5kkd - Revision history

OCA at 10:48, 27 September 2023

2023-09-27T10:48:21Z

←Older revision		Revision as of 10:48, 27 September 2023
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	<StructureSection load='5kkd' size='340' side='right'caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>		<StructureSection load='5kkd' size='340' side='right'caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_29906 Atcc 29906~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5KKD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5KKD FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat"~~><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>~~	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.13Å</td></tr>
-	~~<tr~~ id~~='related'><td class~~="~~sblockLbl~~">~~<b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5kf3\|5kf3]]~~, [[~~5kdk~~\|~~5kdk]], [[5keh\|5keh~~]]</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~hpmA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=~~5&id=584 ATCC 29906])~~</td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [https://pdbe.org/5kkd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [https://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [~~http~~://pdbe.org/5kkd PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>	+
	</table>		</table>
		+	== Function ==
		+	[https://www.uniprot.org/uniprot/HLYA_PROMI HLYA_PROMI]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 29906]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bhattacharyya, B~~]]	+	[[Category: Proteus mirabilis]]
-	[[Category: ~~Novak, W R.P~~]]	+	[[Category: Bhattacharyya B]]
-	[[Category: ~~Weaver, T M~~]]	+	[[Category: Novak WRP]]
-	[[Category: ~~Beta helix]]~~	+	[[Category: Weaver TM]]
-	~~[[Category: Beta solenoid]]~~	+
-	~~[[Category: Hemolysin]]~~	+
-	~~[[Category: Toxin]]~~	+
-	~~[[Category: Two partner secretion~~]]	+

OCA at 07:45, 27 November 2019

2019-11-27T07:45:02Z

←Older revision		Revision as of 07:45, 27 November 2019
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	==Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition==		==Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition==
-	<StructureSection load='5kkd' size='340' side='right' caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>	+	<StructureSection load='5kkd' size='340' side='right'caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29906 Atcc 29906]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KKD FirstGlance]. <br>		<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29906 Atcc 29906]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KKD FirstGlance]. <br>
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	</div>		</div>
	<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Hemolysin 3D structures\|Hemolysin 3D structures]]
	== References ==		== References ==
	<references/>		<references/>
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	</StructureSection>		</StructureSection>
	[[Category: Atcc 29906]]		[[Category: Atcc 29906]]
		+	[[Category: Large Structures]]
	[[Category: Bhattacharyya, B]]		[[Category: Bhattacharyya, B]]
	[[Category: Novak, W R.P]]		[[Category: Novak, W R.P]]

OCA at 18:23, 15 November 2017

2017-11-15T18:23:42Z

←Older revision		Revision as of 18:23, 15 November 2017
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	<StructureSection load='5kkd' size='340' side='right' caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>		<StructureSection load='5kkd' size='340' side='right' caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KKD FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_29906 Atcc 29906]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KKD FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5kf3\|5kf3]], [[5kdk\|5kdk]], [[5keh\|5keh]]</td></tr>		<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5kf3\|5kf3]], [[5kdk\|5kdk]], [[5keh\|5keh]]</td></tr>
		+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">hpmA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=584 ATCC 29906])</td></tr>
	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [http://pdbe.org/5kkd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [http://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [http://pdbe.org/5kkd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [http://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>
	</table>		</table>
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	</div>		</div>
	<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>
-
-	==See Also==
-	*[[Hemolysin\|Hemolysin]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 29906]]
	[[Category: Bhattacharyya, B]]		[[Category: Bhattacharyya, B]]
	[[Category: Novak, W R.P]]		[[Category: Novak, W R.P]]

OCA at 09:26, 3 August 2017

2017-08-03T09:26:18Z

←Older revision		Revision as of 09:26, 3 August 2017
Line 17:		Line 17:
	</div>		</div>
	<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Hemolysin\|Hemolysin]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 09:06, 17 May 2017

2017-05-17T09:06:13Z

←Older revision		Revision as of 09:06, 17 May 2017
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	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [http://pdbe.org/5kkd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [http://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>		<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [http://pdbe.org/5kkd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [http://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>
	</table>		</table>
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	Wild-type and variant forms of HpmA265 (truncated hemolysin A) from Proteus mirabilis reveal a right-handed, parallel beta-helix capped and flanked by segments of antiparallel beta-strands. The low-salt crystal structures form a dimeric structure via the implementation of on-edge main-chain hydrogen bonds donated by residues 243-263 of adjacent monomers. Surprisingly, in the high-salt structures of two variants, Y134A and Q125A-Y134A, a new dimeric interface is formed via main-chain hydrogen bonds donated by residues 203-215 of adjacent monomers, and a previously unobserved tetramer is formed. In addition, an eight-stranded antiparallel beta-sheet is formed from the flap regions of crystallographically related monomers in the high-salt structures. This new interface is possible owing to additional proteolysis of these variants after Tyr240. The interface formed in the high-salt crystal forms of hemolysin A variants may mimic the on-edge beta-strand positioning used in template-assisted hemolytic activity.
		+
		+	Proteolysis of truncated hemolysin A yields a stable dimerization interface.,Novak WR, Bhattacharyya B, Grilley DP, Weaver TM Acta Crystallogr F Struct Biol Commun. 2017 Mar 1;73(Pt 3):138-145. doi:, 10.1107/S2053230X17002102. Epub 2017 Feb 21. PMID:28291749<ref>PMID:28291749</ref>
		+
		+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
		+	</div>
		+	<div class="pdbe-citations 5kkd" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>

OCA at 16:22, 22 March 2017

2017-03-22T16:22:36Z

←Older revision		Revision as of 16:22, 22 March 2017
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry 5kkd is ON HOLD until Paper Publication~~	+	==Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition==
-		+	<StructureSection load='5kkd' size='340' side='right' caption='[[5kkd]], [[Resolution\|resolution]] 2.13Å' scene=''>
-	~~Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M.~~	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5kkd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KKD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KKD FirstGlance]. <br>
-	~~Description:~~ Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	[[~~Category~~: ~~Unreleased Structures~~]]	+	<tr id='related'><td class="sblockLbl"><b>[[Related_structure\|Related:]]</b></td><td class="sblockDat">[[5kf3\|5kf3]], [[5kdk\|5kdk]], [[5keh\|5keh]]</td></tr>
-	[[~~Category~~: ~~Novak~~, W.R.P]]	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kkd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kkd OCA], [http://pdbe.org/5kkd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kkd RCSB], [http://www.ebi.ac.uk/pdbsum/5kkd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kkd ProSAT]</span></td></tr>
		+	</table>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bhattacharyya, B]]		[[Category: Bhattacharyya, B]]
-	[[Category: Weaver, T.M]]	+	[[Category: Novak, W R.P]]
		+	[[Category: Weaver, T M]]
		+	[[Category: Beta helix]]
		+	[[Category: Beta solenoid]]
		+	[[Category: Hemolysin]]
		+	[[Category: Toxin]]
		+	[[Category: Two partner secretion]]

OCA at 10:18, 9 March 2017

2017-03-09T10:18:41Z

←Older revision		Revision as of 10:18, 9 March 2017
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	Description: Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition		Description: Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Weaver, T.M]]
	[[Category: Novak, W.R.P]]		[[Category: Novak, W.R.P]]
	[[Category: Bhattacharyya, B]]		[[Category: Bhattacharyya, B]]
		+	[[Category: Weaver, T.M]]

OCA at 09:22, 14 July 2016

2016-07-14T09:22:30Z

←Older revision		Revision as of 09:22, 14 July 2016
Line 1:		Line 1:
	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5kkd is ON HOLD	+	The entry 5kkd is ON HOLD until Paper Publication

	Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M.		Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M.

OCA: Protected "5kkd" [edit=sysop:move=sysop]

2016-07-13T00:28:31Z

Protected "5kkd" [edit=sysop:move=sysop]

←Older revision

Revision as of 00:28, 13 July 2016

OCA: New page: '''Unreleased structure''' The entry 5kkd is ON HOLD Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M. Description: Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms...

2016-07-13T00:28:30Z

New page: '''Unreleased structure''' The entry 5kkd is ON HOLD Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M. Description: Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms...

New page

'''Unreleased structure'''

The entry 5kkd is ON HOLD

Authors: Novak, W.R.P., Bhattacharyya, B., Weaver, T.M.

Description: Truncated hemolysin A Y134A from P. mirabilis at 2.1 Angstroms resolution crystallized in a high salt condition
[[Category: Unreleased Structures]]
[[Category: Weaver, T.M]]
[[Category: Novak, W.R.P]]
[[Category: Bhattacharyya, B]]