5bwj - Revision history

OCA at 12:18, 6 March 2024

2024-03-06T12:18:19Z

←Older revision		Revision as of 12:18, 6 March 2024
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.054Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [https://pdbe.org/5bwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [https://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [https://pdbe.org/5bwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [https://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/O51381_BORBU O51381_BORBU]		[https://www.uniprot.org/uniprot/O51381_BORBU O51381_BORBU]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	Two-component signal transduction systems are the primary mechanisms by which bacteria perceive and respond to changes in their environment. The Hk1/Rrp1 two-component system (TCS) in Borrelia burgdorferi consists of a hybrid histidine kinase and a response regulator with diguanylate cyclase activity, respectively. Phosphorylated Rrp1 catalyzes the synthesis of c-di-GMP, a second messenger associated with bacterial life-style control networks. Spirochetes lacking either Hk1 or Rrp1 are virulent in mice but destroyed within feeding ticks. Activation of Hk1 by exogenous stimuli represents the seminal event for c-di-GMP signaling. We reasoned that structural characterization of Hk1's sensor would provide insights into the mechanism underlying signal transduction and aid in the identification of activating ligands. The Hk1 sensor is composed of three ligand-binding domains (D1-3), each with homology to periplasmic solute-binding proteins (PBPs) typically associated with ABC transporters. Herein, we determined the structure for D1, the most N-terminal PBP domain. As expected, D1 displays a bilobed Venus Fly Trap-fold. Similar to the prototypical sensor PBPs HK29S from Geobacter sulfurreducens and VFT2 from Bordetella pertussis, apo-D1 adopts a closed conformation. Using complementary approaches, including SAXS, we established that D1 forms a dimer in solution. The D1 structure enabled us to model the D2 and D3 domains. Differences in the ligand-binding pockets suggest that each PBP recognizes a different ligand. The ability of Hk1 to recognize multiple stimuli provides spirochetes with a means of distinguishing between the acquisition and transmission blood meals and generate a graded output response that is reflective of the perceived environmental threats.
-
-	Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.,Bauer WJ, Luthra A, Zhu G, Radolf JD, Malkowski MG, Caimano MJ J Struct Biol. 2015 Aug 28. pii: S1047-8477(15)30051-4. doi:, 10.1016/j.jsb.2015.08.013. PMID:26321039<ref>PMID:26321039</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5bwj" style="background-color:#fffaf0;"></div>
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:11, 7 June 2023

2023-06-07T06:11:12Z

←Older revision		Revision as of 06:11, 7 June 2023
Line 3:		Line 3:
	<StructureSection load='5bwj' size='340' side='right'caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='5bwj' size='340' side='right'caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Borbu Borbu~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Borreliella_burgdorferi_B31 Borreliella burgdorferi B31]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0420 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 BORBU])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [https://pdbe.org/5bwj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [https://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [~~http~~://pdbe.org/5bwj PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/O51381_BORBU O51381_BORBU]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 21:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Borbu~~]]	+	[[Category: Borreliella burgdorferi B31]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Bauer~~, W J~~]]	+	[[Category: Bauer WJ]]
-	[[Category: Caimano~~, M J~~]]	+	[[Category: Caimano MJ]]
-	[[Category: Luthra, A]]	+	[[Category: Luthra A]]
-	[[Category: Malkowski~~, M G~~]]	+	[[Category: Malkowski MG]]
-	[[Category: Radolf~~, J D~~]]	+	[[Category: Radolf JD]]
-	[[Category: Zhu, G]]	+	[[Category: Zhu G]]
-	~~[[Category: Lyme disease]]~~	+
-	~~[[Category: Periplasmic sensor domain]]~~	+
-	~~[[Category: Signaling protein]]~~	+
-	~~[[Category: Venus fly trap fold~~]]	+

OCA at 15:58, 11 December 2019

2019-12-11T15:58:40Z

←Older revision		Revision as of 15:58, 11 December 2019
Line 1:		Line 1:

	==Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor==		==Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor==
-	<StructureSection load='5bwj' size='340' side='right' caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>	+	<StructureSection load='5bwj' size='340' side='right'caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Borbu Borbu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">BB_0420 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224326 BORBU])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://pdbe.org/5bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://pdbe.org/5bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>
	</table>		</table>
Line 20:		Line 21:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Borbu]]
		+	[[Category: Large Structures]]
	[[Category: Bauer, W J]]		[[Category: Bauer, W J]]
	[[Category: Caimano, M J]]		[[Category: Caimano, M J]]

OCA at 04:42, 21 September 2017

2017-09-21T04:42:42Z

←Older revision		Revision as of 04:42, 21 September 2017
Line 1:		Line 1:
		+
	==Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor==		==Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor==
	<StructureSection load='5bwj' size='340' side='right' caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>		<StructureSection load='5bwj' size='340' side='right' caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>
Line 4:		Line 5:
	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://pdbe.org/5bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://pdbe.org/5bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bwj ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 07:53, 30 September 2015

2015-09-30T07:53:16Z

←Older revision		Revision as of 07:53, 30 September 2015
Line 4:		Line 4:
	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://pdbe.org/5bwj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Two-component signal transduction systems are the primary mechanisms by which bacteria perceive and respond to changes in their environment. The Hk1/Rrp1 two-component system (TCS) in Borrelia burgdorferi consists of a hybrid histidine kinase and a response regulator with diguanylate cyclase activity, respectively. Phosphorylated Rrp1 catalyzes the synthesis of c-di-GMP, a second messenger associated with bacterial life-style control networks. Spirochetes lacking either Hk1 or Rrp1 are virulent in mice but destroyed within feeding ticks. Activation of Hk1 by exogenous stimuli represents the seminal event for c-di-GMP signaling. We reasoned that structural characterization of Hk1's sensor would provide insights into the mechanism underlying signal transduction and aid in the identification of activating ligands. The Hk1 sensor is composed of three ligand-binding domains (D1-3), each with homology to periplasmic solute-binding proteins (PBPs) typically associated with ABC transporters. Herein, we determined the structure for D1, the most N-terminal PBP domain. As expected, D1 displays a bilobed Venus Fly Trap-fold. Similar to the prototypical sensor PBPs HK29S from Geobacter sulfurreducens and VFT2 from Bordetella pertussis, apo-D1 adopts a closed conformation. Using complementary approaches, including SAXS, we established that D1 forms a dimer in solution. The D1 structure enabled us to model the D2 and D3 domains. Differences in the ligand-binding pockets suggest that each PBP recognizes a different ligand. The ability of Hk1 to recognize multiple stimuli provides spirochetes with a means of distinguishing between the acquisition and transmission blood meals and generate a graded output response that is reflective of the perceived environmental threats.
		+
		+	Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor: A system for sensing small molecules associated with tick feeding.,Bauer WJ, Luthra A, Zhu G, Radolf JD, Malkowski MG, Caimano MJ J Struct Biol. 2015 Aug 28. pii: S1047-8477(15)30051-4. doi:, 10.1016/j.jsb.2015.08.013. PMID:26321039<ref>PMID:26321039</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5bwj" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 14:54, 29 July 2015

2015-07-29T14:54:31Z

←Older revision		Revision as of 14:54, 29 July 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor==
-		+	<StructureSection load='5bwj' size='340' side='right' caption='[[5bwj]], [[Resolution\|resolution]] 2.05Å' scene=''>
-	~~The entry~~ 5bwj is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5bwj]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BWJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BWJ FirstGlance]. <br>
-	~~Authors~~: ~~Bauer~~, W.J.~~, Luthra, A~~.~~, Zhu, G~~., ~~Radolf, J~~.D., ~~Malkowski, M~~.G., ~~Caimano, M~~.J.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
-		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bwj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bwj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5bwj RCSB], [http://www.ebi.ac.uk/pdbsum/5bwj PDBsum]</span></td></tr>
-	~~Description: Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor~~	+	</table>
-	[[Category: ~~Unreleased Structures~~]]	+	__TOC__
-	[[Category: ~~Radolf~~, J.D]]	+	</StructureSection>
		+	[[Category: Bauer, W J]]
		+	[[Category: Caimano, M J]]
	[[Category: Luthra, A]]		[[Category: Luthra, A]]
-	[[Category: ~~Bauer~~, W.J]]	+	[[Category: Malkowski, M G]]
		+	[[Category: Radolf, J D]]
	[[Category: Zhu, G]]		[[Category: Zhu, G]]
-	[[Category: ~~Caimano, M.J~~]]	+	[[Category: Lyme disease]]
-	[[Category: ~~Malkowski, M.G~~]]	+	[[Category: Periplasmic sensor domain]]
		+	[[Category: Signaling protein]]
		+	[[Category: Venus fly trap fold]]

OCA at 11:45, 24 June 2015

2015-06-24T11:45:10Z

←Older revision		Revision as of 11:45, 24 June 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5bwj is ON HOLD	+	The entry 5bwj is ON HOLD until Paper Publication

	Authors: Bauer, W.J., Luthra, A., Zhu, G., Radolf, J.D., Malkowski, M.G., Caimano, M.J.		Authors: Bauer, W.J., Luthra, A., Zhu, G., Radolf, J.D., Malkowski, M.G., Caimano, M.J.

OCA: Protected "5bwj" [edit=sysop:move=sysop]

2015-06-17T13:59:29Z

Protected "5bwj" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:59, 17 June 2015

OCA: New page: '''Unreleased structure''' The entry 5bwj is ON HOLD Authors: Bauer, W.J., Luthra, A., Zhu, G., Radolf, J.D., Malkowski, M.G., Caimano, M.J. Description: Structural characterization an...

2015-06-17T13:59:28Z

New page: '''Unreleased structure''' The entry 5bwj is ON HOLD Authors: Bauer, W.J., Luthra, A., Zhu, G., Radolf, J.D., Malkowski, M.G., Caimano, M.J. Description: Structural characterization an...

New page

'''Unreleased structure'''

The entry 5bwj is ON HOLD

Authors: Bauer, W.J., Luthra, A., Zhu, G., Radolf, J.D., Malkowski, M.G., Caimano, M.J.

Description: Structural characterization and modeling of the Borrelia burgdorferi hybrid histidine kinase Hk1 periplasmic sensor
[[Category: Unreleased Structures]]
[[Category: Radolf, J.D]]
[[Category: Luthra, A]]
[[Category: Bauer, W.J]]
[[Category: Zhu, G]]
[[Category: Caimano, M.J]]
[[Category: Malkowski, M.G]]