5f2q - Revision history

OCA at 08:43, 12 July 2023

2023-07-12T08:43:09Z

←Older revision		Revision as of 08:43, 12 July 2023
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	<StructureSection load='5f2q' size='340' side='right'caption='[[5f2q]], [[Resolution\|resolution]] 2.95Å' scene=''>		<StructureSection load='5f2q' size='340' side='right'caption='[[5f2q]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5f2q]] is a 10 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2Q OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5F2Q FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5f2q]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F2Q FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.95Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5f2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f2q OCA], [~~http~~://pdbe.org/5f2q PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5f2q RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5f2q PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5f2q ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f2q OCA], [https://pdbe.org/5f2q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f2q RCSB], [https://www.ebi.ac.uk/pdbsum/5f2q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f2q ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/LECG_BOTJR LECG_BOTJR]] Galactose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids. Calcium-dependent lectin. Shows high hemagglutinating activity. When injected into mouse hind paws, (10-100 ug/paw) causes edema and increases vascular permeability. In anesthetized rats, decreases the blood pressure by approximately 15%, with a rapid return to the resting level (PubMed:16309723). Is an effective inhibitor of cell growth in some cancer cell lines, especially against renal and pancreatic cancer cell lines, human breast and ovarian carcinoma, glioblastoma and a bovine brain microvascular endothelial cell line (PubMed:10628348, PubMed:11478954).<ref>PMID:10628348</ref> <ref>PMID:11478954</ref> <ref>PMID:16309723</ref> <ref>PMID:11902666</ref>	+	[https://www.uniprot.org/uniprot/LECG_BOTJR LECG_BOTJR] Galactose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids. Calcium-dependent lectin. Shows high hemagglutinating activity. When injected into mouse hind paws, (10-100 ug/paw) causes edema and increases vascular permeability. In anesthetized rats, decreases the blood pressure by approximately 15%, with a rapid return to the resting level (PubMed:16309723). Is an effective inhibitor of cell growth in some cancer cell lines, especially against renal and pancreatic cancer cell lines, human breast and ovarian carcinoma, glioblastoma and a bovine brain microvascular endothelial cell line (PubMed:10628348, PubMed:11478954).<ref>PMID:10628348</ref> <ref>PMID:11478954</ref> <ref>PMID:16309723</ref> <ref>PMID:11902666</ref>
	== References ==		== References ==
	<references/>		<references/>
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	[[Category: Bothrops jararacussu]]		[[Category: Bothrops jararacussu]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Nonato~~, M C]]~~	+	[[Category: Nonato MC]]
-	~~[[Category: Padua, R A.P de~~]]	+	[[Category: Pinheiro MP]]
-	[[Category: Pinheiro~~, M P~~]]	+	[[Category: Sampaio SV]]
-	[[Category: Sampaio~~, S V~~]]	+	[[Category: Sartim MA]]
-	[[Category: Sartim~~, M A~~]]	+	[[Category: De Padua RAP]]
-	[[Category: ~~C-type lectin]]~~	+
-	~~[[Category: Calcium]]~~	+
-	~~[[Category: Decamer]]~~	+
-	~~[[Category: Sugar binding protein~~]]	+

OCA at 06:21, 17 April 2019

2019-04-17T06:21:36Z

←Older revision		Revision as of 06:21, 17 April 2019
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	==C-type lectin from Bothrops jararacussu==		==C-type lectin from Bothrops jararacussu==
-	<StructureSection load='5f2q' size='340' side='right' caption='[[5f2q]], [[Resolution\|resolution]] 2.95Å' scene=''>	+	<StructureSection load='5f2q' size='340' side='right'caption='[[5f2q]], [[Resolution\|resolution]] 2.95Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5f2q]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F2Q FirstGlance]. <br>		<table><tr><td colspan='2'>[[5f2q]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F2Q FirstGlance]. <br>
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	</StructureSection>		</StructureSection>
	[[Category: Bothrops jararacussu]]		[[Category: Bothrops jararacussu]]
		+	[[Category: Large Structures]]
	[[Category: Nonato, M C]]		[[Category: Nonato, M C]]
	[[Category: Padua, R A.P de]]		[[Category: Padua, R A.P de]]

OCA at 02:09, 11 December 2016

2016-12-11T02:09:54Z

←Older revision		Revision as of 02:09, 11 December 2016
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-	'''Unreleased structure'''

-	~~The entry~~ 5f2q ~~is ON HOLD until Paper Publication~~	+	==C-type lectin from Bothrops jararacussu==
-		+	<StructureSection load='5f2q' size='340' side='right' caption='[[5f2q]], [[Resolution\|resolution]] 2.95Å' scene=''>
-	~~Authors~~: ~~de Padua~~, R.A.P., ~~Pinheiro, M~~.P., ~~Sartim~~, M.A., ~~Sampaio, S~~.V., ~~Nonato, M~~.C.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5f2q]] is a 10 chain structure with sequence from [http://en.wikipedia.org/wiki/Bothrops_jararacussu Bothrops jararacussu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F2Q OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5F2Q FirstGlance]. <br>
-	~~Description~~: C-~~type~~ lectin ~~from~~ Bothrops jararacussu	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5f2q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f2q OCA], [http://pdbe.org/5f2q PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5f2q RCSB], [http://www.ebi.ac.uk/pdbsum/5f2q PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5f2q ProSAT]</span></td></tr>
-	[[Category: ~~Sartim~~, M.A]]	+	</table>
-	[[Category: ~~Nonato~~, M.C]]	+	== Function ==
-	[[Category: Sampaio, S.V]]	+	[[http://www.uniprot.org/uniprot/LECG_BOTJR LECG_BOTJR]] Galactose-binding lectin which recognizes specific carbohydrate structures and agglutinates a variety of animal cells by binding to cell-surface glycoproteins and glycolipids. Calcium-dependent lectin. Shows high hemagglutinating activity. When injected into mouse hind paws, (10-100 ug/paw) causes edema and increases vascular permeability. In anesthetized rats, decreases the blood pressure by approximately 15%, with a rapid return to the resting level (PubMed:16309723). Is an effective inhibitor of cell growth in some cancer cell lines, especially against renal and pancreatic cancer cell lines, human breast and ovarian carcinoma, glioblastoma and a bovine brain microvascular endothelial cell line (PubMed:10628348, PubMed:11478954).<ref>PMID:10628348</ref> <ref>PMID:11478954</ref> <ref>PMID:16309723</ref> <ref>PMID:11902666</ref>
-	[[Category: ~~De Padua~~, R.A.P]]	+	== References ==
-	[[Category: ~~Pinheiro, M.P~~]]	+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Bothrops jararacussu]]
		+	[[Category: Nonato, M C]]
		+	[[Category: Padua, R A.P de]]
		+	[[Category: Pinheiro, M P]]
		+	[[Category: Sampaio, S V]]
		+	[[Category: Sartim, M A]]
		+	[[Category: C-type lectin]]
		+	[[Category: Calcium]]
		+	[[Category: Decamer]]
		+	[[Category: Sugar binding protein]]

OCA at 22:40, 10 May 2016

2016-05-10T22:40:21Z

←Older revision		Revision as of 22:40, 10 May 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5f2q is ON HOLD	+	The entry 5f2q is ON HOLD until Paper Publication

	Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Sampaio, S.V., Nonato, M.C.		Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Sampaio, S.V., Nonato, M.C.

OCA at 14:48, 26 February 2016

2016-02-26T14:48:36Z

←Older revision		Revision as of 14:48, 26 February 2016
Line 3:		Line 3:
	The entry 5f2q is ON HOLD		The entry 5f2q is ON HOLD

-	Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., ~~Vilela~~, S.S., Nonato, M.C.	+	Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Sampaio, S.V., Nonato, M.C.

	Description: C-type lectin from Bothrops jararacussu		Description: C-type lectin from Bothrops jararacussu
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	[[Category: Sartim, M.A]]		[[Category: Sartim, M.A]]
	[[Category: Nonato, M.C]]		[[Category: Nonato, M.C]]
		+	[[Category: Sampaio, S.V]]
	[[Category: De Padua, R.A.P]]		[[Category: De Padua, R.A.P]]
-	[[Category: Vilela, S.S]]
	[[Category: Pinheiro, M.P]]		[[Category: Pinheiro, M.P]]

OCA: Protected "5f2q" [edit=sysop:move=sysop]

2015-12-09T12:32:32Z

Protected "5f2q" [edit=sysop:move=sysop]

←Older revision

Revision as of 12:32, 9 December 2015

OCA: New page: '''Unreleased structure''' The entry 5f2q is ON HOLD Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Vilela, S.S., Nonato, M.C. Description: C-type lectin from Bothrops jarara...

2015-12-09T12:32:30Z

New page: '''Unreleased structure''' The entry 5f2q is ON HOLD Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Vilela, S.S., Nonato, M.C. Description: C-type lectin from Bothrops jarara...

New page

'''Unreleased structure'''

The entry 5f2q is ON HOLD

Authors: de Padua, R.A.P., Pinheiro, M.P., Sartim, M.A., Vilela, S.S., Nonato, M.C.

Description: C-type lectin from Bothrops jararacussu
[[Category: Unreleased Structures]]
[[Category: Sartim, M.A]]
[[Category: Nonato, M.C]]
[[Category: De Padua, R.A.P]]
[[Category: Vilela, S.S]]
[[Category: Pinheiro, M.P]]