5cnt - Revision history

OCA at 08:39, 27 September 2023

2023-09-27T08:39:32Z

←Older revision		Revision as of 08:39, 27 September 2023
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	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CNT FirstGlance]. <br>		<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.25Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [https://pdbe.org/5cnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [https://www.ebi.ac.uk/pdbsum/5cnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnt ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [https://pdbe.org/5cnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [https://www.ebi.ac.uk/pdbsum/5cnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnt ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:19, 14 June 2023

2023-06-14T12:19:32Z

←Older revision		Revision as of 12:19, 14 June 2023
Line 3:		Line 3:
	<StructureSection load='5cnt' size='340' side='right'caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>		<StructureSection load='5cnt' size='340' side='right'caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Ecoli Ecoli~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5CNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CNT FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene~~></td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cns\|5cns]], [[5cnu\|5cnu]], [[5cnv\|5cnv]]</td></tr>~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [https://pdbe.org/5cnt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [https://www.ebi.ac.uk/pdbsum/5cnt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnt ProSAT]</span></td></tr>
-	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nrdA, dnaF, b2234, JW2228 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), nrdB, ftsB, b2235, JW2229 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>	+
-	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>	+
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [~~http~~://pdbe.org/5cnt PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5cnt PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnt ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/RIR1_ECOLI RIR1_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. [[http://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.	+	[https://www.uniprot.org/uniprot/RIR1_ECOLI RIR1_ECOLI] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines.
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 20:

	==See Also==		==See Also==
-	*[[Ribonucleotide reductase\|Ribonucleotide reductase]]	+	*[[Ribonucleotide reductase 3D structures\|Ribonucleotide reductase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Ecoli~~]]	+	[[Category: Escherichia coli K-12]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Ribonucleoside~~-~~diphosphate reductase]]~~	+	[[Category: Chen PY-T]]
-	~~[[Category: Chen, P Y.~~T]]	+	[[Category: Drennan CL]]
-	[[Category: Drennan~~, C L~~]]	+	[[Category: Funk MA]]
-	[[Category: Funk~~, M A~~]]	+	[[Category: Zimanyi CM]]
-	[[Category: Zimanyi~~, C M]]~~	+
-	~~[[Category: Allostery]]~~	+
-	~~[[Category: Nucleotide metabolism]]~~	+
-	~~[[Category: Oxidoreductase]]~~	+
-	~~[[Category: Ribonucleotide reductase]]~~	+
-	~~[[Category: Substrate specificity~~]]	+

OCA at 07:29, 27 November 2019

2019-11-27T07:29:43Z

←Older revision		Revision as of 07:29, 27 November 2019
Line 1:		Line 1:

	==Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution==		==Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution==
-	<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>	+	<StructureSection load='5cnt' size='340' side='right'caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNT FirstGlance]. <br>		<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNT FirstGlance]. <br>
Line 21:		Line 21:
	</div>		</div>
	<div class="pdbe-citations 5cnt" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5cnt" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ribonucleotide reductase\|Ribonucleotide reductase]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 29:
	</StructureSection>		</StructureSection>
	[[Category: Ecoli]]		[[Category: Ecoli]]
		+	[[Category: Large Structures]]
	[[Category: Ribonucleoside-diphosphate reductase]]		[[Category: Ribonucleoside-diphosphate reductase]]
	[[Category: Chen, P Y.T]]		[[Category: Chen, P Y.T]]

OCA at 16:38, 15 November 2017

2017-11-15T16:38:00Z

←Older revision		Revision as of 16:38, 15 November 2017
Line 3:		Line 3:
	<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>		<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNT FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNT FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cns\|5cns]], [[5cnu\|5cnu]], [[5cnv\|5cnv]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cns\|5cns]], [[5cnu\|5cnu]], [[5cnv\|5cnv]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">nrdA, dnaF, b2234, JW2228 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI]), nrdB, ftsB, b2235, JW2229 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [http://pdbe.org/5cnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [http://www.ebi.ac.uk/pdbsum/5cnt PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [http://pdbe.org/5cnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [http://www.ebi.ac.uk/pdbsum/5cnt PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cnt ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 24:		Line 25:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Ecoli]]
	[[Category: Ribonucleoside-diphosphate reductase]]		[[Category: Ribonucleoside-diphosphate reductase]]
	[[Category: Chen, P Y.T]]		[[Category: Chen, P Y.T]]

OCA at 05:12, 11 May 2016

2016-05-11T05:12:58Z

←Older revision		Revision as of 05:12, 11 May 2016
Line 1:		Line 1:
		+
	==Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution==		==Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution==
	<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>		<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>

OCA at 17:05, 20 January 2016

2016-01-20T17:05:40Z

←Older revision		Revision as of 17:05, 20 January 2016
Line 1:		Line 1:
-	'''~~Unreleased~~ structure'''	+	==Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution==
		+	<StructureSection load='5cnt' size='340' side='right' caption='[[5cnt]], [[Resolution\|resolution]] 3.25Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5cnt]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CNT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CNT FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DTP:2-DEOXYADENOSINE+5-TRIPHOSPHATE'>DTP</scene>, <scene name='pdbligand=FEO:MU-OXO-DIIRON'>FEO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5cns\|5cns]], [[5cnu\|5cnu]], [[5cnv\|5cnv]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ribonucleoside-diphosphate_reductase Ribonucleoside-diphosphate reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.17.4.1 1.17.4.1] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cnt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cnt OCA], [http://pdbe.org/5cnt PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cnt RCSB], [http://www.ebi.ac.uk/pdbsum/5cnt PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/RIR1_ECOLI RIR1_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R1 contains the binding sites for both substrates and allosteric effectors and carries out the actual reduction of the ribonucleotide. It also provides redox-active cysteines. [[http://www.uniprot.org/uniprot/RIR2_ECOLI RIR2_ECOLI]] Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. R2 contains the tyrosyl radical required for catalysis.
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Ribonucleotide reductase (RNR) converts ribonucleotides to deoxyribonucleotides, a reaction that is essential for DNA biosynthesis and repair. This enzyme is responsible for reducing all four ribonucleotide substrates, with specificity regulated by the binding of an effector to a distal allosteric site. In all characterized RNRs, the binding of effector dATP alters the active site to select for pyrimidines over purines, whereas effectors dGTP and TTP select for substrates ADP and GDP, respectively. Here, we have determined structures of Escherichia coli class Ia RNR with all four substrate/specificity effector-pairs bound (CDP/dATP, UDP/dATP, ADP/dGTP, GDP/TTP) that reveal the conformational rearrangements responsible for this remarkable allostery. These structures delineate how RNR 'reads' the base of each effector and communicates substrate preference to the active site by forming differential hydrogen bonds, thereby maintaining the proper balance of deoxynucleotides in the cell.

-	~~The entry 5cnt is ON HOLD until Paper Publication~~	+	Molecular basis for allosteric specificity regulation in class Ia ribonucleotide reductase from Escherichia coli.,Zimanyi CM, Chen PY, Kang G, Funk MA, Drennan CL Elife. 2016 Jan 12;5. pii: e07141. doi: 10.7554/eLife.07141. PMID:26754917<ref>PMID:26754917</ref>

-	~~Authors: Chen~~, P.Y.~~-T., Zimanyi, C.M., Funk, M.A., Drennan, C.L~~.	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-		+	</div>
-	~~Description: Crystal structure of the dATP inhibited E. coli~~ class ~~Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution~~	+	<div class="pdbe-citations 5cnt" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Unreleased Structures~~]]	+	== References ==
-	[[Category: ~~Funk~~, M.A]]	+	<references/>
-	[[Category: Drennan, C.L]]	+	__TOC__
-	[[Category: ~~Chen~~, ~~P.Y.-T~~]]	+	</StructureSection>
-	[[Category: Zimanyi, C.M]]	+	[[Category: Ribonucleoside-diphosphate reductase]]
		+	[[Category: Chen, P Y.T]]
		+	[[Category: Drennan, C L]]
		+	[[Category: Funk, M A]]
		+	[[Category: Zimanyi, C M]]
		+	[[Category: Allostery]]
		+	[[Category: Nucleotide metabolism]]
		+	[[Category: Oxidoreductase]]
		+	[[Category: Ribonucleotide reductase]]
		+	[[Category: Substrate specificity]]

OCA at 11:34, 7 October 2015

2015-10-07T11:34:37Z

←Older revision		Revision as of 11:34, 7 October 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5cnt is ON HOLD	+	The entry 5cnt is ON HOLD until Paper Publication

	Authors: Chen, P.Y.-T., Zimanyi, C.M., Funk, M.A., Drennan, C.L.		Authors: Chen, P.Y.-T., Zimanyi, C.M., Funk, M.A., Drennan, C.L.

OCA at 12:16, 30 September 2015

2015-09-30T12:16:57Z

←Older revision		Revision as of 12:16, 30 September 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5cnt is ON HOLD ~~until Paper Publication~~	+	The entry 5cnt is ON HOLD

-	Authors: Chen, P.Y.-T., Zimanyi, C.M., Drennan, C.L.	+	Authors: Chen, P.Y.-T., Zimanyi, C.M., Funk, M.A., Drennan, C.L.

	Description: Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution		Description: Crystal structure of the dATP inhibited E. coli class Ia ribonucleotide reductase complex bound to UDP and dATP at 3.25 Angstroms resolution
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
		+	[[Category: Funk, M.A]]
	[[Category: Drennan, C.L]]		[[Category: Drennan, C.L]]
	[[Category: Chen, P.Y.-T]]		[[Category: Chen, P.Y.-T]]
	[[Category: Zimanyi, C.M]]		[[Category: Zimanyi, C.M]]

OCA at 13:18, 12 August 2015

2015-08-12T13:18:51Z

←Older revision		Revision as of 13:18, 12 August 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5cnt is ON HOLD	+	The entry 5cnt is ON HOLD until Paper Publication

	Authors: Chen, P.Y.-T., Zimanyi, C.M., Drennan, C.L.		Authors: Chen, P.Y.-T., Zimanyi, C.M., Drennan, C.L.

OCA: Protected "5cnt" [edit=sysop:move=sysop]

2015-07-29T13:37:08Z

Protected "5cnt" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:37, 29 July 2015