5aed - Revision history

OCA at 11:39, 9 May 2024

2024-05-09T11:39:59Z

←Older revision		Revision as of 11:39, 9 May 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AED FirstGlance]. <br>		<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AED FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.91Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [https://pdbe.org/5aed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [https://www.ebi.ac.uk/pdbsum/5aed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aed ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [https://pdbe.org/5aed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [https://www.ebi.ac.uk/pdbsum/5aed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aed ProSAT]</span></td></tr>
	</table>		</table>

OCA at 04:53, 25 May 2023

2023-05-25T04:53:40Z

←Older revision		Revision as of 04:53, 25 May 2023
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	<StructureSection load='5aed' size='340' side='right'caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='5aed' size='340' side='right'caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5AED FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AED FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aee\|5aee]], [[5aeg\|5aeg]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [https://pdbe.org/5aed PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [https://www.ebi.ac.uk/pdbsum/5aed PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aed ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [~~http~~://pdbe.org/5aed PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5aed PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5aed ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~YIHQ_ECOLI YIHQ_ECOLI~~]~~] Exhibits~~ hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed.<ref>PMID:15294295</ref>	+	[https://www.uniprot.org/uniprot/SQASE_ECOLI SQASE_ECOLI] Catalyzes the hydrolysis of sulfoquinovosyl diacylglycerides (SQDG) to sulfoquinovose (SQ), which is then degraded by E.coli through the SQ Embden-Meyerhof-Parnas (SQ-EMP) sulfoglycolysis pathway as a source of carbon and sulfur. Therefore, is likely involved in the utilization of the sulfoquinovose headgroup found in ubiquitous plant sulfolipids. Is also able to hydrolyze simple sulfoquinovosides such as 1-sulfoquinovosylglycerol (SQGro). Is a retaining glycoside hydrolase, since it forms the alpha anomer of SQ (PubMed:26878550). Also exhibits some alpha-glucosidase activity against alpha-glucosyl fluoride in vitro, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed (PubMed:15294295).<ref>PMID:15294295</ref> <ref>PMID:26878550</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Davies~~, G J~~]]	+	[[Category: Davies GJ]]
-	[[Category: Goddard-Borger~~, E D~~]]	+	[[Category: Goddard-Borger ED]]
-	[[Category: Jin, Y]]	+	[[Category: Jin Y]]
-	[[Category: Speciale, G]]	+	[[Category: Speciale G]]
-	[[Category: Williams~~, S J]]~~	+	[[Category: Williams SJ]]
-	~~[[Category: Alpha-sulfoquinovosidase]]~~	+
-	~~[[Category: Gh31]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 12:57, 10 May 2019

2019-05-10T12:57:02Z

←Older revision		Revision as of 12:57, 10 May 2019
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-	==A bacterial protein structure in glycoside hydrolase family 31.==	+	==A bacterial protein structure in glycoside hydrolase family 31==
-	<StructureSection load='5aed' size='340' side='right' caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>	+	<StructureSection load='5aed' size='340' side='right'caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AED FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AED FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aee\|5aee]], [[5aeg\|5aeg]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aee\|5aee]], [[5aeg\|5aeg]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [http://pdbe.org/5aed PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [http://www.ebi.ac.uk/pdbsum/5aed PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [http://pdbe.org/5aed PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [http://www.ebi.ac.uk/pdbsum/5aed PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aed ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5aed" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5aed" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Alpha-glucosidase 3D structures\|Alpha-glucosidase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Davies, G J]]		[[Category: Davies, G J]]
	[[Category: Goddard-Borger, E D]]		[[Category: Goddard-Borger, E D]]

OCA at 06:52, 2 March 2016

2016-03-02T06:52:58Z

←Older revision		Revision as of 06:52, 2 March 2016
Line 1:		Line 1:
		+
	==A bacterial protein structure in glycoside hydrolase family 31.==		==A bacterial protein structure in glycoside hydrolase family 31.==
	<StructureSection load='5aed' size='340' side='right' caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>		<StructureSection load='5aed' size='340' side='right' caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>
Line 9:		Line 10:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/YIHQ_ECOLI YIHQ_ECOLI]] Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed.<ref>PMID:15294295</ref>		[[http://www.uniprot.org/uniprot/YIHQ_ECOLI YIHQ_ECOLI]] Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed.<ref>PMID:15294295</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Sulfoquinovose is produced by photosynthetic organisms at a rate of 1010 tons per annum and is degraded by bacteria as a source of carbon and sulfur. We have identified Escherichia coli YihQ as the first dedicated sulfoquinovosidase and the gateway enzyme to sulfoglycolytic pathways. Structural and mutagenesis studies unveiled the sequence signatures for binding the distinguishing sulfonate residue and revealed that sulfoquinovoside degradation is widespread across the tree of life.
		+
		+	YihQ is a sulfoquinovosidase that cleaves sulfoquinovosyl diacylglyceride sulfolipids.,Speciale G, Jin Y, Davies GJ, Williams SJ, Goddard-Borger ED Nat Chem Biol. 2016 Feb 15. doi: 10.1038/nchembio.2023. PMID:26878550<ref>PMID:26878550</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5aed" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 17:24, 10 February 2016

2016-02-10T17:24:02Z

←Older revision		Revision as of 17:24, 10 February 2016
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==A bacterial protein structure in glycoside hydrolase family 31.==
-		+	<StructureSection load='5aed' size='340' side='right' caption='[[5aed]], [[Resolution\|resolution]] 1.91Å' scene=''>
-	~~The entry~~ 5aed is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5aed]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AED OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AED FirstGlance]. <br>
-	~~Authors~~: ~~Jin, Y~~.~~, Speciale, G~~.~~, Davies, G~~.J.~~, Williams, S~~.J.~~, Goddard~~-~~Borger, E~~.D.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aee\|5aee]], [[5aeg\|5aeg]]</td></tr>
-	~~Description~~: ~~A bacterial protein structure in glycoside hydrolase family 31.~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aed FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aed OCA], [http://pdbe.org/5aed PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aed RCSB], [http://www.ebi.ac.uk/pdbsum/5aed PDBsum]</span></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	</table>
-	[[~~Category~~: ~~Goddard~~-~~Borger~~, E.D]]	+	== Function ==
-	[[~~Category~~: ~~Williams, S~~.J]]	+	[[http://www.uniprot.org/uniprot/YIHQ_ECOLI YIHQ_ECOLI]] Exhibits hydrolysis activity against alpha-glucosyl fluoride, although natural substrates, such as alpha-glucobioses are scarcely hydrolyzed.<ref>PMID:15294295</ref>
-	[[Category: ~~Speciale~~, G]]	+	== References ==
-	[[Category: ~~Davies~~, ~~G.J~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Davies, G J]]
		+	[[Category: Goddard-Borger, E D]]
	[[Category: Jin, Y]]		[[Category: Jin, Y]]
		+	[[Category: Speciale, G]]
		+	[[Category: Williams, S J]]
		+	[[Category: Alpha-sulfoquinovosidase]]
		+	[[Category: Gh31]]
		+	[[Category: Hydrolase]]

OCA at 09:46, 16 December 2015

2015-12-16T09:46:30Z

←Older revision		Revision as of 09:46, 16 December 2015
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Goddard-Borger, E.D]]		[[Category: Goddard-Borger, E.D]]
-	[[Category: Davies, G.J]]
	[[Category: Williams, S.J]]		[[Category: Williams, S.J]]
	[[Category: Speciale, G]]		[[Category: Speciale, G]]
		+	[[Category: Davies, G.J]]
	[[Category: Jin, Y]]		[[Category: Jin, Y]]

OCA at 11:07, 30 September 2015

2015-09-30T11:07:01Z

←Older revision		Revision as of 11:07, 30 September 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5aed is ON HOLD	+	The entry 5aed is ON HOLD until Paper Publication

	Authors: Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.		Authors: Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.

-	Description: A bacterial ~~sulfoquinovosidase~~ in glycoside hydrolase family 31.	+	Description: A bacterial protein structure in glycoside hydrolase family 31.
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Goddard-Borger, E.D]]		[[Category: Goddard-Borger, E.D]]

OCA: Protected "5aed" [edit=sysop:move=sysop]

2015-09-09T08:21:45Z

Protected "5aed" [edit=sysop:move=sysop]

←Older revision

Revision as of 08:21, 9 September 2015

OCA: New page: '''Unreleased structure''' The entry 5aed is ON HOLD Authors: Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D. Description: A bacterial sulfoquinovosidase in g...

2015-09-09T08:21:43Z

New page: '''Unreleased structure''' The entry 5aed is ON HOLD Authors: Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D. Description: A bacterial sulfoquinovosidase in g...

New page

'''Unreleased structure'''

The entry 5aed is ON HOLD

Authors: Jin, Y., Speciale, G., Davies, G.J., Williams, S.J., Goddard-Borger, E.D.

Description: A bacterial sulfoquinovosidase in glycoside hydrolase family 31.
[[Category: Unreleased Structures]]
[[Category: Goddard-Borger, E.D]]
[[Category: Davies, G.J]]
[[Category: Williams, S.J]]
[[Category: Speciale, G]]
[[Category: Jin, Y]]