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5kmw - Revision history
2026-04-10T09:18:54Z
Revision history for this page on the wiki
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http://52.214.119.220/wiki/index.php?title=5kmw&diff=3887749&oldid=prev
OCA at 10:49, 27 September 2023
2023-09-27T10:49:05Z
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 10:49, 27 September 2023</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right'caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right'caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure with sequence from [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://en.wikipedia.org/wiki/<del style="color: red; font-weight: bold; text-decoration: none;">"bacillus_coli"_migula_1895 "bacillus </del>coli<del style="color: red; font-weight: bold; text-decoration: none;">" migula 1895</del>]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://<del style="color: red; font-weight: bold; text-decoration: none;">oca</del>.<del style="color: red; font-weight: bold; text-decoration: none;">weizmann.ac.il/oca-docs</del>/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure with sequence from [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://en.wikipedia.org/wiki/<ins style="color: red; font-weight: bold; text-decoration: none;">Escherichia_coli Escherichia </ins>coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://<ins style="color: red; font-weight: bold; text-decoration: none;">proteopedia</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org</ins>/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div></td></tr><tr id='<del style="color: red; font-weight: bold; text-decoration: none;">ligand</del>'><td class="sblockLbl"><b>[[<del style="color: red; font-weight: bold; text-decoration: none;">Ligand</del>|<del style="color: red; font-weight: bold; text-decoration: none;">Ligands</del>:]]</b></td><td class="sblockDat"<del style="color: red; font-weight: bold; text-decoration: none;">><scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr></del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></td></tr><tr id='<ins style="color: red; font-weight: bold; text-decoration: none;">method</ins>'><td class="sblockLbl"><b>[[<ins style="color: red; font-weight: bold; text-decoration: none;">Empirical_models</ins>|<ins style="color: red; font-weight: bold; text-decoration: none;">Method</ins>:]]</b></td><td class="sblockDat" id="<ins style="color: red; font-weight: bold; text-decoration: none;">methodDat</ins>"><ins style="color: red; font-weight: bold; text-decoration: none;">X-ray diffraction</ins>, [[<ins style="color: red; font-weight: bold; text-decoration: none;">Resolution</ins>|<ins style="color: red; font-weight: bold; text-decoration: none;">Resolution</ins>]] <ins style="color: red; font-weight: bold; text-decoration: none;">1.1&#8491;</ins></td></tr></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;"><tr </del>id<del style="color: red; font-weight: bold; text-decoration: none;">='related'><td class</del>="<del style="color: red; font-weight: bold; text-decoration: none;">sblockLbl</del>"><del style="color: red; font-weight: bold; text-decoration: none;"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u2x|5u2x]]</del>, [[<del style="color: red; font-weight: bold; text-decoration: none;">5u2y</del>|<del style="color: red; font-weight: bold; text-decoration: none;">5u2y]], [[5u2z|5u2z</del>]]</td></tr></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><tr id='<ins style="color: red; font-weight: bold; text-decoration: none;">ligand</ins>'><td class="sblockLbl"><b>[[<ins style="color: red; font-weight: bold; text-decoration: none;">Ligand</ins>|<ins style="color: red; font-weight: bold; text-decoration: none;">Ligands</ins>:]]</b></td><td class="sblockDat" id="<ins style="color: red; font-weight: bold; text-decoration: none;">ligandDat</ins>"<ins style="color: red; font-weight: bold; text-decoration: none;">></ins><<ins style="color: red; font-weight: bold; text-decoration: none;">scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'</ins>><ins style="color: red; font-weight: bold; text-decoration: none;">PNM</ins></<ins style="color: red; font-weight: bold; text-decoration: none;">scene</ins>><ins style="color: red; font-weight: bold; text-decoration: none;">, </ins><<ins style="color: red; font-weight: bold; text-decoration: none;">scene name</ins>='<ins style="color: red; font-weight: bold; text-decoration: none;">pdbligand</ins>=<ins style="color: red; font-weight: bold; text-decoration: none;">PNN</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">PENICILLIN+G'</ins>><ins style="color: red; font-weight: bold; text-decoration: none;">PNN</ins></<ins style="color: red; font-weight: bold; text-decoration: none;">scene</ins>><ins style="color: red; font-weight: bold; text-decoration: none;">, </ins><<ins style="color: red; font-weight: bold; text-decoration: none;">scene name</ins>='<ins style="color: red; font-weight: bold; text-decoration: none;">pdbligand=SO4:SULFATE+ION</ins>'><ins style="color: red; font-weight: bold; text-decoration: none;">SO4</ins></<ins style="color: red; font-weight: bold; text-decoration: none;">scene</ins>></td></tr></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><tr id='<del style="color: red; font-weight: bold; text-decoration: none;">gene</del>'><td class="sblockLbl"><b>[[<del style="color: red; font-weight: bold; text-decoration: none;">Gene</del>|<del style="color: red; font-weight: bold; text-decoration: none;">Gene</del>:]]</b></td><td class="sblockDat"<del style="color: red; font-weight: bold; text-decoration: none;">>bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&</del>id=<del style="color: red; font-weight: bold; text-decoration: none;">562 </del>"<del style="color: red; font-weight: bold; text-decoration: none;">Bacillus coli</del>" <del style="color: red; font-weight: bold; text-decoration: none;">Migula 1895])</del><<del style="color: red; font-weight: bold; text-decoration: none;">/td</del>></<del style="color: red; font-weight: bold; text-decoration: none;">tr</del>></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://<ins style="color: red; font-weight: bold; text-decoration: none;">proteopedia</ins>.<ins style="color: red; font-weight: bold; text-decoration: none;">org</ins>/fgij/fg.htm?mol=5kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kmw OCA], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://pdbe.org/5kmw PDBe], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.rcsb.org/pdb/explore.do?structureId=5kmw RCSB], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.ebi.ac.uk/pdbsum/5kmw PDBsum], [<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://prosat.h-its.org/prosat/prosatexe?pdbcode=5kmw ProSAT]</span></td></tr></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><<del style="color: red; font-weight: bold; text-decoration: none;">tr id</del>='<del style="color: red; font-weight: bold; text-decoration: none;">activity'><td class</del>=<del style="color: red; font-weight: bold; text-decoration: none;">"sblockLbl"><b>Activity</del>:<del style="color: red; font-weight: bold; text-decoration: none;"></b</del>></<del style="color: red; font-weight: bold; text-decoration: none;">td</del>><<del style="color: red; font-weight: bold; text-decoration: none;">td class="sblockDat"><span class</del>='<del style="color: red; font-weight: bold; text-decoration: none;">plainlinks</del>'><del style="color: red; font-weight: bold; text-decoration: none;">[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </del></<del style="color: red; font-weight: bold; text-decoration: none;">span</del>></td></tr></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://<del style="color: red; font-weight: bold; text-decoration: none;">oca</del>.<del style="color: red; font-weight: bold; text-decoration: none;">weizmann.ac.il/oca-docs</del>/fgij/fg.htm?mol=5kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kmw OCA], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://pdbe.org/5kmw PDBe], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://www.rcsb.org/pdb/explore.do?structureId=5kmw RCSB], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://www.ebi.ac.uk/pdbsum/5kmw PDBsum], [<del style="color: red; font-weight: bold; text-decoration: none;">http</del>://prosat.h-its.org/prosat/prosatexe?pdbcode=5kmw ProSAT]</span></td></tr></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></table></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></table></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[<del style="color: red; font-weight: bold; text-decoration: none;">[http</del>://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX<del style="color: red; font-weight: bold; text-decoration: none;">]</del>] Has strong cefotaxime-hydrolyzing activity. </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[<ins style="color: red; font-weight: bold; text-decoration: none;">https</ins>://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX] Has strong cefotaxime-hydrolyzing activity.</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==See Also==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==See Also==</div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Bacillus </del>coli <del style="color: red; font-weight: bold; text-decoration: none;">migula 1895]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Escherichia </ins>coli]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Beta-lactamase</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Large Structures]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Large Structures]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Coates<del style="color: red; font-weight: bold; text-decoration: none;">, </del>L]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Coates L]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Cooper<del style="color: red; font-weight: bold; text-decoration: none;">, J B</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Cooper <ins style="color: red; font-weight: bold; text-decoration: none;">JB</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Ginell<del style="color: red; font-weight: bold; text-decoration: none;">, S L</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Ginell <ins style="color: red; font-weight: bold; text-decoration: none;">SL</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Langan<del style="color: red; font-weight: bold; text-decoration: none;">, P S</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Langan <ins style="color: red; font-weight: bold; text-decoration: none;">PS</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Vandavasi<del style="color: red; font-weight: bold; text-decoration: none;">, V G</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Vandavasi <ins style="color: red; font-weight: bold; text-decoration: none;">VG</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: Weiss<del style="color: red; font-weight: bold; text-decoration: none;">, K L]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Weiss <ins style="color: red; font-weight: bold; text-decoration: none;">KL</ins>]]</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Acyl-enzyme]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Class a beta-lactamase]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Hydrolase]]</del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">[[Category: Substrate recognition</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div></div></td></tr>
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OCA
http://52.214.119.220/wiki/index.php?title=5kmw&diff=3120561&oldid=prev
OCA at 09:14, 4 December 2019
2019-12-04T09:14:27Z
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 09:14, 4 December 2019</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>==TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right' caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right'caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td></tr>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Function ==</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity. </div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity. </div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>==See Also==</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Bacillus coli migula 1895]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Bacillus coli migula 1895]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Beta-lactamase]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Beta-lactamase]]</div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Large Structures]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Coates, L]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Coates, L]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Cooper, J B]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Cooper, J B]]</div></td></tr>
</table>
OCA
http://52.214.119.220/wiki/index.php?title=5kmw&diff=2804239&oldid=prev
OCA at 13:01, 6 November 2017
2017-11-06T13:01:03Z
<p></p>
<table style="background-color: white; color:black;">
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 13:01, 6 November 2017</td>
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<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right' caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><StructureSection load='5kmw' size='340' side='right' caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>== Structural highlights ==</div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><table><tr><td colspan='2'>[[5kmw]] is a 1 chain structure <ins style="color: red; font-weight: bold; text-decoration: none;">with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]</ins>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KMW FirstGlance]. <br></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u2x|5u2x]], [[5u2y|5u2y]], [[5u2z|5u2z]]</td></tr></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5u2x|5u2x]], [[5u2y|5u2y]], [[5u2z|5u2z]]</td></tr></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">bla ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr></div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kmw OCA], [http://pdbe.org/5kmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kmw RCSB], [http://www.ebi.ac.uk/pdbsum/5kmw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kmw ProSAT]</span></td></tr></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kmw OCA], [http://pdbe.org/5kmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kmw RCSB], [http://www.ebi.ac.uk/pdbsum/5kmw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kmw ProSAT]</span></td></tr></div></td></tr>
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<td colspan="2" class="diff-lineno">Line 14:</td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>__TOC__</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div></StructureSection></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: Bacillus coli migula 1895]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Beta-lactamase]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Beta-lactamase]]</div></td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Coates, L]]</div></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"><div>[[Category: Coates, L]]</div></td></tr>
</table>
OCA
http://52.214.119.220/wiki/index.php?title=5kmw&diff=2727721&oldid=prev
OCA at 09:36, 11 March 2017
2017-03-11T09:36:26Z
<p></p>
<table style="background-color: white; color:black;">
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
<tr>
<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 09:36, 11 March 2017</td>
</tr>
<tr><td colspan="2" class="diff-lineno">Line 1:</td>
<td colspan="2" class="diff-lineno">Line 1:</td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>'''Unreleased structure'''</div></td><td colspan="2"> </td></tr>
<tr><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td><td class='diff-marker'> </td><td style="background: #eee; color:black; font-size: smaller;"></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">The entry </del>5kmw is <del style="color: red; font-weight: bold; text-decoration: none;">ON HOLD </del></div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">==TOHO1 Beta lactamase mutant E166A/R274N/R276N -benzyl penicillin complex==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><StructureSection load='</ins>5kmw<ins style="color: red; font-weight: bold; text-decoration: none;">' size='340' side='right' caption='[[5kmw]], [[Resolution|resolution]] 1.10&Aring;' scene=''></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Authors</del>: </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Structural highlights ==</ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div> </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><table><tr><td colspan='2'>[[5kmw]] </ins>is <ins style="color: red; font-weight: bold; text-decoration: none;">a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5KMW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5KMW FirstGlance]. <br></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div><del style="color: red; font-weight: bold; text-decoration: none;">Description</del>: </div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PNM:OPEN+FORM+-+PENICILLIN+G'>PNM</scene>, <scene name='pdbligand=PNN:PENICILLIN+G'>PNN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr></ins></div></td></tr>
<tr><td class='diff-marker'>-</td><td style="background: #ffa; color:black; font-size: smaller;"><div>[[Category: <del style="color: red; font-weight: bold; text-decoration: none;">Unreleased Structures</del>]]</div></td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related</ins>:<ins style="color: red; font-weight: bold; text-decoration: none;">]]</b></td><td class="sblockDat">[[5u2x|5u2x]], [[5u2y|5u2y]], [[5u2z|5u2z]]</td></tr></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5kmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5kmw OCA], [http://pdbe.org/5kmw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5kmw RCSB], [http://www.ebi.ac.uk/pdbsum/5kmw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5kmw ProSAT]</span></td></tr></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></table></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">== Function ==</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[http://www.uniprot.org/uniprot/BLT1_ECOLX BLT1_ECOLX]] Has strong cefotaxime-hydrolyzing activity. </ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">__TOC__</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;"></StructureSection></ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Beta-lactamase]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Coates, L]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Cooper, J B]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Ginell, S L]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Langan, P S]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Vandavasi, V G]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Weiss, K L]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Acyl-enzyme]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category: Class a beta-lactamase]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div><ins style="color: red; font-weight: bold; text-decoration: none;">[[Category</ins>: <ins style="color: red; font-weight: bold; text-decoration: none;">Hydrolase]]</ins></div></td></tr>
<tr><td colspan="2"> </td><td class='diff-marker'>+</td><td style="background: #cfc; color:black; font-size: smaller;"><div>[[Category: <ins style="color: red; font-weight: bold; text-decoration: none;">Substrate recognition</ins>]]</div></td></tr>
</table>
OCA
http://52.214.119.220/wiki/index.php?title=5kmw&diff=2613966&oldid=prev
OCA: Protected "5kmw" [edit=sysop:move=sysop]
2016-07-13T00:34:51Z
<p>Protected "<a href="/wiki/index.php/5kmw" title="5kmw">5kmw</a>" [edit=sysop:move=sysop]</p>
<table style="background-color: white; color:black;">
<col class='diff-marker' />
<col class='diff-content' />
<col class='diff-marker' />
<col class='diff-content' />
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<td colspan='2' style="background-color: white; color:black;">←Older revision</td>
<td colspan='2' style="background-color: white; color:black;">Revision as of 00:34, 13 July 2016</td>
</tr>
</table>
OCA
http://52.214.119.220/wiki/index.php?title=5kmw&diff=2613965&oldid=prev
OCA: New page: '''Unreleased structure''' The entry 5kmw is ON HOLD Authors: Description: Category: Unreleased Structures
2016-07-13T00:34:49Z
<p>New page: '''Unreleased structure''' The entry 5kmw is ON HOLD Authors: Description: <a href="/wiki/index.php/Category:Unreleased_Structures" title="Category:Unreleased Structures">Category: Unreleased Structures</a></p>
<p><b>New page</b></p><div>'''Unreleased structure'''<br />
<br />
The entry 5kmw is ON HOLD <br />
<br />
Authors: <br />
<br />
Description: <br />
[[Category: Unreleased Structures]]</div>
OCA