5aod - Revision history

OCA at 11:14, 10 January 2024

2024-01-10T11:14:06Z

←Older revision		Revision as of 11:14, 10 January 2024
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AOD FirstGlance]. <br>		<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AOD FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [https://pdbe.org/5aod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [https://www.ebi.ac.uk/pdbsum/5aod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [https://pdbe.org/5aod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [https://www.ebi.ac.uk/pdbsum/5aod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 06:20, 31 May 2023

2023-05-31T06:20:05Z

←Older revision		Revision as of 06:20, 31 May 2023
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	<StructureSection load='5aod' size='340' side='right'caption='[[5aod]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='5aod' size='340' side='right'caption='[[5aod]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus~~ pneumoniae~~" (klein 1884) weichselbaum 1886~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5AOD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5AOD FirstGlance]. <br>
-	</td></tr>~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aoe\|5aoe]], [[5aof\|5aof]]</td></tr>~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [https://pdbe.org/5aod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [https://www.ebi.ac.uk/pdbsum/5aod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [~~http~~://pdbe.org/5aod PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5aod PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~TACY_STRP2 TACY_STRP2~~]~~] Sulfhydryl~~-~~activated~~ toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol ~~may be~~ required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation ~~(By similarity)~~.	+	[https://www.uniprot.org/uniprot/TACY_STRR6 TACY_STRR6] A cholesterol-dependent toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol is required for binding to host membranes, membrane insertion and pore formation; cholesterol binding is mediated by a Thr-Leu pair in the C-terminus. Can be reversibly inactivated by oxidation.[UniProtKB:P13128]

	==See Also==		==See Also==
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Pee, K van~~]]	+	[[Category: Streptococcus pneumoniae]]
-	[[Category: Yildiz, O]]	+	[[Category: Yildiz O]]
-	[[Category: ~~Cholesterol dependent cytolysin]]~~	+	[[Category: Van Pee K]]
-	~~[[Category: Pore forming toxin]]~~	+
-	~~[[Category: Toxin~~]]	+

OCA at 07:09, 3 July 2019

2019-07-03T07:09:37Z

←Older revision		Revision as of 07:09, 3 July 2019
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	==Crystal structure of wild type pneumolysin.==		==Crystal structure of wild type pneumolysin.==
-	<StructureSection load='5aod' size='340' side='right' caption='[[5aod]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='5aod' size='340' side='right'caption='[[5aod]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AOD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"diplococcus_pneumoniae"_(klein_1884)_weichselbaum_1886 "diplococcus pneumoniae" (klein 1884) weichselbaum 1886]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AOD FirstGlance]. <br>
	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aoe\|5aoe]], [[5aof\|5aof]]</td></tr>		</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aoe\|5aoe]], [[5aof\|5aof]]</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [http://pdbe.org/5aod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [http://www.ebi.ac.uk/pdbsum/5aod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [http://pdbe.org/5aod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [http://www.ebi.ac.uk/pdbsum/5aod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>
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	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/TACY_STRP2 TACY_STRP2]] Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).		[[http://www.uniprot.org/uniprot/TACY_STRP2 TACY_STRP2]] Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
		+
		+	==See Also==
		+	*[[Cytolysin 3D structures\|Cytolysin 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Pee, K van]]		[[Category: Pee, K van]]
	[[Category: Yildiz, O]]		[[Category: Yildiz, O]]

OCA at 21:19, 5 October 2016

2016-10-05T21:19:47Z

←Older revision		Revision as of 21:19, 5 October 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5aod is ~~ON HOLD~~	+	==Crystal structure of wild type pneumolysin.==
-		+	<StructureSection load='5aod' size='340' side='right' caption='[[5aod]], [[Resolution\|resolution]] 2.40Å' scene=''>
-	~~Authors~~: ~~van Pee~~, K., ~~Yildiz~~, O.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5aod]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5AOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5AOD FirstGlance]. <br>
-	~~Description~~: ~~Crystal structure~~ of ~~wild type pneumolysin~~.	+	</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5aoe\|5aoe]], [[5aof\|5aof]]</td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5aod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5aod OCA], [http://pdbe.org/5aod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5aod RCSB], [http://www.ebi.ac.uk/pdbsum/5aod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5aod ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TACY_STRP2 TACY_STRP2]] Sulfhydryl-activated toxin that causes cytolysis by forming pores in cholesterol containing host membranes. After binding to target membranes, the protein undergoes a major conformation change, leading to its insertion in the host membrane and formation of an oligomeric pore complex. Cholesterol may be required for binding to host membranes, membrane insertion and pore formation. Can be reversibly inactivated by oxidation (By similarity).
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Pee, K van]]
	[[Category: Yildiz, O]]		[[Category: Yildiz, O]]
-	[[Category: ~~Van Pee, K~~]]	+	[[Category: Cholesterol dependent cytolysin]]
		+	[[Category: Pore forming toxin]]
		+	[[Category: Toxin]]

OCA: Protected "5aod" [edit=sysop:move=sysop]

2015-09-30T11:16:15Z

Protected "5aod" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:16, 30 September 2015

OCA: New page: '''Unreleased structure''' The entry 5aod is ON HOLD Authors: van Pee, K., Yildiz, O. Description: Crystal structure of wild type pneumolysin. Category: Unreleased Structures [[Cat...

2015-09-30T11:16:14Z

New page: '''Unreleased structure''' The entry 5aod is ON HOLD Authors: van Pee, K., Yildiz, O. Description: Crystal structure of wild type pneumolysin. Category: Unreleased Structures [[Cat...

New page

'''Unreleased structure'''

The entry 5aod is ON HOLD

Authors: van Pee, K., Yildiz, O.

Description: Crystal structure of wild type pneumolysin.
[[Category: Unreleased Structures]]
[[Category: Yildiz, O]]
[[Category: Van Pee, K]]