysop:move=sysop]

←Older revision

Revision as of 09:09, 24 September 2014

OCA: New page: '''Unreleased structure''' The entry 4wd1 is ON HOLD Authors: Gulick, A.M., Mitchell, C.A. Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans

2014-09-24T09:08:59Z

New page: '''Unreleased structure''' The entry 4wd1 is ON HOLD Authors: Gulick, A.M., Mitchell, C.A. Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans

New page

'''Unreleased structure'''

The entry 4wd1 is ON HOLD

Authors: Gulick, A.M., Mitchell, C.A.

Description: Acetoacetyl-CoA Synthetase from Streptomyces lividans