5iiq - Revision history

OCA at 13:54, 30 August 2023

2023-08-30T13:54:38Z

←Older revision		Revision as of 13:54, 30 August 2023
Line 3:		Line 3:
	<StructureSection load='5iiq' size='340' side='right'caption='[[5iiq]], [[Resolution\|resolution]] 3.03Å' scene=''>		<StructureSection load='5iiq' size='340' side='right'caption='[[5iiq]], [[Resolution\|resolution]] 3.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_18824 Atcc 18824~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=POP:PYROPHOSPHATE+2~~-~~'>POP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 3.03Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~VTC4, PHM3, YJL012C, J1345 ([http~~:/~~/www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=4932 ATCC 18824])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [~~http~~://pdbe.org/5iiq PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5iiq PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5iiq ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [https://pdbe.org/5iiq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [https://www.ebi.ac.uk/pdbsum/5iiq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5iiq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/VTC4_YEAST VTC4_YEAST]] Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation.<ref>PMID:11102525</ref> <ref>PMID:11823419</ref> <ref>PMID:12584253</ref>	+	[https://www.uniprot.org/uniprot/VTC4_YEAST VTC4_YEAST] Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation.<ref>PMID:11102525</ref> <ref>PMID:11823419</ref> <ref>PMID:12584253</ref>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 23:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 18824]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Hothorn, M~~]]	+	[[Category: Saccharomyces cerevisiae]]
-	[[Category: ~~Wild, R~~]]	+	[[Category: Hothorn M]]
-	[[Category: ~~Alpha-helical hairpin]]~~	+	[[Category: Wild R]]
-	~~[[Category: Chaperone]]~~	+
-	~~[[Category: Helical bundle]]~~	+
-	~~[[Category: Inositol phosphate binding]]~~	+
-	~~[[Category: Protein-protein interaction]]~~	+
-	~~[[Category: Transferase~~]]	+

OCA at 07:20, 3 June 2020

2020-06-03T07:20:01Z

←Older revision		Revision as of 07:20, 3 June 2020
Line 1:		Line 1:

	==Structure of the SPX-TTM domain fragment of the yeast inorganic polyphophate polymerase Vtc4 (form B).==		==Structure of the SPX-TTM domain fragment of the yeast inorganic polyphophate polymerase Vtc4 (form B).==
-	<StructureSection load='5iiq' size='340' side='right' caption='[[5iiq]], [[Resolution\|resolution]] 3.03Å' scene=''>	+	<StructureSection load='5iiq' size='340' side='right'caption='[[5iiq]], [[Resolution\|resolution]] 3.03Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_18824 Atcc 18824]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [http://pdbe.org/5iiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [http://www.ebi.ac.uk/pdbsum/5iiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iiq ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">VTC4, PHM3, YJL012C, J1345 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 ATCC 18824])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [http://pdbe.org/5iiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [http://www.ebi.ac.uk/pdbsum/5iiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iiq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 22:		Line 23:
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 18824]]
		+	[[Category: Large Structures]]
	[[Category: Hothorn, M]]		[[Category: Hothorn, M]]
	[[Category: Wild, R]]		[[Category: Wild, R]]

OCA at 09:19, 3 October 2016

2016-10-03T09:19:23Z

←Older revision		Revision as of 09:19, 3 October 2016
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>		<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [http://pdbe.org/5iiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [http://www.ebi.ac.uk/pdbsum/5iiq PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [http://pdbe.org/5iiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [http://www.ebi.ac.uk/pdbsum/5iiq PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5iiq ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 12:08, 13 May 2016

2016-05-13T12:08:14Z

←Older revision		Revision as of 12:08, 13 May 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5iiq is ~~ON HOLD~~ ~~until Paper~~ Publication	+	==Structure of the SPX-TTM domain fragment of the yeast inorganic polyphophate polymerase Vtc4 (form B).==
		+	<StructureSection load='5iiq' size='340' side='right' caption='[[5iiq]], [[Resolution\|resolution]] 3.03Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5iiq]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5IIQ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5IIQ FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5iiq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5iiq OCA], [http://pdbe.org/5iiq PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5iiq RCSB], [http://www.ebi.ac.uk/pdbsum/5iiq PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/VTC4_YEAST VTC4_YEAST]] Component of the vacuolar transporter chaperone (VTC) complex, which plays a role in vacuolar membrane fusion. Required for SEC18/NSF activity in SNARE priming, membrane binding of LMA1 and V(0) trans-complex formation.<ref>PMID:11102525</ref> <ref>PMID:11823419</ref> <ref>PMID:12584253</ref>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Phosphorus is a macronutrient taken up by cells as inorganic phosphate (Pi). How cells sense cellular Pilevels is poorly characterized. Here we report that SPX domains, which are found in eukaryotic phosphate transporters, signaling proteins and inorganic polyphosphate polymerases, provide a basic binding surface for inositol polyphosphate signaling molecules (InsPs), whose concentrations change in response to Piavailability. Substitutions of critical binding surface residues impair InsP binding in vitro, inorganic polyphosphate synthesis in yeast and Pitransport inArabidopsis In plants, InsPs trigger the association of SPX proteins with transcription factors to regulate Pistarvation responses. We propose that InsPs communicate cytosolic Pilevels to SPX domains and enable them to interact with a multitude of proteins to regulate Piuptake, transport and storage in fungi, plants and animals.

-	~~Authors:~~ Wild, R., ~~Hothorn~~, M.	+	Control of eukaryotic phosphate homeostasis by inositol polyphosphate sensor domains.,Wild R, Gerasimaite R, Jung JY, Truffault V, Pavlovic I, Schmidt A, Saiardi A, Jessen HJ, Poirier Y, Hothorn M, Mayer A Science. 2016 Apr 14. pii: aad9858. PMID:27080106<ref>PMID:27080106</ref>

-	~~Description:~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category: Unreleased Structures]]~~	+	</div>
-	~~[[Category~~: ~~Wild, R]]~~	+	<div class="pdbe-citations 5iiq" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Hothorn, M]]		[[Category: Hothorn, M]]
		+	[[Category: Wild, R]]
		+	[[Category: Alpha-helical hairpin]]
		+	[[Category: Chaperone]]
		+	[[Category: Helical bundle]]
		+	[[Category: Inositol phosphate binding]]
		+	[[Category: Protein-protein interaction]]
		+	[[Category: Transferase]]

OCA: Protected "5iiq" [edit=sysop:move=sysop]

2016-03-10T02:23:23Z

Protected "5iiq" [edit=sysop:move=sysop]

←Older revision

Revision as of 02:23, 10 March 2016

OCA: New page: '''Unreleased structure''' The entry 5iiq is ON HOLD until Paper Publication Authors: Wild, R., Hothorn, M. Description: Category: Unreleased Structures Category: Wild, R [[Ca...

2016-03-10T02:23:22Z

New page: '''Unreleased structure''' The entry 5iiq is ON HOLD until Paper Publication Authors: Wild, R., Hothorn, M. Description: Category: Unreleased Structures Category: Wild, R [[Ca...

New page

'''Unreleased structure'''

The entry 5iiq is ON HOLD until Paper Publication

Authors: Wild, R., Hothorn, M.

Description:
[[Category: Unreleased Structures]]
[[Category: Wild, R]]
[[Category: Hothorn, M]]