5eha - Revision history

OCA at 06:27, 5 July 2023

2023-07-05T06:27:12Z

←Older revision		Revision as of 06:27, 5 July 2023
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	<StructureSection load='5eha' size='340' side='right'caption='[[5eha]], [[Resolution\|resolution]] 1.35Å' scene=''>		<StructureSection load='5eha' size='340' side='right'caption='[[5eha]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5eha]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Agabi Agabi~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EHA OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5EHA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5eha]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Agaricus_bisporus Agaricus bisporus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EHA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EHA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5eha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eha OCA], [~~http~~://pdbe.org/5eha PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5eha RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5eha PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5eha ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.35Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eha OCA], [https://pdbe.org/5eha PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eha RCSB], [https://www.ebi.ac.uk/pdbsum/5eha PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eha ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/G1K3P4_AGABI G1K3P4_AGABI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Agabi~~]]	+	[[Category: Agaricus bisporus]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Dijkstra~~, B W~~]]	+	[[Category: Dijkstra BW]]
-	[[Category: Lai, X L]]	+	[[Category: Lai X-L]]
-	[[Category: Soler-Lopez, M]]	+	[[Category: Soler-Lopez M]]
-	[[Category: Wichers~~, H J]]~~	+	[[Category: Wichers HJ]]
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Lectin]]~~	+
-	~~[[Category: Tyrosinase~~]]	+

OCA at 06:58, 22 April 2020

2020-04-22T06:58:05Z

←Older revision		Revision as of 06:58, 22 April 2020
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	==Crystal structure of recombinant MtaL at 1.35 Angstrom resolution==		==Crystal structure of recombinant MtaL at 1.35 Angstrom resolution==
-	<StructureSection load='5eha' size='340' side='right' caption='[[5eha]], [[Resolution\|resolution]] 1.35Å' scene=''>	+	<StructureSection load='5eha' size='340' side='right'caption='[[5eha]], [[Resolution\|resolution]] 1.35Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5eha]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EHA OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5EHA FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5eha]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Agabi Agabi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EHA OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EHA FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5eha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eha OCA], [http://pdbe.org/5eha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eha RCSB], [http://www.ebi.ac.uk/pdbsum/5eha PDBsum]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5eha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eha OCA], [http://pdbe.org/5eha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eha RCSB], [http://www.ebi.ac.uk/pdbsum/5eha PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eha ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Agabi]]
		+	[[Category: Large Structures]]
	[[Category: Dijkstra, B W]]		[[Category: Dijkstra, B W]]
	[[Category: Lai, X L]]		[[Category: Lai, X L]]

OCA at 03:37, 10 March 2016

2016-03-10T03:37:23Z

←Older revision		Revision as of 03:37, 10 March 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5eha is ~~ON HOLD~~	+	==Crystal structure of recombinant MtaL at 1.35 Angstrom resolution==
		+	<StructureSection load='5eha' size='340' side='right' caption='[[5eha]], [[Resolution\|resolution]] 1.35Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5eha]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EHA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EHA FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eha FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eha OCA], [http://pdbe.org/5eha PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eha RCSB], [http://www.ebi.ac.uk/pdbsum/5eha PDBsum]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Mushroom tyrosinase-associated lectin-like protein (MtaL) binds to mature Agaricus bisporus tyrosinase in vivo, but the exact physiological function of MtaL is unknown. In this study, the crystal structure of recombinant MtaL is reported at 1.35 A resolution. Comparison of its structure with that of the truncated and cleaved MtaL present in the complex with tyrosinase directly isolated from mushroom shows that the general beta-trefoil fold is conserved. However, differences are detected in the loop regions, particularly in the beta2-beta3 loop, which is intact and not cleaved in the recombinant MtaL. Furthermore, the N-terminal tail is rotated inwards, covering the tyrosinase-binding interface. Thus, MtaL must undergo conformational changes in order to bind mature mushroom tyrosinase. Very interestingly, the beta-trefoil fold has been identified to be essential for carbohydrate interaction in other lectin-like proteins. Comparison of the structures of MtaL and a ricin-B-like lectin with a bound disaccharide shows that MtaL may have a similar carbohydrate-binding site that might be involved in glycoreceptor activity.

-	~~Authors: Lai, X.~~-L., Soler-Lopez, M., Wichers, H.J., ~~Dijkstra, B~~.W.	+	Crystal structure of recombinant tyrosinase-binding protein MtaL at 1.35 A resolution.,Lai X, Soler-Lopez M, Ismaya WT, Wichers HJ, Dijkstra BW Acta Crystallogr F Struct Biol Commun. 2016 Mar 1;72(Pt 3):244-50. doi:, 10.1107/S2053230X16002107. Epub 2016 Feb 19. PMID:26919530<ref>PMID:26919530</ref>

-	~~Description: Crystal structure~~ of ~~recombinant MtaL at 1~~.~~35 Angstrom resolution~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
-	[[Category: Dijkstra, B.W]]	+	<div class="pdbe-citations 5eha" style="background-color:#fffaf0;"></div>
-	[[Category: Lai, X.-L]]	+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Dijkstra, B W]]
		+	[[Category: Lai, X L]]
	[[Category: Soler-Lopez, M]]		[[Category: Soler-Lopez, M]]
-	[[Category: Wichers, H.J]]	+	[[Category: Wichers, H J]]
		+	[[Category: Hydrolase]]
		+	[[Category: Lectin]]
		+	[[Category: Tyrosinase]]

OCA: Protected "5eha" [edit=sysop:move=sysop]

2015-12-01T02:50:19Z

Protected "5eha" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:50, 1 December 2015

OCA: New page: '''Unreleased structure''' The entry 5eha is ON HOLD Authors: Lai, X.-L., Soler-Lopez, M., Wichers, H.J., Dijkstra, B.W. Description: Crystal structure of recombinant MtaL at 1.35 Angs...

2015-12-01T02:50:18Z

New page: '''Unreleased structure''' The entry 5eha is ON HOLD Authors: Lai, X.-L., Soler-Lopez, M., Wichers, H.J., Dijkstra, B.W. Description: Crystal structure of recombinant MtaL at 1.35 Angs...

New page

'''Unreleased structure'''

The entry 5eha is ON HOLD

Authors: Lai, X.-L., Soler-Lopez, M., Wichers, H.J., Dijkstra, B.W.

Description: Crystal structure of recombinant MtaL at 1.35 Angstrom resolution
[[Category: Unreleased Structures]]
[[Category: Dijkstra, B.W]]
[[Category: Lai, X.-L]]
[[Category: Soler-Lopez, M]]
[[Category: Wichers, H.J]]