5bre - Revision history

OCA at 08:29, 27 September 2023

2023-09-27T08:29:09Z

←Older revision		Revision as of 08:29, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BRE FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BRE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.5Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [https://pdbe.org/5bre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [https://www.ebi.ac.uk/pdbsum/5bre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bre ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [https://pdbe.org/5bre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [https://www.ebi.ac.uk/pdbsum/5bre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bre ProSAT]</span></td></tr>
	</table>		</table>

OCA at 06:04, 7 June 2023

2023-06-07T06:04:58Z

←Older revision		Revision as of 06:04, 7 June 2023
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	<StructureSection load='5bre' size='340' side='right'caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='5bre' size='340' side='right'caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Trycc Trycc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5BRE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_cruzi_strain_CL_Brener Trypanosoma cruzi strain CL Brener]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BRE FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [https://pdbe.org/5bre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [https://www.ebi.ac.uk/pdbsum/5bre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bre ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053510187.100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [~~http~~://pdbe.org/5bre PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5bre PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5bre ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/Q4E4E1_TRYCC Q4E4E1_TRYCC]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Glucokinase]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Trycc~~]]	+	[[Category: Trypanosoma cruzi strain CL Brener]]
-	[[Category: ~~Antonio, E L.~~D]]	+	[[Category: D'Antonio EL]]
-	[[Category: Deinema~~, M S~~]]	+	[[Category: Deinema MS]]
-	[[Category: Frey~~, T A~~]]	+	[[Category: Frey TA]]
-	[[Category: Kearns~~, S P~~]]	+	[[Category: Kearns SP]]
-	[[Category: Perry, K]]	+	[[Category: Perry K]]
-	~~[[Category: Hexose kinase]]~~	+
-	~~[[Category: Transferase]]~~	+
-	~~[[Category: Transferase-transferase inhibitor complex~~]]	+

OCA at 11:05, 25 December 2019

2019-12-25T11:05:35Z

←Older revision		Revision as of 11:05, 25 December 2019
Line 1:		Line 1:

	==Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN==		==Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN==
-	<StructureSection load='5bre' size='340' side='right' caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>	+	<StructureSection load='5bre' size='340' side='right'caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BRE FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BRE FirstGlance]. <br>
Line 24:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Glucokinase]]		[[Category: Glucokinase]]
		+	[[Category: Large Structures]]
	[[Category: Trycc]]		[[Category: Trycc]]
	[[Category: Antonio, E L.D]]		[[Category: Antonio, E L.D]]

OCA at 12:23, 6 November 2017

2017-11-06T12:23:25Z

←Older revision		Revision as of 12:23, 6 November 2017
Line 1:		Line 1:
		+
	==Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN==		==Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN==
	<StructureSection load='5bre' size='340' side='right' caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>		<StructureSection load='5bre' size='340' side='right' caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BRE FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Trycc Trycc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BRE FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">Tc00.1047053510187.100 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=353153 TRYCC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://pdbe.org/5bre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://pdbe.org/5bre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bre ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
Line 22:		Line 24:
	</StructureSection>		</StructureSection>
	[[Category: Glucokinase]]		[[Category: Glucokinase]]
		+	[[Category: Trycc]]
	[[Category: Antonio, E L.D]]		[[Category: Antonio, E L.D]]
	[[Category: Deinema, M S]]		[[Category: Deinema, M S]]

OCA at 07:40, 3 February 2016

2016-02-03T07:40:26Z

←Older revision		Revision as of 07:40, 3 February 2016
Line 8:		Line 8:
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://pdbe.org/5bre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://pdbe.org/5bre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Glucokinase and hexokinase from pathogenic protozoa Trypanosoma cruzi are potential drug targets for antiparasitic chemotherapy of Chagas' disease. These glucose kinases phosphorylate d-glucose with co-substrate ATP and yield glucose 6-phosphate and are involved in essential metabolic pathways, such as glycolysis and the pentose phosphate pathway. An inhibitor class was conceived that is selective for T. cruzi glucokinase (TcGlcK) using structure-based drug design involving glucosamine having a linker from the C2 amino that terminates with a hydrophobic group either being phenyl, p-hydroxyphenyl, or dioxobenzo[b]thiophenyl groups. The synthesis and characterization for two of the four compounds are presented while the other two compounds were commercially available. Four high-resolution X-ray crystal structures of TcGlcK inhibitor complexes are reported along with enzyme inhibition constants (Ki) for TcGlcK and Homo sapiens hexokinase IV (HsHxKIV). These glucosamine analogue inhibitors include three strongly selective TcGlcK inhibitors and a fourth inhibitor, benzoyl glucosamine (BENZ-GlcN), which is a similar variant exhibiting a shorter linker. Carboxybenzyl glucosamine (CBZ-GlcN) was found to be the strongest glucokinase inhibitor known to date, having a Ki of 0.71+/-0.05muM. Also reported are two biologically active inhibitors against in vitro T. cruzi culture that were BENZ-GlcN and CBZ-GlcN, with intracellular amastigote growth inhibition IC50 values of 16.08+/-0.16muM and 48.73+/-0.69muM, respectively. These compounds revealed little to no toxicity against mammalian NIH-3T3 fibroblasts and provide a key starting point for further drug development with this class of compound.
		+
		+	Structure-based approach to the identification of a novel group of selective glucosamine analogue inhibitors of Trypanosoma cruzi glucokinase.,D'Antonio EL, Deinema MS, Kearns SP, Frey TA, Tanghe S, Perry K, Roy TA, Gracz HS, Rodriguez A, D'Antonio J Mol Biochem Parasitol. 2016 Jan 14;204(2):64-76. doi:, 10.1016/j.molbiopara.2015.12.004. PMID:26778112<ref>PMID:26778112</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5bre" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:21, 23 December 2015

2015-12-23T06:21:19Z

←Older revision		Revision as of 06:21, 23 December 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://pdbe.org/5bre PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>
	</table>		</table>
	__TOC__		__TOC__

OCA at 15:35, 17 June 2015

2015-06-17T15:35:22Z

←Older revision		Revision as of 15:35, 17 June 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN==
-		+	<StructureSection load='5bre' size='340' side='right' caption='[[5bre]], [[Resolution\|resolution]] 2.50Å' scene=''>
-	~~The entry~~ 5bre is ~~ON HOLD~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5bre]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BRE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BRE FirstGlance]. <br>
-	~~Authors~~: D'~~Antonio~~, E.L., ~~Perry, K~~.~~, Deinema, M~~.S., ~~Kearns~~, S.P., ~~Frey, T~~.A.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4UZ:2-{[(BENZYLOXY)CARBONYL]AMINO}-2-DEOXY-BETA-D-GLUCOPYRANOSE'>4UZ</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2q2r\|2q2r]], [[5brd\|5brd]], [[5brf\|5brf]], [[5brh\|5brh]]</td></tr>
-	~~Description~~: ~~Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bre OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bre RCSB], [http://www.ebi.ac.uk/pdbsum/5bre PDBsum]</span></td></tr>
-	[[Category: Deinema, M.S]]	+	</table>
-	[[Category: Frey, T.A]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Glucokinase]]
		+	[[Category: Antonio, E L.D]]
		+	[[Category: Deinema, M S]]
		+	[[Category: Frey, T A]]
		+	[[Category: Kearns, S P]]
	[[Category: Perry, K]]		[[Category: Perry, K]]
-	[[Category: ~~Kearns, S.P~~]]	+	[[Category: Hexose kinase]]
-	[[Category: ~~D'Antonio, E.L~~]]	+	[[Category: Transferase]]
		+	[[Category: Transferase-transferase inhibitor complex]]

OCA: Protected "5bre" [edit=sysop:move=sysop]

2015-06-10T12:56:19Z

Protected "5bre" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:56, 10 June 2015

OCA: New page: '''Unreleased structure''' The entry 5bre is ON HOLD Authors: D'Antonio, E.L., Perry, K., Deinema, M.S., Kearns, S.P., Frey, T.A. Description: Crystal structure of Trypanosoma cruzi gl...

2015-06-10T12:56:18Z

New page: '''Unreleased structure''' The entry 5bre is ON HOLD Authors: D'Antonio, E.L., Perry, K., Deinema, M.S., Kearns, S.P., Frey, T.A. Description: Crystal structure of Trypanosoma cruzi gl...

New page

'''Unreleased structure'''

The entry 5bre is ON HOLD

Authors: D'Antonio, E.L., Perry, K., Deinema, M.S., Kearns, S.P., Frey, T.A.

Description: Crystal structure of Trypanosoma cruzi glucokinase in complex with inhibitor CBZ-GlcN
[[Category: Unreleased Structures]]
[[Category: Deinema, M.S]]
[[Category: Frey, T.A]]
[[Category: Perry, K]]
[[Category: Kearns, S.P]]
[[Category: D'Antonio, E.L]]