4x30 - Revision history

OCA at 15:24, 8 November 2023

2023-11-08T15:24:43Z

←Older revision		Revision as of 15:24, 8 November 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X30 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X30 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.55Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [https://pdbe.org/4x30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [https://www.ebi.ac.uk/pdbsum/4x30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x30 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [https://pdbe.org/4x30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [https://www.ebi.ac.uk/pdbsum/4x30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x30 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 21:08, 12 April 2023

2023-04-12T21:08:48Z

←Older revision		Revision as of 21:08, 12 April 2023
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	<StructureSection load='4x30' size='340' side='right'caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4x30' size='340' side='right'caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4X30 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4X30 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [~~http~~://pdbe.org/4x30 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4x30 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4x30 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [https://pdbe.org/4x30 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [https://www.ebi.ac.uk/pdbsum/4x30 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4x30 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:[~~http~~://omim.org/entry/314200 314200]]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid.	+	[https://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:[https://omim.org/entry/314200 314200]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum.	+	[https://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN] Major thyroid hormone transport protein in serum.

	==See Also==		==See Also==
Line 16:		Line 16:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Qi, X]]	+	[[Category: Qi X]]
-	~~[[Category: Cation pi interaction]]~~	+
-	~~[[Category: Hormone release]]~~	+
-	~~[[Category: Serpin]]~~	+
-	~~[[Category: Tbg]]~~	+
-	~~[[Category: Thyroxine]]~~	+
-	~~[[Category: Thyroxine-binding globulin]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 07:59, 4 March 2020

2020-03-04T07:59:02Z

←Older revision		Revision as of 07:59, 4 March 2020
Line 1:		Line 1:

	==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution==		==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution==
-	<StructureSection load='4x30' size='340' side='right' caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>	+	<StructureSection load='4x30' size='340' side='right'caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum.		[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum.
		+
		+	==See Also==
		+	*[[Serpin 3D structures\|Serpin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Qi, X]]		[[Category: Qi, X]]
	[[Category: Cation pi interaction]]		[[Category: Cation pi interaction]]

OCA at 09:54, 18 October 2017

2017-10-18T09:54:38Z

←Older revision		Revision as of 09:54, 18 October 2017
Line 1:		Line 1:
		+
	==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution==		==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution==
	<StructureSection load='4x30' size='340' side='right' caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>		<StructureSection load='4x30' size='340' side='right' caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [http://pdbe.org/4x30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [http://www.ebi.ac.uk/pdbsum/4x30 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [http://pdbe.org/4x30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [http://www.ebi.ac.uk/pdbsum/4x30 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4x30 ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==

OCA at 16:15, 2 December 2015

2015-12-02T16:15:20Z

←Older revision		Revision as of 16:15, 2 December 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution==
-		+	<StructureSection load='4x30' size='340' side='right' caption='[[4x30]], [[Resolution\|resolution]] 1.55Å' scene=''>
-	~~The entry~~ 4x30 is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4x30]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X30 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X30 FirstGlance]. <br>
-	~~Authors~~: Qi, X.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=F:FLUORIDE+ION'>F</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=T44:3,5,3,5-TETRAIODO-L-THYRONINE'>T44</scene></td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x30 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x30 OCA], [http://pdbe.org/4x30 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4x30 RCSB], [http://www.ebi.ac.uk/pdbsum/4x30 PDBsum]</span></td></tr>
-	~~Description~~: ~~Crystal structure~~ of ~~human Thyroxine~~-binding globulin ~~complexed with thyroine at 1~~.~~55 Angstrom resolution~~	+	</table>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Defects in SERPINA7 are a cause of thyroxine-binding globulin deficiency (TBG deficiency) [MIM:[http://omim.org/entry/314200 314200]]. Mutations in the SERPINA7 gene can result as a whole spectrum of deficiencies, characterized by either reduced or increased TBG levels in the serum. Patients show, respectively, reduced or elevated protein-bound iodine but are euthyroid.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/THBG_HUMAN THBG_HUMAN]] Major thyroid hormone transport protein in serum.
		+	__TOC__
		+	</StructureSection>
	[[Category: Qi, X]]		[[Category: Qi, X]]
		+	[[Category: Cation pi interaction]]
		+	[[Category: Hormone release]]
		+	[[Category: Serpin]]
		+	[[Category: Tbg]]
		+	[[Category: Thyroxine]]
		+	[[Category: Thyroxine-binding globulin]]
		+	[[Category: Transport protein]]

OCA at 20:23, 24 December 2014

2014-12-24T20:23:27Z

←Older revision		Revision as of 20:23, 24 December 2014
Line 6:		Line 6:

	Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution		Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution
		+	[[Category: Unreleased Structures]]
		+	[[Category: Qi, X]]

OCA at 14:18, 10 December 2014

2014-12-10T14:18:29Z

←Older revision		Revision as of 14:18, 10 December 2014
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4x30 is ON HOLD	+	The entry 4x30 is ON HOLD until Paper Publication

	Authors: Qi, X.		Authors: Qi, X.

	Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution		Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution

OCA: Protected "4x30" [edit=sysop:move=sysop]

2014-12-03T08:47:38Z

Protected "4x30" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:47, 3 December 2014

OCA: New page: '''Unreleased structure''' The entry 4x30 is ON HOLD Authors: Qi, X. Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolut...

2014-12-03T08:47:37Z

New page: '''Unreleased structure''' The entry 4x30 is ON HOLD Authors: Qi, X. Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolut...

New page

'''Unreleased structure'''

The entry 4x30 is ON HOLD

Authors: Qi, X.

Description: Crystal structure of human Thyroxine-binding globulin complexed with thyroine at 1.55 Angstrom resolution