5l1y - Revision history

OCA: Redirecting to 6bf2

2017-11-08T07:29:17Z

Redirecting to 6bf2

←Older revision		Revision as of 07:29, 8 November 2017
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-		+	#REDIRECT [[6bf2]] This PDB entry is obsolete and replaced by 6bf2
-	~~==Solution structure of a Bcl-xL S62E mutant==~~	+
-	~~<StructureSection load='5l1y' size='340' side='right' caption='~~[[~~5l1y]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>~~	+
-	~~== Structural highlights ==~~	+
-	~~<table><tr><td colspan='2'>[[5l1y~~]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L1Y FirstGlance]. <br>	+
-	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l1y OCA], [http://pdbe.org/5l1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l1y RCSB], [http://www.ebi.ac.uk/pdbsum/5l1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l1y ProSAT]</span></td></tr>	+
-	~~</table>~~	+
-	~~== Function ==~~	+
-	~~[[http://www.uniprot.org/uniprot/B2CL1_HUMAN B2CL1_HUMAN]] Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death~~ by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref> Isoform Bcl-X(S) promotes apoptosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref>	+
-	~~== References ==~~	+
-	~~<references/>~~	+
-	~~__TOC__~~	+
-	~~</StructureSection>~~	+
-	~~[[Category: Follis, A V]]~~	+
-	~~[[Category: Kriwacki, R]]~~	+
-	~~[[Category: Apoptosis]]~~	+

OCA at 10:34, 7 October 2017

2017-10-07T10:34:35Z

←Older revision		Revision as of 10:34, 7 October 2017
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-	'''Unreleased structure'''

-	~~The entry~~ 5l1y ~~is ON HOLD until Paper Publication~~	+	==Solution structure of a Bcl-xL S62E mutant==
-		+	<StructureSection load='5l1y' size='340' side='right' caption='[[5l1y]], [[NMR_Ensembles_of_Models \| 20 NMR models]]' scene=''>
-	~~Authors~~: ~~Follis~~, A.V., ~~Kriwacki~~, R.	+	== Structural highlights ==
-		+	<table><tr><td colspan='2'>[[5l1y]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L1Y FirstGlance]. <br>
-	~~Description~~: ~~Solution structure~~ of a Bcl-~~xL S62E mutant~~	+	</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l1y OCA], [http://pdbe.org/5l1y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l1y RCSB], [http://www.ebi.ac.uk/pdbsum/5l1y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l1y ProSAT]</span></td></tr>
-	[[Category: ~~Unreleased Structures~~]]	+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/B2CL1_HUMAN B2CL1_HUMAN]] Potent inhibitor of cell death. Inhibits activation of caspases (By similarity). Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref> Isoform Bcl-X(S) promotes apoptosis.<ref>PMID:19917720</ref> <ref>PMID:21840391</ref>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
		+	[[Category: Follis, A V]]
	[[Category: Kriwacki, R]]		[[Category: Kriwacki, R]]
-	[[Category: ~~Follis, A.V~~]]	+	[[Category: Apoptosis]]

OCA at 10:30, 9 March 2017

2017-03-09T10:30:14Z

←Older revision		Revision as of 10:30, 9 March 2017
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	Description: Solution structure of a Bcl-xL S62E mutant		Description: Solution structure of a Bcl-xL S62E mutant
	[[Category: Unreleased Structures]]		[[Category: Unreleased Structures]]
-	[[Category: Follis, A.V]]
	[[Category: Kriwacki, R]]		[[Category: Kriwacki, R]]
		+	[[Category: Follis, A.V]]

OCA at 11:07, 21 September 2016

2016-09-21T11:07:43Z

←Older revision		Revision as of 11:07, 21 September 2016
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	'''Unreleased structure'''		'''Unreleased structure'''

-	The entry 5l1y is ON HOLD	+	The entry 5l1y is ON HOLD until Paper Publication

	Authors: Follis, A.V., Kriwacki, R.		Authors: Follis, A.V., Kriwacki, R.

OCA: Protected "5l1y" [edit=sysop:move=sysop]

2016-08-10T14:00:18Z

Protected "5l1y" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:00, 10 August 2016

OCA: New page: '''Unreleased structure''' The entry 5l1y is ON HOLD Authors: Follis, A.V., Kriwacki, R. Description: Solution structure of a Bcl-xL S62E mutant Category: Unreleased Structures [[C...

2016-08-10T14:00:17Z

New page: '''Unreleased structure''' The entry 5l1y is ON HOLD Authors: Follis, A.V., Kriwacki, R. Description: Solution structure of a Bcl-xL S62E mutant Category: Unreleased Structures [[C...

New page

'''Unreleased structure'''

The entry 5l1y is ON HOLD

Authors: Follis, A.V., Kriwacki, R.

Description: Solution structure of a Bcl-xL S62E mutant
[[Category: Unreleased Structures]]
[[Category: Follis, A.V]]
[[Category: Kriwacki, R]]