5jxl - Revision history

OCA at 09:17, 20 March 2024

2024-03-20T09:17:49Z

←Older revision		Revision as of 09:17, 20 March 2024
Line 9:		Line 9:
	== Function ==		== Function ==
	[https://www.uniprot.org/uniprot/A0A1L1QK18_CAMJ8 A0A1L1QK18_CAMJ8]		[https://www.uniprot.org/uniprot/A0A1L1QK18_CAMJ8 A0A1L1QK18_CAMJ8]
-	<div style="background-color:#fffaf0;">
-	== Publication Abstract from PubMed ==
-	The bacterial flagellar hook is a tubular helical structure made by the polymerization of multiple copies of a protein, FlgE. Here we report the structure of the hook from Campylobacter jejuni by cryo-electron microscopy at a resolution of 3.5 A. On the basis of this structure, we show that the hook is stabilized by intricate inter-molecular interactions between FlgE molecules. Extra domains in FlgE, found only in Campylobacter and in related bacteria, bring more stability and robustness to the hook. Functional experiments suggest that Campylobacter requires an unusually strong hook to swim without its flagella being torn off. This structure reveals details of the quaternary organization of the hook that consists of 11 protofilaments. Previous study of the flagellar filament of Campylobacter by electron microscopy showed its quaternary structure made of seven protofilaments. Therefore, this study puts in evidence the difference between the quaternary structures of a bacterial filament and its hook.
-
-	Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions.,Matsunami H, Barker CS, Yoon YH, Wolf M, Samatey FA Nat Commun. 2016 Nov 4;7:13425. doi: 10.1038/ncomms13425. PMID:27811912<ref>PMID:27811912</ref>
-
-	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	</div>
-	<div class="pdbe-citations 5jxl" style="background-color:#fffaf0;"></div>

	==See Also==		==See Also==
	*[[Flagellar protein 3D structures\|Flagellar protein 3D structures]]		*[[Flagellar protein 3D structures\|Flagellar protein 3D structures]]
	*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]		*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]
-	== References ==
-	<references/>
	__TOC__		__TOC__
	</SX>		</SX>

OCA at 19:14, 20 September 2023

2023-09-20T19:14:12Z

←Older revision		Revision as of 19:14, 20 September 2023
Line 3:		Line 3:
	<SX load='5jxl' size='340' side='right' viewer='molstar' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>		<SX load='5jxl' size='340' side='right' viewer='molstar' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5JXL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5JXL FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5jxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxl OCA], [~~http~~://pdbe.org/5jxl PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5jxl RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5jxl PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxl ProSAT]</span></td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution\|Resolution]] 3.5Å</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5jxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxl OCA], [https://pdbe.org/5jxl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5jxl RCSB], [https://www.ebi.ac.uk/pdbsum/5jxl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxl ProSAT]</span></td></tr>
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/A0A1L1QK18_CAMJ8 A0A1L1QK18_CAMJ8]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
Line 19:		Line 22:
	*[[Flagellar protein 3D structures\|Flagellar protein 3D structures]]		*[[Flagellar protein 3D structures\|Flagellar protein 3D structures]]
	*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]		*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]
-	*[[User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch\|User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch]]
	== References ==		== References ==
	<references/>		<references/>
Line 26:		Line 28:
	[[Category: Campylobacter jejuni subsp. jejuni 81116]]		[[Category: Campylobacter jejuni subsp. jejuni 81116]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: Matsunami, H]]	+	[[Category: Matsunami H]]
-	[[Category: Samatey~~, F A~~]]	+	[[Category: Samatey FA]]
-	[[Category: Wolf, M]]	+	[[Category: Wolf M]]
-	~~[[Category: Campylobacter jejuni]]~~	+
-	~~[[Category: Flagellar hook]]~~	+
-	~~[[Category: Helical assembly of flge]]~~	+
-	~~[[Category: Motor protein~~]]	+

OCA at 20:25, 10 April 2020

2020-04-10T20:25:52Z

←Older revision		Revision as of 20:25, 10 April 2020
Line 3:		Line 3:
	<SX load='5jxl' size='340' side='right' viewer='molstar' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>		<SX load='5jxl' size='340' side='right' viewer='molstar' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5JXL FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5JXL FirstGlance]. <br>
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5jxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxl OCA], [http://pdbe.org/5jxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jxl RCSB], [http://www.ebi.ac.uk/pdbsum/5jxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxl ProSAT]</span></td></tr>	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5jxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxl OCA], [http://pdbe.org/5jxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jxl RCSB], [http://www.ebi.ac.uk/pdbsum/5jxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxl ProSAT]</span></td></tr>
	</table>		</table>
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">

OCA at 18:44, 6 March 2020

2020-03-06T18:44:36Z

←Older revision		Revision as of 18:44, 6 March 2020
Line 1:		Line 1:

	==Cryo-EM structure of the flagellar hook of Campylobacter jejuni==		==Cryo-EM structure of the flagellar hook of Campylobacter jejuni==
-	<~~StructureSection~~ load='5jxl' size='340' side='right'caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<SX load='5jxl' size='340' side='right' viewer='molstar' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXL FirstGlance]. <br>		<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXL FirstGlance]. <br>
Line 23:		Line 23:
	<references/>		<references/>
	__TOC__		__TOC__
-	</~~StructureSection~~>	+	</SX>
	[[Category: Campylobacter jejuni subsp. jejuni 81116]]		[[Category: Campylobacter jejuni subsp. jejuni 81116]]
	[[Category: Large Structures]]		[[Category: Large Structures]]

OCA at 16:24, 11 December 2019

2019-12-11T16:24:50Z

←Older revision		Revision as of 16:24, 11 December 2019
Line 1:		Line 1:

	==Cryo-EM structure of the flagellar hook of Campylobacter jejuni==		==Cryo-EM structure of the flagellar hook of Campylobacter jejuni==
-	<StructureSection load='5jxl' size='340' side='right' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>	+	<StructureSection load='5jxl' size='340' side='right'caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXL FirstGlance]. <br>		<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXL FirstGlance]. <br>
Line 17:		Line 17:

	==See Also==		==See Also==
		+	*[[Flagellar protein 3D structures\|Flagellar protein 3D structures]]
	*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]		*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]
	*[[User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch\|User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch]]		*[[User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch\|User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch]]
Line 24:		Line 25:
	</StructureSection>		</StructureSection>
	[[Category: Campylobacter jejuni subsp. jejuni 81116]]		[[Category: Campylobacter jejuni subsp. jejuni 81116]]
		+	[[Category: Large Structures]]
	[[Category: Matsunami, H]]		[[Category: Matsunami, H]]
	[[Category: Samatey, F A]]		[[Category: Samatey, F A]]

OCA at 07:27, 25 July 2018

2018-07-25T07:27:41Z

←Older revision		Revision as of 07:27, 25 July 2018
Line 15:		Line 15:
	</div>		</div>
	<div class="pdbe-citations 5jxl" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5jxl" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[The Bacterial Flagellar Hook\|The Bacterial Flagellar Hook]]
		+	*[[User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch\|User:Fadel A. Samatey/FlgE III/Intrinsically Disordered Flagellar Rod Stretch]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 19:36, 9 December 2016

2016-12-09T19:36:06Z

←Older revision		Revision as of 19:36, 9 December 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5jxl is ~~ON HOLD~~	+	==Cryo-EM structure of the flagellar hook of Campylobacter jejuni==
		+	<StructureSection load='5jxl' size='340' side='right' caption='[[5jxl]], [[Resolution\|resolution]] 3.50Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5jxl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_jejuni_subsp._jejuni_81116 Campylobacter jejuni subsp. jejuni 81116]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5JXL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5JXL FirstGlance]. <br>
		+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5jxl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5jxl OCA], [http://pdbe.org/5jxl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5jxl RCSB], [http://www.ebi.ac.uk/pdbsum/5jxl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5jxl ProSAT]</span></td></tr>
		+	</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The bacterial flagellar hook is a tubular helical structure made by the polymerization of multiple copies of a protein, FlgE. Here we report the structure of the hook from Campylobacter jejuni by cryo-electron microscopy at a resolution of 3.5 A. On the basis of this structure, we show that the hook is stabilized by intricate inter-molecular interactions between FlgE molecules. Extra domains in FlgE, found only in Campylobacter and in related bacteria, bring more stability and robustness to the hook. Functional experiments suggest that Campylobacter requires an unusually strong hook to swim without its flagella being torn off. This structure reveals details of the quaternary organization of the hook that consists of 11 protofilaments. Previous study of the flagellar filament of Campylobacter by electron microscopy showed its quaternary structure made of seven protofilaments. Therefore, this study puts in evidence the difference between the quaternary structures of a bacterial filament and its hook.

-	~~Authors: Matsunami~~, H., ~~Wolf~~, M., Samatey~~, F~~.A.	+	Complete structure of the bacterial flagellar hook reveals extensive set of stabilizing interactions.,Matsunami H, Barker CS, Yoon YH, Wolf M, Samatey FA Nat Commun. 2016 Nov 4;7:13425. doi: 10.1038/ncomms13425. PMID:27811912<ref>PMID:27811912</ref>

-	~~Description: Cryo-EM structure~~ of the ~~flagellar hook~~ of ~~Campylobacter jejuni~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	[[Category: ~~Unreleased Structures~~]]	+	</div>
		+	<div class="pdbe-citations 5jxl" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Campylobacter jejuni subsp. jejuni 81116]]
	[[Category: Matsunami, H]]		[[Category: Matsunami, H]]
		+	[[Category: Samatey, F A]]
	[[Category: Wolf, M]]		[[Category: Wolf, M]]
-	[[Category: ~~Samatey, F.A~~]]	+	[[Category: Campylobacter jejuni]]
		+	[[Category: Flagellar hook]]
		+	[[Category: Helical assembly of flge]]
		+	[[Category: Motor protein]]

OCA: Protected "5jxl" [edit=sysop:move=sysop]

2016-06-01T14:00:33Z

Protected "5jxl" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:00, 1 June 2016

OCA: New page: '''Unreleased structure''' The entry 5jxl is ON HOLD Authors: Matsunami, H., Wolf, M., Samatey, F.A. Description: Cryo-EM structure of the flagellar hook of Campylobacter jejuni [[Cate...

2016-06-01T14:00:32Z

New page: '''Unreleased structure''' The entry 5jxl is ON HOLD Authors: Matsunami, H., Wolf, M., Samatey, F.A. Description: Cryo-EM structure of the flagellar hook of Campylobacter jejuni [[Cate...

New page

'''Unreleased structure'''

The entry 5jxl is ON HOLD

Authors: Matsunami, H., Wolf, M., Samatey, F.A.

Description: Cryo-EM structure of the flagellar hook of Campylobacter jejuni
[[Category: Unreleased Structures]]
[[Category: Matsunami, H]]
[[Category: Wolf, M]]
[[Category: Samatey, F.A]]