5hvd - Revision history

OCA at 10:55, 16 August 2023

2023-08-16T10:55:05Z

←Older revision		Revision as of 10:55, 16 August 2023
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	<StructureSection load='5hvd' size='340' side='right'caption='[[5hvd]], [[Resolution\|resolution]] 2.60Å' scene=''>		<StructureSection load='5hvd' size='340' side='right'caption='[[5hvd]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HVD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5HVD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hvd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Magnetococcus_marinus_MC-1 Magnetococcus marinus MC-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HVD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.6Å</td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hvd OCA], [~~http~~://pdbe.org/5hvd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5hvd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5hvd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5hvd ProSAT]</span></td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hvd OCA], [https://pdbe.org/5hvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hvd RCSB], [https://www.ebi.ac.uk/pdbsum/5hvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hvd ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0L5S6_MAGMM A0L5S6_MAGMM]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	</div>		</div>
	<div class="pdbe-citations 5hvd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5hvd" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Ion channels 3D structures\|Ion channels 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Booker, J E~~]]	+	[[Category: Magnetococcus marinus MC-1]]
-	[[Category: ~~Naylor, C E~~]]	+	[[Category: Booker JE]]
-	[[Category: ~~Sula, A~~]]	+	[[Category: Naylor CE]]
-	[[Category: ~~Wallace, B~~ A]]	+	[[Category: Sula A]]
-	[[Category: ~~Integral membrane voltage gated sodium channel]]~~	+	[[Category: Wallace BA]]
-	~~[[Category: Transport protein~~]]	+

OCA at 08:33, 27 May 2020

2020-05-27T08:33:20Z

←Older revision		Revision as of 08:33, 27 May 2020
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	==Full length Open-form Sodium Channel NavMs I218C==		==Full length Open-form Sodium Channel NavMs I218C==
-	<StructureSection load='5hvd' size='340' side='right' caption='[[5hvd]], [[Resolution\|resolution]] 2.60Å' scene=''>	+	<StructureSection load='5hvd' size='340' side='right'caption='[[5hvd]], [[Resolution\|resolution]] 2.60Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5hvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HVD OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5HVD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5hvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HVD OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5HVD FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hvd OCA], [http://pdbe.org/5hvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hvd RCSB], [http://www.ebi.ac.uk/pdbsum/5hvd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hvd ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hvd OCA], [http://pdbe.org/5hvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hvd RCSB], [http://www.ebi.ac.uk/pdbsum/5hvd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hvd ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Large Structures]]
	[[Category: Booker, J E]]		[[Category: Booker, J E]]
	[[Category: Naylor, C E]]		[[Category: Naylor, C E]]

OCA at 09:32, 11 March 2017

2017-03-11T09:32:45Z

←Older revision		Revision as of 09:32, 11 March 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5hvd is ~~ON HOLD until Paper~~ Publication	+	==Full length Open-form Sodium Channel NavMs I218C==
		+	<StructureSection load='5hvd' size='340' side='right' caption='[[5hvd]], [[Resolution\|resolution]] 2.60Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5hvd]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HVD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HVD FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=12P:DODECAETHYLENE+GLYCOL'>12P</scene>, <scene name='pdbligand=2CV:HEGA-10'>2CV</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hvd OCA], [http://pdbe.org/5hvd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hvd RCSB], [http://www.ebi.ac.uk/pdbsum/5hvd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hvd ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Voltage-gated sodium channels (Navs) play essential roles in excitable tissues, with their activation and opening resulting in the initial phase of the action potential. The cycling of Navs through open, closed and inactivated states, and their closely choreographed relationships with the activities of other ion channels lead to exquisite control of intracellular ion concentrations in both prokaryotes and eukaryotes. Here we present the 2.45 A resolution crystal structure of the complete NavMs prokaryotic sodium channel in a fully open conformation. A canonical activated conformation of the voltage sensor S4 helix, an open selectivity filter leading to an open activation gate at the intracellular membrane surface and the intracellular C-terminal domain are visible in the structure. It includes a heretofore unseen interaction motif between W77 of S3, the S4-S5 interdomain linker, and the C-terminus, which is associated with regulation of opening and closing of the intracellular gate.

-	~~Authors~~:	+	The complete structure of an activated open sodium channel.,Sula A, Booker J, Ng LC, Naylor CE, DeCaen PG, Wallace BA Nat Commun. 2017 Feb 16;8:14205. doi: 10.1038/ncomms14205. PMID:28205548<ref>PMID:28205548</ref>

-	~~Description~~:	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5hvd" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Booker, J E]]
		+	[[Category: Naylor, C E]]
		+	[[Category: Sula, A]]
		+	[[Category: Wallace, B A]]
		+	[[Category: Integral membrane voltage gated sodium channel]]
		+	[[Category: Transport protein]]

OCA at 14:10, 9 December 2016

2016-12-09T14:10:32Z

←Older revision		Revision as of 14:10, 9 December 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5hvd is ON HOLD	+	The entry 5hvd is ON HOLD until Paper Publication

	Authors:		Authors:

OCA at 13:56, 15 May 2016

2016-05-15T13:56:22Z

←Older revision		Revision as of 13:56, 15 May 2016
Line 3:		Line 3:
	The entry 5hvd is ON HOLD		The entry 5hvd is ON HOLD

-	Authors: ~~Sula, A., Booker, J.E., Naylor, C.E., Wallace, B.A.~~	+	Authors:

	Description:		Description:
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Wallace, B.A]]
-	[[Category: Sula, A]]
-	[[Category: Booker, J.E]]
-	[[Category: Naylor, C.E]]

OCA: Protected "5hvd" [edit=sysop:move=sysop]

2016-02-03T14:24:52Z

Protected "5hvd" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:24, 3 February 2016

OCA: New page: '''Unreleased structure''' The entry 5hvd is ON HOLD Authors: Sula, A., Booker, J.E., Naylor, C.E., Wallace, B.A. Description: Category: Unreleased Structures [[Category: Wallace,...

2016-02-03T14:24:50Z

New page: '''Unreleased structure''' The entry 5hvd is ON HOLD Authors: Sula, A., Booker, J.E., Naylor, C.E., Wallace, B.A. Description: Category: Unreleased Structures [[Category: Wallace,...

New page

'''Unreleased structure'''

The entry 5hvd is ON HOLD

Authors: Sula, A., Booker, J.E., Naylor, C.E., Wallace, B.A.

Description:
[[Category: Unreleased Structures]]
[[Category: Wallace, B.A]]
[[Category: Sula, A]]
[[Category: Booker, J.E]]
[[Category: Naylor, C.E]]