5b89 - Revision history

OCA at 16:03, 8 November 2023

2023-11-08T16:03:42Z

←Older revision		Revision as of 16:03, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5b89]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_onnurineus_NA1 Thermococcus onnurineus NA1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B89 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5b89]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_onnurineus_NA1 Thermococcus onnurineus NA1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B89 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [https://pdbe.org/5b89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [https://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [https://pdbe.org/5b89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [https://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:41, 31 May 2023

2023-05-31T06:41:47Z

←Older revision		Revision as of 06:41, 31 May 2023
Line 1:		Line 1:

	==Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution==		==Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution==
-	<StructureSection load='5b89' size='340' side='right' caption='[[5b89]], [[Resolution\|resolution]] 1.50Å' scene=''>	+	<StructureSection load='5b89' size='340' side='right'caption='[[5b89]], [[Resolution\|resolution]] 1.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5b89]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Theon Theon~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B89 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5B89 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5b89]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_onnurineus_NA1 Thermococcus onnurineus NA1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B89 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5B89 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-	~~<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [https://pdbe.org/5b89 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [https://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5b87\|5b87]]</td></tr>~~	+
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TON_0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=523850 THEON])</td></tr>~~	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_desulfurase Cysteine desulfurase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.7 2.8.1.7] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [~~http~~://pdbe.org/5b89 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/B6YT87_THEON B6YT87_THEON]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 20:		Line 18:
	</div>		</div>
	<div class="pdbe-citations 5b89" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5b89" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Cysteine desulfurase 3D structures\|Cysteine desulfurase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cysteine desulfurase~~]]	+	[[Category: Large Structures]]
-	[[Category: ~~Theon~~]]	+	[[Category: Thermococcus onnurineus NA1]]
-	[[Category: Ho, T H]]	+	[[Category: Ho T-H]]
-	[[Category: Kang, L W]]	+	[[Category: Kang L-W]]
-	~~[[Category: L-cysteine sulfur-transferase]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:59, 14 June 2018

2018-06-14T07:59:14Z

←Older revision		Revision as of 07:59, 14 June 2018
Line 11:		Line 11:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [http://pdbe.org/5b89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [http://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [http://pdbe.org/5b89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [http://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Thermococcus onnurineus NA1 is an anaerobic archaeon usually found in a deep-sea hydrothermal vent area, which can use elemental sulfur (S(0)) as a terminal electron acceptor for energy. Sulfur, essential to many biomolecules such as sulfur-containing amino acids and cofactors including iron-sulfur cluster, is usually mobilized from cysteine by the pyridoxal 5'-phosphate- (PLP-) dependent enzyme of cysteine desulfurase (CDS). We determined the crystal structures of CDS from Thermococcus onnurineus NA1 (ToCDS), which include native internal aldimine (NAT), gem-diamine (GD) with alanine, internal aldimine structure with existing alanine (IAA), and internal aldimine with persulfide-bound Cys356 (PSF) structures. The catalytic intermediate structures showed the dihedral angle rotation of Schiff-base linkage relative to the PLP pyridine ring. The ToCDS structures were compared with bacterial CDS structures, which will help us to understand the role and catalytic mechanism of ToCDS in the archaeon Thermococcus onnurineus NA1.
		+
		+	Catalytic Intermediate Crystal Structures of Cysteine Desulfurase from the Archaeon Thermococcus onnurineus NA1.,Ho TH, Huynh KH, Nguyen DQ, Park H, Jung K, Sur B, Ahn YJ, Cha SS, Kang LW Archaea. 2017 Apr 24;2017:5395293. doi: 10.1155/2017/5395293. eCollection 2017. PMID:28536498<ref>PMID:28536498</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5b89" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 09:39, 16 November 2017

2017-11-16T09:39:44Z

←Older revision		Revision as of 09:39, 16 November 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5b89 is ON HOLD until Paper Publication~~	+	==Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution==
-		+	<StructureSection load='5b89' size='340' side='right' caption='[[5b89]], [[Resolution\|resolution]] 1.50Å' scene=''>
-	~~Authors: Ho, T.-H., Kang, L.-W.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5b89]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Theon Theon]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5B89 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5B89 FirstGlance]. <br>
-	~~Description:~~ Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ALA:ALANINE'>ALA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue\|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene></td></tr>
-	[[Category: Ho, T.-H]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5b87\|5b87]]</td></tr>
-	[[Category: Kang, L.-W]]	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TON_0289 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=523850 THEON])</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cysteine_desulfurase Cysteine desulfurase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.8.1.7 2.8.1.7] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5b89 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5b89 OCA], [http://pdbe.org/5b89 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5b89 RCSB], [http://www.ebi.ac.uk/pdbsum/5b89 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5b89 ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Cysteine desulfurase]]
		+	[[Category: Theon]]
		+	[[Category: Ho, T H]]
		+	[[Category: Kang, L W]]
		+	[[Category: L-cysteine sulfur-transferase]]
		+	[[Category: Transferase]]

OCA at 07:42, 26 July 2016

2016-07-26T07:42:34Z

←Older revision		Revision as of 07:42, 26 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5b89 is ON HOLD	+	The entry 5b89 is ON HOLD until Paper Publication

	Authors: Ho, T.-H., Kang, L.-W.		Authors: Ho, T.-H., Kang, L.-W.

OCA at 04:43, 14 July 2016

2016-07-14T04:43:08Z

←Older revision		Revision as of 04:43, 14 July 2016
Line 3:		Line 3:
	The entry 5b89 is ON HOLD		The entry 5b89 is ON HOLD

-	Authors: Ho, ~~Thien~~-~~Hoang~~, Kang, ~~Lin~~-~~Woo~~	+	Authors: Ho, T.-H., Kang, L.-W.

	Description: Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution		Description: Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Ho, ~~Thien~~-~~Hoang,~~ Kang, ~~Lin~~-~~Woo~~]]	+	[[Category: Ho, T.-H]]
		+	[[Category: Kang, L.-W]]

OCA: Protected "5b89" [edit=sysop:move=sysop]

2016-06-23T16:49:09Z

Protected "5b89" [edit=sysop:move=sysop]

←Older revision

Revision as of 16:49, 23 June 2016

OCA: New page: '''Unreleased structure''' The entry 5b89 is ON HOLD Authors: Ho, Thien-Hoang, Kang, Lin-Woo Description: Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 i...

2016-06-23T16:49:08Z

New page: '''Unreleased structure''' The entry 5b89 is ON HOLD Authors: Ho, Thien-Hoang, Kang, Lin-Woo Description: Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 i...

New page

'''Unreleased structure'''

The entry 5b89 is ON HOLD

Authors: Ho, Thien-Hoang, Kang, Lin-Woo

Description: Crystal structure of a Cysteine Desulfurase from Thermococcus onnurineus NA1 in complex with alanine at 1.5 Angstrom resolution
[[Category: Unreleased Structures]]
[[Category: Ho, Thien-Hoang, Kang, Lin-Woo]]