5b25 - Revision history

OCA at 15:56, 8 November 2023

2023-11-08T15:56:22Z

←Older revision		Revision as of 15:56, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B25 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B25 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.9Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [https://pdbe.org/5b25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [https://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [https://pdbe.org/5b25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [https://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:36, 31 May 2023

2023-05-31T06:36:11Z

←Older revision		Revision as of 06:36, 31 May 2023
Line 3:		Line 3:
	<StructureSection load='5b25' size='340' side='right'caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5b25' size='340' side='right'caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5B25 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B25 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PDE1B, PDE1B1, PDES1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [https://pdbe.org/5b25 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [https://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr>
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [~~http~~://pdbe.org/5b25 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PDE1B_HUMAN PDE1B_HUMAN]] Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.	+	[https://www.uniprot.org/uniprot/PDE1B_HUMAN PDE1B_HUMAN] Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 27:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~3',5'-cyclic-nucleotide phosphodiesterase]]~~	+	[[Category: Homo sapiens]]
-	~~[[Category: Human~~]]	+
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Ida, K]]	+	[[Category: Ida K]]
-	[[Category: Lane, W]]	+	[[Category: Lane W]]
-	[[Category: Snell, G]]	+	[[Category: Snell G]]
-	[[Category: Sogabe, S]]	+	[[Category: Sogabe S]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Hydrolase-hydrolase inhibitor complex]]~~	+
-	~~[[Category: Inhibitor~~]]	+

OCA at 08:45, 11 March 2020

2020-03-11T08:45:05Z

←Older revision		Revision as of 08:45, 11 March 2020
Line 1:		Line 1:

	==Crystal structure of human PDE1B with inhibitor 3==		==Crystal structure of human PDE1B with inhibitor 3==
-	<StructureSection load='5b25' size='340' side='right' caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>	+	<StructureSection load='5b25' size='340' side='right'caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B25 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B25 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">PDE1B, PDE1B1, PDES1B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [http://pdbe.org/5b25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [http://www.ebi.ac.uk/pdbsum/5b25 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [http://pdbe.org/5b25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [http://www.ebi.ac.uk/pdbsum/5b25 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b25 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 19:		Line 20:
	</div>		</div>
	<div class="pdbe-citations 5b25" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5b25" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Phosphodiesterase 3D structures\|Phosphodiesterase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 24:		Line 28:
	</StructureSection>		</StructureSection>
	[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]		[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Ida, K]]		[[Category: Ida, K]]
	[[Category: Lane, W]]		[[Category: Lane, W]]

OCA at 10:19, 26 February 2016

2016-02-26T10:19:48Z

←Older revision		Revision as of 10:19, 26 February 2016
Line 1:		Line 1:
		+
	==Crystal structure of human PDE1B with inhibitor 3==		==Crystal structure of human PDE1B with inhibitor 3==
	<StructureSection load='5b25' size='340' side='right' caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>		<StructureSection load='5b25' size='340' side='right' caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>

OCA at 15:41, 3 February 2016

2016-02-03T15:41:16Z

←Older revision		Revision as of 15:41, 3 February 2016
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of human PDE1B with inhibitor 3==
		+	<StructureSection load='5b25' size='340' side='right' caption='[[5b25]], [[Resolution\|resolution]] 1.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5b25]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B25 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B25 FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4QJ:(11R,15S)-4-{[4-(6-FLUOROPYRIDIN-2-YL)PHENYL]METHYL}-8-METHYL-5-(PHENYLAMINO)-1,3,4,8,10-PENTAAZATETRACYCLO[7.6.0.02,6.011,15]PENTADECA-2,5,9-TRIEN-7-ONE'>4QJ</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3',5'-cyclic-nucleotide_phosphodiesterase 3',5'-cyclic-nucleotide phosphodiesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.4.17 3.1.4.17] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b25 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b25 OCA], [http://pdbe.org/5b25 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b25 RCSB], [http://www.ebi.ac.uk/pdbsum/5b25 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PDE1B_HUMAN PDE1B_HUMAN]] Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a preference for cGMP as a substrate.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	A diverse set of 3-aminopyrazolo[3,4-d]pyrimidinones was designed and synthesized. The structure-activity relationships of these polycyclic compounds as phosphodiesterase 1 (PDE1) inhibitors were studied along with their physicochemical and pharmacokinetic properties. Systematic optimizations of this novel scaffold culminated in the identification of a clinical candidate, (6aR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9, 9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4-(2H)-one phosphate (ITI-214), which exhibited picomolar inhibitory potency for PDE1, demonstrated excellent selectivity against all other PDE families and showed good efficacy in vivo. Currently, this investigational new drug is in Phase I clinical development and being considered for the treatment of several indications including cognitive deficits associated with schizophrenia and Alzheimer's disease, movement disorders, attention deficit and hyperactivity disorders, and other central nervous system (CNS) and non-CNS disorders.

-	~~The entry 5b25 is ON HOLD until Paper Publication~~	+	Discovery of Potent and Selective Inhibitors of Phosphodiesterase 1 for the Treatment of Cognitive Impairment Associated with Neurodegenerative and Neuropsychiatric Diseases.,Li P, Zheng H, Zhao J, Zhang L, Yao W, Zhu H, Beard JD, Ida K, Lane W, Snell G, Sogabe S, Heyser CJ, Snyder GL, Hendrick JP, Vanover KE, Davis RE, Wennogle LP J Med Chem. 2016 Feb 2. PMID:26789933<ref>PMID:26789933</ref>

-	~~Authors: Ida~~, K.~~, Lane, W., Snell, G., Sogabe,~~ S.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description~~: ~~Crystal structure of human PDE1B with inhibitor~~ 3	+	<div class="pdbe-citations 5b25" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: 3',5'-cyclic-nucleotide phosphodiesterase]]
		+	[[Category: Ida, K]]
		+	[[Category: Lane, W]]
	[[Category: Snell, G]]		[[Category: Snell, G]]
-	[[Category: Lane, W]]
-	[[Category: Ida, K]]
	[[Category: Sogabe, S]]		[[Category: Sogabe, S]]
		+	[[Category: Hydrolase]]
		+	[[Category: Hydrolase-hydrolase inhibitor complex]]
		+	[[Category: Inhibitor]]

OCA at 11:28, 20 January 2016

2016-01-20T11:28:23Z

←Older revision		Revision as of 11:28, 20 January 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5b25 is ON HOLD	+	The entry 5b25 is ON HOLD until Paper Publication

	Authors: Ida, K., Lane, W., Snell, G., Sogabe, S.		Authors: Ida, K., Lane, W., Snell, G., Sogabe, S.

OCA: Protected "5b25" [edit=sysop:move=sysop]

2016-01-13T15:05:21Z

Protected "5b25" [edit=sysop:move=sysop]

←Older revision

Revision as of 15:05, 13 January 2016

OCA: New page: '''Unreleased structure''' The entry 5b25 is ON HOLD Authors: Ida, K., Lane, W., Snell, G., Sogabe, S. Description: Crystal structure of human PDE1B with inhibitor 3 [[Category: Unrele...

2016-01-13T15:05:20Z

New page: '''Unreleased structure''' The entry 5b25 is ON HOLD Authors: Ida, K., Lane, W., Snell, G., Sogabe, S. Description: Crystal structure of human PDE1B with inhibitor 3 [[Category: Unrele...

New page

'''Unreleased structure'''

The entry 5b25 is ON HOLD

Authors: Ida, K., Lane, W., Snell, G., Sogabe, S.

Description: Crystal structure of human PDE1B with inhibitor 3
[[Category: Unreleased Structures]]
[[Category: Snell, G]]
[[Category: Lane, W]]
[[Category: Ida, K]]
[[Category: Sogabe, S]]