5cry - Revision history

OCA at 16:11, 8 November 2023

2023-11-08T16:11:31Z

←Older revision		Revision as of 16:11, 8 November 2023
Line 4:		Line 4:
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CRY FirstGlance]. <br>		<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CRY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.79Å</td></tr>
		+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [https://pdbe.org/5cry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [https://www.ebi.ac.uk/pdbsum/5cry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cry ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [https://pdbe.org/5cry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [https://www.ebi.ac.uk/pdbsum/5cry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cry ProSAT]</span></td></tr>
	</table>		</table>

OCA at 12:25, 14 June 2023

2023-06-14T12:25:29Z

←Older revision		Revision as of 12:25, 14 June 2023
Line 3:		Line 3:
	<StructureSection load='5cry' size='340' side='right'caption='[[5cry]], [[Resolution\|resolution]] 2.79Å' scene=''>		<StructureSection load='5cry' size='340' side='right'caption='[[5cry]], [[Resolution\|resolution]] 2.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5CRY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5CRY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>~~</td></tr>~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-	~~<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4oqo\|4oqo]]~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [https://pdbe.org/5cry PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [https://www.ebi.ac.uk/pdbsum/5cry PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5cry ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [~~http~~://pdbe.org/5cry PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5cry PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5cry ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>	+	[https://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>
		+
		+	==See Also==
		+	*[[Lactoferrin\|Lactoferrin]]
	== References ==		== References ==
	<references/>		<references/>
Line 16:		Line 18:
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Kaur, P]]	+	[[Category: Kaur P]]
-	[[Category: Rastogi, N]]	+	[[Category: Rastogi N]]
-	[[Category: Sharma, S]]	+	[[Category: Sharma S]]
-	[[Category: Singh, A]]	+	[[Category: Singh A]]
-	[[Category: Singh~~, P K~~]]	+	[[Category: Singh PK]]
-	[[Category: Singh~~, T P~~]]	+	[[Category: Singh TP]]
-	[[Category: Tyagi~~, T K]]~~	+	[[Category: Tyagi TK]]
-	~~[[Category: C-lobe]]~~	+
-	~~[[Category: Hydrolase~~]]	+

OCA at 10:21, 1 April 2020

2020-04-01T10:21:03Z

←Older revision		Revision as of 10:21, 1 April 2020
Line 1:		Line 1:
		+
	==Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination==		==Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination==
-	<StructureSection load='5cry' size='340' side='right' caption='[[5cry]], [[Resolution\|resolution]] 2.79Å' scene=''>	+	<StructureSection load='5cry' size='340' side='right'caption='[[5cry]], [[Resolution\|resolution]] 2.79Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CRY FirstGlance]. <br>		<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CRY FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4oqo\|4oqo]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4oqo\|4oqo]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [http://pdbe.org/5cry PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [http://www.ebi.ac.uk/pdbsum/5cry PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [http://pdbe.org/5cry PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [http://www.ebi.ac.uk/pdbsum/5cry PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5cry ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 14:		Line 15:
	</StructureSection>		</StructureSection>
	[[Category: Bos taurus]]		[[Category: Bos taurus]]
		+	[[Category: Large Structures]]
	[[Category: Kaur, P]]		[[Category: Kaur, P]]
	[[Category: Rastogi, N]]		[[Category: Rastogi, N]]

OCA at 04:08, 16 October 2015

2015-10-16T04:08:18Z

←Older revision		Revision as of 04:08, 16 October 2015
Line 1:		Line 1:
-	'''~~Unreleased structure~~'''	+	==Structure of iron-saturated C-lobe of bovine lactoferrin at pH 6.8 indicates the softening of iron coordination==
-		+	<StructureSection load='5cry' size='340' side='right' caption='[[5cry]], [[Resolution\|resolution]] 2.79Å' scene=''>
-	~~The entry~~ 5cry is ~~ON HOLD until Paper Publication~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5cry]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5CRY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5CRY FirstGlance]. <br>
-	~~Authors~~: ~~Singh~~, A., ~~Rastogi~~, N.~~, Singh, P~~.K., ~~Tyagi, T~~.K., ~~Kaur, P~~., ~~Sharma, S~~., ~~Singh, T~~.P.	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BCT:BICARBONATE+ION'>BCT</scene>, <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[4oqo\|4oqo]]</td></tr>
-	~~Description~~: ~~Structure of~~ iron-~~saturated C~~-~~lobe~~ of ~~bovine lactoferrin at pH 7~~.~~0 indicates~~ the ~~softening of iron coordination~~	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5cry FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5cry OCA], [http://pdbe.org/5cry PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5cry RCSB], [http://www.ebi.ac.uk/pdbsum/5cry PDBsum]</span></td></tr>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</table>
-	[[Category: ~~Singh, P.K~~]]	+	== Function ==
-	[[Category: ~~Singh~~, T.P]]	+	[[http://www.uniprot.org/uniprot/TRFL_BOVIN TRFL_BOVIN]] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactotransferrin has antimicrobial activity. The most effective inhibitory activity was seen against E.coli and P.aeruginosa.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> Lactoferricin B is an antimicrobial peptide. Inhibits the growth of Gram-negative and Gram-positive bacteria.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref> The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.<ref>PMID:8980754</ref> <ref>PMID:15222473</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bos taurus]]
		+	[[Category: Kaur, P]]
	[[Category: Rastogi, N]]		[[Category: Rastogi, N]]
-	[[Category: Singh, A]]
-	[[Category: Tyagi, T.K]]
	[[Category: Sharma, S]]		[[Category: Sharma, S]]
-	[[Category: ~~Kaur~~, P]]	+	[[Category: Singh, A]]
		+	[[Category: Singh, P K]]
		+	[[Category: Singh, T P]]
		+	[[Category: Tyagi, T K]]
		+	[[Category: C-lobe]]
		+	[[Category: Hydrolase]]

OCA at 11:39, 7 October 2015

2015-10-07T11:39:16Z

←Older revision		Revision as of 11:39, 7 October 2015
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5cry is ON HOLD	+	The entry 5cry is ON HOLD until Paper Publication

	Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K., Kaur, P., Sharma, S., Singh, T.P.		Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K., Kaur, P., Sharma, S., Singh, T.P.

OCA at 18:52, 5 August 2015

2015-08-05T18:52:38Z

←Older revision		Revision as of 18:52, 5 August 2015
Line 3:		Line 3:
	The entry 5cry is ON HOLD		The entry 5cry is ON HOLD

-	Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K, Kaur, P., Sharma, S., Singh, T.P.	+	Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K., Kaur, P., Sharma, S., Singh, T.P.

	Description: Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination		Description: Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Tyagi, T.K, Kaur, P]]
	[[Category: Singh, P.K]]		[[Category: Singh, P.K]]
	[[Category: Singh, T.P]]		[[Category: Singh, T.P]]
	[[Category: Rastogi, N]]		[[Category: Rastogi, N]]
	[[Category: Singh, A]]		[[Category: Singh, A]]
		+	[[Category: Tyagi, T.K]]
	[[Category: Sharma, S]]		[[Category: Sharma, S]]
		+	[[Category: Kaur, P]]

OCA: Protected "5cry" [edit=sysop:move=sysop]

2015-07-29T13:48:42Z

Protected "5cry" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:48, 29 July 2015

OCA: New page: '''Unreleased structure''' The entry 5cry is ON HOLD Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K, Kaur, P., Sharma, S., Singh, T.P. Description: Structure of iron-saturate...

2015-07-29T13:48:41Z

New page: '''Unreleased structure''' The entry 5cry is ON HOLD Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K, Kaur, P., Sharma, S., Singh, T.P. Description: Structure of iron-saturate...

New page

'''Unreleased structure'''

The entry 5cry is ON HOLD

Authors: Singh, A., Rastogi, N., Singh, P.K., Tyagi, T.K, Kaur, P., Sharma, S., Singh, T.P.

Description: Structure of iron-saturated C-lobe of bovine lactoferrin at pH 7.0 indicates the softening of iron coordination
[[Category: Unreleased Structures]]
[[Category: Tyagi, T.K, Kaur, P]]
[[Category: Singh, P.K]]
[[Category: Singh, T.P]]
[[Category: Rastogi, N]]
[[Category: Singh, A]]
[[Category: Sharma, S]]