5giy - Revision history

OCA at 11:32, 2 August 2023

2023-08-02T11:32:46Z

←Older revision		Revision as of 11:32, 2 August 2023
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	<StructureSection load='5giy' size='340' side='right'caption='[[5giy]], [[Resolution\|resolution]] 2.54Å' scene=''>		<StructureSection load='5giy' size='340' side='right'caption='[[5giy]], [[Resolution\|resolution]] 2.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5giy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIY OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5GIY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5giy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GIY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GE:pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)'>7GE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.543Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5giy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giy OCA], [~~http~~://pdbe.org/5giy PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5giy RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5giy PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5giy ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GE:pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)'>7GE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5giy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giy OCA], [https://pdbe.org/5giy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5giy RCSB], [https://www.ebi.ac.uk/pdbsum/5giy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5giy ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
-	[~~[http~~://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[~~http~~://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>	+	[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[https://omim.org/entry/103600 103600]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>	+	[https://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>

	==See Also==		==See Also==
Line 18:		Line 19:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Wang, T]]	+	[[Category: Wang T]]
-	[[Category: Yang, F]]	+	[[Category: Yang F]]
-	~~[[Category: Anticancer activity]]~~	+
-	~~[[Category: Drug delivery system]]~~	+
-	~~[[Category: Human serum albumin]]~~	+
-	~~[[Category: Interactions of protein-ligand]]~~	+
-	~~[[Category: Peptide binding protein]]~~	+
-	~~[[Category: Ruthenium-based drug~~]]	+

OCA at 06:44, 13 May 2020

2020-05-13T06:44:19Z

←Older revision		Revision as of 06:44, 13 May 2020
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	==HSA-Palmitic acid-[RuCl5(ind)]2-==		==HSA-Palmitic acid-[RuCl5(ind)]2-==
-	<StructureSection load='5giy' size='340' side='right' caption='[[5giy]], [[Resolution\|resolution]] 2.54Å' scene=''>	+	<StructureSection load='5giy' size='340' side='right'caption='[[5giy]], [[Resolution\|resolution]] 2.54Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5giy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIY OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5GIY FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5giy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5GIY FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7GE:pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)'>7GE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7GE:pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)'>7GE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5giy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giy OCA], [http://pdbe.org/5giy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giy RCSB], [http://www.ebi.ac.uk/pdbsum/5giy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giy ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5giy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giy OCA], [http://pdbe.org/5giy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giy RCSB], [http://www.ebi.ac.uk/pdbsum/5giy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giy ProSAT]</span></td></tr>
	</table>		</table>
	== Disease ==		== Disease ==
Line 11:		Line 11:
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>		[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
		+
		+	==See Also==
		+	*[[Albumin 3D structures\|Albumin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Wang, T]]		[[Category: Wang, T]]
	[[Category: Yang, F]]		[[Category: Yang, F]]

OCA at 15:58, 20 October 2017

2017-10-20T15:58:07Z

←Older revision		Revision as of 15:58, 20 October 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5giy is ~~ON HOLD until Jun 25 2018~~	+	==HSA-Palmitic acid-[RuCl5(ind)]2-==
-		+	<StructureSection load='5giy' size='340' side='right' caption='[[5giy]], [[Resolution\|resolution]] 2.54Å' scene=''>
-	~~Authors~~: ~~Yang~~, F., ~~Wang~~, T.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5giy]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GIY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GIY FirstGlance]. <br>
-	~~Description~~: ~~HSA-Palmitic acid-~~[~~RuCl5~~(~~ind~~)]2-	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7GE:pentakis(chloranyl)-(1~{H}-indazol-2-ium-2-yl)ruthenium(1-)'>7GE</scene>, <scene name='pdbligand=PLM:PALMITIC+ACID'>PLM</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5giy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5giy OCA], [http://pdbe.org/5giy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5giy RCSB], [http://www.ebi.ac.uk/pdbsum/5giy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5giy ProSAT]</span></td></tr>
		+	</table>
		+	== Disease ==
		+	[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Defects in ALB are a cause of familial dysalbuminemic hyperthyroxinemia (FDH) [MIM:[http://omim.org/entry/103600 103600]]. FDH is a form of euthyroid hyperthyroxinemia that is due to increased affinity of ALB for T(4). It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.<ref>PMID:8048949</ref> <ref>PMID:7852505</ref> <ref>PMID:9329347</ref> <ref>PMID:9589637</ref>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/ALBU_HUMAN ALBU_HUMAN]] Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.<ref>PMID:19021548</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Wang, T]]
	[[Category: Yang, F]]		[[Category: Yang, F]]
-	[[Category: ~~Wang, T~~]]	+	[[Category: Anticancer activity]]
		+	[[Category: Drug delivery system]]
		+	[[Category: Human serum albumin]]
		+	[[Category: Interactions of protein-ligand]]
		+	[[Category: Peptide binding protein]]
		+	[[Category: Ruthenium-based drug]]

OCA at 06:36, 10 May 2017

2017-05-10T06:36:44Z

←Older revision		Revision as of 06:36, 10 May 2017
Line 7:		Line 7:
	Description: HSA-Palmitic acid-[RuCl5(ind)]2-		Description: HSA-Palmitic acid-[RuCl5(ind)]2-
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Wang, T]]
	[[Category: Yang, F]]		[[Category: Yang, F]]
		+	[[Category: Wang, T]]

OCA at 13:10, 9 December 2016

2016-12-09T13:10:51Z

←Older revision		Revision as of 13:10, 9 December 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5giy is ON HOLD	+	The entry 5giy is ON HOLD until Jun 25 2018

	Authors: Yang, F., Wang, T.		Authors: Yang, F., Wang, T.

OCA at 12:37, 26 October 2016

2016-10-26T12:37:16Z

←Older revision		Revision as of 12:37, 26 October 2016
Line 3:		Line 3:
	The entry 5giy is ON HOLD		The entry 5giy is ON HOLD

-	Authors: ~~feng yang~~, ~~tao wang~~	+	Authors: Yang, F., Wang, T.

	Description: HSA-Palmitic acid-[RuCl5(ind)]2-		Description: HSA-Palmitic acid-[RuCl5(ind)]2-
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: ~~Feng~~ Yang, ~~Tao Wang~~]]	+	[[Category: Wang, T]]
		+	[[Category: Yang, F]]

OCA: Protected "5giy" [edit=sysop:move=sysop]

2016-07-12T21:37:39Z

Protected "5giy" [edit=sysop:move=sysop]

←Older revision

Revision as of 21:37, 12 July 2016

OCA: New page: '''Unreleased structure''' The entry 5giy is ON HOLD Authors: feng yang, tao wang Description: HSA-Palmitic acid-[RuCl5(ind)]2- Category: Unreleased Structures [[Category: Feng Yan...

2016-07-12T21:37:37Z

New page: '''Unreleased structure''' The entry 5giy is ON HOLD Authors: feng yang, tao wang Description: HSA-Palmitic acid-[RuCl5(ind)]2- Category: Unreleased Structures [[Category: Feng Yan...

New page

'''Unreleased structure'''

The entry 5giy is ON HOLD

Authors: feng yang, tao wang

Description: HSA-Palmitic acid-[RuCl5(ind)]2-
[[Category: Unreleased Structures]]
[[Category: Feng Yang, Tao Wang]]