5ajw - Revision history

OCA at 11:41, 9 May 2024

2024-05-09T11:41:28Z

←Older revision		Revision as of 11:41, 9 May 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJW FirstGlance]. <br>		<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [https://pdbe.org/5ajw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [https://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [https://pdbe.org/5ajw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [https://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr>
	</table>		</table>

OCA at 05:04, 25 May 2023

2023-05-25T05:04:39Z

←Older revision		Revision as of 05:04, 25 May 2023
Line 3:		Line 3:
	<StructureSection load='5ajw' size='340' side='right'caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='5ajw' size='340' side='right'caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5AJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AJW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [https://pdbe.org/5ajw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [https://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [~~http~~://pdbe.org/5ajw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN]] Synthesis and degradation of fructose 2,6-bisphosphate.	+	[https://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN] Synthesis and degradation of fructose 2,6-bisphosphate.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Boyd, S]]	+	[[Category: Boyd S]]
-	[[Category: Brookfield~~, J L~~]]	+	[[Category: Brookfield JL]]
-	[[Category: Critchlow~~, S E~~]]	+	[[Category: Critchlow SE]]
-	[[Category: Cumming~~, I A~~]]	+	[[Category: Cumming IA]]
-	[[Category: Curtis~~, N J~~]]	+	[[Category: Curtis NJ]]
-	[[Category: Debreczeni~~, J E~~]]	+	[[Category: Debreczeni JE]]
-	[[Category: Degorce~~, S L~~]]	+	[[Category: Degorce SL]]
-	[[Category: Donald, C]]	+	[[Category: Donald C]]
-	[[Category: Evans~~, N J~~]]	+	[[Category: Evans NJ]]
-	[[Category: Groombridge, S]]	+	[[Category: Groombridge S]]
-	[[Category: Hopcroft, P]]	+	[[Category: Hopcroft P]]
-	[[Category: Jones~~, N P~~]]	+	[[Category: Jones NP]]
-	[[Category: Kettle~~, J G~~]]	+	[[Category: Kettle JG]]
-	[[Category: Lamont, S]]	+	[[Category: Lamont S]]
-	[[Category: Lewis~~, H J~~]]	+	[[Category: Lewis HJ]]
-	[[Category: MacFaull, P]]	+	[[Category: MacFaull P]]
-	[[Category: McLoughlin~~, S B~~]]	+	[[Category: McLoughlin SB]]
-	[[Category: Rigoreau~~, L J.M~~]]	+	[[Category: Rigoreau LJM]]
-	[[Category: Smith~~, J M~~]]	+	[[Category: Smith JM]]
-	[[Category: St-Gallay, S]]	+	[[Category: St-Gallay S]]
-	[[Category: Stock~~, J K~~]]	+	[[Category: Stock JK]]
-	[[Category: Wheatley~~, E R~~]]	+	[[Category: Wheatley ER]]
-	[[Category: Wingfield, J]]	+	[[Category: Wingfield J]]
-	[[Category: Winter, J]]	+	[[Category: Winter J]]
-	~~[[Category: Transferase~~]]	+

OCA at 07:53, 3 July 2019

2019-07-03T07:53:45Z

←Older revision		Revision as of 07:53, 3 July 2019
Line 1:		Line 1:

	==Human PFKFB3 in complex with an indole inhibitor 2==		==Human PFKFB3 in complex with an indole inhibitor 2==
-	<StructureSection load='5ajw' size='340' side='right' caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='5ajw' size='340' side='right'caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]</td></tr>
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Boyd, S]]		[[Category: Boyd, S]]
	[[Category: Brookfield, J L]]		[[Category: Brookfield, J L]]

OCA at 10:00, 10 March 2017

2017-03-10T10:00:59Z

←Older revision		Revision as of 10:00, 10 March 2017
Line 1:		Line 1:
		+
	==Human PFKFB3 in complex with an indole inhibitor 2==		==Human PFKFB3 in complex with an indole inhibitor 2==
	<StructureSection load='5ajw' size='340' side='right' caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='5ajw' size='340' side='right' caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>
Line 5:		Line 6:
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [http://www.ebi.ac.uk/pdbsum/5ajw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [http://pdbe.org/5ajw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [http://www.ebi.ac.uk/pdbsum/5ajw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ajw ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 17:		Line 18:
	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>		From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
	</div>		</div>
		+	<div class="pdbe-citations 5ajw" style="background-color:#fffaf0;"></div>
	== References ==		== References ==
	<references/>		<references/>

OCA at 12:47, 22 April 2015

2015-04-22T12:47:16Z

←Older revision		Revision as of 12:47, 22 April 2015
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Human PFKFB3 in complex with an indole inhibitor 2==
		+	<StructureSection load='5ajw' size='340' side='right' caption='[[5ajw]], [[Resolution\|resolution]] 2.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5ajw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AJW FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=F6P:FRUCTOSE-6-PHOSPHATE'>F6P</scene>, <scene name='pdbligand=PHS:PHOSPHONIC+ACID'>PHS</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=S6L:2-AMINO-N-[4-(2-AMINO-1-BENZYL-3-CYANO-INDOL-5-YL)OXYPHENYL]ACETAMIDE'>S6L</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5ajv\|5ajv]], [[5ajx\|5ajx]], [[5ajy\|5ajy]], [[5ajz\|5ajz]], [[5ak0\|5ak0]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ajw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ajw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5ajw RCSB], [http://www.ebi.ac.uk/pdbsum/5ajw PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/F263_HUMAN F263_HUMAN]] Synthesis and degradation of fructose 2,6-bisphosphate.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A weak screening hit with suboptimal physicochemical properties was optimized against PFKFB3 kinase using critical structure-guided insights. The resulting compounds demonstrated high selectivity over related PFKFB isoforms and modulation of the target in a cellular context. A selected example demonstrated exposure in animals following oral dosing. Examples from this series may serve as useful probes to understand the emerging biology of this metabolic target.

-	~~The entry 5ajw is ON HOLD~~	+	Structure-Based Design of Potent and Selective Inhibitors of the Metabolic Kinase PFKFB3.,Boyd S, Brookfield JL, Critchlow SE, Cumming IA, Curtis NJ, Debreczeni J, Degorce SL, Donald C, Evans NJ, Groombridge S, Hopcroft P, Jones NP, Kettle JG, Lamont S, Lewis HJ, MacFaull P, McLoughlin SB, Rigoreau LJ, Smith JM, St-Gallay S, Stock JK, Turnbull AP, Wheatley ER, Winter J, Wingfield J J Med Chem. 2015 Apr 13. PMID:25849762<ref>PMID:25849762</ref>

-	~~Authors: Boyd~~, S.~~, Brookfield, J.L., Critchlow,~~ S.E., Cumming, I.A., Curtis, N.J., Debreczeni, J.E., Degorce, S.L., Donald, C., Evans, N.J., Groombridge, S., Hopcroft, P., Jones, N.P., Kettle, J.G., Lamont, S., Lewis, H.J., MacFaull, P., McLoughlin, S.B., Rigoreau, L.J.M., Smith, J.M., St-Gallay, S., Stock, J.K., Wheatley, E.R., Winter, J., Wingfield, J.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Human PFKFB3 in complex with an indole inhibitor 2~~	+	== References ==
-	[[Category: ~~Unreleased Structures~~]]	+	<references/>
-	[[Category: ~~Stock~~, J.K]]	+	__TOC__
-	[[Category: ~~Mcloughlin~~, S.B]]	+	</StructureSection>
-	[[Category: ~~St-Gallay~~, S]]	+	[[Category: Boyd, S]]
-	[[Category: ~~Cumming~~, ~~I.A~~]]	+	[[Category: Brookfield, J L]]
-	[[Category: ~~Wheatley~~, E.R]]	+	[[Category: Critchlow, S E]]
-	[[Category: ~~Hopcroft~~, P]]	+	[[Category: Cumming, I A]]
		+	[[Category: Curtis, N J]]
		+	[[Category: Debreczeni, J E]]
		+	[[Category: Degorce, S L]]
	[[Category: Donald, C]]		[[Category: Donald, C]]
-	[[Category: ~~Debreczeni, J.E]]~~	+	[[Category: Evans, N J]]
-	~~[[Category: Curtis~~, N.J]]	+
-	~~[[Category: Kettle, J.G]]~~	+
-	~~[[Category: Jones, N.P]]~~	+
-	~~[[Category: Macfaull, P]]~~	+
-	~~[[Category: Brookfield, J.L]]~~	+
-	~~[[Category: Rigoreau, L.J.M]]~~	+
-	~~[[Category: Lewis, H.J]]~~	+
-	~~[[Category: Degorce, S.L~~]]	+
	[[Category: Groombridge, S]]		[[Category: Groombridge, S]]
-	[[Category: ~~Smith~~, J.M]]	+	[[Category: Hopcroft, P]]
-	[[Category: ~~Evans~~, N.J]]	+	[[Category: Jones, N P]]
		+	[[Category: Kettle, J G]]
		+	[[Category: Lamont, S]]
		+	[[Category: Lewis, H J]]
		+	[[Category: MacFaull, P]]
		+	[[Category: McLoughlin, S B]]
		+	[[Category: Rigoreau, L J.M]]
		+	[[Category: Smith, J M]]
		+	[[Category: St-Gallay, S]]
		+	[[Category: Stock, J K]]
		+	[[Category: Wheatley, E R]]
	[[Category: Wingfield, J]]		[[Category: Wingfield, J]]
-	[[Category: Critchlow, S.E]]
-	[[Category: Lamont, S]]
-	[[Category: Boyd, S]]
	[[Category: Winter, J]]		[[Category: Winter, J]]
		+	[[Category: Transferase]]

OCA: Protected "5ajw" [edit=sysop:move=sysop]

2015-03-11T11:00:44Z

Protected "5ajw" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:00, 11 March 2015

OCA: New page: '''Unreleased structure''' The entry 5ajw is ON HOLD Authors: Boyd, S., Brookfield, J.L., Critchlow, S.E., Cumming, I.A., Curtis, N.J., Debreczeni, J.E., Degorce, S.L., Donald, C., Evan...

2015-03-11T11:00:43Z

New page: '''Unreleased structure''' The entry 5ajw is ON HOLD Authors: Boyd, S., Brookfield, J.L., Critchlow, S.E., Cumming, I.A., Curtis, N.J., Debreczeni, J.E., Degorce, S.L., Donald, C., Evan...

New page

'''Unreleased structure'''

The entry 5ajw is ON HOLD

Authors: Boyd, S., Brookfield, J.L., Critchlow, S.E., Cumming, I.A., Curtis, N.J., Debreczeni, J.E., Degorce, S.L., Donald, C., Evans, N.J., Groombridge, S., Hopcroft, P., Jones, N.P., Kettle, J.G., Lamont, S., Lewis, H.J., MacFaull, P., McLoughlin, S.B., Rigoreau, L.J.M., Smith, J.M., St-Gallay, S., Stock, J.K., Wheatley, E.R., Winter, J., Wingfield, J.

Description: Human PFKFB3 in complex with an indole inhibitor 2
[[Category: Unreleased Structures]]
[[Category: Stock, J.K]]
[[Category: Mcloughlin, S.B]]
[[Category: St-Gallay, S]]
[[Category: Cumming, I.A]]
[[Category: Wheatley, E.R]]
[[Category: Hopcroft, P]]
[[Category: Donald, C]]
[[Category: Debreczeni, J.E]]
[[Category: Curtis, N.J]]
[[Category: Kettle, J.G]]
[[Category: Jones, N.P]]
[[Category: Macfaull, P]]
[[Category: Brookfield, J.L]]
[[Category: Rigoreau, L.J.M]]
[[Category: Lewis, H.J]]
[[Category: Degorce, S.L]]
[[Category: Groombridge, S]]
[[Category: Smith, J.M]]
[[Category: Evans, N.J]]
[[Category: Wingfield, J]]
[[Category: Critchlow, S.E]]
[[Category: Lamont, S]]
[[Category: Boyd, S]]
[[Category: Winter, J]]