5cjw - Revision history

OCA at 08:38, 27 September 2023

2023-09-27T08:38:32Z

←Older revision		Revision as of 08:38, 27 September 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans_CH34 Cupriavidus metallidurans CH34]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CJW FirstGlance]. <br>		<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans_CH34 Cupriavidus metallidurans CH34]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CJW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.4Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [https://pdbe.org/5cjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [https://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [https://pdbe.org/5cjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [https://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:10, 14 June 2023

2023-06-14T12:10:04Z

←Older revision		Revision as of 12:10, 14 June 2023
Line 3:		Line 3:
	<StructureSection load='5cjw' size='340' side='right'caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='5cjw' size='340' side='right'caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Cupmc Cupmc~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5CJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Cupriavidus_metallidurans_CH34 Cupriavidus metallidurans CH34]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CJW FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [https://pdbe.org/5cjw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [https://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sbm, Rmet_0210 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266264 CUPMC])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [~~http~~://pdbe.org/5cjw PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/ICMF_CUPMC ICMF_CUPMC] Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, and to a much lesser extent, of pivalyl-CoA and isovaleryl-CoA, using radical chemistry (PubMed:22167181). Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly (PubMed:22167181, PubMed:25675500). The G-domain of IcmF has also a role in its cofactor repair (PubMed:28130442). Does not display ATPase activity.<ref>PMID:22167181</ref> <ref>PMID:25675500</ref> <ref>PMID:28130442</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 22:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Cupmc~~]]	+	[[Category: Cupriavidus metallidurans CH34]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Methylmalonyl-CoA mutase]]~~	+	[[Category: Drennan CL]]
-	[[Category: Drennan~~, C L~~]]	+	[[Category: Jost M]]
-	[[Category: Jost, M]]	+
-	~~[[Category: Complex]]~~	+
-	~~[[Category: G-protein chaperone]]~~	+
-	~~[[Category: Isomerase]]~~	+
-	~~[[Category: Radical enzyme~~]]	+

OCA at 16:07, 20 November 2019

2019-11-20T16:07:45Z

←Older revision		Revision as of 16:07, 20 November 2019
Line 1:		Line 1:

	==Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A==		==Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A==
-	<StructureSection load='5cjw' size='340' side='right' caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>	+	<StructureSection load='5cjw' size='340' side='right'caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CJW FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Cupmc Cupmc]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CJW FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">sbm, Rmet_0210 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=266264 CUPMC])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://pdbe.org/5cjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://pdbe.org/5cjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Cupmc]]
		+	[[Category: Large Structures]]
	[[Category: Methylmalonyl-CoA mutase]]		[[Category: Methylmalonyl-CoA mutase]]
	[[Category: Drennan, C L]]		[[Category: Drennan, C L]]

OCA at 10:40, 13 September 2017

2017-09-13T10:40:57Z

←Older revision		Revision as of 10:40, 13 September 2017
Line 1:		Line 1:
		+
	==Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A==		==Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A==
	<StructureSection load='5cjw' size='340' side='right' caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>		<StructureSection load='5cjw' size='340' side='right' caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>
Line 6:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://pdbe.org/5cjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://pdbe.org/5cjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cjw ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 06:35, 30 September 2015

2015-09-30T06:35:27Z

←Older revision		Revision as of 06:35, 30 September 2015
Line 6:		Line 6:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://pdbe.org/5cjw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Acyl-CoA mutases are a growing class of adenosylcobalamin-dependent radical enzymes that perform challenging carbon skeleton rearrangements in primary and secondary metabolism. Members of this class of enzymes must precisely control substrate positioning to prevent oxidative interception of radical intermediates during catalysis. Our understanding of substrate specificity and catalysis in acyl-CoA mutases, however, is incomplete. Here, we present crystal structures of IcmF, a natural fusion protein variant of isobutyryl-CoA mutase, in complex with the adenosylcobalamin cofactor and four different acyl-CoA substrates. These structures demonstrate how the active site is designed to accommodate the aliphatic acyl chains of each substrate. The structures suggest that a conformational change of the 5'-deoxyadenosyl group from C2'-endo to C3'-endo could contribute to initiation of catalysis. Furthermore, detailed bioinformatic analyses guided by our structural findings identify critical determinants of acyl-CoA mutase substrate specificity and predict new acyl-CoA mutase-catalyzed reactions. These results expand our understanding of substrate specificity and catalytic scope of acyl-CoA mutases and could benefit engineering efforts for biotechnological applications ranging from production of biofuels and commercial products to hydrocarbon remediation.
		+
		+	Structural Basis for Substrate Specificity in Adenosylcobalamin-Dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.,Jost M, Born DA, Cracan V, Banerjee R, Drennan CL J Biol Chem. 2015 Aug 28. pii: jbc.M115.676890. PMID:26318610<ref>PMID:26318610</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5cjw" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 11:24, 9 September 2015

2015-09-09T11:24:03Z

←Older revision		Revision as of 11:24, 9 September 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A==
-		+	<StructureSection load='5cjw' size='340' side='right' caption='[[5cjw]], [[Resolution\|resolution]] 3.40Å' scene=''>
-	~~The entry~~ 5cjw is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5cjw]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CJW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CJW FirstGlance]. <br>
-	~~Authors~~: ~~Jost~~, M., ~~Drennan~~, C.L.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=52O:PIVALYL-COENZYME+A'>52O</scene>, <scene name='pdbligand=5AD:5-DEOXYADENOSINE'>5AD</scene>, <scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4xc6\|4xc6]], [[4xc7\|4xc7]], [[4xc8\|4xc8]], [[5cju\|5cju]], [[5cjt\|5cjt]], [[5cjv\|5cjv]]</td></tr>
-	~~Description:~~	+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methylmalonyl-CoA_mutase Methylmalonyl-CoA mutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.99.2 5.4.99.2] </span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cjw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cjw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=5cjw RCSB], [http://www.ebi.ac.uk/pdbsum/5cjw PDBsum]</span></td></tr>
-	[[Category: Drennan, C.L]]	+	</table>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Methylmalonyl-CoA mutase]]
		+	[[Category: Drennan, C L]]
	[[Category: Jost, M]]		[[Category: Jost, M]]
		+	[[Category: Complex]]
		+	[[Category: G-protein chaperone]]
		+	[[Category: Isomerase]]
		+	[[Category: Radical enzyme]]

OCA at 13:29, 29 July 2015

2015-07-29T13:29:44Z

←Older revision		Revision as of 13:29, 29 July 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5cjw is ON HOLD	+	The entry 5cjw is ON HOLD until Paper Publication

	Authors: Jost, M., Drennan, C.L.		Authors: Jost, M., Drennan, C.L.

OCA: Protected "5cjw" [edit=sysop:move=sysop]

2015-07-22T13:14:16Z

Protected "5cjw" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:14, 22 July 2015

OCA: New page: '''Unreleased structure''' The entry 5cjw is ON HOLD Authors: Jost, M., Drennan, C.L. Description: Category: Unreleased Structures Category: Drennan, C.L Category: Jost, M

2015-07-22T13:14:15Z

New page: '''Unreleased structure''' The entry 5cjw is ON HOLD Authors: Jost, M., Drennan, C.L. Description: Category: Unreleased Structures Category: Drennan, C.L Category: Jost, M

New page

'''Unreleased structure'''

The entry 5cjw is ON HOLD

Authors: Jost, M., Drennan, C.L.

Description:
[[Category: Unreleased Structures]]
[[Category: Drennan, C.L]]
[[Category: Jost, M]]