4wws - Revision history

OCA at 07:38, 27 September 2023

2023-09-27T07:38:09Z

←Older revision		Revision as of 07:38, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WWS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WWS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [https://pdbe.org/4wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [https://www.ebi.ac.uk/pdbsum/4wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [https://pdbe.org/4wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [https://www.ebi.ac.uk/pdbsum/4wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>
	</table>		</table>

OCA at 21:01, 12 April 2023

2023-04-12T21:01:02Z

←Older revision		Revision as of 21:01, 12 April 2023
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	==Structure of Chlorite dismutase-like Protein from Listeria monocytogenes==		==Structure of Chlorite dismutase-like Protein from Listeria monocytogenes==
-	<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='4wws' size='340' side='right'caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Lismo Lismo~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4WWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Listeria_monocytogenes_EGD-e Listeria monocytogenes EGD-e]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4WWS FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lmo2113 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=169963 LISMO])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [https://pdbe.org/4wws PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [https://www.ebi.ac.uk/pdbsum/4wws PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [~~http~~://pdbe.org/4wws PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4wws PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~Y2113_LISMO Y2113_LISMO~~]~~] May function as heme~~-dependent ~~peroxidase~~.	+	[https://www.uniprot.org/uniprot/CHDC_LISMO CHDC_LISMO] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:27758026, PubMed:31423350). Catalyzes the decarboxylation of Fe-coproporphyrin III (coproheme) to heme b (protoheme IX), the last step of the pathway (PubMed:27758026, PubMed:31423350, PubMed:29536725). The reaction occurs in a stepwise manner with a three-propionate intermediate (PubMed:27758026, PubMed:31423350).<ref>PMID:27758026</ref> <ref>PMID:29536725</ref> <ref>PMID:31423350</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Lismo~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Djinovic~~-~~Carugo, K~~]]	+	[[Category: Listeria monocytogenes EGD-e]]
-	[[Category: ~~Hagmueller, A]]~~	+	[[Category: Djinovic-Carugo K]]
-	~~[[Category: Mlynek, G]]~~	+	[[Category: Hagmueller A]]
-	~~[[Category: Chlorite dismutase~~-~~like protein~~]]	+	[[Category: Mlynek G]]
-	[[Category: ~~Ferredoxin-like fold~~]]	+
-	[[Category: ~~Oxidoreductase~~]]	+

OCA at 09:05, 1 November 2017

2017-11-01T09:05:35Z

←Older revision		Revision as of 09:05, 1 November 2017
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	<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WWS FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Lismo Lismo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WWS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">lmo2113 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=169963 LISMO])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [http://pdbe.org/4wws PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [http://www.ebi.ac.uk/pdbsum/4wws PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [http://pdbe.org/4wws PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [http://www.ebi.ac.uk/pdbsum/4wws PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>
	</table>		</table>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Lismo]]
	[[Category: Djinovic-Carugo, K]]		[[Category: Djinovic-Carugo, K]]
	[[Category: Hagmueller, A]]		[[Category: Hagmueller, A]]

OCA at 05:33, 9 September 2016

2016-09-09T05:33:01Z

←Older revision		Revision as of 05:33, 9 September 2016
Line 1:		Line 1:
		+
	==Structure of Chlorite dismutase-like Protein from Listeria monocytogenes==		==Structure of Chlorite dismutase-like Protein from Listeria monocytogenes==
	<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WWS FirstGlance]. <br>		<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WWS FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [http://www.ebi.ac.uk/pdbsum/4wws PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [http://pdbe.org/4wws PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [http://www.ebi.ac.uk/pdbsum/4wws PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4wws ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 16:		Line 17:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4wws" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Djinovic-Carugo, K]]
	[[Category: Hagmueller, A]]		[[Category: Hagmueller, A]]
		+	[[Category: Mlynek, G]]
	[[Category: Chlorite dismutase-like protein]]		[[Category: Chlorite dismutase-like protein]]
	[[Category: Ferredoxin-like fold]]		[[Category: Ferredoxin-like fold]]
	[[Category: Oxidoreductase]]		[[Category: Oxidoreductase]]

OCA at 15:46, 7 February 2015

2015-02-07T15:46:22Z

←Older revision		Revision as of 15:46, 7 February 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Structure of Chlorite dismutase-like Protein from Listeria monocytogenes==
		+	<StructureSection load='4wws' size='340' side='right' caption='[[4wws]], [[Resolution\|resolution]] 2.00Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4wws]] is a 5 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WWS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WWS FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wws FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wws OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wws RCSB], [http://www.ebi.ac.uk/pdbsum/4wws PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/Y2113_LISMO Y2113_LISMO]] May function as heme-dependent peroxidase.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Chlorite dismutase-like proteins are structurally closely related to functional chlorite dismutases which are heme b-dependent oxidoreductases capable of reducing chlorite to chloride with simultaneous production of dioxygen. Chlorite dismutase-like proteins are incapable of performing this reaction and their biological role is still under discussion. Recently, members of this large protein family were shown to be involved in heme biosynthesis in Gram-positive bacteria, and thus the protein was renamed HemQ in these organisms. In the present work the structural and heme binding properties of the chlorite dismutase-like protein from the Gram-positive pathogen Listeria monocytogenes (LmCld) were analyzed in order to evaluate its potential role as a regulatory heme sensing protein. The homopentameric crystal structure (2.0A) shows high similarity to chlorite-degrading chlorite dismutases with an important difference in the structure of the putative substrate and heme entrance channel. In solution LmCld is a stable hexamer able to bind the low-spin ligand cyanide. Heme binding is reversible with KD-values determined to be 7.2muM (circular dichroism spectroscopy) and 16.8muM (isothermal titration calorimetry) at pH 7.0. Both acidic and alkaline conditions promote heme release. Presented biochemical and structural data reveal that the chlorite dismutase-like protein from L. monocytogenes could act as a potential regulatory heme sensing and storage protein within heme biosynthesis.

-	~~The entry 4wws is ON HOLD until Paper Publication~~	+	Structure and heme-binding properties of HemQ (chlorite dismutase-like protein) from Listeria monocytogenes.,Hofbauer S, Hagmuller A, Schaffner I, Mlynek G, Krutzler M, Stadlmayr G, Pirker KF, Obinger C, Daims H, Djinovic-Carugo K, Furtmuller PG Arch Biochem Biophys. 2015 Jan 17. pii: S0003-9861(15)00026-0. doi:, 10.1016/j.abb.2015.01.010. PMID:25602700<ref>PMID:25602700</ref>

-	~~Authors: Hagmueller~~, A.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Structure of Chlorite dismutase-like Protein from Listeria monocytogenes~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Hagmueller, A]]		[[Category: Hagmueller, A]]
		+	[[Category: Chlorite dismutase-like protein]]
		+	[[Category: Ferredoxin-like fold]]
		+	[[Category: Oxidoreductase]]

OCA at 20:07, 24 December 2014

2014-12-24T20:07:32Z

←Older revision		Revision as of 20:07, 24 December 2014
Line 6:		Line 6:

	Description: Structure of Chlorite dismutase-like Protein from Listeria monocytogenes		Description: Structure of Chlorite dismutase-like Protein from Listeria monocytogenes
		+	[[Category: Unreleased Structures]]
		+	[[Category: Hagmueller, A]]

OCA at 07:11, 26 November 2014

2014-11-26T07:11:04Z

←Older revision		Revision as of 07:11, 26 November 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4wws is ON HOLD	+	The entry 4wws is ON HOLD until Paper Publication

	Authors: Hagmueller, A.		Authors: Hagmueller, A.

-	Description: Structure of Chlorite dismutase-like ~~enzyme~~ from Listeria monocytogenes	+	Description: Structure of Chlorite dismutase-like Protein from Listeria monocytogenes

OCA: Protected "4wws" [edit=sysop:move=sysop]

2014-11-19T12:01:38Z

Protected "4wws" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:01, 19 November 2014

OCA: New page: '''Unreleased structure''' The entry 4wws is ON HOLD Authors: Hagmueller, A. Description: Structure of Chlorite dismutase-like enzyme from Listeria monocytogenes

2014-11-19T12:01:36Z

New page: '''Unreleased structure''' The entry 4wws is ON HOLD Authors: Hagmueller, A. Description: Structure of Chlorite dismutase-like enzyme from Listeria monocytogenes

New page

'''Unreleased structure'''

The entry 4wws is ON HOLD

Authors: Hagmueller, A.

Description: Structure of Chlorite dismutase-like enzyme from Listeria monocytogenes