4xky - Revision history

OCA at 17:41, 26 April 2023

2023-04-26T17:41:37Z

←Older revision		Revision as of 17:41, 26 April 2023
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	<StructureSection load='4xky' size='340' side='right'caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4xky' size='340' side='right'caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xky]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Bactn Bactn~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4XKY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XKY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:~~SODIUM+ION~~'>NA</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat">~~<scene name='pdbligand=~~MHO~~:~~S-OXYMETHIONINE~~'>~~MHO~~</scene>~~</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [https://pdbe.org/4xky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [https://www.ebi.ac.uk/pdbsum/4xky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xky ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BT_2814 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226186 BACTN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [~~http~~://pdbe.org/4xky PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4xky PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4xky ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q8A3Z0_BACTN Q8A3Z0_BACTN]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Bactn~~]]	+	[[Category: Bacteroides thetaiotaomicron VPI-5482]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Arnette~~, A K~~]]	+	[[Category: Arnette AK]]
-	[[Category: Chruszcz, M]]	+	[[Category: Chruszcz M]]
-	[[Category: Klapper~~, V G~~]]	+	[[Category: Klapper VG]]
-	[[Category: Mank~~, N J]]~~	+	[[Category: Mank NJ]]
-	~~[[Category: Aldolase]]~~	+
-	~~[[Category: Diaminopimelate]]~~	+
-	~~[[Category: Dihydrodipicolinate synthase]]~~	+
-	~~[[Category: Lyase]]~~	+
-	~~[[Category: Lysine]]~~	+
-	~~[[Category: Tetramer~~]]	+

OCA at 07:02, 29 May 2019

2019-05-29T07:02:02Z

←Older revision		Revision as of 07:02, 29 May 2019
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	==Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution==		==Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution==
-	<StructureSection load='4xky' size='340' side='right' caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>	+	<StructureSection load='4xky' size='340' side='right'caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xky]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XKY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xky]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XKY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BT_2814 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226186 BACTN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://pdbe.org/4xky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xky ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://pdbe.org/4xky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xky ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 4xky" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 4xky" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Dihydrodipicolinate synthase\|Dihydrodipicolinate synthase]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Bactn]]
		+	[[Category: Large Structures]]
	[[Category: Arnette, A K]]		[[Category: Arnette, A K]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]

OCA at 18:42, 1 February 2017

2017-02-01T18:42:52Z

←Older revision		Revision as of 18:42, 1 February 2017
Line 1:		Line 1:
		+
	==Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution==		==Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution==
	<StructureSection load='4xky' size='340' side='right' caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>		<StructureSection load='4xky' size='340' side='right' caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>
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	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>		<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://pdbe.org/4xky PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xky ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4xky" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 06:52, 22 April 2015

2015-04-22T06:52:06Z

←Older revision		Revision as of 06:52, 22 April 2015
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Dihydrodipicolinate synthase (DapA) catalyzes the first committed step of the diaminopimelate biosynthetic pathway of lysine. It has been shown to be an essential enzyme in many bacteria and has been the subject of research to generate novel antibiotics. However, this pathway is present in both pathogenic and commensal bacteria, and antibiotics targeting DapA may interfere with normal gut colonization. Bacteroides thetaiotaomicron is a Gram-negative commensal bacterium that makes up a large proportion of the normal microbiota of the human gut. The structure of DapA from B. thetaiotaomicron (BtDapA) has been determined. This structure will help to guide the generation of selectively active antibiotic compounds targeting DapA.
		+
		+	Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution.,Mank N, Arnette A, Klapper V, Offermann L, Chruszcz M Acta Crystallogr F Struct Biol Commun. 2015 Apr;71(Pt 4):449-54. doi:, 10.1107/S2053230X15004628. Epub 2015 Mar 20. PMID:25849508<ref>PMID:25849508</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 13:22, 1 April 2015

2015-04-01T13:22:02Z

←Older revision		Revision as of 13:22, 1 April 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Structure of dihydrodipicolinate synthase from the commensal bacterium Bacteroides thetaiotaomicron at 2.1 A resolution==
-		+	<StructureSection load='4xky' size='340' side='right' caption='[[4xky]], [[Resolution\|resolution]] 2.10Å' scene=''>
-	~~The entry~~ 4xky is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[4xky]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XKY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XKY FirstGlance]. <br>
-	~~Authors~~: ~~Mank, N~~.J.~~, Arnette, A~~.K.~~, Klapper, V~~.G.~~, Chruszcz, M~~.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-		+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MHO:S-OXYMETHIONINE'>MHO</scene></td></tr>
-	~~Description:~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xky OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xky RCSB], [http://www.ebi.ac.uk/pdbsum/4xky PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Klapper, V.G~~]]	+	__TOC__
-	[[~~Category~~: ~~Mank~~, N.J]]	+	</StructureSection>
-	[[Category: Arnette, A.K]]	+	[[Category: Arnette, A K]]
	[[Category: Chruszcz, M]]		[[Category: Chruszcz, M]]
		+	[[Category: Klapper, V G]]
		+	[[Category: Mank, N J]]
		+	[[Category: Aldolase]]
		+	[[Category: Diaminopimelate]]
		+	[[Category: Dihydrodipicolinate synthase]]
		+	[[Category: Lyase]]
		+	[[Category: Lysine]]
		+	[[Category: Tetramer]]

OCA: Protected "4xky" [edit=sysop:move=sysop]

2015-01-21T15:58:23Z

Protected "4xky" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:58, 21 January 2015

OCA: New page: '''Unreleased structure''' The entry 4xky is ON HOLD Authors: Mank, N.J., Arnette, A.K., Klapper, V.G., Chruszcz, M. Description: Category: Unreleased Structures [[Category: Klapp...

2015-01-21T15:58:22Z

New page: '''Unreleased structure''' The entry 4xky is ON HOLD Authors: Mank, N.J., Arnette, A.K., Klapper, V.G., Chruszcz, M. Description: Category: Unreleased Structures [[Category: Klapp...

New page

'''Unreleased structure'''

The entry 4xky is ON HOLD

Authors: Mank, N.J., Arnette, A.K., Klapper, V.G., Chruszcz, M.

Description:
[[Category: Unreleased Structures]]
[[Category: Klapper, V.G]]
[[Category: Mank, N.J]]
[[Category: Arnette, A.K]]
[[Category: Chruszcz, M]]