5l3w - Revision history

OCA at 12:10, 10 January 2024

2024-01-10T12:10:00Z

←Older revision		Revision as of 12:10, 10 January 2024
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	==See Also==		==See Also==
-	*[[Signal recognition particle receptor\|Signal recognition particle receptor]]	+	*[[Signal recognition particle receptor 3D structures\|Signal recognition particle receptor 3D structures]]
	== References ==		== References ==
	<references/>		<references/>

OCA at 16:06, 4 October 2023

2023-10-04T16:06:09Z

←Older revision		Revision as of 16:06, 4 October 2023
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	<StructureSection load='5l3w' size='340' side='right'caption='[[5l3w]], [[Resolution\|resolution]] 2.40Å' scene=''>		<StructureSection load='5l3w' size='340' side='right'caption='[[5l3w]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/~~Atcc_33909 Atcc 33909~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://proteopedia.org/fgij/fg.htm?mol=5L3W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_acidocaldarius Sulfolobus acidocaldarius]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5L3W FirstGlance]. <br>
-	</td></tr><tr id='~~ligand~~'><td class="sblockLbl"><b>[[~~Ligand~~\|~~Ligands~~:]]</b></td><td class="sblockDat" id="~~ligandDat~~">~~<scene name='pdbligand=GDP:GUANOSINE~~-~~5-DIPHOSPHATE'>GDP</scene>~~, ~~<scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>~~</td></tr>	+	</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models\|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution\|Resolution]] 2.4Å</td></tr>
-	<tr id='~~gene~~'><td class="sblockLbl"><b>[[~~Gene~~\|~~Gene~~:]]</b></td><td class="sblockDat">~~ftsY, ATY89_10730, ATZ20_02285 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode~~=~~Info&srchmode~~=5~~&id~~=~~2285 ATCC 33909])~~</td></tr>	+	<tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://proteopedia.org/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [~~http~~://pdbe.org/5l3w PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/5l3w PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=5l3w ProSAT]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [https://pdbe.org/5l3w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [https://www.ebi.ac.uk/pdbsum/5l3w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5l3w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
-	[~~[http~~://www.uniprot.org/uniprot/~~A0A0U3FSX5_9CREN A0A0U3FSX5_9CREN]~~] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).[HAMAP-Rule:MF_00920]	+	[https://www.uniprot.org/uniprot/FTSY_SULAC FTSY_SULAC] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).[HAMAP-Rule:MF_00920]
	<div style="background-color:#fffaf0;">		<div style="background-color:#fffaf0;">
	== Publication Abstract from PubMed ==		== Publication Abstract from PubMed ==
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	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
-	[[Category: Atcc 33909]]
	[[Category: Large Structures]]		[[Category: Large Structures]]
-	[[Category: ~~Bange, G~~]]	+	[[Category: Sulfolobus acidocaldarius]]
-	[[Category: ~~Sinning, I~~]]	+	[[Category: Bange G]]
-	[[Category: ~~Wild, K~~]]	+	[[Category: Sinning I]]
-	[[Category: ~~Co-translational protein targeting]]~~	+	[[Category: Wild K]]
-	~~[[Category: Gtpase]]~~	+
-	~~[[Category: Protein transport]]~~	+
-	~~[[Category: Signal recognition particle~~]]	+

OCA at 06:42, 5 August 2020

2020-08-05T06:42:55Z

←Older revision		Revision as of 06:42, 5 August 2020
Line 1:		Line 1:

	==Structure of the crenarchaeal FtsY GTPase bound to GDP==		==Structure of the crenarchaeal FtsY GTPase bound to GDP==
-	<StructureSection load='5l3w' size='340' side='right' caption='[[5l3w]], [[Resolution\|resolution]] 2.40Å' scene=''>	+	<StructureSection load='5l3w' size='340' side='right'caption='[[5l3w]], [[Resolution\|resolution]] 2.40Å' scene=''>
	== Structural highlights ==		== Structural highlights ==
-	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5L3W FirstGlance]. <br>	+	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_33909 Atcc 33909]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5L3W FirstGlance]. <br>
-	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>	+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [http://pdbe.org/5l3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [http://www.ebi.ac.uk/pdbsum/5l3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l3w ProSAT]</span></td></tr>	+	<tr id='gene'><td class="sblockLbl"><b>[[Gene\|Gene:]]</b></td><td class="sblockDat">ftsY, ATY89_10730, ATZ20_02285 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2285 ATCC 33909])</td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [http://pdbe.org/5l3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [http://www.ebi.ac.uk/pdbsum/5l3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l3w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==
Line 18:		Line 19:
	</div>		</div>
	<div class="pdbe-citations 5l3w" style="background-color:#fffaf0;"></div>		<div class="pdbe-citations 5l3w" style="background-color:#fffaf0;"></div>
		+
		+	==See Also==
		+	*[[Signal recognition particle receptor\|Signal recognition particle receptor]]
	== References ==		== References ==
	<references/>		<references/>
	__TOC__		__TOC__
	</StructureSection>		</StructureSection>
		+	[[Category: Atcc 33909]]
		+	[[Category: Large Structures]]
	[[Category: Bange, G]]		[[Category: Bange, G]]
	[[Category: Sinning, I]]		[[Category: Sinning, I]]

OCA at 06:38, 26 July 2016

2016-07-26T06:38:54Z

←Older revision		Revision as of 06:38, 26 July 2016
Line 5:		Line 5:
	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L3W FirstGlance]. <br>		<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L3W FirstGlance]. <br>
	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>		</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [http://pdbe.org/5l3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [http://www.ebi.ac.uk/pdbsum/5l3w PDBsum]</span></td></tr>	+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [http://pdbe.org/5l3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [http://www.ebi.ac.uk/pdbsum/5l3w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5l3w ProSAT]</span></td></tr>
	</table>		</table>
	== Function ==		== Function ==

OCA at 15:29, 20 June 2016

2016-06-20T15:29:23Z

←Older revision		Revision as of 15:29, 20 June 2016
Line 1:		Line 1:
-	'''Unreleased structure'''

-	~~The entry~~ 5l3w is ~~ON HOLD~~	+	==Structure of the crenarchaeal FtsY GTPase bound to GDP==
		+	<StructureSection load='5l3w' size='340' side='right' caption='[[5l3w]], [[Resolution\|resolution]] 2.40Å' scene=''>
		+	== Structural highlights ==
		+	<table><tr><td colspan='2'>[[5l3w]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5L3W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5L3W FirstGlance]. <br>
		+	</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand\|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
		+	<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5l3w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5l3w OCA], [http://pdbe.org/5l3w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5l3w RCSB], [http://www.ebi.ac.uk/pdbsum/5l3w PDBsum]</span></td></tr>
		+	</table>
		+	== Function ==
		+	[[http://www.uniprot.org/uniprot/A0A0U3FSX5_9CREN A0A0U3FSX5_9CREN]] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).[HAMAP-Rule:MF_00920]
		+	<div style="background-color:#fffaf0;">
		+	== Publication Abstract from PubMed ==
		+	The signal recognition particle (SRP) is a ribonucleoprotein complex with a key role in targeting and insertion of membrane proteins. The two SRP GTPases, SRP54 (Ffh in bacteria) and FtsY (SRalpha in eukaryotes), form the core of the targeting complex (TC) regulating the SRP cycle. The architecture of the TC and its stimulation by RNA has been described for the bacterial SRP system while this information is lacking for other domains of life. Here, we present the crystal structures of the GTPase heterodimers of archaeal (Sulfolobus solfataricus), eukaryotic (Homo sapiens), and chloroplast (Arabidopsis thaliana) SRP systems. The comprehensive structural comparison combined with Brownian dynamics simulations of TC formation allows for the description of the general blueprint and of specific adaptations of the quasi-symmetric heterodimer. Our work defines conserved external nucleotide-binding sites for SRP GTPase activation by RNA. Structural analyses of the GDP-bound, post-hydrolysis states reveal a conserved, magnesium-sensitive switch within the I-box. Overall, we provide a general model for SRP cycle regulation by RNA.

-	~~Authors: Bange, G~~., Wild, K., ~~Sinning~~, I.	+	Structural Basis for Conserved Regulation and Adaptation of the Signal Recognition Particle Targeting Complex.,Wild K, Bange G, Motiejunas D, Kribelbauer J, Hendricks A, Segnitz B, Wade RC, Sinning I J Mol Biol. 2016 May 27. pii: S0022-2836(16)30184-X. doi:, 10.1016/j.jmb.2016.05.015. PMID:27241309<ref>PMID:27241309</ref>

-	~~Description: Structure~~ of the ~~crenarchaeal FtsY GTPase bound to GDP from Sulfolobus solfataricus~~	+	From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
-	~~[[Category~~: ~~Unreleased Structures]]~~	+	</div>
		+	<div class="pdbe-citations 5l3w" style="background-color:#fffaf0;"></div>
		+	== References ==
		+	<references/>
		+	__TOC__
		+	</StructureSection>
	[[Category: Bange, G]]		[[Category: Bange, G]]
-	[[Category: Wild, K]]
	[[Category: Sinning, I]]		[[Category: Sinning, I]]
		+	[[Category: Wild, K]]
		+	[[Category: Co-translational protein targeting]]
		+	[[Category: Gtpase]]
		+	[[Category: Protein transport]]
		+	[[Category: Signal recognition particle]]

OCA: Protected "5l3w" [edit=sysop:move=sysop]

2016-06-01T14:28:20Z

Protected "5l3w" [edit=sysop:move=sysop]

←Older revision

Revision as of 14:28, 1 June 2016

OCA: New page: '''Unreleased structure''' The entry 5l3w is ON HOLD Authors: Bange, G., Wild, K., Sinning, I. Description: Structure of the crenarchaeal FtsY GTPase bound to GDP from Sulfolobus solfa...

2016-06-01T14:28:18Z

New page: '''Unreleased structure''' The entry 5l3w is ON HOLD Authors: Bange, G., Wild, K., Sinning, I. Description: Structure of the crenarchaeal FtsY GTPase bound to GDP from Sulfolobus solfa...

New page

'''Unreleased structure'''

The entry 5l3w is ON HOLD

Authors: Bange, G., Wild, K., Sinning, I.

Description: Structure of the crenarchaeal FtsY GTPase bound to GDP from Sulfolobus solfataricus
[[Category: Unreleased Structures]]
[[Category: Bange, G]]
[[Category: Wild, K]]
[[Category: Sinning, I]]