5bo2 - Revision history

OCA at 08:28, 27 September 2023

2023-09-27T08:28:02Z

←Older revision		Revision as of 08:28, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [https://pdbe.org/5bo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [https://pdbe.org/5bo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:01, 7 June 2023

2023-06-07T06:01:31Z

←Older revision		Revision as of 06:01, 7 June 2023
Line 3:		Line 3:
	<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution\|resolution]] 2.00Å' scene=''>		<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Mycta Mycta~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Ra Mycobacterium tuberculosis H37Ra]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qr9\|3qr9]], [[4ij1\|4ij1]], [[5bo3\|5bo3]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [https://pdbe.org/5bo2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [https://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trpD, MRA_2208 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [~~http~~://pdbe.org/5bo2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).	+	[https://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).

	==See Also==		==See Also==
Line 17:		Line 14:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Anthranilate phosphoribosyltransferase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Mycta~~]]	+	[[Category: Mycobacterium tuberculosis H37Ra]]
-	[[Category: Baker~~, E N~~]]	+	[[Category: Baker EN]]
-	[[Category: Evans~~, G L~~]]	+	[[Category: Evans GL]]
-	[[Category: Lott~~, J S]]~~	+	[[Category: Lott JS]]
-	~~[[Category: Structural genomic]]~~	+
-	~~[[Category: Lobenzarit-like analogue]]~~	+
-	~~[[Category: Magnesium binding]]~~	+
-	~~[[Category: Tbsgc]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 08:51, 1 January 2020

2020-01-01T08:51:51Z

←Older revision		Revision as of 08:51, 1 January 2020
Line 1:		Line 1:

	==Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)==		==Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)==
-	<StructureSection load='5bo2' size='340' side='right' caption='[[5bo2]], [[Resolution\|resolution]] 2.00Å' scene=''>	+	<StructureSection load='5bo2' size='340' side='right'caption='[[5bo2]], [[Resolution\|resolution]] 2.00Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycta Mycta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qr9\|3qr9]], [[4ij1\|4ij1]], [[5bo3\|5bo3]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qr9\|3qr9]], [[4ij1\|4ij1]], [[5bo3\|5bo3]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">trpD, MRA_2208 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=419947 MYCTA])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [http://pdbe.org/5bo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo2 PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [http://pdbe.org/5bo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bo2 ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).		[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
		+
		+	==See Also==
		+	*[[Phosphoribosyltransferase 3D structures\|Phosphoribosyltransferase 3D structures]]
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
	[[Category: Anthranilate phosphoribosyltransferase]]		[[Category: Anthranilate phosphoribosyltransferase]]
		+	[[Category: Large Structures]]
		+	[[Category: Mycta]]
	[[Category: Baker, E N]]		[[Category: Baker, E N]]
	[[Category: Evans, G L]]		[[Category: Evans, G L]]

OCA at 06:05, 2 June 2016

2016-06-02T06:05:33Z

←Older revision		Revision as of 06:05, 2 June 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5bo2 is ~~ON HOLD until Paper Publication~~	+	==Bianthranilate-like inhibitor with 4-atom "line" and phosphonate "hook" fishing for hydrogen bond donors in Mycobacterium tuberculosis anthranilate phosphoribosyltransferase (AnPRT; trpD)==
-		+	<StructureSection load='5bo2' size='340' side='right' caption='[[5bo2]], [[Resolution\|resolution]] 2.00Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5bo2]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BO2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BO2 FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7P1:2-[(2-CARBOXYPHENYL)AMINO]-5-(3-PHOSPHONOPROPOXY)BENZOIC+ACID'>7P1</scene>, <scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[3qr9\|3qr9]], [[4ij1\|4ij1]], [[5bo3\|5bo3]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Anthranilate_phosphoribosyltransferase Anthranilate phosphoribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.18 2.4.2.18] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bo2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bo2 OCA], [http://pdbe.org/5bo2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bo2 RCSB], [http://www.ebi.ac.uk/pdbsum/5bo2 PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/TRPD_MYCTA TRPD_MYCTA]] Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Anthranilate phosphoribosyltransferase]]
		+	[[Category: Baker, E N]]
		+	[[Category: Evans, G L]]
		+	[[Category: Lott, J S]]
		+	[[Category: Structural genomic]]
		+	[[Category: Lobenzarit-like analogue]]
		+	[[Category: Magnesium binding]]
		+	[[Category: Tbsgc]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA at 11:12, 15 May 2016

2016-05-15T11:12:01Z

←Older revision		Revision as of 11:12, 15 May 2016
Line 3:		Line 3:
	The entry 5bo2 is ON HOLD until Paper Publication		The entry 5bo2 is ON HOLD until Paper Publication

-	Authors: ~~Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Lott, J.S]]
-	[[Category: Evans, G.L]]
-	[[Category: Baker, E.N]]
-	[[Category: Tb Structural Genomics Consortium (Tbsgc)]]

OCA at 12:48, 10 June 2015

2015-06-10T12:48:46Z

←Older revision		Revision as of 12:48, 10 June 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5bo2 is ON HOLD	+	The entry 5bo2 is ON HOLD until Paper Publication

	Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)		Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)

OCA: Protected "5bo2" [edit=sysop:move=sysop]

2015-06-03T11:41:47Z

Protected "5bo2" [edit=sysop:move=sysop]

←Older revision

Revision as of 11:41, 3 June 2015

OCA: New page: '''Unreleased structure''' The entry 5bo2 is ON HOLD Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC) Description: [[Category: Unreleased Struc...

2015-06-03T11:41:46Z

New page: '''Unreleased structure''' The entry 5bo2 is ON HOLD Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC) Description: [[Category: Unreleased Struc...

New page

'''Unreleased structure'''

The entry 5bo2 is ON HOLD

Authors: Evans, G.L., Baker, E.N., Lott, J.S., TB Structural Genomics Consortium (TBSGC)

Description:
[[Category: Unreleased Structures]]
[[Category: Lott, J.S]]
[[Category: Evans, G.L]]
[[Category: Baker, E.N]]
[[Category: Tb Structural Genomics Consortium (Tbsgc)]]