4xm4 - Revision history

OCA at 11:29, 9 May 2024

2024-05-09T11:29:56Z

←Older revision		Revision as of 11:29, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [https://pdbe.org/4xm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xm4 ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.95Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [https://pdbe.org/4xm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xm4 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 17:42, 26 April 2023

2023-04-26T17:42:39Z

←Older revision		Revision as of 17:42, 26 April 2023
Line 3:		Line 3:
	<StructureSection load='4xm4' size='340' side='right'caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='4xm4' size='340' side='right'caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Chaetomium_thermophilum Chaetomium thermophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [~~http~~://pdbe.org/4xm4 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/4xm4 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=4xm4 ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [https://pdbe.org/4xm4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [https://www.ebi.ac.uk/pdbsum/4xm4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4xm4 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G0SET4_CHATD G0SET4_CHATD]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Chaetomium thermophilum]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Aibara, S]]	+	[[Category: Aibara S]]
-	[[Category: Stewart, M]]	+	[[Category: Stewart M]]
-	[[Category: Valkov, M]]	+	[[Category: Valkov M]]
-	~~[[Category: Mrna export]]~~	+
-	~~[[Category: Nuclear transport]]~~	+
-	~~[[Category: Transport protein~~]]	+

OCA at 06:58, 10 July 2019

2019-07-10T06:58:17Z

←Older revision		Revision as of 06:58, 10 July 2019
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	==Structure of Chaetomium Mex67:Mtr2 subunits==		==Structure of Chaetomium Mex67:Mtr2 subunits==
-	<StructureSection load='4xm4' size='340' side='right' caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>	+	<StructureSection load='4xm4' size='340' side='right'caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>
Line 19:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
	[[Category: Stewart, M]]		[[Category: Stewart, M]]

OCA at 13:26, 19 April 2017

2017-04-19T13:26:25Z

←Older revision		Revision as of 13:26, 19 April 2017
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		+
	==Structure of Chaetomium Mex67:Mtr2 subunits==		==Structure of Chaetomium Mex67:Mtr2 subunits==
	<StructureSection load='4xm4' size='340' side='right' caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='4xm4' size='340' side='right' caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>		<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xm4 PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [http://pdbe.org/4xm4 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xm4 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4xm4 ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 4xm4" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 13:27, 15 July 2015

2015-07-15T13:27:57Z

←Older revision		Revision as of 13:27, 15 July 2015
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-	'''~~Unreleased~~ structure'''	+	==Structure of Chaetomium Mex67:Mtr2 subunits==
		+	<StructureSection load='4xm4' size='340' side='right' caption='[[4xm4]], [[Resolution\|resolution]] 2.95Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[4xm4]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4XM4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4XM4 FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4xm4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4xm4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4xm4 RCSB], [http://www.ebi.ac.uk/pdbsum/4xm4 PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Members of the Mex67-Mtr2/NXF-NXT1 family are the principal mediators of the nuclear export of mRNA. Mex67/NXF1 has a modular structure based on four domains (RRM, LRR, NTF2-like and UBA) that are thought to be present across species, although the level of sequence conservation between organisms, especially in lower eukaryotes, is low. Here, the crystal structures of these domains from the thermophilic fungus Chaetomium thermophilum are presented together with small-angle X-ray scattering (SAXS) and in vitro RNA-binding data that indicate that, not withstanding the limited sequence conservation between different NXF family members, the molecules retain similar structural and RNA-binding properties. Moreover, the resolution of crystal structures obtained with the C. thermophilum domains was often higher than that obtained previously and, when combined with solution and biochemical studies, provided insight into the structural organization, self-association and RNA-binding properties of Mex67-Mtr2 that facilitate mRNA nuclear export.

-	~~The entry 4xm4 is ON HOLD until Paper Publication~~	+	Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.,Aibara S, Valkov E, Lamers MH, Dimitrova L, Hurt E, Stewart M Acta Crystallogr F Struct Biol Commun. 2015 Jul;71(Pt 7):876-88. doi:, 10.1107/S2053230X15008766. Epub 2015 Jun 27. PMID:26144233<ref>PMID:26144233</ref>

-	~~Authors: Aibara~~, S.~~, Valkov, M., Stewart, M~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Structure of Chaetomium Mex67:Mtr2 subunits~~	+	== References ==
-	~~[[Category: Unreleased Structures]]~~	+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Aibara, S]]		[[Category: Aibara, S]]
		+	[[Category: Stewart, M]]
	[[Category: Valkov, M]]		[[Category: Valkov, M]]
-	[[Category: ~~Stewart, M~~]]	+	[[Category: Mrna export]]
		+	[[Category: Nuclear transport]]
		+	[[Category: Transport protein]]

OCA at 15:32, 28 January 2015

2015-01-28T15:32:51Z

←Older revision		Revision as of 15:32, 28 January 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 4xm4 is ON HOLD	+	The entry 4xm4 is ON HOLD until Paper Publication

	Authors: Aibara, S., Valkov, M., Stewart, M.		Authors: Aibara, S., Valkov, M., Stewart, M.

OCA: Protected "4xm4" [edit=sysop:move=sysop]

2015-01-21T16:00:59Z

Protected "4xm4" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:00, 21 January 2015

OCA: New page: '''Unreleased structure''' The entry 4xm4 is ON HOLD Authors: Aibara, S., Valkov, M., Stewart, M. Description: Structure of Chaetomium Mex67:Mtr2 subunits [[Category: Unreleased Struct...

2015-01-21T16:00:57Z

New page: '''Unreleased structure''' The entry 4xm4 is ON HOLD Authors: Aibara, S., Valkov, M., Stewart, M. Description: Structure of Chaetomium Mex67:Mtr2 subunits [[Category: Unreleased Struct...

New page

'''Unreleased structure'''

The entry 4xm4 is ON HOLD

Authors: Aibara, S., Valkov, M., Stewart, M.

Description: Structure of Chaetomium Mex67:Mtr2 subunits
[[Category: Unreleased Structures]]
[[Category: Aibara, S]]
[[Category: Valkov, M]]
[[Category: Stewart, M]]