5ds2 - Revision history

OCA at 21:57, 28 June 2023

2023-06-28T21:57:16Z

←Older revision		Revision as of 21:57, 28 June 2023
Line 3:		Line 3:
	<StructureSection load='5ds2' size='340' side='right'caption='[[5ds2]], [[Resolution\|resolution]] 1.85Å' scene=''>		<StructureSection load='5ds2' size='340' side='right'caption='[[5ds2]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ds2]] is a 6 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Garden_pea Garden pea~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DS2 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5DS2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ds2]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pisum_sativum Pisum sativum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DS2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DS2 FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name~~=~~'pdbligand=SO4:SULFATE+ION'>SO4</scene~~></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.85Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~HSP18.1 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3888 Garden pea])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ds2 OCA], [~~http~~://pdbe.org/5ds2 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5ds2 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5ds2 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5ds2 ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ds2 OCA], [https://pdbe.org/5ds2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ds2 RCSB], [https://www.ebi.ac.uk/pdbsum/5ds2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ds2 ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HSP11_PEA HSP11_PEA]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 24:		Line 26:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Garden pea]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Allison, T M~~]]	+	[[Category: Pisum sativum]]
-	[[Category: ~~Benesch, J L.P~~]]	+	[[Category: Allison TM]]
-	[[Category: ~~Hochberg, G K.A~~]]	+	[[Category: Benesch JLP]]
-	[[Category: ~~Laganowsky, A~~]]	+	[[Category: Hochberg GKA]]
-	[[Category: ~~Shepherd, D~~ A]]	+	[[Category: Laganowsky A]]
-	[[Category: ~~Chaperone]]~~	+	[[Category: Shepherd DA]]
-	~~[[Category: Small heat-shock protein]]~~	+
-	~~[[Category: Stress~~]]	+

OCA at 07:03, 4 March 2020

2020-03-04T07:03:24Z

←Older revision		Revision as of 07:03, 4 March 2020
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	==Core domain of the class I small heat-shock protein HSP 18.1 from Pisum sativum==		==Core domain of the class I small heat-shock protein HSP 18.1 from Pisum sativum==
-	<StructureSection load='5ds2' size='340' side='right' caption='[[5ds2]], [[Resolution\|resolution]] 1.85Å' scene=''>	+	<StructureSection load='5ds2' size='340' side='right'caption='[[5ds2]], [[Resolution\|resolution]] 1.85Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5ds2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DS2 FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5ds2]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Garden_pea Garden pea]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DS2 FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">HSP18.1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=3888 Garden pea])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ds2 OCA], [http://pdbe.org/5ds2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ds2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ds2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ds2 ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ds2 OCA], [http://pdbe.org/5ds2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ds2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ds2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ds2 ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Oligomeric proteins assemble with exceptional selectivity, even in the presence of closely related proteins, to perform their cellular roles. We show that most proteins related by gene duplication of an oligomeric ancestor have evolved to avoid hetero-oligomerization and that this correlates with their acquisition of distinct functions. We report how coassembly is avoided by two oligomeric small heat-shock protein paralogs. A hierarchy of assembly, involving intermediates that are populated only fleetingly at equilibrium, ensures selective oligomerization. Conformational flexibility at noninterfacial regions in the monomers prevents coassembly, allowing interfaces to remain largely conserved. Homomeric oligomers must overcome the entropic benefit of coassembly and, accordingly, homomeric paralogs comprise fewer subunits than homomers that have no paralogs.
		+
		+	Structural principles that enable oligomeric small heat-shock protein paralogs to evolve distinct functions.,Hochberg GKA, Shepherd DA, Marklund EG, Santhanagoplan I, Degiacomi MT, Laganowsky A, Allison TM, Basha E, Marty MT, Galpin MR, Struwe WB, Baldwin AJ, Vierling E, Benesch JLP Science. 2018 Feb 23;359(6378):930-935. doi: 10.1126/science.aam7229. PMID:29472485<ref>PMID:29472485</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5ds2" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Heat Shock Protein structures\|Heat Shock Protein structures]]
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Garden pea]]
		+	[[Category: Large Structures]]
	[[Category: Allison, T M]]		[[Category: Allison, T M]]
	[[Category: Benesch, J L.P]]		[[Category: Benesch, J L.P]]

OCA at 17:05, 3 October 2016

2016-10-03T17:05:06Z

←Older revision		Revision as of 17:05, 3 October 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5ds2 is ~~ON HOLD until Paper Publication~~	+	==Core domain of the class I small heat-shock protein HSP 18.1 from Pisum sativum==
-		+	<StructureSection load='5ds2' size='340' side='right' caption='[[5ds2]], [[Resolution\|resolution]] 1.85Å' scene=''>
-	~~Authors~~: ~~Shepherd, D~~.S.~~, Laganowsky, A~~., ~~Allison, T~~.M., ~~Hochberg~~, G.K.A., ~~Benesch, J~~.L.P.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5ds2]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DS2 FirstGlance]. <br>
-	~~Description~~: ~~Core domain of the class I small heat~~-~~shock protein HSP 18~~.~~1 from Pisum sativum~~	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ds2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ds2 OCA], [http://pdbe.org/5ds2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ds2 RCSB], [http://www.ebi.ac.uk/pdbsum/5ds2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ds2 ProSAT]</span></td></tr>
-	[[Category: ~~Allison~~, T.M]]	+	</table>
-	[[Category: ~~Shepherd~~, D.S]]	+	__TOC__
		+	</StructureSection>
		+	[[Category: Allison, T M]]
		+	[[Category: Benesch, J L.P]]
		+	[[Category: Hochberg, G K.A]]
	[[Category: Laganowsky, A]]		[[Category: Laganowsky, A]]
-	[[Category: ~~Hochberg~~, ~~G.K.~~A]]	+	[[Category: Shepherd, D A]]
-	[[Category: ~~Benesch, J.L.P~~]]	+	[[Category: Chaperone]]
		+	[[Category: Small heat-shock protein]]
		+	[[Category: Stress]]

OCA at 09:46, 10 August 2016

2016-08-10T09:46:49Z

←Older revision		Revision as of 09:46, 10 August 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5ds2 is ON HOLD	+	The entry 5ds2 is ON HOLD until Paper Publication

	Authors: Shepherd, D.S., Laganowsky, A., Allison, T.M., Hochberg, G.K.A., Benesch, J.L.P.		Authors: Shepherd, D.S., Laganowsky, A., Allison, T.M., Hochberg, G.K.A., Benesch, J.L.P.

OCA at 11:22, 16 December 2015

2015-12-16T11:22:36Z

←Older revision		Revision as of 11:22, 16 December 2015
Line 9:		Line 9:
	[[Category: Allison, T.M]]		[[Category: Allison, T.M]]
	[[Category: Shepherd, D.S]]		[[Category: Shepherd, D.S]]
-	[[Category: Benesch, J.L.P]]
	[[Category: Laganowsky, A]]		[[Category: Laganowsky, A]]
	[[Category: Hochberg, G.K.A]]		[[Category: Hochberg, G.K.A]]
		+	[[Category: Benesch, J.L.P]]

OCA: Protected "5ds2" [edit=sysop:move=sysop]

2015-09-30T13:26:38Z

Protected "5ds2" [edit=sysop:move=sysop]

←Older revision

Revision as of 13:26, 30 September 2015

OCA: New page: '''Unreleased structure''' The entry 5ds2 is ON HOLD Authors: Shepherd, D.S., Laganowsky, A., Allison, T.M., Hochberg, G.K.A., Benesch, J.L.P. Description: Core domain of the class I s...

2015-09-30T13:26:37Z

New page: '''Unreleased structure''' The entry 5ds2 is ON HOLD Authors: Shepherd, D.S., Laganowsky, A., Allison, T.M., Hochberg, G.K.A., Benesch, J.L.P. Description: Core domain of the class I s...

New page

'''Unreleased structure'''

The entry 5ds2 is ON HOLD

Authors: Shepherd, D.S., Laganowsky, A., Allison, T.M., Hochberg, G.K.A., Benesch, J.L.P.

Description: Core domain of the class I small heat-shock protein HSP 18.1 from Pisum sativum
[[Category: Unreleased Structures]]
[[Category: Allison, T.M]]
[[Category: Shepherd, D.S]]
[[Category: Benesch, J.L.P]]
[[Category: Laganowsky, A]]
[[Category: Hochberg, G.K.A]]