5hob - Revision history

OCA at 10:48, 16 August 2023

2023-08-16T10:48:52Z

←Older revision		Revision as of 10:48, 16 August 2023
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	<StructureSection load='5hob' size='340' side='right'caption='[[5hob]], [[Resolution\|resolution]] 1.22Å' scene=''>		<StructureSection load='5hob' size='340' side='right'caption='[[5hob]], [[Resolution\|resolution]] 1.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Human Human~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5HOB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HOB FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 1.220013Å</td></tr>
-	<tr id='~~related~~'><td class="sblockLbl"><b>[[~~Related_structure~~\|~~Related~~:]]</b></td><td class="sblockDat"~~>[[2kby\|2kby]], [[4a9z\|4a9z]], [[5hoc\|5hoc]], [[2nb1\|2nb1]]</td></tr>~~	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	~~<tr~~ id~~='gene'><td class~~="~~sblockLbl~~"><~~b>[[Gene\|Gene~~:~~]]</b~~></td>~~<td class="sblockDat">TP73, P73 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [https://pdbe.org/5hob PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [https://www.ebi.ac.uk/pdbsum/5hob PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [~~http~~://pdbe.org/5hob PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5hob PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>	+
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>	+	[https://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>

	==See Also==		==See Also==
Line 18:		Line 17:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: ~~Human~~]]	+	[[Category: Homo sapiens]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Coutandin, D]]	+	[[Category: Coutandin D]]
-	[[Category: Dotsch, V]]	+	[[Category: Dotsch V]]
-	[[Category: Knapp, S]]	+	[[Category: Knapp S]]
-	[[Category: Krojer, T]]	+	[[Category: Krojer T]]
-	[[Category: Mathea, S]]	+	[[Category: Mathea S]]
-	[[Category: Salah, E]]	+	[[Category: Salah E]]
-	~~[[Category: Hetero-tetramerization]]~~	+
-	~~[[Category: Homo-tetramerization mutant]]~~	+
-	~~[[Category: P73]]~~	+
-	~~[[Category: Tetramerization domain]]~~	+
-	~~[[Category: Transcription]]~~	+
-	~~[[Category: Transcription factor~~]]	+

OCA at 08:25, 27 May 2020

2020-05-27T08:25:46Z

←Older revision		Revision as of 08:25, 27 May 2020
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	==p73 homo-tetramerization domain mutant I==		==p73 homo-tetramerization domain mutant I==
-	<StructureSection load='5hob' size='340' side='right' caption='[[5hob]], [[Resolution\|resolution]] 1.22Å' scene=''>	+	<StructureSection load='5hob' size='340' side='right'caption='[[5hob]], [[Resolution\|resolution]] 1.22Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5HOB FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HOB FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kby\|2kby]], [[4a9z\|4a9z]], [[5hoc\|5hoc]], [[2nb1\|2nb1]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kby\|2kby]], [[4a9z\|4a9z]], [[5hoc\|5hoc]], [[2nb1\|2nb1]]</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [http://pdbe.org/5hob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [http://www.ebi.ac.uk/pdbsum/5hob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">TP73, P73 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [http://pdbe.org/5hob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [http://www.ebi.ac.uk/pdbsum/5hob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
	[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>		[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
		+
		+	==See Also==
		+	*[[P73\|P73]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Human]]
		+	[[Category: Large Structures]]
	[[Category: Coutandin, D]]		[[Category: Coutandin, D]]
	[[Category: Dotsch, V]]		[[Category: Dotsch, V]]

OCA at 00:58, 20 October 2016

2016-10-20T00:58:21Z

←Older revision		Revision as of 00:58, 20 October 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5hob is ~~ON HOLD~~ ~~until Paper Publication~~	+	==p73 homo-tetramerization domain mutant I==
-		+	<StructureSection load='5hob' size='340' side='right' caption='[[5hob]], [[Resolution\|resolution]] 1.22Å' scene=''>
-	~~Authors~~:	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5hob]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HOB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HOB FirstGlance]. <br>
-	~~Description~~:	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[2kby\|2kby]], [[4a9z\|4a9z]], [[5hoc\|5hoc]], [[2nb1\|2nb1]]</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hob FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hob OCA], [http://pdbe.org/5hob PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hob RCSB], [http://www.ebi.ac.uk/pdbsum/5hob PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hob ProSAT]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/P73_HUMAN P73_HUMAN]] Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.<ref>PMID:11753569</ref> <ref>PMID:10203277</ref> <ref>PMID:18174154</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Coutandin, D]]
		+	[[Category: Dotsch, V]]
		+	[[Category: Knapp, S]]
		+	[[Category: Krojer, T]]
		+	[[Category: Mathea, S]]
		+	[[Category: Salah, E]]
		+	[[Category: Hetero-tetramerization]]
		+	[[Category: Homo-tetramerization mutant]]
		+	[[Category: P73]]
		+	[[Category: Tetramerization domain]]
		+	[[Category: Transcription]]
		+	[[Category: Transcription factor]]

OCA at 13:46, 15 May 2016

2016-05-15T13:46:12Z

←Older revision		Revision as of 13:46, 15 May 2016
Line 3:		Line 3:
	The entry 5hob is ON HOLD until Paper Publication		The entry 5hob is ON HOLD until Paper Publication

-	Authors: ~~Coutandin, D., Krojer, T., Salah, E., Mathea, S., Knapp, S., Dotsch, V.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Knapp, S]]
-	[[Category: Krojer, T]]
-	[[Category: Mathea, S]]
-	[[Category: Coutandin, D]]
-	[[Category: Dotsch, V]]
-	[[Category: Salah, E]]

OCA: Protected "5hob" [edit=sysop:move=sysop]

2016-01-28T00:58:11Z

Protected "5hob" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:58, 28 January 2016

OCA: New page: '''Unreleased structure''' The entry 5hob is ON HOLD until Paper Publication Authors: Coutandin, D., Krojer, T., Salah, E., Mathea, S., Knapp, S., Dotsch, V. Description: [[Category: ...

2016-01-28T00:58:09Z

New page: '''Unreleased structure''' The entry 5hob is ON HOLD until Paper Publication Authors: Coutandin, D., Krojer, T., Salah, E., Mathea, S., Knapp, S., Dotsch, V. Description: [[Category: ...

New page

'''Unreleased structure'''

The entry 5hob is ON HOLD until Paper Publication

Authors: Coutandin, D., Krojer, T., Salah, E., Mathea, S., Knapp, S., Dotsch, V.

Description:
[[Category: Unreleased Structures]]
[[Category: Knapp, S]]
[[Category: Krojer, T]]
[[Category: Mathea, S]]
[[Category: Coutandin, D]]
[[Category: Dotsch, V]]
[[Category: Salah, E]]