4wql - Revision history

OCA at 00:55, 28 December 2023

2023-12-28T00:55:03Z

←Older revision		Revision as of 00:55, 28 December 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.73Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [https://pdbe.org/4wql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [https://www.ebi.ac.uk/pdbsum/4wql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wql ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [https://pdbe.org/4wql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [https://www.ebi.ac.uk/pdbsum/4wql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wql ProSAT]</span></td></tr>
	</table>		</table>

OCA at 07:21, 7 April 2023

2023-04-07T07:21:13Z

←Older revision		Revision as of 07:21, 7 April 2023
Line 1:		Line 1:

	==Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound==		==Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound==
-	<StructureSection load='4wql' size='340' side='right' caption='[[4wql]], [[Resolution\|resolution]] 1.73Å' scene=''>	+	<StructureSection load='4wql' size='340' side='right'caption='[[4wql]], [[Resolution\|resolution]] 1.73Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WQL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WQL FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wqk\|4wqk]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [https://pdbe.org/4wql PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [https://www.ebi.ac.uk/pdbsum/4wql PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wql ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [~~http~~://pdbe.org/4wql PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wql PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wql ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN]] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.	+	[https://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Transferase~~]]	+	[[Category: Klebsiella pneumoniae]]
-	[[Category: ~~Anderson, W F~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Structural genomic~~]]	+	[[Category: Anderson WF]]
-	[[Category: Cox, G]]	+	[[Category: Cox G]]
-	[[Category: Savchenko, A]]	+	[[Category: Savchenko A]]
-	[[Category: Stogios~~, P J~~]]	+	[[Category: Stogios PJ]]
-	[[Category: Wright~~, G D]]~~	+	[[Category: Wright GD]]
-	~~[[Category: Adenylyltransferase]]~~	+
-	~~[[Category: Alpha/beta protein]]~~	+
-	~~[[Category: Aminoglycoside]]~~	+
-	~~[[Category: Antibiotic resistance]]~~	+
-	~~[[Category: Csgid]]~~	+
-	~~[[Category: Kanamycin]]~~	+
-	~~[[Category: National institute of allergy and infectious disease]]~~	+
-	~~[[Category: Niaid]]~~	+
-	~~[[Category: Nucleotidyltransferase fold]]~~	+
-	~~[[Category: Nucleotidylyltransferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 07:13, 9 March 2017

2017-03-09T07:13:17Z

←Older revision		Revision as of 07:13, 9 March 2017
Line 25:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Transferase]]		[[Category: Transferase]]
		+	[[Category: Anderson, W F]]
	[[Category: Structural genomic]]		[[Category: Structural genomic]]
	[[Category: Cox, G]]		[[Category: Cox, G]]

OCA at 14:27, 11 August 2016

2016-08-11T14:27:04Z

←Older revision		Revision as of 14:27, 11 August 2016
Line 1:		Line 1:
		+
	==Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound==		==Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound==
	<StructureSection load='4wql' size='340' side='right' caption='[[4wql]], [[Resolution\|resolution]] 1.73Å' scene=''>		<StructureSection load='4wql' size='340' side='right' caption='[[4wql]], [[Resolution\|resolution]] 1.73Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wqk\|4wqk]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wqk\|4wqk]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [http://www.ebi.ac.uk/pdbsum/4wql PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [http://pdbe.org/4wql PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [http://www.ebi.ac.uk/pdbsum/4wql PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wql ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wql" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 10:55, 28 January 2015

2015-01-28T10:55:07Z

←Older revision		Revision as of 10:55, 28 January 2015
Line 10:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN]] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.		[[http://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN]] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The aminoglycosides are highly effective broad-spectrum antimicrobial agents. However, their efficacy is diminished due to enzyme-mediated covalent modification, which reduces affinity of the drug for the target ribosome. One of the most prevalent aminoglycoside resistance enzymes in Gram-negative pathogens is the adenylyltransferase ANT(2'')-Ia, which confers resistance to gentamicin, tobramycin, and kanamycin. Despite the importance of this enzyme in drug resistance, its structure and molecular mechanism have been elusive. This study describes the structural and mechanistic basis for adenylylation of aminoglycosides by the ANT(2'')-Ia enzyme. ANT(2'')-Ia confers resistance by magnesium-dependent transfer of a nucleoside monophosphate (AMP) to the 2''-hydroxyl of aminoglycoside substrates containing a 2-deoxystreptamine core. The catalyzed reaction follows a direct AMP transfer mechanism from ATP to the substrate antibiotic. Central to catalysis is the coordination of two Mg(2+) ions, positioning of the modifiable substrate ring, and the presence of a catalytic base (Asp86). Comparative structural analysis revealed that ANT(2'')-Ia has a two-domain structure with an N-terminal active-site architecture that is conserved among other antibiotic nucleotidyltransferases, including Lnu(A), LinB, ANT(4')-Ia, ANT(4'')-Ib, and ANT(6)-Ia. There is also similarity between the nucleotidyltransferase fold of ANT(2'')-Ia and DNA polymerase beta. This similarity is consistent with evolution from a common ancestor, with the nucleotidyltransferase fold having adapted for activity against chemically distinct molecules. IMPORTANCE : To successfully manage the threat associated with multidrug-resistant infectious diseases, innovative therapeutic strategies need to be developed. One such approach involves the enhancement or potentiation of existing antibiotics against resistant strains of bacteria. The reduction in clinical usefulness of the aminoglycosides is a particular problem among Gram-negative human pathogens, since there are very few therapeutic options for infections caused by these organisms. In order to successfully circumvent or inhibit the activity of aminoglycoside-modifying enzymes, and to thus rejuvenate the activity of the aminoglycoside antibiotics against Gram-negative pathogens, structural and mechanistic information is crucial. This study reveals the structure of a clinically prevalent aminoglycoside resistance enzyme [ANT(2'')-Ia] and depicts the molecular basis underlying modification of antibiotic substrates. Combined, these findings provide the groundwork for the development of broad-spectrum inhibitors against antibiotic nucleotidyltransferases.
		+
		+	Structural and Molecular Basis for Resistance to Aminoglycoside Antibiotics by the Adenylyltransferase ANT(2'')-Ia.,Cox G, Stogios PJ, Savchenko A, Wright GD MBio. 2015 Jan 6;6(1). pii: e02180-14. doi: 10.1128/mBio.02180-14. PMID:25564464<ref>PMID:25564464</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:32, 24 December 2014

2014-12-24T11:32:46Z

←Older revision		Revision as of 11:32, 24 December 2014
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQL FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQL FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4wqk\|4wqk]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [http://www.ebi.ac.uk/pdbsum/4wql PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [http://www.ebi.ac.uk/pdbsum/4wql PDBsum]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/AADB1_KLEPN AADB1_KLEPN]] This enzyme confers resistance to kanamycin, gentamicin, dibekacin, sisomicin and tobramycin by adenylating the 2''-hydroxyl group of these antibiotics.
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 07:05, 12 November 2014

2014-11-12T07:05:08Z

←Older revision		Revision as of 07:05, 12 November 2014
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2")-Ia, kanamycin-bound==
-		+	<StructureSection load='4wql' size='340' side='right' caption='[[4wql]], [[Resolution\|resolution]] 1.73Å' scene=''>
-	~~The entry~~ 4wql is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4wql]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WQL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WQL FirstGlance]. <br>
-	~~Authors~~: ~~Cox~~, G., ~~Stogios~~, P.J., Savchenko, A., Wright, G.D~~., Center for Structural Genomics of Infectious Diseases (CSGID)~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=KAN:KANAMYCIN+A'>KAN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.46 2.7.7.46] </span></td></tr>
-	~~Description~~: ~~Crystal structure~~ of ~~aminoglycoside nucleotidylyltransferase ANT(2"")~~-~~Ia, kanamycin-bound~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wql FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wql OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wql RCSB], [http://www.ebi.ac.uk/pdbsum/4wql PDBsum]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Transferase]]
		+	[[Category: Structural genomic]]
		+	[[Category: Cox, G]]
		+	[[Category: Savchenko, A]]
		+	[[Category: Stogios, P J]]
		+	[[Category: Wright, G D]]
		+	[[Category: Adenylyltransferase]]
		+	[[Category: Alpha/beta protein]]
		+	[[Category: Aminoglycoside]]
		+	[[Category: Antibiotic resistance]]
		+	[[Category: Csgid]]
		+	[[Category: Kanamycin]]
		+	[[Category: National institute of allergy and infectious disease]]
		+	[[Category: Niaid]]
		+	[[Category: Nucleotidyltransferase fold]]
		+	[[Category: Nucleotidylyltransferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA: Protected "4wql" [edit=sysop:move=sysop]

2014-10-29T10:35:38Z

Protected "4wql" [edit=sysop:move=sysop]

←Older revision

Revision as of 10:35, 29 October 2014

OCA: New page: '''Unreleased structure''' The entry 4wql is ON HOLD Authors: Cox, G., Stogios, P.J., Savchenko, A., Wright, G.D., Center for Structural Genomics of Infectious Diseases (CSGID) Descrip...

2014-10-29T10:35:37Z

New page: '''Unreleased structure''' The entry 4wql is ON HOLD Authors: Cox, G., Stogios, P.J., Savchenko, A., Wright, G.D., Center for Structural Genomics of Infectious Diseases (CSGID) Descrip...

New page

'''Unreleased structure'''

The entry 4wql is ON HOLD

Authors: Cox, G., Stogios, P.J., Savchenko, A., Wright, G.D., Center for Structural Genomics of Infectious Diseases (CSGID)

Description: Crystal structure of aminoglycoside nucleotidylyltransferase ANT(2"")-Ia, kanamycin-bound