5chz - Revision history

OCA at 08:38, 27 September 2023

2023-09-27T08:38:06Z

←Older revision		Revision as of 08:38, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.83Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [https://pdbe.org/5chz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [https://www.ebi.ac.uk/pdbsum/5chz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [https://pdbe.org/5chz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [https://www.ebi.ac.uk/pdbsum/5chz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:07, 14 June 2023

2023-06-14T12:07:24Z

←Older revision		Revision as of 12:07, 14 June 2023
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	<StructureSection load='5chz' size='340' side='right'caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='5chz' size='340' side='right'caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ofa\|4ofa]], [[4ofe\|4ofe]], [[4ofh\|4ofh]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [https://pdbe.org/5chz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [https://www.ebi.ac.uk/pdbsum/5chz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>
-	~~<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MBD4, MED1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [~~http~~://pdbe.org/5chz PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5chz PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref>	+	[https://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref>

	==See Also==		==See Also==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Lee, S]]	+	[[Category: Synthetic construct]]
-	[[Category: Lin, Y L]]	+	[[Category: Lee S]]
-	[[Category: Ouzon-Shubeita, H]]	+	[[Category: Lin Y-L]]
-	~~[[Category: Dna glycosylase]]~~	+	[[Category: Ouzon-Shubeita H]]
-	~~[[Category: G:t mismatch]]~~	+
-	~~[[Category: Hmbd4]]~~	+
-	~~[[Category: Hydrolase-dna complex~~]]	+

OCA at 08:47, 18 December 2019

2019-12-18T08:47:11Z

←Older revision		Revision as of 08:47, 18 December 2019
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	==Structure of wild-type human MBD4 bound to a G:T mismatch==		==Structure of wild-type human MBD4 bound to a G:T mismatch==
-	<StructureSection load='5chz' size='340' side='right' caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>	+	<StructureSection load='5chz' size='340' side='right'caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref>		[[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref>
		+
		+	==See Also==
		+	*[[Methyl CpG binding protein 3D structures\|Methyl CpG binding protein 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
Line 16:		Line 19:
	</StructureSection>		</StructureSection>
	[[Category: Human]]		[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Lee, S]]		[[Category: Lee, S]]
	[[Category: Lin, Y L]]		[[Category: Lin, Y L]]

OCA at 12:28, 6 November 2017

2017-11-06T12:28:03Z

←Older revision		Revision as of 12:28, 6 November 2017
Line 3:		Line 3:
	<StructureSection load='5chz' size='340' side='right' caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>		<StructureSection load='5chz' size='340' side='right' caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ofa\|4ofa]], [[4ofe\|4ofe]], [[4ofh\|4ofh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ofa\|4ofa]], [[4ofe\|4ofe]], [[4ofh\|4ofh]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">MBD4, MED1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [http://pdbe.org/5chz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [http://www.ebi.ac.uk/pdbsum/5chz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [http://pdbe.org/5chz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [http://www.ebi.ac.uk/pdbsum/5chz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>
	</table>		</table>
Line 14:		Line 15:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
	[[Category: Lee, S]]		[[Category: Lee, S]]
	[[Category: Lin, Y L]]		[[Category: Lin, Y L]]

OCA at 15:27, 26 July 2016

2016-07-26T15:27:37Z

←Older revision		Revision as of 15:27, 26 July 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5chz is ~~ON HOLD~~ ~~until Jul 20 2017~~	+	==Structure of wild-type human MBD4 bound to a G:T mismatch==
-		+	<StructureSection load='5chz' size='340' side='right' caption='[[5chz]], [[Resolution\|resolution]] 1.83Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5chz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CHZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CHZ FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4ofa\|4ofa]], [[4ofe\|4ofe]], [[4ofh\|4ofh]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5chz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5chz OCA], [http://pdbe.org/5chz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5chz RCSB], [http://www.ebi.ac.uk/pdbsum/5chz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5chz ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/MBD4_HUMAN MBD4_HUMAN]] Mismatch-specific DNA N-glycosylase involved in DNA repair. Has thymine glycosylase activity and is specific for G:T mismatches within methylated and unmethylated CpG sites. Can also remove uracil or 5-fluorouracil in G:U mismatches. Has no lyase activity. Was first identified as methyl-CpG-binding protein.<ref>PMID:10097147</ref> <ref>PMID:10930409</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Lee, S]]
		+	[[Category: Lin, Y L]]
		+	[[Category: Ouzon-Shubeita, H]]
		+	[[Category: Dna glycosylase]]
		+	[[Category: G:t mismatch]]
		+	[[Category: Hmbd4]]
		+	[[Category: Hydrolase-dna complex]]

OCA at 04:49, 14 July 2016

2016-07-14T04:49:36Z

←Older revision		Revision as of 04:49, 14 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5chz is ON HOLD until ~~Paper Publication~~	+	The entry 5chz is ON HOLD until Jul 20 2017

	Authors:		Authors:

OCA at 11:29, 15 May 2016

2016-05-15T11:29:19Z

←Older revision		Revision as of 11:29, 15 May 2016
Line 3:		Line 3:
	The entry 5chz is ON HOLD until Paper Publication		The entry 5chz is ON HOLD until Paper Publication

-	Authors: ~~Ouzon-Shubeita, H., Lin, Y.-L., Lee, S.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Lin, Y.-L]]
-	[[Category: Ouzon-Shubeita, H]]
-	[[Category: Lee, S]]

OCA at 10:32, 16 December 2015

2015-12-16T10:32:40Z

←Older revision		Revision as of 10:32, 16 December 2015
Line 8:		Line 8:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
	[[Category: Lin, Y.-L]]		[[Category: Lin, Y.-L]]
-	[[Category: Lee, S]]
	[[Category: Ouzon-Shubeita, H]]		[[Category: Ouzon-Shubeita, H]]
		+	[[Category: Lee, S]]

OCA: Protected "5chz" [edit=sysop:move=sysop]

2015-07-22T13:09:19Z

Protected "5chz" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:09, 22 July 2015

OCA: New page: '''Unreleased structure''' The entry 5chz is ON HOLD until Paper Publication Authors: Ouzon-Shubeita, H., Lin, Y.-L., Lee, S. Description: Category: Unreleased Structures [[Catego...

2015-07-22T13:09:17Z

New page: '''Unreleased structure''' The entry 5chz is ON HOLD until Paper Publication Authors: Ouzon-Shubeita, H., Lin, Y.-L., Lee, S. Description: Category: Unreleased Structures [[Catego...

New page

'''Unreleased structure'''

The entry 5chz is ON HOLD until Paper Publication

Authors: Ouzon-Shubeita, H., Lin, Y.-L., Lee, S.

Description:
[[Category: Unreleased Structures]]
[[Category: Lin, Y.-L]]
[[Category: Lee, S]]
[[Category: Ouzon-Shubeita, H]]