5fmv - Revision history

OCA at 07:22, 1 May 2024

2024-05-01T07:22:48Z

←Older revision		Revision as of 07:22, 1 May 2024
Line 12:		Line 12:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN] Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).		[https://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN] Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	It has been proposed that the local segregation of kinases and the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such segregation occurs and whether it can initiate signaling is unclear. Using structural and biophysical analysis, we show that the extracellular region of CD45 is rigid and extends beyond the distance spanned by TCR-ligand complexes, implying that sites of TCR-ligand engagement would sterically exclude CD45. We also show that the formation of 'close contacts', new structures characterized by spontaneous CD45 and kinase segregation at the submicron-scale, initiates signaling even when TCR ligands are absent. Our work reveals the structural basis for, and the potent signaling effects of, local CD45 and kinase segregation. TCR ligands have the potential to heighten signaling simply by holding receptors in close contacts.
-
-	Initiation of T cell signaling by CD45 segregation at 'close contacts'.,Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jonsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJ, Klenerman D, Aricescu AR, Davis SJ Nat Immunol. 2016 May;17(5):574-82. doi: 10.1038/ni.3392. Epub 2016 Mar 21. PMID:26998761<ref>PMID:26998761</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5fmv" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]		*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 06:58, 19 July 2023

2023-07-19T06:58:26Z

←Older revision		Revision as of 06:58, 19 July 2023
Line 3:		Line 3:
	<StructureSection load='5fmv' size='340' side='right'caption='[[5fmv]], [[Resolution\|resolution]] 2.90Å' scene=''>		<StructureSection load='5fmv' size='340' side='right'caption='[[5fmv]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FMV OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5FMV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fmv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FMV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FMV FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=NAG:N~~-~~ACETYL-D-GLUCOSAMINE'>NAG</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.9Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	~~<tr~~ id~~='activity'><td class~~="~~sblockLbl~~"><~~b>Activity~~:~~</b~~></td><~~td class~~=~~"sblockDat"><span class~~=~~'plainlinks~~'>~~[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48]~~ </~~span~~></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [https://pdbe.org/5fmv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [https://www.ebi.ac.uk/pdbsum/5fmv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fmv ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [~~http~~://pdbe.org/5fmv PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5fmv PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5fmv ProSAT]</span></td></tr>	+
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN]] T-B+ severe combined immunodeficiency due to CD45 deficiency. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility may be associated with variations affecting the gene represented in this entry.	+	[https://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN] T-B+ severe combined immunodeficiency due to CD45 deficiency. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility may be associated with variations affecting the gene represented in this entry.
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN]] Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).	+	[https://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN] Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 29:		Line 28:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	~~[[Category: Protein-tyrosine-phosphatase]]~~	+	[[Category: Aricescu AR]]
-	[[Category: Aricescu~~, A R~~]]	+	[[Category: Chang VT]]
-	[[Category: Chang~~, V T~~]]	+	[[Category: Coles CH]]
-	[[Category: Coles~~, C H~~]]	+	[[Category: Davis SJ]]
-	[[Category: Davis~~, S J~~]]	+	[[Category: Fernandes RA]]
-	[[Category: Fernandes~~, R A~~]]	+	[[Category: Ganzinger KA]]
-	[[Category: Ganzinger~~, K A~~]]	+	[[Category: Gilbert RJC]]
-	[[Category: Gilbert~~, R J.C~~]]	+	[[Category: Harlos K]]
-	[[Category: Harlos, K]]	+	[[Category: Huang E]]
-	[[Category: Huang, E]]	+	[[Category: Jones EY]]
-	[[Category: Jones~~, E Y~~]]	+	[[Category: Jonsson P]]
-	[[Category: Jonsson, P]]	+	[[Category: Klenerman D]]
-	[[Category: Klenerman, D]]	+	[[Category: Lee SF]]
-	[[Category: Lee~~, S F~~]]	+	[[Category: Lui Y]]
-	[[Category: Lui, Y]]	+	[[Category: McColl J]]
-	[[Category: McColl, J]]	+	[[Category: Palayret M]]
-	[[Category: Palayret, M]]	+	[[Category: Siebold C]]
-	[[Category: Siebold, C]]	+
-	~~[[Category: Cd45]]~~	+
-	~~[[Category: Hydrolase]]~~	+
-	~~[[Category: Ptprc]]~~	+
-	~~[[Category: Receptor protein tyrosine phosphatase~~]]	+

OCA at 07:26, 6 May 2020

2020-05-06T07:26:30Z

←Older revision		Revision as of 07:26, 6 May 2020
Line 1:		Line 1:

	==Crystal structure of human CD45 extracellular region, domains d1-d4==		==Crystal structure of human CD45 extracellular region, domains d1-d4==
-	<StructureSection load='5fmv' size='340' side='right' caption='[[5fmv]], [[Resolution\|resolution]] 2.90Å' scene=''>	+	<StructureSection load='5fmv' size='340' side='right'caption='[[5fmv]], [[Resolution\|resolution]] 2.90Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5fmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FMV OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5FMV FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5fmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FMV OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5FMV FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [http://pdbe.org/5fmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [http://www.ebi.ac.uk/pdbsum/5fmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fmv ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [http://pdbe.org/5fmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [http://www.ebi.ac.uk/pdbsum/5fmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fmv ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 24:		Line 24:

	==See Also==		==See Also==
-	*[[Tyrosine phosphatase\|Tyrosine phosphatase]]	+	*[[Tyrosine phosphatase 3D structures\|Tyrosine phosphatase 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Protein-tyrosine-phosphatase]]		[[Category: Protein-tyrosine-phosphatase]]
	[[Category: Aricescu, A R]]		[[Category: Aricescu, A R]]

OCA at 10:49, 13 September 2017

2017-09-13T10:49:17Z

←Older revision		Revision as of 10:49, 13 September 2017
Line 7:		Line 7:
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>
	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>		<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [http://pdbe.org/5fmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [http://www.ebi.ac.uk/pdbsum/5fmv PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [http://pdbe.org/5fmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [http://www.ebi.ac.uk/pdbsum/5fmv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fmv ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 22:		Line 22:
	</div>		</div>
	<div class="pdbe-citations 5fmv" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5fmv" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Tyrosine phosphatase\|Tyrosine phosphatase]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:32, 10 May 2016

2016-05-10T16:32:30Z

←Older revision		Revision as of 16:32, 10 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	The entry ~~5fmv~~ is ~~ON HOLD~~	+	==Crystal structure of human CD45 extracellular region, domains d1-d4==
		+	<StructureSection load='5fmv' size='340' side='right' caption='[[5fmv]], [[Resolution\|resolution]] 2.90Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5fmv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FMV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FMV FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5fn6\|5fn6]], [[5fn7\|5fn7]], [[5fn8\|5fn8]]</td></tr>
		+	<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Protein-tyrosine-phosphatase Protein-tyrosine-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.48 3.1.3.48] </span></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fmv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fmv OCA], [http://pdbe.org/5fmv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fmv RCSB], [http://www.ebi.ac.uk/pdbsum/5fmv PDBsum]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN]] T-B+ severe combined immunodeficiency due to CD45 deficiency. The disease is caused by mutations affecting the gene represented in this entry. Disease susceptibility may be associated with variations affecting the gene represented in this entry.
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/PTPRC_HUMAN PTPRC_HUMAN]] Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity (By similarity).
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	It has been proposed that the local segregation of kinases and the tyrosine phosphatase CD45 underpins T cell antigen receptor (TCR) triggering, but how such segregation occurs and whether it can initiate signaling is unclear. Using structural and biophysical analysis, we show that the extracellular region of CD45 is rigid and extends beyond the distance spanned by TCR-ligand complexes, implying that sites of TCR-ligand engagement would sterically exclude CD45. We also show that the formation of 'close contacts', new structures characterized by spontaneous CD45 and kinase segregation at the submicron-scale, initiates signaling even when TCR ligands are absent. Our work reveals the structural basis for, and the potent signaling effects of, local CD45 and kinase segregation. TCR ligands have the potential to heighten signaling simply by holding receptors in close contacts.

-	~~Authors: Chang, V.~~T., Fernandes~~, R.A.~~, Ganzinger~~, K.A.~~, Lee~~, S.F.~~, Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles~~, C.H.~~, Jones~~, E.Y.~~, Lui, Y., Huang, E., Gilbert~~, R.J.C.~~, Klenerman, D., Aricescu, A.R.~~, Davis, S~~.J.	+	Initiation of T cell signaling by CD45 segregation at 'close contacts'.,Chang VT, Fernandes RA, Ganzinger KA, Lee SF, Siebold C, McColl J, Jonsson P, Palayret M, Harlos K, Coles CH, Jones EY, Lui Y, Huang E, Gilbert RJ, Klenerman D, Aricescu AR, Davis SJ Nat Immunol. 2016 May;17(5):574-82. doi: 10.1038/ni.3392. Epub 2016 Mar 21. PMID:26998761<ref>PMID:26998761</ref>

-	~~Description: Crystal structure of human CD45 extracellular region~~, ~~domains d1~~-d4	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
-	[[Category: ~~Huang~~, E]]	+	<div class="pdbe-citations 5fmv" style="background-color:#fffaf0;"></div>
-	[[Category: ~~Gilbert~~, ~~R.J.C~~]]	+	== References ==
-	[[Category: ~~Davis~~, ~~S.J~~]]	+	<references/>
-	[[Category: ~~Ganzinger~~, ~~K.A~~]]	+	__TOC__
-	[[Category: ~~Lee~~, ~~S.F~~]]	+	</StructureSection>
-	[[Category: ~~Aricescu~~, A.R]]	+	[[Category: Protein-tyrosine-phosphatase]]
-	[[Category: ~~Lui~~, Y]]	+	[[Category: Aricescu, A R]]
		+	[[Category: Chang, V T]]
		+	[[Category: Coles, C H]]
		+	[[Category: Davis, S J]]
		+	[[Category: Fernandes, R A]]
		+	[[Category: Ganzinger, K A]]
		+	[[Category: Gilbert, R J.C]]
	[[Category: Harlos, K]]		[[Category: Harlos, K]]
-	[[Category: ~~Coles~~, ~~C.H~~]]	+	[[Category: Huang, E]]
-	[[Category: Jones, E.Y]]	+	[[Category: Jones, E Y]]
-	[[Category: ~~Fernandes, R.A]]~~	+	[[Category: Jonsson, P]]
-	~~[[Category: Chang, V.T]]~~	+
-	~~[[Category: Mccoll~~, J]]	+
	[[Category: Klenerman, D]]		[[Category: Klenerman, D]]
		+	[[Category: Lee, S F]]
		+	[[Category: Lui, Y]]
		+	[[Category: McColl, J]]
	[[Category: Palayret, M]]		[[Category: Palayret, M]]
-	[[Category: Jonsson, P]]
	[[Category: Siebold, C]]		[[Category: Siebold, C]]
		+	[[Category: Cd45]]
		+	[[Category: Hydrolase]]
		+	[[Category: Ptprc]]
		+	[[Category: Receptor protein tyrosine phosphatase]]

OCA: Protected "5fmv" [edit=sysop:move=sysop]

2015-12-01T03:37:28Z

Protected "5fmv" [edit=sysop:move=sysop]

←Older revision

Revision as of 03:37, 1 December 2015

OCA: New page: '''Unreleased structure''' The entry 5fmv is ON HOLD Authors: Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., C...

2015-12-01T03:37:26Z

New page: '''Unreleased structure''' The entry 5fmv is ON HOLD Authors: Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., C...

New page

'''Unreleased structure'''

The entry 5fmv is ON HOLD

Authors: Chang, V.T., Fernandes, R.A., Ganzinger, K.A., Lee, S.F., Siebold, C., McColl, J., Jonsson, P., Palayret, M., Harlos, K., Coles, C.H., Jones, E.Y., Lui, Y., Huang, E., Gilbert, R.J.C., Klenerman, D., Aricescu, A.R., Davis, S.J.

Description: Crystal structure of human CD45 extracellular region, domains d1-d4
[[Category: Unreleased Structures]]
[[Category: Huang, E]]
[[Category: Gilbert, R.J.C]]
[[Category: Davis, S.J]]
[[Category: Ganzinger, K.A]]
[[Category: Lee, S.F]]
[[Category: Aricescu, A.R]]
[[Category: Lui, Y]]
[[Category: Harlos, K]]
[[Category: Coles, C.H]]
[[Category: Jones, E.Y]]
[[Category: Fernandes, R.A]]
[[Category: Chang, V.T]]
[[Category: Mccoll, J]]
[[Category: Klenerman, D]]
[[Category: Palayret, M]]
[[Category: Jonsson, P]]
[[Category: Siebold, C]]